Page last updated: 2024-12-06

azo rubin s

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Azo Rubin S is a synthetic dye with a complex chemical structure that includes azo groups. It is used in a variety of applications, including textile dyeing, leather tanning, and food coloring. The synthesis of Azo Rubin S typically involves a multi-step process that begins with the coupling of diazonium salts with aromatic amines. The dye is known to exhibit some degree of toxicity and may pose environmental risks. The study of Azo Rubin S is important for understanding its potential health and environmental impacts, as well as for exploring alternative dyes that are safer and more sustainable.'

Acid red 14: a wster pollutant; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

azo rubin S: RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID19118
CHEMBL ID1552837
CHEBI ID82414
SCHEMBL ID342870
SCHEMBL ID42707
MeSH IDM0049332
PubMed CID19119
CHEMBL ID1624506
CHEBI ID180754
SCHEMBL ID110093
SCHEMBL ID15115265
SCHEMBL ID21274168
MeSH IDM0049332

Synonyms (217)

Synonym
azorubine
disodium 4-hydroxy-3-[(e)-(4-sulfonato-1-naphthyl)diazenyl]naphthalene-1-sulfonate
acid brilliant rubine a2g conc.
fruit red a extra yellowish geigy
acid chrome blue fbs
2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonic acid, disodium salt
omega chrome blue fb
c.i. acid red 14, disodium salt
hd carmoisine
nacarat
eniacid brilliant rubine 3b
acid chrome blue ba
crimson 2embl
disodium 2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonate
acid chrome blue 2r
erio rubine b
acid chrome blue ba-cf
tertrochrome blue fb
11959 red
nsc-7807
tertracid red ca
poloxal red 2bred #1411959 red
c.i. 14720
solochrome blue fb
e 122
solar rubine
standacol carmoisine
hd carmoisine supra
acid red 2c
c.i. acid red no. 14
carmoisine w
nci-c53849
diadem chrome blue r
amacid chrome blue r
nacarat extra pure a
azo rubine xx
brilliant crimson 2r.fq
ext d and c red no. 10
brilliant carmoisine
lighthouse chrome blue 2r
hidacid azo rubine
carmoisine las
carmoisine grn
azo rubine extra lc
karmesin
azo rubine af
carmoisine bss
diadem chrome blue g
azo rubine for food
food red 5
acid brilliant rubine 2g
nylomine acid red p4b
azo rubine lz
c.i. acid red 14
carmoisine supra
java rubine n
edicol supra carmoisine w
kiton crimson 2r
kenachrome blue 2r
amacid carmoisine b
acid rubine extra
azorubin
acid red 14
atul crystal red f
edicol supra carmoisine ws
brilliant acid rubine m
carmoisine ws
azo rubine
hexacol carmoisine conc.
kiton rubine r
acid fast red fb
chrome fast blue 2r
acid rubine
3567-69-9
crimson embl
azo rubin extra
carmoisine
atul acid crystal red
carmoisine ba-cf
acetacid red b
carmoisine ba
bucacid azo rubine
brilliant crimson red
chromotrop fb
azo rubine s specially pure
carmoisine s
cilefa rubine r
c.i. food red 3
certicol carmoisine s
neklacid rubine w
fenazo red c
carmoisine fu
airedale carmoisine
brasilan azo rubine 2ns
hispacid rubine f
chromotrope fb
pontacyl rubine r
azo rubine (biological stain)
azo rubin xx
calcocid rubine xx
neklacid azorubine w
hexacol carmoisine
acid brilliant rubine 2gt
nacarat a export
eurocert azorubine
l. red z 3040
1-naphthalenesulfonic acid, 4-hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-, disodium salt
e122
ci food red 3
2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonic acid, disodium salt
