Page last updated: 2024-08-21

isoxazoles and Epilepsy

isoxazoles has been researched along with Epilepsy in 190 studies

Research

Studies (190)

TimeframeStudies, this research(%)All Research%
pre-199010 (5.26)18.7374
1990's30 (15.79)18.2507
2000's96 (50.53)29.6817
2010's54 (28.42)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takechi, K1
Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J2
Barary, MA; El-Yazbi, AF; Ibrahim, FA; Wagih, MM1
Collinet, A; Sammut, V1
Attri, SV; Kumar, B; Medhi, B; Modi, M; Patial, A; Saikia, B1
Juhos, V1
Ouyang, Y; Song, Z; Xiao, X; Zheng, W1
Imai, K; Inoue, K; Inoue, Y; Itoh, K; Kagawa, Y; Mishima, N; Takahashi, Y; Yamamoto, Y; Yazawa, R1
Lossius, MI; Markhus, R; Nakken, KO; Sætre, E1
Serrano-Castro, PJ; Villanueva, V1
Chen, G; Jiang, D; Kong, S; Pitre, A; Sun, Y; Wang, Y; Wu, Z1
Di Sabatino, F; Loiacono, G; Verrotti, A; Zaccara, G1
Giorgi, L; Patten, A; Segieth, J; Trinka, E1
Allaf, B; Biraben, A; Dupont, S; Lavernhe, G; Marquet, T1
Ando, H; Fujimura, A; Matsubara, S; Oi, A; Suzuki, M; Usui, R1
Cavanna, AE; Seri, S1
Matar, KM1
Fritsch, B; Gasior, M; Kaminski, RM; Reis, J; Rogawski, MA1
Auvin, S; Cross, JH; Giorgi, L; Patten, A1
Dahlin, M; Ohman, I; Wallander, KM1
Andersen, H; Lindstrøm, P; Nakken, KO1
Di Gennaro, G; Fattore, C; Femia, EA; Franco, V; Romigi, A; Vitrani, G1
Ackermann, AL; Frank, LA; May, ER; McEntee, MF1
Chen, TC; Chuang, YC; Dash, A; Huang, CW; Jou, SB; Kwan, SY1
Belova, YA; Rudakova, IG1
Bazil, CW; Jongeling, AC; Richins, RJ1
Coelho, R; Gaspar, R; Lopes, J; Macedo, G; Rodrigues, S; Silva, R1
Baulac, M; Hamer, H; Kockelmann, E; McMurray, R1
Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H1
Supuran, CT1
Aburashed, R; Bhatt, A; Farooq, MU; Kassab, MY; Moore, PW1
Bauer, J; Wellmer, J; Wellmer, S1
Balestri, P; Coppola, G; Curatolo, P; Franzoni, E; Grosso, S; Iannetti, P; Luchetti, A; Mangano, S; Operto, FF; Parisi, P; Pascotto, A; Pelliccia, A; Verrotti, A1
Rouvel-Tallec, A1
Legido, A; Valencia, I1
Kang, HC; Kim, HD; Lee, JS; Lee, YJ; Seo, JH1
Pellock, JM1
Dinapoli, L; Jandolo, B; Maschio, M; Saveriano, F1
Perry, CM; Yang, LP1
Carapella, CM; Dinapoli, L; Jandolo, B; Maschio, M; Pompili, A; Saveriano, F; Vidiri, A1
Appleton, RE; Kneen, R; Martland, TR; Tan, HJ1
Schulze-Bonhage, A1
Albani, F; Baruzzi, A; Candela, C; Contin, M; Mohamed, S; Riva, R1
Janszky, J1
Bramanti, P; Calabrò, RS; Ferlazzo, E; Italiano, D1
Fujita, Y; Hasegawa, M; Matsunaga, K; Murakami, K; Nabeshima, K; Nakai, S; Tomita, M; Yamakita, T1
Brodie, MJ; Kelly, K; Parker, P; Stephen, LJ; Wilson, EA1
Conant, KD; Dunne, IE; Linshaw, MA; Lyczkowski, DA; Paul, E; Pfeifer, HH; Thiele, EA1
Beniak, TE; Birnbaum, AK; Leppik, IE; Marino, SE; Walczak, TS; White, JR1
Li, JM; Li, Q; Peng, F; Yao, ZP; Zhou, D1
Avoli, M; Dzakpasu, R; Gonzalez-Sulser, A; Motamedi, GK; Vicini, S; Wang, J1
Alfirevic, A; Jorgensen, A; Marson, AG; Mirza, NS; Pirmohamed, M1
Chung, HJ; Eom, S; Eun, BL; Eun, SH; Kang, HC; Kim, DW; Kim, HD; Kim, JS; Lee, IK; Lee, JS; Lee, YM; Moon, HK; Suh, ES1
Bartolini, E; Bell, GS; Catarino, CB; Duncan, JS; Sander, JW; Yuen, AW1
Cincotta, M; Tramacere, L; Zaccara, G1
Muñana, KR; Olby, NJ; Schwartz, M1
Holder, JL; Wilfong, AA1
Kim, DW; Park, KS; Yoo, MW1
Gekht, AB; Mil'chakova, LE1
Ahn, JO; Chae, JS; Chung, JY; Hwang, CY; Kim, TH; Lee, SY; Seo, KW; Youn, HY1
Ben-Menachem, E; Brodie, MJ; Chouette, I; Giorgi, L1
Inoue, Y; Terada, K1
Campistol, J; Darling, A; Perez-Duenas, B; Poo, P1
Hayashi, K; Jo, K; Katsumori, H; Nagafuchi, H; Oguni, H; Osawa, M; Saito, Y; Yanagaki, S1
Kurokawa, T1
Sirven, JI1
Alldredge, BK; Chen, JT; Garcia, PA1
Bergin, AM; Connolly, M1
Haginoya, K; Hirose, M; Iinuma, K; Yokoyama, H1
Johannessen, SI; Perucca, E1
Doi, T; Tokumaru, J; Ueda, Y; Willmore, LJ1
Go, T1
Fukuoka, N; Kimura, M; Morita, S; Tsukamoto, T; Uno, J2
Hansen, SL; Sánchez, C; Sperling, BB1
Iyo, M; Kobayashi, K; Noda, S; Ozawa, K1
Fujiwara, T; Iinuma, K1
