methanol has been researched along with Epilepsy in 12 studies
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hence, the methanol extract was further explored for its anticonvulsant potential in pentylenetetrazole (PTZ) induced acute seizures in mice." | 8.31 | Anticonvulsant potential of Grewia tiliaefolia in pentylenetetrazole induced epilepsy: insights from in vivo and in silico studies. ( Arora, S; Kaur, S; Kumar, N; Rajput, A; Sharma, P; Singh Bedi, PM; Singh, B; Singh, H; Singh, S; Singh, T, 2023) |
| " In the pharmacodynamic interaction study, seizures were induced using pentylenetetrazole (PTZ) (60 mg/kg, i." | 8.02 | Pharmacodynamic and pharmacokinetic interactions of hydroalcoholic leaf extract of Centella asiatica with valproate and phenytoin in experimental models of epilepsy in rats. ( Agarwal, A; Arora, R; Ganeshan N, S; Gupta, YK; Kaleekal, T; Kumar, R; Sarangi, SC, 2021) |
| "In six-hertz-seizure test the MeCO (25, 50, 100 and 200mg/kg) and AeCO (50, 100, 200, 400 and 800mg/kg) showed significant protection compared to control group, and MeCO was more potent than AeCO." | 5.46 | Ameliorative potential of Colebrookea oppositifolia methanolic root extract against experimental models of epilepsy: Possible role of GABA mediated mechanism. ( Prasad, NBL; Venkataranganna, MV; Viswanatha, GL, 2017) |
| " Hence, the methanol extract was further explored for its anticonvulsant potential in pentylenetetrazole (PTZ) induced acute seizures in mice." | 4.31 | Anticonvulsant potential of Grewia tiliaefolia in pentylenetetrazole induced epilepsy: insights from in vivo and in silico studies. ( Arora, S; Kaur, S; Kumar, N; Rajput, A; Sharma, P; Singh Bedi, PM; Singh, B; Singh, H; Singh, S; Singh, T, 2023) |
| " In the pharmacodynamic interaction study, seizures were induced using pentylenetetrazole (PTZ) (60 mg/kg, i." | 4.02 | Pharmacodynamic and pharmacokinetic interactions of hydroalcoholic leaf extract of Centella asiatica with valproate and phenytoin in experimental models of epilepsy in rats. ( Agarwal, A; Arora, R; Ganeshan N, S; Gupta, YK; Kaleekal, T; Kumar, R; Sarangi, SC, 2021) |
| "camptopus in acute models of epileptic seizures in Wistar rats." | 1.62 | Anticonvulsant effects of the aqueous and methanol extracts from the stem bark of Psychotria camptopus Verdc. (Rubiacaea) in rats. ( Chouna, R; Dongmo, AK; Fokoua, AR; Kaptué Wuyt, A; Ndjenda, MK; Nguelefack, TB; Nkeng-Efouet, PA; Tatsinkou Bomba, FD, 2021) |
| "In six-hertz-seizure test the MeCO (25, 50, 100 and 200mg/kg) and AeCO (50, 100, 200, 400 and 800mg/kg) showed significant protection compared to control group, and MeCO was more potent than AeCO." | 1.46 | Ameliorative potential of Colebrookea oppositifolia methanolic root extract against experimental models of epilepsy: Possible role of GABA mediated mechanism. ( Prasad, NBL; Venkataranganna, MV; Viswanatha, GL, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rajput, A | 1 |
| Sharma, P | 1 |
| Kumar, N | 1 |
| Singh, H | 1 |
| Singh, T | 1 |
| Singh, S | 1 |
| Singh Bedi, PM | 1 |
| Singh, B | 1 |
| Arora, S | 1 |
| Kaur, S | 1 |
| Kumar, R | 1 |
| Arora, R | 1 |
| Sarangi, SC | 1 |
| Ganeshan N, S | 1 |
| Agarwal, A | 1 |
| Kaleekal, T | 1 |
| Gupta, YK | 1 |
| Fokoua, AR | 1 |
| Ndjenda, MK | 1 |
| Kaptué Wuyt, A | 1 |
| Tatsinkou Bomba, FD | 1 |
| Dongmo, AK | 1 |
| Chouna, R | 1 |
| Nkeng-Efouet, PA | 1 |
| Nguelefack, TB | 1 |
| Viswanatha, GL | 1 |
| Venkataranganna, MV | 1 |
| Prasad, NBL | 1 |
| van Gaal, JC | 1 |
| Petru, R | 1 |
| Sie, LT | 1 |
| Soysal, D | 1 |
| Yersal Kabayegit, O | 1 |
| Yilmaz, S | 1 |
| Tatar, E | 1 |
| Ozatli, T | 1 |
| Yildiz, B | 1 |
| Ugur, O | 1 |
| Kim, HJ | 1 |
| Moon, KD | 1 |
| Oh, SY | 1 |
| Kim, SP | 1 |
| Lee, SR | 1 |
| Lees, F | 1 |
| Poli, S | 1 |
| Vincent, A | 1 |
| Perret, C | 1 |
| Romano, F | 1 |
| Meldrum, BS | 1 |
| Quadbeck, G | 1 |
2 reviews available for methanol and Epilepsy
| Article | Year |
|---|---|
Alcohol and the nervous system.
