lactic acid has been researched along with Epilepsy in 58 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In each case, severe metabolic lactic acidosis was identified through routine laboratory diagnostics." | 8.91 | [Lactic acidosis in the postictal state]. ( Admiraal-van de Pas, Y; van Rooij, FJ, 2015) |
| "Epilepsy is a chronic neurological disorder characterized by recurrent seizures, and is highly resistant to medication with up to 40% of patients continuing to experience seizures whilst taking oral antiepileptic drugs." | 5.38 | In vivo biocompatibility and in vitro characterization of poly-lactide-co-glycolide structures containing levetiracetam, for the treatment of epilepsy. ( Campbell, TE; Cook, MJ; Halliday, AJ; McLean, KJ; Nelson, TS; Razal, JM; Wallace, GG, 2012) |
| " In each case, severe metabolic lactic acidosis was identified through routine laboratory diagnostics." | 4.91 | [Lactic acidosis in the postictal state]. ( Admiraal-van de Pas, Y; van Rooij, FJ, 2015) |
| " Furthermore, real-time measurement of lactate and oxygen concentration dynamics concurrently with network electrical activity during status epilepticus induced by 4-aminopyridine (4-AP) demonstrated phasic changes in lactate levels that correlated with bursts of electrical activity, while tonic levels of lactate remained stable during seizures." | 4.84 | Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus. ( Barbosa, RM; Fernandes, E; Gerhardt, GA; Ledo, A, 2024) |
| " He was found to have high anion gap metabolic acidosis with significantly elevated lactate along with an elevated osmolal gap and calcium oxalate crystals in his urine." | 3.85 | Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning? ( Abu Sitta, E; Gaddam, M; Kanzy, A; Velagapudi, RK, 2017) |
| "This article reports the results of research into the activities of lactic acid concentrations in the body fluids of children with progressive encephalopathies (PE) in comparison to patients with non-progressive encephalopathies (NPE) and those with non-progressive encephalopathies with concomitant epilepsy (NPEE)." | 3.71 | Determination of lactic acid level in systemic liquids in children with progressive encephalopathies. ( Bielińska-Bujniewicz, E; Emich-Widera, E; Marszał, E; Pietruszewski, J; Wojaczyńska-Stanek, K, 2002) |
| "Differentiating epileptic seizures from other causes of Transient Loss of Consciousness (TLOC) remains a challenge in the Emergency Department (ED), where it may lead to erroneous administration of anti-epileptic drugs." | 2.82 | Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis. ( Martinez, S; Patel, J; Pourmand, A; Tran, QK; Wright, H, 2022) |
| "Epilepsy is worldwide one of the most common neurologic diseases (prevalence 0." | 2.55 | Epilepsy. ( Fauser, S; Tumani, H, 2017) |
| "Focal cortical dysplasia (FCD) is associated with blood-brain barrier (BBB) dysfunction in patients with difficult-to-treat epilepsy." | 1.72 | Cortical Dysplasia in Rats Provokes Neurovascular Alterations, GLUT1 Dysfunction, and Metabolic Disturbances That Are Sustained Post-Seizure Induction. ( Ghosh, C; Hossain, M; Liu, X; Myers, R; Najm, IM; Nemeth, M; O'Connor, C; Williams, S, 2022) |
