alpha-methylhistamine has been researched along with Epilepsy in 2 studies
alpha-methylhistamine: a histamine H3 receptor agonist; RN given refers to parent cpd without isomeric designation
alpha-methylhistamine : An aralkylamino compound that is histamine bearing a methyl substituent at the alpha-position.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, H3Rs may have implications for the treatment of degenerative disorders associated with impaired memory function and may represent a novel therapeutic pharmacological target to tackle cognitive problems associated with the chronic use of antiepileptic drugs." | 1.43 | Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats. ( Kieć-Kononowiczc, K; Saad, A; Sadek, B; Shafiullah, M; Subramanian, D; Łażewska, D, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sadek, B | 1 |
| Saad, A | 1 |
| Subramanian, D | 1 |
| Shafiullah, M | 1 |
| Łażewska, D | 1 |
| Kieć-Kononowiczc, K | 1 |
| Vohora, D | 1 |
| Pal, SN | 1 |
| Pillai, KK | 1 |
2 other studies available for alpha-methylhistamine and Epilepsy
| Article | Year |
|---|---|
Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzothiazoles; Disease Models, Animal; Dose-Response | 2016 |
Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy.
Topics: Animals; Anticonvulsants; Brain; Convulsants; Drug Synergism; Epilepsy; Histamine; Histamine Agonist | 2001 |