Topics: Acute Disease; Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoh | 1975 |
[Lactic acidosis].
Topics: Acidosis; Bicarbonates; Biguanides; Diabetes Mellitus; Epilepsy; Ethanol; Fructose; Heart Failure; H | 1985 |
10 other studies available for methanol and Epilepsy
| Article | Year |
|---|---|
Anticonvulsant potential of Grewia tiliaefolia in pentylenetetrazole induced epilepsy: insights from in vivo and in silico studies.
Topics: Animals; Anticonvulsants; Antioxidants; Chloroform; Epilepsy; Gallic Acid; gamma-Aminobutyric Acid; | 2023 |
Pharmacodynamic and pharmacokinetic interactions of hydroalcoholic leaf extract of Centella asiatica with valproate and phenytoin in experimental models of epilepsy in rats.
Topics: Adjuvants, Pharmaceutic; Animals; Anticonvulsants; Behavior, Animal; Centella; Cognitive Dysfunction | 2021 |
Anticonvulsant effects of the aqueous and methanol extracts from the stem bark of Psychotria camptopus Verdc. (Rubiacaea) in rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Epilepsy; Methanol; Mi | 2021 |
Ameliorative potential of Colebrookea oppositifolia methanolic root extract against experimental models of epilepsy: Possible role of GABA mediated mechanism.
Topics: Animals; Anticonvulsants; Brain; Electroshock; Epilepsy; gamma-Aminobutyric Acid; Lamiaceae; Medicin | 2017 |
[An infant with unexplained epilepsy].
Topics: Child Abuse; Delayed Diagnosis; Diagnosis, Differential; Disinfectants; Epilepsy; Ethanol; Humans; I | 2010 |
Transdermal methanol intoxication: a case report.
Topics: Administration, Cutaneous; Epilepsy; Fatal Outcome; Female; Glasgow Coma Scale; Humans; Methanol; Mi | 2007 |
Ether fraction of methanol extracts of Gastrodia elata, a traditional medicinal herb, protects against kainic acid-induced neuronal damage in the mouse hippocampus.
Topics: Animals; Dose-Response Relationship, Drug; Epilepsy; Ether; Excitatory Amino Acid Agonists; Hippocam | 2001 |
[Therapeutic experience with the use of piritinol (Encephabol) in geriatrics].
Topics: Aged; Asthenia; Cognition Disorders; Dementia; Epilepsy; Female; Humans; Intracranial Arterioscleros | 1970 |
Convulsive effects of 4-deoxypyridoxine in photosensitive baboons (Papio papio).
Topics: Animals; Electroencephalography; Epilepsy; Light; Methanol; Myoclonus; Papio; Pyridines; Seizures | 1971 |
Clinical importance of alterations in barrier.
Topics: Adult; Age Factors; Biological Transport, Active; Blood-Brain Barrier; Brain; Cerebrovascular Circul | 1968 |