| "The effect of seizure activity on CSF lactate concentration in dogs is unknown." | 1.56 | Cerebrospinal fluid lactate concentrations in dogs with seizure disorders. ( Early, PJ; Green, L; Guevar, J; Lau, J; Lee, CS; Mariani, CL; Muñana, KR; Nye, CJ; Olby, NJ; Ruterbories, L; Tokarz, DA; Zidan, N, 2020) |
| "Our data suggest that seizure semiology might impact CSF profiles." | 1.51 | Cerebrospinal fluid changes following epileptic seizures unrelated to inflammation. ( Hannich, M; Saathoff, N; Süße, M; von Podewils, F, 2019) |
| "Rats were subjected to transitory middle cerebral artery occlusion (MCAO) or kainic acid (KA) preconditioning protocol respectively, followed by KA induced epilepsy or lethal MCAO as well as lactate transportation inhibitor injection, with a subsequent evaluation of behavior and infarct volume as well as MCTs expression in rats brain." | 1.51 | Involvement of monocarboxylate transporters in the cross-tolerance between epilepsy and cerebral infarction: A promising choice towards new treatments. ( Bai, J; Gao, C; Gao, L; Li, Z; Wang, R, 2019) |
| "Epilepsy is a chronic neurological disorder that affects approximately 50 million people worldwide." | 1.46 | Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters. ( Becker, HM; Deitmer, JW; Forero-Quintero, LS, 2017) |
| "Findings were correlated with seizure types, seizure etiology (symptomatic, cryptogenic, occasional seizure), and seizure duration." | 1.42 | Effect of epileptic seizures on the cerebrospinal fluid--A systematic retrospective analysis. ( Brettschneider, J; Fauser, S; Hoppner, AC; Jobs, C; Kerling, F; Tumani, H, 2015) |
| "Biotinidase deficiency is a treatable cause of infantile epilepsy and the presentation can be nonspecific." | 1.40 | Abnormal cerebrospinal fluid biochemistry in biotinidase deficiency causing diagnostic conundrum. ( Brown, R; Calvin, J; Hogg, S; Krishnakumar, D; Maw, A; Parker, AP, 2014) |
| "Epilepsy is a chronic neurological disorder characterized by recurrent seizures, and is highly resistant to medication with up to 40% of patients continuing to experience seizures whilst taking oral antiepileptic drugs." | 1.38 | In vivo biocompatibility and in vitro characterization of poly-lactide-co-glycolide structures containing levetiracetam, for the treatment of epilepsy. ( Campbell, TE; Cook, MJ; Halliday, AJ; McLean, KJ; Nelson, TS; Razal, JM; Wallace, GG, 2012) |
| "Some children with mitochondrial disorders manifest only mild or intermittent elevation of lactate levels." | 1.37 | Elevated CSF-lactate is a reliable marker of mitochondrial disorders in children even after brief seizures. ( Honzík, T; Ješina, P; Magner, M; Svandová, I; Szentiványi, K; Tesařová, M; Zeman, J, 2011) |
| "Epilepsy was present in 19 patients." | 1.33 | Mitochondrial dysfunction in autism spectrum disorders: a population-based study. ( Ataíde, A; Borges, L; Diogo, L; Garcia, P; Grazina, M; Marques, C; Miguel, T; Oliveira, CR; Oliveira, G; Vicente, AM, 2005) |
| "In multiple sclerosis, myelopathy, stroke, epilepsy and viral meningitis glutamate, hypoxanthine, xanthine, and uric acid are increased 2-3-fold compared to controls." | 1.30 | Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases. ( Kempski, OS; Lowitzsch, K; Stover, JF, 1997) |
