1-octanol has been researched along with Epilepsy in 2 studies
1-Octanol: A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and as a raw material for plasticizers. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
octan-1-ol : An octanol carrying the hydroxy group at position 1.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anti-bursting activity of carbenoxolone showed dose-response dependence in the concentration range 50-400 microM." | 1.31 | Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability? ( Klitgaard, H; Margineanu, DG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jahromi, SS | 1 |
| Wentlandt, K | 1 |
| Piran, S | 1 |
| Carlen, PL | 1 |
| Margineanu, DG | 1 |
| Klitgaard, H | 1 |
2 other studies available for 1-octanol and Epilepsy
| Article | Year |
|---|---|
Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.
Topics: 1-Octanol; Action Potentials; Ammonium Chloride; Animals; Anticonvulsants; Carbenoxolone; Connexins; | 2002 |
Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability?
Topics: 1-Octanol; Animals; Carbenoxolone; Diuretics; Dose-Response Relationship, Drug; Epilepsy; Evoked Pot | 2001 |