Page last updated: 2024-10-19

1-octanol and Epilepsy

1-octanol has been researched along with Epilepsy in 2 studies

1-Octanol: A colorless, slightly viscous liquid used as a defoaming or wetting agent. It is also used as a solvent for protective coatings, waxes, and oils, and as a raw material for plasticizers. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
octan-1-ol : An octanol carrying the hydroxy group at position 1.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
" The anti-bursting activity of carbenoxolone showed dose-response dependence in the concentration range 50-400 microM."1.31Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability? ( Klitgaard, H; Margineanu, DG, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jahromi, SS1
Wentlandt, K1
Piran, S1
Carlen, PL1
Margineanu, DG1
Klitgaard, H1

Other Studies

2 other studies available for 1-octanol and Epilepsy

ArticleYear
Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.
    Journal of neurophysiology, 2002, Volume: 88, Issue:4

    Topics: 1-Octanol; Action Potentials; Ammonium Chloride; Animals; Anticonvulsants; Carbenoxolone; Connexins;

2002
Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability?
    Neuropharmacology, 2001, Volume: 41, Issue:3

    Topics: 1-Octanol; Animals; Carbenoxolone; Diuretics; Dose-Response Relationship, Drug; Epilepsy; Evoked Pot

2001