Compounds > idazoxan
Page last updated: 2024-08-23

idazoxan and Epilepsy

idazoxan has been researched along with Epilepsy in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freiman, TM; Heinemeyer, J; Klar, M; Kukolja, J; Surges, R; van Velthoven, V; Zentner, J1
Hoffman, TJ; Razani-Boroujerdi, S; Savage, DD; Tso-Olivas, DY; Weiss, GK1
Alcalde, O; Bier, M; Farber, PR; Langer, J; Moghimi, R; Richkind, M; Shouse, MN; Szymusiak, R1
Butler, LS; Janumpalli, S; Limbird, LE; MacMillan, LB; McNamara, JO1
Dailey, JW; Jobe, PC; Steenbergen, JL; Yan, QS1
Chen, LS; McNamara, JO; Weingart, JB1
Bengzon, J; Brundin, P; Kokaia, M; Lindvall, O1

Other Studies

7 other study(ies) available for idazoxan and Epilepsy

ArticleYear
K(+)-evoked [(3)H]-norepinephrine release in human brain slices from epileptic and non-epileptic patients is differentially modulated by gabapentin and pinacidil.
    Neuroscience research, 2006, Volume: 55, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Amines; Anticonvulsants; Brimonidine Tartrate; Calcium Channel Blockers; Child; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Idazoxan; In Vitro Techniques; Male; Middle Aged; Norepinephrine; omega-Conotoxins; Pinacidil; Potassium; Quinoxalines; Time Factors; Tritium

2006
Decrease in locus coeruleus [3H]idazoxan binding site density in genetically epilepsy-prone (GEPR) rats.
    Brain research, 1993, Jan-15, Volume: 600, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Autoradiography; Brain; Dioxanes; Epilepsy; Female; Idazoxan; In Vitro Techniques; Locus Coeruleus; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Synapses; Up-Regulation

1993
The alpha 2-adrenoreceptor agonist clonidine suppresses seizures, whereas the alpha 2-adrenoreceptor antagonist idazoxan promotes seizures in amygdala-kindled kittens: a comparison of amygdala and pontine microinfusion effects.
    Epilepsia, 1996, Volume: 37, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amygdala; Animals; Cats; Clonidine; Dioxanes; Disease Susceptibility; Electrodes, Implanted; Epilepsy; Female; Functional Laterality; Idazoxan; Imidazoles; Kindling, Neurologic; Locus Coeruleus; Male; Microinjections; Norepinephrine; Seizures; Stereotaxic Techniques

1996
A point mutation (D79N) of the alpha2A adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Mar-15, Volume: 18, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Electrophysiology; Epilepsy; Idazoxan; Kindling, Neurologic; Mice; Mice, Mutant Strains; Norepinephrine; Point Mutation; Receptors, Adrenergic, alpha

1998
Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study.
    Brain research, 1998, Jan-12, Volume: 780, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Desipramine; Drug Interactions; Epilepsy; Female; Fluoxetine; Idazoxan; Methoxamine; Microinjections; Norepinephrine; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Superior Colliculi; Synaptic Transmission

1998
Biochemical and radiohistochemical analyses of alpha-2 adrenergic receptors in the kindling model of epilepsy.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Autoradiography; Brain; Cell Membrane; Clonidine; Dioxanes; Epilepsy; Idazoxan; Kindling, Neurologic; Male; Models, Neurological; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1990
Seizure suppression in kindling epilepsy by intrahippocampal locus coeruleus grafts: evidence for an alpha-2-adrenoreceptor mediated mechanism.
    Experimental brain research, 1990, Volume: 81, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Dioxanes; Dopamine beta-Hydroxylase; Epilepsy; Hippocampus; Hydroxydopamines; Idazoxan; Kindling, Neurologic; Locus Coeruleus; Male; Neurons; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Seizures; Transplantation, Heterotopic

1990