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1-(3-trifluoromethylphenyl)piperazine and Epilepsy

1-(3-trifluoromethylphenyl)piperazine has been researched along with Epilepsy in 1 studies

1-(3-trifluoromethylphenyl)piperazine: acts as serotonin agonist; structure
1-(3-(trifluoromethyl)phenyl)piperazine : A N-arylpiperazine that is piperazine substituted by a 3-(trifluoromethyl)phenyl group at position 1. A serotonergic agonist used as a recreational drug.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine (20 mg/kg) and TFMPP (5 mg/kg) were administered to rats with pilocarpine-induced epilepsy."7.71Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy. ( Dudek, FE; Hernandez, EJ; Williams, PA, 2002)
"Fluoxetine (20 mg/kg) and TFMPP (5 mg/kg) were administered to rats with pilocarpine-induced epilepsy."3.71Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy. ( Dudek, FE; Hernandez, EJ; Williams, PA, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hernandez, EJ1
Williams, PA1
Dudek, FE1

Other Studies

1 other study available for 1-(3-trifluoromethylphenyl)piperazine and Epilepsy

ArticleYear
Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy.
    Epilepsia, 2002, Volume: 43, Issue:11

    Topics: Animals; Convulsants; Epilepsy; Fluoxetine; Male; Pilocarpine; Piperazines; Rats; Rats, Sprague-Dawl

2002