quinazolines has been researched along with Epilepsy in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aleo, MD; Barton, HA; Di, L; Generaux, G; Howell, BA; Lakhani, VV; Nadanaciva, S; Qiu, L; Riccardi, K; Shoda, LKM; Siler, SQ; Watkins, PB; Yang, Y | 1 |
| Danzer, SC; Gross, C; MacLeod, MC; Tiwari, D; White, AR | 1 |
| Amini, E; Faraj, FL; Gholami, K; Golpich, M; Rothan, HA; Teoh, TC; Yusof, R | 1 |
| Burke, JF; Callaghan, BC; Esper, GJ; Hill, CE; Kerber, KA; Lin, CC; Magliocco, B; Skolarus, LE | 1 |
| Arcella, A; Cantore, G; Di Gennaro, G; Esposito, V; Eusebi, F; Fredholm, BB; Fucile, S; Limatola, C; Manfredi, M; Martinello, K; Mascia, A; Miledi, R; Piccari, V; Quarato, PP; Roseti, C; Simonato, M | 1 |
| Cao, SX; Chen, XJ; Chen, Z; Duan, S; Li, KX; Li, XM; Lu, YM; Luo, JH; Xu, ZH; Zhang, J; Zhang, JM; Zhu, JM | 1 |
| Emri, Z; Héja, L; Kardos, J; Lasztóczi, B; Nyikos, L; Simon, A; Szárics, E | 1 |
| Chapman, J; Maggio, N; Segal, M; Shavit, E | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B | 1 |
| Fukuyama, Y; Seki, T | 1 |
1 trial(s) available for quinazolines and Epilepsy
| Article | Year |
|---|---|
Quantitative systems toxicology (QST) reproduces species differences in PF-04895162 liver safety due to combined mitochondrial and bile acid toxicity.
Topics: Administration, Oral; Adolescent; Adult; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 11; Chemical and Drug Induced Liver Injury; Computer Simulation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epilepsy; Healthy Volunteers; HEK293 Cells; Hepatocytes; Humans; Inhibitory Concentration 50; Liver; Male; Middle Aged; Mitochondria; Models, Biological; Quinazolines; Rats; Species Specificity; Taurocholic Acid; Young Adult | 2019 |
9 other study(ies) available for quinazolines and Epilepsy
| Article | Year |
|---|---|
PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes.
Topics: Adenine; Animals; Cerebral Cortex; Class I Phosphatidylinositol 3-Kinases; Epilepsy; Female; Hippocampus; Male; Megalencephaly; Mice; Neurons; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Quinazolines; Seizures; Thiazoles | 2020 |
NMDA receptor antagonism with novel indolyl, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Hippocampus; Indoles; Male; Malondialdehyde; Molecular Docking Simulation; Protein Binding; Quinazolines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures | 2017 |
Claims data analyses unable to properly characterize the value of neurologists in epilepsy care.
Topics: Administrative Claims, Healthcare; Adult; Aged; Ambulatory Care; Anticonvulsants; Disease Management; Emergency Service, Hospital; Epilepsy; Female; Health Care Costs; Health Services; Hospitalization; Humans; Male; Middle Aged; Neurologists; Neurology; Neurosurgical Procedures; Propensity Score; Quinazolines; Severity of Illness Index; United States | 2019 |
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Topics: Adenosine; Adenosine Deaminase; Adult; Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurons; Oocytes; Purinergic P1 Receptor Antagonists; Pyramidal Tracts; Pyrimidines; Quinazolines; Rats; Receptors, GABA-A; Triazoles; Xanthines; Xenopus | 2008 |
Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy.
Topics: Action Potentials; Animals; Biophysics; Caveolin 1; Cell Line, Transformed; Disease Models, Animal; Down-Regulation; Electric Stimulation; Epilepsy; ErbB Receptors; Female; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Kv1.1 Potassium Channel; Male; Mice; Mice, Transgenic; Neuregulin-1; Neurons; Parvalbumins; Patch-Clamp Techniques; Pentylenetetrazole; Peptides; Pilocarpine; Potassium Channel Blockers; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-4; Signal Transduction; Tyrphostins | 2011 |
Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: involvement of a metabotropic glutamate receptor.
Topics: Age Factors; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cell Membrane; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; Male; Nerve Net; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Protein Subunits; Pyramidal Cells; Quinazolines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2006 |
Thrombin induces long-term potentiation of reactivity to afferent stimulation and facilitates epileptic seizures in rat hippocampal slices: toward understanding the functional consequences of cerebrovascular insults.
Topics: Afferent Pathways; Animals; Animals, Newborn; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Epilepsy; Glutamic Acid; Hemostatics; Hippocampus; Long-Term Potentiation; Male; Peptide Fragments; Potassium; Pyrroles; Quinazolines; Rats; Rats, Wistar; Receptor, PAR-1; Thrombin | 2008 |
Influence of CGS 15943 A (a nonxanthine adenosine antagonist) on the protection offered by a variety of antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Adenosine; Animals; Anticonvulsants; Disease Susceptibility; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Motor Activity; Quinazolines; Triazoles | 1991 |
[Clinical evaluation of 2-(beta-pyridyl-(2")-ethenyl)-3-(2'-methylphenyl)-quinazolinone-(4) (B169) in the treatment of epilepsy].
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethylenes; Female; Humans; Infant; Intellectual Disability; Male; Movement Disorders; Pyridines; Quinazolines; Sleep | 1971 |