dysiherbaine has been researched along with Epilepsy* in 1 studies
1 other study(ies) available for dysiherbaine and Epilepsy
Article | Year |
---|---|
Isolation, structure determination, and synthesis of neodysiherbaine A, a new excitatory amino acid from a marine sponge.
[structure: see text] A new excitatory amino acid, neodysiherbaine A (2), was isolated as a minor constituent of the aqueous extract from the marine sponge Dysidea herbacea. The structure was deduced by spectroscopic methods and established unambiguously by the total synthesis. The present synthesis, including as a key step cross-coupling of the 6/5-bicyclic core with an amino acid residue, is useful in constructing its structural analogues. Topics: Alanine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Dose-Response Relationship, Drug; Epilepsy; Epoxy Compounds; Excitatory Amino Acid Agonists; Heterocyclic Compounds, 3-Ring; Mice; Molecular Structure; Porifera; Radioligand Assay; Rats; Receptors, Kainic Acid; Synaptic Membranes | 2001 |