amlodipine has been researched along with Epilepsy in 2 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was designed to investigate synergistic anticonvulsant effects of pregabalin with amlodipine on acute seizure model of epilepsy in mice." | 7.85 | Synergistic anticonvulsant effects of pregabalin and amlodipine on acute seizure model of epilepsy in mice. ( Khan, RA; Qureshi, IH; Riaz, A; Siddiqui, AA, 2017) |
| " The present study was designed to investigate synergistic anticonvulsant effects of pregabalin with amlodipine on acute seizure model of epilepsy in mice." | 3.85 | Synergistic anticonvulsant effects of pregabalin and amlodipine on acute seizure model of epilepsy in mice. ( Khan, RA; Qureshi, IH; Riaz, A; Siddiqui, AA, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vivier, D | 1 |
| Bennis, K | 1 |
| Lesage, F | 1 |
| Ducki, S | 1 |
| Qureshi, IH | 1 |
| Riaz, A | 1 |
| Khan, RA | 1 |
| Siddiqui, AA | 1 |
1 review available for amlodipine and Epilepsy
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc | 2016 |
1 other study available for amlodipine and Epilepsy
| Article | Year |
|---|---|
Synergistic anticonvulsant effects of pregabalin and amlodipine on acute seizure model of epilepsy in mice.
Topics: Amlodipine; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Drug Therapy, Combinat | 2017 |