thiamine has been researched along with Epilepsy in 22 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The study looked at how the thiamine supplement impacted pentylenetetrazole (PTZ)-induced seizures in rats and pentylenetetrazole-induced neurotoxicity in the SH-SY5Y cell line." | 8.02 | The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line. ( Ergul, M; Taskiran, AS, 2021) |
| "To report the follow-up findings of 7 children with severe epilepsy as a result of thiamine deficiency in infancy caused by a defective soy-based formula." | 7.75 | Epilepsy in children with infantile thiamine deficiency. ( Bloch-Mimouni, A; Brezner, A; Fattal-Valevski, A; Goldberg-Stern, H; Heyman, E; Inbar, D; Kivity, S; Kramer, U; Strausberg, R, 2009) |
| "Evidence suggests that improving brain inflammation can inhibit the epileptogenesis process and help the emergence of new drugs for the treatment of epilepsy." | 5.72 | Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model. ( Akkaya, R; Filiz, AK; Karabulut, S, 2022) |
| "Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most prevalent encephalopathy in Japanese children." | 5.51 | Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study. ( Fukui, KO; Ishiguro, A; Kashii, H; Kubota, M; Terashima, H, 2019) |
| " The study looked at how the thiamine supplement impacted pentylenetetrazole (PTZ)-induced seizures in rats and pentylenetetrazole-induced neurotoxicity in the SH-SY5Y cell line." | 4.02 | The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line. ( Ergul, M; Taskiran, AS, 2021) |
| " The present study was designed to investigate the effect of acute and chronic administration of thiamine alone and in combination with sub-effective dose of diazepam on pentylenetetrazole (PTZ)-induced tonic-clonic seizures in mice." | 3.91 | Anticonvulsant effects of thiamine on pentylenetetrazole-induced seizure in mice. ( Abed, A; Alinejad, M; Banafshe, HR; Heydari, A; Mesdaghinia, A, 2019) |
| "To report the follow-up findings of 7 children with severe epilepsy as a result of thiamine deficiency in infancy caused by a defective soy-based formula." | 3.75 | Epilepsy in children with infantile thiamine deficiency. ( Bloch-Mimouni, A; Brezner, A; Fattal-Valevski, A; Goldberg-Stern, H; Heyman, E; Inbar, D; Kivity, S; Kramer, U; Strausberg, R, 2009) |
| "Evidence suggests that improving brain inflammation can inhibit the epileptogenesis process and help the emergence of new drugs for the treatment of epilepsy." | 1.72 | Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model. ( Akkaya, R; Filiz, AK; Karabulut, S, 2022) |
| "The diagnosis of Wernicke encephalopathy in our patient is based on increased thiamine requirement due to pregnancy, nystagmus, low transketolase level, and reversal of symptoms after thiamine replacement." | 1.72 | Wernicke encephalopathy with epileptic seizures during pregnancy. ( Beckmann, Y; Mengi, T, 2022) |
| "Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most prevalent encephalopathy in Japanese children." | 1.51 | Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study. ( Fukui, KO; Ishiguro, A; Kashii, H; Kubota, M; Terashima, H, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Karabulut, S | 1 |
| Filiz, AK | 1 |
| Akkaya, R | 1 |
| Mengi, T | 1 |
| Beckmann, Y | 1 |
| Taskiran, AS | 1 |
| Ergul, M | 1 |
| Mesdaghinia, A | 1 |
| Alinejad, M | 1 |
| Abed, A | 1 |
| Heydari, A | 1 |
| Banafshe, HR | 1 |
| Fukui, KO | 1 |
| Kubota, M | 1 |
| Terashima, H | 1 |
| Ishiguro, A | 1 |
| Kashii, H | 1 |
| Turan, MI | 1 |
| Tan, H | 1 |
| Cetin, N | 1 |
| Suleyman, H | 1 |
| Cayir, A | 1 |
| Fattal-Valevski, A | 1 |
| Bloch-Mimouni, A | 1 |
| Kivity, S | 1 |
| Heyman, E | 1 |
| Brezner, A | 1 |
| Strausberg, R | 1 |
| Inbar, D | 1 |
| Kramer, U | 1 |
| Goldberg-Stern, H | 1 |
| Debs, R | 1 |
| Depienne, C | 1 |
| Rastetter, A | 1 |
| Bellanger, A | 1 |
| Degos, B | 1 |
| Galanaud, D | 1 |
| Keren, B | 1 |
| Lyon-Caen, O | 1 |
| Brice, A | 1 |
| Sedel, F | 1 |
| Bøhmer, T | 1 |
| Bøen, A | 1 |
| Høymork, SC | 1 |
| PELLEGRINO, G | 1 |
| PROCHOROW, M | 2 |
| Ranganathan, LN | 1 |
| Ramaratnam, S | 1 |
| Botez, MI | 3 |
| Joyal, C | 1 |
| Maag, U | 1 |
| Bachevalier, J | 1 |
| Botez, T | 1 |
| Ross-Chouinard, A | 1 |
| Lalonde, R | 1 |
| Young, SN | 1 |
| Bettendorff, L | 1 |
| Schoffeniels, E | 2 |
| Naquet, R | 1 |
| Silva-Barrat, C | 1 |
| Riche, D | 1 |
| Ménini, C | 1 |
| Krause, KH | 1 |
| Bonjour, JP | 1 |
| Berlit, P | 1 |
| Kynast, G | 1 |
| Schmidt-Gayk, H | 1 |
| Arab, L | 1 |
| Mietkiewski, K | 1 |
| Kozik, M | 1 |
| Warchol, JB | 1 |
| Pluvinage, R | 1 |
| Demichev, AP | 1 |
1 review available for thiamine and Epilepsy
| Article | Year |
|---|---|
Vitamins for epilepsy.
