spermine has been researched along with Epilepsy in 8 studies
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with spermine, considerably, reversed the PTZ induced alterations." | 5.46 | Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice. ( Kumar, M; Kumar, P, 2017) |
| "Pretreatment with spermine, considerably, reversed the PTZ induced alterations." | 1.46 | Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice. ( Kumar, M; Kumar, P, 2017) |
| "Putrescine has been shown to be catabolized to GABA in brain tissue and astrocytes." | 1.28 | Characteristics of putrescine uptake and subsequent GABA formation in primary cultured astrocytes from normal C57BL/6J and epileptic DBA/2J mouse brain cortices. ( Bureau, M; Grisar, T; Guillaume, D; Laschet, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, M | 1 |
| Kumar, P | 1 |
| SidAhmed-Mezi, M | 1 |
| Pumain, R | 1 |
| Louvel, J | 1 |
| Sokoloff, P | 1 |
| Laschet, J | 2 |
| Doyle, KM | 1 |
| Kirby, BP | 2 |
| Murphy, D | 1 |
| Shaw, GG | 2 |
| Robichaud, LJ | 1 |
| Boxer, PA | 1 |
| Camón, L | 1 |
| de Vera, N | 1 |
| Martínez, E | 1 |
| Kanai, H | 1 |
| Ishida, N | 1 |
| Nakajima, T | 1 |
| Kato, N | 1 |
| Grisar, T | 1 |
| Bureau, M | 1 |
| Guillaume, D | 1 |
8 other studies available for spermine and Epilepsy
| Article | Year |
|---|---|
Protective effect of spermine against pentylenetetrazole kindling epilepsy induced comorbidities in mice.
Topics: Animals; Arginine; Avoidance Learning; Brain; Catecholamines; Comorbidity; Depression; Epilepsy; gam | 2017 |
New therapeutic targets to develop molecules active in drug-resistant epilepsies.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosp | 2010 |
Effect of L-type calcium channel antagonists on spermine-induced CNS excitation in vivo.
Topics: Amines; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System; Convuls | 2005 |
Effect of spermine and N1-dansyl-spermine on epileptiform activity in mouse cortical slices.
Topics: Analysis of Variance; Animals; Cerebral Cortex; Dansyl Compounds; Electric Stimulation; Epilepsy; Fe | 2005 |
Polyamine modulation of excitatory amino acid responses in the rat cortical wedge.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Biogenic Polyamines; | 1993 |
Polyamine metabolism and glutamate receptor agonists-mediated excitotoxicity in the rat brain.
Topics: Animals; Biogenic Polyamines; Biomarkers; Body Weight; Brain; Disease Models, Animal; Epilepsy; Exci | 2001 |
An analogue of Joro spider toxin selectively suppresses hippocampal epileptic discharges induced by quisqualate.
Topics: Animals; Electroencephalography; Epilepsy; Hippocampus; Male; Quisqualic Acid; Rats; Rats, Inbred St | 1992 |
Characteristics of putrescine uptake and subsequent GABA formation in primary cultured astrocytes from normal C57BL/6J and epileptic DBA/2J mouse brain cortices.
Topics: Animals; Astrocytes; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Cerebral Cortex; E | 1992 |