| "Lactic acid concentration has been determined in the cerebrospinal fluid (CSF) of 715 patients suffering from various neurological diseases." | 1.27 | [Importance of cerebrospinal fluid lactate determination in neurological diseases]. ( Busse, O; Hornig, CR; Kaps, M, 1983) |
| "We report a new case of MERRF (myoclonus epilepsy with ragged red fibers) syndrome with basal nuclei calcification on the brain CT scan, without hormonal abnormalities, with high CSF protein and hyperlactacidemia, juvenile onset and death at 18 years." | 1.27 | Mitochondrial encephalo-neuro-myopathy with myoclonus epilepsy, basal nuclei calcification and hyperlactacidemia. ( Cornelio, F; Di Donato, S; Ederli, E; Fabrizi, GM; Federico, A; Guazzi, GC; Manneschi, L, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (18.97) | 18.7374 |
| 1990's | 8 (13.79) | 18.2507 |
| 2000's | 12 (20.69) | 29.6817 |
| 2010's | 18 (31.03) | 24.3611 |
| 2020's | 9 (15.52) | 2.80 |
| Authors | Studies |
|---|---|
| Süße, M | 2 |
| Gag, K | 1 |
| Hamann, L | 1 |
| Hannich, MJ | 1 |
| von Podewils, F | 2 |
| Ghosh, C | 1 |
| Myers, R | 1 |
| O'Connor, C | 1 |
| Williams, S | 1 |
| Liu, X | 1 |
| Hossain, M | 1 |
| Nemeth, M | 1 |
| Najm, IM | 1 |
| Briquet, M | 1 |
| Rocher, AB | 1 |
| Alessandri, M | 1 |
| Rosenberg, N | 1 |
| de Castro Abrantes, H | 1 |
| Wellbourne-Wood, J | 1 |
| Schmuziger, C | 1 |
| Ginet, V | 1 |
| Puyal, J | 1 |
| Pralong, E | 1 |
| Daniel, RT | 1 |
| Offermanns, S | 1 |
| Chatton, JY | 1 |
| Martinez, S | 2 |
| Patel, J | 2 |
| Abdelmonem, A | 1 |
| AlRemeithi, R | 1 |
| Pourmand, A | 2 |
| Tran, QK | 1 |
| Wright, H | 1 |
| Fernandes, E | 1 |
| Ledo, A | 1 |
| Gerhardt, GA | 1 |
| Barbosa, RM | 1 |
| Jin, N | 1 |
| Ziyatdinova, S | 1 |
| Gureviciene, I | 1 |
| Tanila, H | 1 |
| Mariani, CL | 1 |
| Nye, CJ | 1 |
| Ruterbories, L | 1 |
| Tokarz, DA | 1 |
| Green, L | 1 |
| Lau, J | 1 |
| Zidan, N | 1 |
| Early, PJ | 1 |
| Muñana, KR | 1 |
| Olby, NJ | 1 |
| Lee, CS | 1 |
| Guevar, J | 1 |
| Li, X | 1 |
| Peng, B | 1 |
| Hou, C | 1 |
| Li, J | 1 |
| Zeng, Y | 1 |
| Wu, W | 1 |
| Liao, Y | 1 |
| Tian, Y | 1 |
| Chen, WX | 1 |
| Forero-Quintero, LS | 1 |
| Deitmer, JW | 1 |
| Becker, HM | 1 |
| Wu, HC | 1 |
| Dachet, F | 1 |
| Ghoddoussi, F | 1 |
| Bagla, S | 1 |
| Fuerst, D | 1 |
| Stanley, JA | 1 |
| Galloway, MP | 1 |
| Loeb, JA | 1 |
| Chen, Y | 1 |
| Gu, Q | 1 |
| Yue, Z | 1 |
| Crook, JM | 1 |
| Moulton, SE | 1 |
| Cook, MJ | 2 |
| Wallace, GG | 2 |
| Gaddam, M | 1 |
| Velagapudi, RK | 1 |
| Abu Sitta, E | 1 |
| Kanzy, A | 1 |
| Fauser, S | 2 |
| Tumani, H | 2 |
| Bonnet, U | 1 |
| Bingmann, D | 1 |
| Speckmann, EJ | 1 |
| Wiemann, M | 1 |
| Benedicenti, L | 1 |
| Gianotti, G | 1 |
| Galban, EM | 1 |
| Saathoff, N | 1 |
| Hannich, M | 1 |
| Gao, C | 1 |
| Li, Z | 1 |
| Bai, J | 1 |
| Wang, R | 1 |
| Gao, L | 1 |
| Arveladze, GA | 1 |
| Geladze, NM | 1 |
| Sanikidze, TB | 1 |
| Khachapuridze, NS | 1 |
| Bakhtadze, SZ | 1 |
| Jobs, C | 1 |
| Brettschneider, J | 1 |
| Hoppner, AC | 1 |
| Kerling, F | 1 |
| Chatzikonstantinou, A | 1 |
| Ebert, AD | 1 |
| Hennerici, MG | 1 |
| van Rooij, FJ | 1 |
| Admiraal-van de Pas, Y | 1 |
| Liu, J | 1 |
| Saponjian, Y | 1 |
| Mahoney, MM | 1 |
| Staley, KJ | 1 |
| Berdichevsky, Y | 1 |