Dubinsky, S; Newmark, ME1
Hasegawa, H1
Anthony, S; James, SP; Miller, GS; Montouris, G; Uthman, BM1
Conry, JA1
Larsson, OM; Sarup, A; Schousboe, A; White, HS1
Garnett, WR; Levy, RH; Pan, WJ; Ragueneau-Majlessi, I; Rosenfeld, W; Schmerler, M; Shah, J1
Yagi, K1
Seino, M1
Miura, H3
Haginoya, K; Iinuma, K1
Kumagai, N; Maezawa, M; Seki, T1
Aikawa, H; Yamauchi, T1
Ohtahara, S; Yamatogi, Y2
Willmore, LJ2
Brodie, MJ1
Bergen, D; Garnett, W; Grundy, JS; Levy, RH; Mather, G; Ragueneau-Majlessi, I; Rosenfeld, W; Shah, J1
Wilfong, AA1
Brodie, MJ; Levy, RH; Pan, WJ; Ragueneau-Majlessi, I; Shah, J; Smith, DF1
Aldridge, J; Kim, HL; Rho, JM1
Biton, V1
Brodie, M; Grundy, JS; Levy, RH; Ragueneau-Majlessi, I; Shah, J; Smith, D1
Ohtahara, S1
Zareba, G1
Leppik, IE4
Tisdell, J; Tosches, WA1
Hamano, S; Imai, K; Motohashi, S; Sato, M; Yoshida, T1
Borowicz, KK; Czuczwar, SJ; Luszczki, JJ; Patsalos, PN; Ratnaraj, N; Sobieszek, G1
Arzimanoglou, A; Rahbani, A1
Feuerstein, TJ; Stefan, H1
Johannessen, SI; Tomson, T1
Fukushima, K; Seino, M1
Arinami, T; Hasegawa, M; Kamoda, T; Kanemoto, K; Kanemoto, N1
Doi, T; Kato, T; Nikaido, K; Takayama, R1
Goto, S; Ishitsu, T; Murata, T; Nakada, N; Nakagawa, K; Seo, T; Ueda, N1
Matsuura, M1
Brodie, M; Sills, G1
Rambeck, B; Tipold, A; von Klopmann, T1
Michael, CT; Starr, JL1
Davenport, RD; Patel, NC1
Wroe, S1
Thöne, J; Wiemann, M1
Bauer, J; Bös, M1
Akechi, T; Azuma, H; Furukawa, TA; Hattori, M; Masayasu, T; Negi, A1
Hwang, YH; Kwon, SH; Lee, BI; Lee, HW; Park, SP; Suh, CK1
Kang, HC; Kim, HD; Ko, TS; Lee, HS; You, SJ1
Appleton, RE; Macleod, S1
Conry, JA; Pellock, JM; Shinnar, S1
Leniger, T; Splettstösser, F; Thöne, J; Wiemann, M1
Kaleyias, J; Kothare, SV1
Berent, S; Donofrio, PD; Sackellares, JC; Sakmar, E; Wagner, JG1
Kakegawa, N; Seino, M1
Dam, M; Jensen, I; Petersen, HR1
Hori, M; Ito, T; Masuda, Y; Shimizu, M; Yoshida, K1
Peters, DH; Sorkin, EM1
Pimentel, J; Pinto, F1
Patsalos, PN; Sander, JW1
Hashimoto, Y; Hori, R; Odani, A; Okuno, T; Tanigawara, Y; Yasuhara, M1
Hirai, K; Kumagai, N; Seki, T; Takuma, Y; Yamada, T1
Shields, WD1
Fromm, G; Homan, RW; Leppik, IE; Lesser, RP; Oommen, KJ; Penry, JK; Sackellares, JC; Smith, DB; Wallace, JD; Willmore, LJ1
Kito, M; Maehara, M; Watanabe, K1
Ito, T; Kurokawa, M; Masuda, Y; Shimizu, M; Uno, H1
Akita, M; Hasegawa, M; Hasegawa, T; Nabeshima, T; Shinoda, M1
Chadwick, DW; Kadir, ZA; Marson, AG1
Chadwick, DW; Kadir, Z; Marson, T1
Amano, Y; Egawa, I; Kaneko, S; Kondo, T1
Grippo, J1
Eguchi, T; Fujita, N; Kishi, T; Ueda, K1
Dejima, S; Hara, T; Maeoka, Y; Takeshita, K1
Kato, H; Matsuishi, T; Ohnishi, A; Satoi, M; Shimizu, T; Togo, A; Wada, N; Yamashita, Y1
Chadwick, DW; Hutton, JL; Kadir, ZA; Marson, AG1
Cho, K; Iinuma, K; Kajii, N; Minami, T; Tachi, N1
Perucca, E1
Kohsaka, M; Koyama, T; Miyamoto, T1
Vajda, FJ1
Hayakawa, F; Ishihara, N; Kato, T; Kuno, K; Okumura, A; Watanabe, K1
Hiramatsu, M; Komatsu, M; Willmore, LJ1
Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M3
Jain, KK1
Fatope, MO1
Biederman, TS; McAuley, JW; Moore, JL; Smith, JC1
Fujioka, T; Hakui, T; Hanada, K; Kondou, T; Mine, M; Seike, E; Sitaya, M; Tounou, S1
Ishii, M; Isobe, K; Itoh, S; Kawada, K; Kusaka, T1
Wheless, JW1
Glauser, TA; Pellock, JM1
Amano, S; Ihara, N; Miura, Y; Torii, R1
Seino, M; Yagi, K1
Fukuchi, H; Harada, Y; Kimura, M; Kimura, Y; Kitaura, T; Miyake, K; Tanaka, N1
Hara, M; Hashimoto, R; Hirai, K; Kimiya, S; Kumagai, N; Seki, T; Suzuki, N; Takuma, Y; Yamada, T; Yamawaki, H1
Ito, T; Miyazaki, H; Seino, M1
Fujimoto, Y; Ikoma, R; Shimizu, A; Shimizu, T1
Hasegawa, H; Wada, Y; Yamaguchi, N1
Hasegawa, H; Okuda, H; Wada, Y; Yamaguchi, N1
Depaulis, A; Marescaux, C; Snead, OC; Vergnes, M1
Falch, E; Krogsgaard-Larsen, P; Larsson, OM; Schousboe, A1
Löscher, W1
Kawasaki, T; Shimizu, A; Tanaka, M; Yamada, Y; Yamamoto, J1
Hammond, EJ; McLean, JR; Perchalski, RJ; Wilder, BJ1
Buchanan, RA; Friel, PN; Levy, RH; McLean, JR; Ojemann, LM; Shastri, RA; Wilensky, AJ1