nacarat extra pure 1a
carmoisin [german]
poloxal red 2b
4-hydroxy-3-((4-sulpho-1-naphthalenyl)azo)-1-naphthalenesulphonic acid, disodium salt
ext d & c red no. 10
4-hydroxy-3,4'-azodi-1-naphthalenesulfonic acid, disodium salt
ci acid red 14, disodium salt
ci 14720
1-naphthalenesulfonic acid, 4-hydroxy-3,4'-azodi-, disodium salt
4-hydroxy-3,4'-azodi-1-naphthalenesulphonic acid, disodium salt
hsdb 4137
ccris 163
nacarat (van)
4-hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-1-naphthalenesulfonic acid, disodium salt
disodium 2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonate
cerven potravinarska 3 [czech]
ci acid red
nsc 7807
disodium salt of 2-(4-sulpho-1-naphthylazo)-1-naphthol-4-sulphonic acid
einecs 222-657-4
red #14
schultz nr. 208 [german]
cerven kysela 14 [czech]
brilliant crimson 2r. fq
disodium 4-hydroxy-3-((4-sulphonatonaphthyl)azo)naphthalenesulphonate
chromotrope fb, dye content 50 %
NCGC00164088-01
A0580
carmoisine b
AKOS004901410
C19358
ci acid red 14
schultz nr. 208
c.i. mordant blue 79
cerven potravinarska 3
carmoisin
1-naphthalenesulfonic acid, 4-hydroxy-3-(2-(4-sulfo-1-naphthalenyl)diazenyl)-, sodium salt (1:2)
dr4641l47f ,
cerven kysela 14
unii-dr4641l47f
azorubine [usp-rs]
carmoisine [iarc]
carmoisine [mart.]
ci 14720 [inci]
ci-(1975)no.14720
ci-food red 3
carmoisine e122
c.i. acid red 14 [hsdb]
carmoisine (e122)
e-122
azorubine [mi]
ins no.122
ins-122
acid red 14 [inci]
SCHEMBL342870
SCHEMBL42707
CHEBI:82414 ,
CHEMBL1552837
mfcd00003978
DTXSID3021225
1-naphthalenesulfonic acid, 4-hydroxy-3-[2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:2)
carmoisine, analytical standard
sodium 4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate
azorubin (e122)
sodium (e)-4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate
Q409676
azorubin (e122) 100 microg/ml in acetonitrile
D88283
disodium;4-hydroxy-3-[(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate
azo rubine (50per cent dye content)
AKOS040759294
4-hydroxy-3-[(4-sulonaphthalen-1-yl)diazenyl]naphthalene-1-sulonic acid
CHEBI:180754
solochrome brilliant blue
carmoisine aluminum lake
acid red 2s
azo rubin s
4-hydroxy-3-[(e)-(4-sulfo-1-naphthyl)azo]naphthalene-1-sulfonic acid
2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonate
nsc7807
carmoisine aluminium lake
7-hydroxy-8-((4-sulfo-1-naphthyl)azo)-5-naphthalenesulfonic acid
13613-55-3
4-hydroxy-3-((4-sulpho-1-naphthyl)azo)naphthalene-1-sulphonic acid
einecs 237-098-1
unii-83344c2n7u
83344c2n7u ,
SCHEMBL110093
1-naphthalenesulfonic acid, 4-hydroxy-3-((4-sulfo-1-naphthalenyl)azo)-
1-naphthol-4-sulfonic acid, 2-(4-sulfo-1-naphthylazo)-
1-naphthalenesulfonic acid, 4-hydroxy-3-(2-(4-sulfo-1-naphthalenyl)diazenyl)-
c.i. acid red 14 (free acid)
c.i. acid red 14, free acid
c.i. acid red 14 free acid
2-(4-sulfo-1-naphthylazo)-1-naphthol-4-sulfonic acid
DTXSID8047216
SCHEMBL15115265
CHEMBL1624506
lissamine red w
4-hydroxy-3-[(4-sulfo-1-naphthalenyl) azo]-1-naphthalene sulfonic acid
4-hydroxy-3-[(4-sulpho-1-naphthyl)azo]naphthalene-1-sulphonic acid
c.i. chromotrope fb
4-hydroxy-3-[(4-sulfo-1-naphthalenyl)azo]-1-naphthalenesulfonic acid, 9ci
4-hydroxy-3-[(4-sulfonaphthalen-1-yl)diazenyl]naphthalene-1-sulfonic acid
SCHEMBL21274168
Q27269382
(e)-4-hydroxy-3-((4-sulfonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonic acid