| Rouach, N | 1 |
| Koulakoff, A | 1 |
| Abudara, V | 1 |
| Willecke, K | 1 |
| Giaume, C | 1 |
| Magner, M | 1 |
| Szentiványi, K | 1 |
| Svandová, I | 1 |
| Ješina, P | 1 |
| Tesařová, M | 1 |
| Honzík, T | 1 |
| Zeman, J | 1 |
| Halliday, AJ | 1 |
| Campbell, TE | 1 |
| Razal, JM | 1 |
| McLean, KJ | 1 |
| Nelson, TS | 1 |
| Yang, H | 1 |
| Peng, YF | 1 |
| Wu, JX | 1 |
| Krishnakumar, D | 1 |
| Maw, A | 1 |
| Brown, R | 1 |
| Hogg, S | 1 |
| Calvin, J | 1 |
| Parker, AP | 1 |
| PROCHOROW, M | 1 |
| Semczuk-Sikora, A | 1 |
| Rogowska, W | 1 |
| Semczuk, M | 1 |
| Overweg-Plandsoen, WC | 1 |
| Groener, JE | 1 |
| Wang, D | 1 |
| Onkenhout, W | 1 |
| Brouwer, OF | 1 |
| Bakker, HD | 1 |
| De Vivo, DC | 1 |
| Kosinovsky, B | 1 |
| Hermon, S | 1 |
| Yoran-Hegesh, R | 1 |
| Golomb, A | 1 |
| Senecky, Y | 1 |
| Goez, H | 1 |
| Kramer, U | 1 |
| Chernov, MF | 1 |
| Kubo, O | 1 |
| Hayashi, M | 1 |
| Izawa, M | 1 |
| Maruyama, T | 1 |
| Usukura, M | 1 |
| Ono, Y | 1 |
| Hori, T | 1 |
| Takakura, K | 1 |
| Oliveira, G | 1 |
| Diogo, L | 1 |
| Grazina, M | 1 |
| Garcia, P | 1 |
| Ataíde, A | 1 |
| Marques, C | 1 |
| Miguel, T | 1 |
| Borges, L | 1 |
| Vicente, AM | 1 |
| Oliveira, CR | 1 |
| Darbin, O | 1 |
| Risso, JJ | 1 |
| Carre, E | 1 |
| Lonjon, M | 1 |
| Naritoku, DK | 1 |
| Siesjö, BK | 2 |
| Hoberg, B | 1 |
| Delank, HW | 1 |
| Hornig, CR | 1 |
| Busse, O | 1 |
| Kaps, M | 1 |
| Panjwani, U | 1 |
| Gupta, HL | 1 |
| Singh, SH | 1 |
| Selvamurthy, W | 1 |
| Rai, UC | 1 |
| Stittsworth, JD | 1 |
| Lanthorn, TH | 1 |
| Prichard, JW | 1 |
| Rosen, BR | 1 |
| Breiter, SN | 1 |
| Arroyo, S | 1 |
| Mathews, VP | 1 |
| Lesser, RP | 1 |
| Bryan, RN | 1 |
| Barker, PB | 1 |
| Campistol, J | 1 |
| García-García, JJ | 1 |
| Lobera, E | 1 |
| Sanmartí, FX | 1 |
| Conill, J | 1 |
| Fernández-Alvarez, E | 1 |
| Stover, JF | 1 |
| Lowitzsch, K | 1 |
| Kempski, OS | 1 |
| Boitier, E | 1 |
| Degoul, F | 1 |
| Desguerre, I | 1 |
| Charpentier, C | 1 |
| François, D | 1 |
| Ponsot, G | 1 |
| Diry, M | 1 |
| Rustin, P | 1 |
| Marsac, C | 1 |
| Shen, J | 1 |
| Novotny, EJ | 1 |
| Rothman, DL | 1 |
| Fornai, F | 1 |
| Bassi, L | 1 |
| Gesi, M | 1 |
| Giorgi, FS | 1 |
| Guerrini, R | 1 |
| Bonaccorsi, I | 1 |
| Alessandrì, MG | 1 |
| McLean, MA | 1 |
| Woermann, FG | 1 |
| Barker, GJ | 1 |
| Duncan, JS | 1 |
| Cendes, F | 1 |
| Pearl, PL | 1 |
| Krasnewich, D | 1 |
| Marszał, E | 1 |
| Wojaczyńska-Stanek, K | 1 |
| Pietruszewski, J | 1 |
| Emich-Widera, E | 1 |
| Bielińska-Bujniewicz, E | 1 |
| Schwartz, RM | 1 |
| Boyes, S | 1 |
| Aynsley-Green, A | 1 |
| Ingvar, M | 1 |
| Wieloch, T | 1 |
| Steidl, L | 1 |
| Tolde, I | 1 |
| Svomová, V | 1 |
| Federico, A | 1 |
| Cornelio, F | 1 |
| Di Donato, S | 1 |
| Ederli, E | 1 |
| Fabrizi, GM | 1 |
| Manneschi, L | 1 |
| Guazzi, GC | 1 |
| Al-Mateen, M | 1 |
| Philippart, M | 1 |
| Shields, WD | 1 |
| Krause, KH | 1 |
| Bonjour, JP | 1 |
| Berlit, P | 1 |
| Kochen, W | 1 |
| Kanayama, M | 1 |
| Sugiyama, N | 1 |
| Morishita, H | 1 |
| Ishikawa, T | 1 |
| Wada, Y | 1 |
| Akiyama, T | 1 |
7 reviews available for lactic acid and Epilepsy
| Article | Year |
|---|---|
Utility of serum lactate on differential diagnosis of seizure-like activity: A systematic review and meta-analysis.
