mecamylamine has been researched along with Epilepsy in 2 studies
Mecamylamine: A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Freitas, RL | 1 |
| de Oliveira, RC | 1 |
| de Carvalho, AD | 1 |
| Felippotti, TT | 1 |
| Bassi, GS | 1 |
| Elias-Filho, DH | 1 |
| Coimbra, NC | 1 |
| Scharfman, HE | 1 |
2 other studies available for mecamylamine and Epilepsy
| Article | Year |
|---|---|
Role of muscarinic and nicotinic cholinergic receptors in an experimental model of epilepsy-induced analgesia.
Topics: Animals; Atropine; Chlorides; Convulsants; Epilepsy; GABA Antagonists; Male; Mecamylamine; Muscarini | 2004 |
EPSPs of dentate gyrus granule cells during epileptiform bursts of dentate hilar "mossy" cells and area CA3 pyramidal cells in disinhibited rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Epilepsy; Evok | 1994 |