orotic acid has been researched along with Epilepsy in 5 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grohmann, K | 1 |
| Lauffer, H | 1 |
| Lauenstein, P | 1 |
| Hoffmann, GF | 1 |
| Seidlitz, G | 1 |
| Häberle, J | 1 |
| KURTH, LE | 1 |
| KOENIG, H | 1 |
| FREYRE, J | 1 |
| Dewar, AJ | 1 |
| Dow, RC | 1 |
| McQueen, JK | 1 |
| Nieper, HA | 1 |
1 trial available for orotic acid and Epilepsy
| Article | Year |
|---|---|
The clinical applications of lithium orotate. A two years study.
Topics: Alcoholism; Biological Transport; Cell Membrane; Clinical Trials as Topic; Depression; Drug Evaluati | 1973 |
4 other studies available for orotic acid and Epilepsy
| Article | Year |
|---|---|
Hereditary orotic aciduria with epilepsy and without megaloblastic anemia.
Topics: Anemia, Megaloblastic; Child, Preschool; Epilepsy; Humans; Male; Metabolic Diseases; Multienzyme Com | 2015 |
Of ammonia and orotic acid and their importance for clinical neuropediatrics.
Topics: Anemia, Megaloblastic; Epilepsy; Humans; Male; Metabolic Diseases; Multienzyme Complexes; Orotate Ph | 2015 |
Frontal lobe encephalopathy with focal seizures produced with pyrimidine analogs.
Topics: Disease; Electroencephalography; Epilepsy; Frontal Lobe; Humans; Orotic Acid; Seizures | 1960 |
RNA and protein metabolism in cobalt-induced epileptogenic lesions in rat brain.
Topics: Animals; Carbon Isotopes; Cobalt; DNA; Electroencephalography; Epilepsy; Leucine; Male; Motor Cortex | 1972 |