Topics: Adult; Diagnosis, Differential; Electroencephalography; Epilepsy; Humans; Lactic Acid; Prospective S | 2022 |
Epilepsy.
Topics: Animals; Biomarkers; Blood-Brain Barrier; Electroencephalography; Epilepsy; Humans; Lactic Acid; tau | 2017 |
[Lactic acidosis in the postictal state].
Topics: Acidosis, Lactic; Adult; Emergency Service, Hospital; Epilepsy; Humans; Incidence; Lactic Acid; Male | 2015 |
[Glycolysis participates in the mechanism of seizure energy supply and termination].
Topics: Animals; Energy Metabolism; Epilepsy; Glycolysis; Humans; Lactic Acid | 2011 |
Cell damage in the brain: a speculative synthesis.
Topics: Acidosis; Animals; Biological Transport, Active; Brain Ischemia; Calcium; Cell Membrane; Cerebrovasc | 1981 |
Functional study of the brain by NMR.
Topics: Brain; Diffusion; Epilepsy; Forecasting; Glucose; Humans; Image Enhancement; Lactates; Lactic Acid; | 1994 |
Cellular and molecular events underlying epileptic brain damage.
Topics: Acidosis; Animals; Brain; Brain Damage, Chronic; Calcium; Cell Survival; Cerebral Infarction; Electr | 1986 |
3 trials available for lactic acid and Epilepsy
| Article | Year |
|---|---|
Effect of Sahaja yoga practice on stress management in patients of epilepsy.
Topics: Adolescent; Adult; Analysis of Variance; Epilepsy; Female; Galvanic Skin Response; Humans; Hydrogen | 1995 |
In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train.
Topics: 3-Hydroxybutyric Acid; Adolescent; Child; Epilepsy; Humans; Lactic Acid; Magnetic Resonance Spectros | 1998 |
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D | 2000 |
48 other studies available for lactic acid and Epilepsy
| Article | Year |
|---|---|
Time dependency of CSF cell count, lactate and blood-CSF barrier dysfunction after epileptic seizures and status epilepticus.
Topics: Cell Count; Epilepsy; Humans; Lactic Acid; Seizures; Status Epilepticus | 2022 |
Cortical Dysplasia in Rats Provokes Neurovascular Alterations, GLUT1 Dysfunction, and Metabolic Disturbances That Are Sustained Post-Seizure Induction.
Topics: Animals; Blood-Brain Barrier; Epilepsy; Glucose; Glucose Transporter Type 1; Lactic Acid; Malformati | 2022 |
Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue.
Topics: Animals; Brain; Dentate Gyrus; Epilepsy; Excitatory Postsynaptic Potentials; Humans; Lactic Acid; Mi | 2022 |
Use of serum prolactin and lactic acid as a biomarker for epileptic and non-epileptic seizures in the emergency room.
Topics: Biomarkers; Emergency Service, Hospital; Epilepsy; Humans; Lactic Acid; Prolactin; Seizures | 2022 |
Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus.
Topics: 4-Aminopyridine; Animals; Biosensing Techniques; Brain; Epilepsy; Humans; Lactic Acid; Oxygen; Rats; | 2024 |
Response of spike-wave discharges in aged APP/PS1 Alzheimer model mice to antiepileptic, metabolic and cholinergic drugs.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Alzheimer Disease; Animals; Anticonvulsants; Atropine; Dis | 2020 |
Cerebrospinal fluid lactate concentrations in dogs with seizure disorders.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Humans; Lactic Acid; Seizures; Status Epilepticus | 2020 |
Novel compound heterozygous TARS2 variants in a Chinese family with mitochondrial encephalomyopathy: a case report.
Topics: Asian People; Developmental Disabilities; Epilepsy; Family; Gene Expression; Heterozygote; High-Thro | 2020 |
Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters.
