pyruvic acid has been researched along with Epilepsy in 11 studies
Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epilepsy was present in 19 patients." | 1.33 | Mitochondrial dysfunction in autism spectrum disorders: a population-based study. ( Ataíde, A; Borges, L; Diogo, L; Garcia, P; Grazina, M; Marques, C; Miguel, T; Oliveira, CR; Oliveira, G; Vicente, AM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, N | 1 |
| Ziyatdinova, S | 1 |
| Gureviciene, I | 1 |
| Tanila, H | 1 |
| Popova, I | 1 |
| Malkov, A | 1 |
| Ivanov, AI | 1 |
| Samokhina, E | 1 |
| Buldakova, S | 1 |
| Gubkina, O | 1 |
| Osypov, A | 1 |
| Muhammadiev, RS | 1 |
| Zilberter, T | 1 |
| Molchanov, M | 1 |
| Paskevich, S | 1 |
| Zilberter, M | 1 |
| Zilberter, Y | 1 |
| BARRETO, RC | 1 |
| SABINO, SO | 1 |
| BITTENCOURT, RS | 1 |
| Kosinovsky, B | 1 |
| Hermon, S | 1 |
| Yoran-Hegesh, R | 1 |
| Golomb, A | 1 |
| Senecky, Y | 1 |
| Goez, H | 1 |
| Kramer, U | 1 |
| Oliveira, G | 1 |
| Diogo, L | 1 |
| Grazina, M | 1 |
| Garcia, P | 1 |
| Ataíde, A | 1 |
| Marques, C | 1 |
| Miguel, T | 1 |
| Borges, L | 1 |
| Vicente, AM | 1 |
| Oliveira, CR | 1 |
| Darbin, O | 1 |
| Risso, JJ | 1 |
| Carre, E | 1 |
| Lonjon, M | 1 |
| Naritoku, DK | 1 |
| Gasior, M | 1 |
| French, A | 1 |
| Joy, MT | 1 |
| Tang, RS | 1 |
| Hartman, AL | 1 |
| Rogawski, MA | 1 |
| Kim, TY | 1 |
| Yi, JS | 1 |
| Chung, SJ | 1 |
| Kim, DK | 1 |
| Byun, HR | 1 |
| Lee, JY | 1 |
| Koh, JY | 1 |
| Campistol, J | 1 |
| García-García, JJ | 1 |
| Lobera, E | 1 |
| Sanmartí, FX | 1 |
| Conill, J | 1 |
| Fernández-Alvarez, E | 1 |
| Schwartz, RM | 1 |
| Boyes, S | 1 |
| Aynsley-Green, A | 1 |
| Siesjö, BK | 1 |
| Ingvar, M | 1 |
| Wieloch, T | 1 |
1 review available for pyruvic acid and Epilepsy
| Article | Year |
|---|---|
Cellular and molecular events underlying epileptic brain damage.
Topics: Acidosis; Animals; Brain; Brain Damage, Chronic; Calcium; Cell Survival; Cerebral Infarction; Electr | 1986 |
10 other studies available for pyruvic acid and Epilepsy
| Article | Year |
|---|---|
Response of spike-wave discharges in aged APP/PS1 Alzheimer model mice to antiepileptic, metabolic and cholinergic drugs.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Alzheimer Disease; Animals; Anticonvulsants; Atropine; Dis | 2020 |
Metabolic correction by pyruvate halts acquired epilepsy in multiple rodent models.
Topics: Alzheimer Disease; Animals; Anticonvulsants; Brain; Brain Waves; Drug Evaluation, Preclinical; Epile | 2017 |
Pyruvate metabolism in epileptic tuberculous patients.
Topics: Biochemical Phenomena; Epilepsy; Humans; Pyruvates; Pyruvic Acid; Tuberculosis; Tuberculosis, Pulmon | 1962 |
The yield of laboratory investigations in children with infantile autism.
Topics: Adolescent; Adult; Amino Acids; Autistic Disorder; Biomarkers; Blood Chemical Analysis; Child; Child | 2005 |
Mitochondrial dysfunction in autism spectrum disorders: a population-based study.
Topics: Adolescent; Autistic Disorder; Child; Comorbidity; Cross-Sectional Studies; Epilepsy; Female; Humans | 2005 |
Metabolic changes in rat striatum following convulsive seizures.
Topics: Animals; Corpus Striatum; Electroshock; Energy Metabolism; Epilepsy; Glucose; Glycolysis; Lactic Aci | 2005 |
The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid.
Topics: Acetone; Animals; Anticonvulsants; Diet Therapy; Disease Models, Animal; Epilepsy; Ketone Bodies; Ma | 2007 |
Pyruvate protects against kainate-induced epileptic brain damage in rats.
Topics: Animals; Brain Damage, Chronic; Cell Death; Epilepsy; Excitatory Amino Acid Agonists; Hippocampus; H | 2007 |
[The Ohtahara's syndrome: a special form of age-dependent epilepsy].
Topics: Adrenocorticotropic Hormone; Age of Onset; Ammonia; Brain; Electroencephalography; Epilepsy; Female; | 1997 |
Metabolic effects of three ketogenic diets in the treatment of severe epilepsy.
Topics: Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Dietary Fats; Energy Metabolism; | 1989 |