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aminoglutethimide and Epilepsy

aminoglutethimide has been researched along with Epilepsy in 8 studies

Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
" The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures."7.73Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005)
" The combination of AGLD (5 mg/kg) with phenobarbital (PB, applied at its subeffective dose of 15 mg/kg) significantly shortened motor seizure and afterdischarge duration in amygdala-kindled seizures."3.73Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats. ( Borowicz, KK; Czuczwar, SJ, 2005)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
AGUILAR, JA1
MARTIN, HL1
McNAUGHTON, FL1
BAUER, RB1
MEYER, JS1
VERDEAU-PAILLES, J1
LAVECK, GD1
PEARCE, KI1
Borowicz, KK1
Czuczwar, SJ1
Jannasch, R1
LeMaire, WJ1
Cleveland, WW1
Bejar, RL1
Marsh, JM1
Fishman, L1

Reviews

1 review available for aminoglutethimide and Epilepsy

ArticleYear
[Antiepileptics. 39].
    Pharmazeutische Praxis, 1969, Volume: 10

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Aminoglutethimide; Anticonvulsants; Barbiturates; Carbam

1969

Other Studies

7 other studies available for aminoglutethimide and Epilepsy

ArticleYear
Aminoglutethimide in the treatment of epilepsy.
    Canadian Medical Association journal, 1961, Feb-18, Volume: 84

    Topics: Aminoglutethimide; Anticonvulsants; Epilepsy

1961
Clinical evaluation of elipten: a new anticonvulsant drug for epilepsy.
    Journal - Michigan State Medical Society, 1960, Volume: 59

    Topics: Aminoglutethimide; Anticonvulsants; Epilepsy

1960
[A new anticonvulsant: the preparation Ciba 16-0-38 or elipten. Its importance in refractory epilepsy].
    Annales medico-psychologiques, 1961, Volume: 119(1)

    Topics: Aminoglutethimide; Anticonvulsants; Epilepsy

1961
Elipten in the treatment of organic epilepsy.
    Diseases of the nervous system, 1960, Volume: 21

    Topics: Aminoglutethimide; Anticoagulants; Epilepsy

1960
Elipten: A clinical evaluation of a new anticonvulsant. Preliminary report.
    Canadian Medical Association journal, 1960, May-07, Volume: 82

    Topics: Aminoglutethimide; Anticonvulsants; Epilepsy

1960
Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:7

    Topics: Adrenergic Agents; Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Clonazepam; Disease Models

2005
Aminoglutethimide: a possible cause of pseudohermaphroiditism in females.
    American journal of diseases of children (1960), 1972, Volume: 124, Issue:3

    Topics: Adult; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Child, Preschool; Disorders o

1972