ketotifen has been researched along with Epilepsy in 3 studies
Ketotifen: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
ketotifen : An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical reports have shown that some antihistamines, such as ketotifen, occasionally produced seizures, especially in pre-school age children or young patients with epilepsy." | 7.78 | The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats. ( Kanda, T; Takizawa, F; Tamura, T; Yamada, K, 2012) |
| "Clinical reports have shown that some antihistamines, such as ketotifen, occasionally produced seizures, especially in pre-school age children or young patients with epilepsy." | 3.78 | The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats. ( Kanda, T; Takizawa, F; Tamura, T; Yamada, K, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, K | 1 |
| Takizawa, F | 1 |
| Tamura, T | 1 |
| Kanda, T | 1 |
| Yokoyama, H | 1 |
| Hirose, M | 1 |
| Uematsu, M | 1 |
| Haginoya, K | 1 |
| Iinuma, K | 1 |
| Kimura, S | 1 |
| Fujii, Y | 1 |
| Tanaka, T | 1 |
| Harada, C | 1 |
| Hirai, T | 1 |
| Kamei, C | 1 |
3 other studies available for ketotifen and Epilepsy
| Article | Year |
|---|---|
The effect of antihistamines on seizures induced by increasing-current electroshocks: ketotifen, but not olopatadine, promotes the seizures in infant rats.
Topics: Age Factors; Animals; Anti-Allergic Agents; Brain; Caffeine; Central Nervous System Stimulants; Dibe | 2012 |
Ketotifen overdose in infancy associated with development of epilepsy and mild mental retardation.
Topics: Dermatitis, Atopic; Drug Overdose; Epilepsy; Histamine H1 Antagonists; Humans; Infant; Intellectual | 2012 |
Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats.
Topics: Amygdala; Animals; Cetirizine; Diphenhydramine; Electroencephalography; Epilepsy; Histamine H1 Antag | 2003 |