adenine has been researched along with Epilepsy in 6 studies
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epilepsy affects all ages, races, genders, and socioeconomic groups." | 1.56 | PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes. ( Danzer, SC; Gross, C; MacLeod, MC; Tiwari, D; White, AR, 2020) |
| "KD alleviated seizure severity, decreased the number of Fluoro-jade B (FJB)-positive cells in the hippocampus of kindled rats." | 1.48 | Ketogenic diet attenuates neuronal injury via autophagy and mitochondrial pathways in pentylenetetrazol-kindled seizures. ( Hou, Q; Jia, MM; Jiang, Y; Lu, YQ; Qiu, T; Wang, BH; Wang, XH; Zhang, ZX, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| White, AR | 1 |
| Tiwari, D | 1 |
| MacLeod, MC | 1 |
| Danzer, SC | 1 |
| Gross, C | 1 |
| Wang, BH | 1 |
| Hou, Q | 1 |
| Lu, YQ | 1 |
| Jia, MM | 1 |
| Qiu, T | 1 |
| Wang, XH | 1 |
| Zhang, ZX | 1 |
| Jiang, Y | 1 |
| Hall, J | 1 |
| Frenguelli, BG | 1 |
| Kommajosyula, SP | 1 |
| Randall, ME | 1 |
| Faingold, CL | 1 |
| Shen, HY | 1 |
| Li, T | 1 |
| Boison, D | 1 |
| Dupere, JR | 1 |
| Dale, TJ | 1 |
| Starkey, SJ | 1 |
| Xie, X | 1 |
6 other studies available for adenine and Epilepsy
| Article | Year |
|---|---|
PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes.
Topics: Adenine; Animals; Cerebral Cortex; Class I Phosphatidylinositol 3-Kinases; Epilepsy; Female; Hippoca | 2020 |
Ketogenic diet attenuates neuronal injury via autophagy and mitochondrial pathways in pentylenetetrazol-kindled seizures.
Topics: Adenine; Animals; Apoptosis; Autophagy; Caspase 3; Cytochromes c; Diet, Ketogenic; Epilepsy; Hippoca | 2018 |
The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Creatine; Electrophysiological Phenomena; Epile | 2018 |
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats.
Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme In | 2016 |
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of De | 2010 |
The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anticonvulsants; Bra | 1999 |