isoguvacine has been researched along with Epilepsy in 3 studies
isoguvacine: A GABA agonist; RN given refers to parent cpd; structure
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tyzio, R | 1 |
| Khalilov, I | 1 |
| Represa, A | 1 |
| Crepel, V | 1 |
| Zilberter, Y | 1 |
| Rheims, S | 1 |
| Aniksztejn, L | 1 |
| Cossart, R | 1 |
| Nardou, R | 1 |
| Mukhtarov, M | 1 |
| Minlebaev, M | 1 |
| Epsztein, J | 1 |
| Milh, M | 1 |
| Becq, H | 1 |
| Jorquera, I | 1 |
| Bulteau, C | 1 |
| Fohlen, M | 1 |
| Oliver, V | 1 |
| Dulac, O | 1 |
| Dorfmüller, G | 1 |
| Delalande, O | 1 |
| Ben-Ari, Y | 1 |
| Khazipov, R | 1 |
| Viitanen, T | 1 |
| Ruusuvuori, E | 1 |
| Kaila, K | 1 |
| Voipio, J | 1 |
| Meldrum, B | 1 |
1 review available for isoguvacine and Epilepsy
| Article | Year |
|---|---|
GABA-agonists as anti-epileptic agents.
Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Disease Models, Animal; Epilepsy; Etomidate | 1981 |
2 other studies available for isoguvacine and Epilepsy
| Article | Year |
|---|---|
Inhibitory actions of the gamma-aminobutyric acid in pediatric Sturge-Weber syndrome.
Topics: Action Potentials; Bumetanide; Cerebral Cortex; Diazepam; Epilepsy; Excitatory Amino Acid Antagonist | 2009 |
The K+-Cl cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus.
Topics: Animals; Anticonvulsants; Barium; Bicarbonates; CA1 Region, Hippocampal; Carbonic Anhydrase Inhibito | 2010 |