Topics: 3-Hydroxybutyric Acid; Animals; Astrocytes; Brain; Diet, Ketogenic; Disease Models, Animal; Epilepsy | 2017 |
Altered metabolomic-genomic signature: A potential noninvasive biomarker of epilepsy.
Topics: Adolescent; Biomarkers; Brain; Child; Child, Preschool; Choline; Creatine; Epilepsy; Female; Genetic | 2017 |
Development of drug-loaded polymer microcapsules for treatment of epilepsy.
Topics: Acetamides; Capsules; Cell Differentiation; Cell Survival; Drug Carriers; Drug Liberation; Electrici | 2017 |
Two gaps too many, three clues too few? Do elevated osmolal and anion gaps with crystalluria always mean ethylene glycol poisoning?
Topics: Acid-Base Equilibrium; Acidosis; Anticonvulsants; Brain Diseases; Calcium Oxalate; Cognitive Dysfunc | 2017 |
Small intraneuronal acidification via short-chain monocarboxylates: First evidence of an inhibitory action on over-excited human neocortical neurons.
Topics: 3-Hydroxybutyric Acid; Carboxylic Acids; Child, Preschool; Electrophysiological Phenomena; Epilepsy; | 2018 |
Comparison between cerebrospinal fluid and serum lactate concentrations in neurologic dogs with and without structural intracranial disease.
Topics: Animals; Brain Neoplasms; Cysts; Dog Diseases; Dogs; Epilepsy; Lactic Acid; Meningoencephalitis; Oti | 2018 |
Cerebrospinal fluid changes following epileptic seizures unrelated to inflammation.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Blood-Brain Barrier; Brain; Electroencephalography; Epilep | 2019 |
Involvement of monocarboxylate transporters in the cross-tolerance between epilepsy and cerebral infarction: A promising choice towards new treatments.
Topics: Animals; Antigens, Nuclear; Cerebral Infarction; Epilepsy; Glial Fibrillary Acidic Protein; Hippocam | 2019 |
[The role of lactate acidosis in the development and treatment of various neurologic syndromes in children and adolescents].
Topics: Acidosis; Adolescent; Child; Child, Preschool; Electroencephalography; Energy Metabolism; Epilepsy; | 2015 |
Effect of epileptic seizures on the cerebrospinal fluid--A systematic retrospective analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Cell Count; Cerebrospinal Fluid; Epilepsy; Fem | 2015 |
Cerebrospinal fluid findings after epileptic seizures.
Topics: Adult; Aged; Brain; Electroencephalography; Epilepsy; Female; Glucose; Humans; Lactic Acid; Magnetic | 2015 |
Epileptogenesis in organotypic hippocampal cultures has limited dependence on culture medium composition.
Topics: Animals; Cell Death; Culture Media; Epilepsy; Hippocampus; L-Lactate Dehydrogenase; Lactic Acid; Neu | 2017 |
Astroglial metabolic networks sustain hippocampal synaptic transmission.
Topics: Animals; Astrocytes; Blood Glucose; Cell Membrane Permeability; Connexin 30; Connexin 43; Connexins; | 2008 |
Elevated CSF-lactate is a reliable marker of mitochondrial disorders in children even after brief seizures.
Topics: Adolescent; Biomarkers; Brain Diseases, Metabolic; Child, Preschool; Epilepsy; Female; Humans; Infan | 2011 |
In vivo biocompatibility and in vitro characterization of poly-lactide-co-glycolide structures containing levetiracetam, for the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Brain; Epilepsy; Glial Fibrillary Acidic Protein; Lactic Acid; Levetiracet | 2012 |
Abnormal cerebrospinal fluid biochemistry in biotinidase deficiency causing diagnostic conundrum.
Topics: Ammonia; Biotinidase Deficiency; Electroencephalography; Epilepsy; Female; Humans; Infant; Lactic Ac | 2014 |
[Effect of thiamine on the level of pyruvic and lactic acids in the blood and cerebrospinal fluid of children with epilepsy].
Topics: Blood Chemical Analysis; Cerebrospinal Fluid; Child; Epilepsy; Humans; Lactates; Lactic Acid; Pyruva | 1962 |
[Influence of valproic acid (depakine I.V.) on human placenta metabolism--experimental model].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Blood Glucose; Embryo, Mammalian; Embryonic and Fetal | 2003 |
GLUT-1 deficiency without epilepsy--an exceptional case.