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" In the present investigation, an attempt has been made to evaluate the toxic effects of a commonly used dye blend, tomato red on male Swiss albino mice."( Toxicity of tomato red, a popular food dye blend on male albino mice.
Chakravarty, G; Goyal, RP; Sharma, A; Sharma, S, 2008
)
0.35
"The objective of the present work was to evaluate the broadest toxic effect of some synthetic additives of colorants and/or flavors on different body organs and metabolic aspects in rats."( Toxic effects of some synthetic food colorants and/or flavor additives on male rats.
El-Wahab, HM; Moram, GS, 2013
)
0.39

Bioavailability

ExcerptReferenceRelevance
" The bioavailability of [14C]carmoisine, calculated from the blood-radioactivity curves after oral and iv administration, was less than 10%."( The metabolic disposition of 14C-labelled carmoisine in the rat after oral and intravenous administration.
Costa, LG; Galli, CL; Marinovich, M, 1982
)
0.26

Dosage Studied

ExcerptRelevanceReference
"05%, w/w) for 28 days prior to dosing with 14C-labelled colouring had no effect on the route of excretion or the time taken to eliminate the majority of the labelled dose."( Metabolic disposition of 14C-labelled carmoisine in the rat, mouse and guinea-pig.
Bex, C; Gaunt, IF; Phillips, JC; Walters, DG, 1987
)
0.27
" Analyses of the incubation medium by high-performance liquid chromatography (HPLC) attached to a radioactivity monitor (RAM) showed the same radioactivity profile as the urine and faeces of rats dosed with the same azodye (200 mg kg-1; 25 microCi)."( Application of a radioactivity detector to the analysis of 14C-carmoisine metabolites by ion-pair high-pressure liquid chromatography.
Costa, LG; Galli, CL; Marinovich, M; Tragni, E, 1984
)
0.27
" Animals were killed on day 19 of gestation, 2, 16, 64 h after dosing and blood, maternal tissues, amniotic fluids, placentae, fetal membranes and fetuses were analyzed for radioactivity."( Placental transfer and tissue localization of [14C]carmoisine in the pregnant rat.
Costa, LG; Galli, CL; Giavini, E; Marinovich, M, 1982
)
0.26
" Our data showed a significant increase in ALT, AST, ALP, urea, creatinine total protein and albumin in serum of rats dosed with tartrazine and carmoisine compared to control rats and these significant change were more apparent in high doses than low, GSH, SOD and Catalase were decreased and MDA increased in tissue homogenate in rats consumed high tartrazine and both doses of carmoisine."( Effect of food azo dyes tartrazine and carmoisine on biochemical parameters related to renal, hepatic function and oxidative stress biomarkers in young male rats.
Abd Elsttar, AH; Abdel Hameid, H; Amin, KA, 2010
)
0.36
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency67.74070.010039.53711,122.0200AID1469; AID1479
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (120)

TimeframeStudies, This Drug (%)All Drugs %
pre-199059 (49.17)18.7374
1990's3 (2.50)18.2507
2000's15 (12.50)29.6817
2010's29 (24.17)24.3611
2020's14 (11.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.44

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.44 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index4.48 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.44)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Trials2 (1.80%)5.53%
Reviews1 (5.00%)6.00%
Reviews2 (1.80%)6.00%
Case Studies0 (0.00%)4.05%
Case Studies3 (2.70%)4.05%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Other19 (95.00%)84.16%
Other104 (93.69%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]