Topics: Anticonvulsants; Epilepsy; Folic Acid; Humans; Randomized Controlled Trials as Topic; Thiamine; Vita | 2005 |
1 trial available for thiamine and Epilepsy
| Article | Year |
|---|---|
Thiamine and folate treatment of chronic epileptic patients: a controlled study with the Wechsler IQ scale.
Topics: Adult; Brain; Double-Blind Method; Drug Therapy, Combination; Education; Electroencephalography; Epi | 1993 |
20 other studies available for thiamine and Epilepsy
| Article | Year |
|---|---|
Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model.
Topics: Animals; Cognitive Dysfunction; Cyclooxygenase 2; Encephalitis; Epilepsy; Kindling, Neurologic; Male | 2022 |
Wernicke encephalopathy with epileptic seizures during pregnancy.
Topics: Adult; Epilepsy; Female; Humans; Korsakoff Syndrome; Magnetic Resonance Imaging; Pregnancy; Seizures | 2022 |
The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line.
Topics: Animals; Anticonvulsants; Antioxidants; Apoptosis; Brain; Caspase 3; Cell Line; Disease Models, Anim | 2021 |
Anticonvulsant effects of thiamine on pentylenetetrazole-induced seizure in mice.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilep | 2019 |
Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study.
Topics: Brain Diseases; Carnitine; Case-Control Studies; Child, Preschool; Diagnosis, Differential; Disease | 2019 |
Effects of thiamine and thiamine pyrophosphate on epileptic episode model established with caffeine in rats.
Topics: Animals; Brain; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Dose-Response R | 2014 |
Epilepsy in children with infantile thiamine deficiency.
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; Infant Formula; T | 2009 |
Biotin-responsive basal ganglia disease in ethnic Europeans with novel SLC19A3 mutations.
Topics: Adult; Basal Ganglia; Basal Ganglia Diseases; Biotin; Brain Diseases, Metabolic; DNA Mutational Anal | 2010 |
Valproate-induced hyperammonemic encephalopathy, rapidly improved by i.v. carnitine and glucose/thiamine.
Topics: Aged; Ammonia; Anticonvulsants; Brain Diseases, Metabolic; Carnitine; Dose-Response Relationship, Dr | 2010 |
[Effects of pyridoxine deficiency on disposition toward Brown-Sequard's epilepsy].
Topics: Epilepsy; Humans; Personality; Thiamine; Thiamine Deficiency; Vitamin B 6 Deficiency; Vitamin B Defi | 1957 |
[Effect of thiamine on the level of pyruvic and lactic acids in the blood and cerebrospinal fluid of children with epilepsy].
Topics: Blood Chemical Analysis; Cerebrospinal Fluid; Child; Epilepsy; Humans; Lactates; Lactic Acid; Pyruva | 1962 |
The role of thiamine in epilepsy.
Topics: Cerebrospinal Fluid; Epilepsy; Lactates; Pyruvates; Thiamine | 1963 |
Cerebrospinal fluid and blood thiamine concentrations in phenytoin-treated epileptics.
Topics: Epilepsy; Folic Acid; Humans; Middle Aged; Phenytoin; Thiamine | 1982 |
Effects of anticonvulsant treatment and low levels of folate and thiamine on amine metabolites in cerebrospinal fluid.
Topics: Adult; Biogenic Amines; Brain; Electroencephalography; Epilepsy; Female; Folic Acid; Homovanillic Ac | 1991 |
Phosphorylated thiamine derivatives and cortical activity in the baboon Papio papio: effect of intermittent light stimulation.
Topics: Animals; Cerebral Cortex; Electroencephalography; Epilepsy; Papio; Photic Stimulation; Thiamine; Thi | 1989 |
[Molecular aspects of bioelectrogenesis: application to epilepsy].
Topics: Animals; Cats; Cerebral Cortex; Epilepsy; Humans; Light; Mice; Mice, Inbred DBA; Papio; Rats; Sodium | 1985 |
B vitamins in epileptics.
Topics: Adult; Anticonvulsants; Biotin; Epilepsy; Erythrocytes; Female; Humans; Male; Pyridoxal Phosphate; P | 1986 |
Histochemistry of neurosecretion in attempted eliciting of epileptic fits by water load in the rat.
Topics: Acetylcholinesterase; Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Ch | 1974 |
[Study of the therapeutic action of a combination of vitamins B1, B6 and hydroxocobalamin in large doses].
Topics: Adult; Aged; Anemia; Brain Diseases; Epilepsy; Facial Paralysis; Fatty Liver; Female; Hemiplegia; He | 1968 |
[Gayet-Wernicke alcoholic encephalopathy: the most important patterns of development, features of the clinical picture and therapy].
Topics: Acute Disease; Alcohol Amnestic Disorder; Alcoholism; Chronic Disease; Epilepsy; Humans; Movement Di | 1973 |