Topics: Ataxia; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Child; DNA; DNA Mutational Analysis; | 2003 |
The yield of laboratory investigations in children with infantile autism.
Topics: Adolescent; Adult; Amino Acids; Autistic Disorder; Biomarkers; Blood Chemical Analysis; Child; Child | 2005 |
Proton MRS of the peritumoral brain.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain; Brain Edema; Brain Neoplasms; Epilepsy; Female; Huma | 2005 |
Mitochondrial dysfunction in autism spectrum disorders: a population-based study.
Topics: Adolescent; Autistic Disorder; Child; Comorbidity; Cross-Sectional Studies; Epilepsy; Female; Humans | 2005 |
Metabolic changes in rat striatum following convulsive seizures.
Topics: Animals; Corpus Striatum; Electroshock; Energy Metabolism; Epilepsy; Glucose; Glycolysis; Lactic Aci | 2005 |
[Cerebrospinal fluid findings in brain atrophies detected by computer tomography].
Topics: Alcoholism; Atrophy; Brain; Brain Damage, Chronic; Brain Ischemia; Cerebrospinal Fluid Proteins; Enc | 1984 |
[Importance of cerebrospinal fluid lactate determination in neurological diseases].
Topics: Central Nervous System Diseases; Cerebrovascular Disorders; Diagnosis, Differential; Encephalitis; E | 1983 |
Lactate mimics only some effects of D-glucose on epileptic depolarization and long-term synaptic failure.
Topics: Animals; Epilepsy; Glucose; In Vitro Techniques; Lactates; Lactic Acid; Male; Membrane Potentials; N | 1993 |
Proton MR spectroscopy in patients with seizure disorders.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Cerebral Cortex; Child; Child, Preschool; Choline; Creatine | 1994 |
[The Ohtahara's syndrome: a special form of age-dependent epilepsy].
Topics: Adrenocorticotropic Hormone; Age of Onset; Ammonia; Brain; Electroencephalography; Epilepsy; Female; | 1997 |
Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases.
Topics: Adult; Albumins; Central Nervous System Diseases; Cerebrovascular Disorders; Chromatography, High Pr | 1997 |
A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency.
Topics: Cerebellar Ataxia; Child, Preschool; Coenzymes; Electron Transport; Epilepsy; Humans; Kinetics; Lact | 1998 |
Similar increases in extracellular lactic acid in the limbic system during epileptic and/or olfactory stimulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Convulsants; Denervation; Dose-Response Relationship, Drug; Ep | 2000 |
Proton MRS: lactate.
Topics: Animals; Aspartic Acid; Epilepsy; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Protons | 2000 |
Neurologic course of congenital disorders of glycosylation.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Congenital Disorde | 2001 |
Determination of lactic acid level in systemic liquids in children with progressive encephalopathies.
Topics: Adolescent; Brain Diseases; Case-Control Studies; Cerebrovascular Disorders; Child; Child, Preschool | 2002 |
Metabolic effects of three ketogenic diets in the treatment of severe epilepsy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Dietary Fats; Energy Metabolism; | 1989 |
Innovation of the antiepileptic therapy with magnesium lactate.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Lactates; Lactic Acid; Magnesium; Male; Middle Age | 1988 |
Mitochondrial encephalo-neuro-myopathy with myoclonus epilepsy, basal nuclei calcification and hyperlactacidemia.
Topics: Adolescent; Basal Ganglia Diseases; Calcinosis; Epilepsy; Humans; Lactates; Lactic Acid; Male; Mitoc | 1988 |
Rett syndrome. A commonly overlooked progressive encephalopathy in girls.
Topics: Adolescent; Adult; Ataxia; Basal Ganglia Diseases; Brain Diseases; Child; Child, Preschool; Dementia | 1986 |
Biotin status of epileptics.
Topics: Adult; Anticonvulsants; Biotin; Carbon-Carbon Ligases; Carboxy-Lyases; Epilepsy; Female; Humans; Lac | 1985 |
[Effects of valproate on mitochondrial function in epileptic patients].
Topics: Adolescent; Ammonia; Carnitine; Child; Child, Preschool; Epilepsy; Humans; Lactates; Lactic Acid; Mi | 1985 |