phosphoserine has been researched along with Epilepsy in 4 studies
Phosphoserine: The phosphoric acid ester of serine.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anticonvulsant activity of (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) (an antagonist of Group I and an agonist of Group II metabotropic glutamate (mGlu) receptors), of (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid ((1S,3S)-ACPD) (an agonist of Group II mGlu receptors), and of L-serine-O-phosphate (an agonist of Group III mGlu receptors) was studied against sound-induced seizures in genetically epilepsy-prone (GEP) rats following bilateral microinjection into the inferior colliculus." | 3.69 | Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats. ( Chapman, AG; Jane, DE; Meldrum, BS; Tang, E; Yip, PK, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Yuan, J | 1 |
| Yu, X | 1 |
| Liu, X | 1 |
| Tan, C | 1 |
| Chen, Y | 1 |
| Xu, T | 1 |
| Vera, G | 1 |
| Tapia, R | 1 |
| Tang, E | 1 |
| Yip, PK | 2 |
| Chapman, AG | 1 |
| Jane, DE | 1 |
| Meldrum, BS | 2 |
| Rattray, M | 1 |
4 other studies available for phosphoserine and Epilepsy
| Article | Year |
|---|---|
Vezatin regulates seizures by controlling AMPAR-mediated synaptic activity.
Topics: Animals; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Epilepsy; E | 2021 |
Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo.
Topics: 4-Aminopyridine; Amino Acids; Animals; Carboxylic Acids; Chromatography, High Pressure Liquid; Disea | 2012 |
Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats.
Topics: Animals; Behavior, Animal; Cycloleucine; Dose-Response Relationship, Drug; Epilepsy; Female; Glycine | 1997 |
Elevated levels of group-III metabotropic glutamate receptors in the inferior colliculus of genetically epilepsy-prone rats following intracollicular administration of L-serine-O-phosphate.
Topics: Animals; Behavior, Animal; Epilepsy; Female; Genetic Predisposition to Disease; Inferior Colliculi; | 2001 |