Reviews

61 review(s) available for isoxazoles and Epilepsy

ArticleYear
[Neurobehavioral Comorbidities in Pentylenetetrazol-kindled Mice and Role of the α4β2 Nicotinic Acetylcholine Receptor].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:11

    Topics: Animals; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Down-Regulation; Epilepsy; Isoxazoles; Kindling, Neurologic; Membrane Proteins; Mental Disorders; Mice; Nerve Tissue Proteins; Pentylenetetrazole; Piriform Cortex; Psychomotor Performance; Pyrrolidines; Quality of Life; Receptors, Nicotinic; Seizures; Social Behavior

2019
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 06-29, Volume: 6

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide

2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 12-15, Volume: 12

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide

2017
[The role of zonisamide in the treatment of women with epilepsy].
    Ideggyogyaszati szemle, 2016, Nov-30, Volume: 69, Issue:11-12

    Topics: Anticonvulsants; Epilepsy; Female; Humans; Isoxazoles; Zonisamide

2016
[Epilepsy in the elderly].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2013, Mar-05, Volume: 133, Issue:5

    Topics: Age Factors; Aged; Aging; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Piracetam; Quality of Life; Seizures; Triazines; Zonisamide

2013
[Zonisamide in the epilepsy treatment: a literature review from add-on therapy to monotherapy].
    Revista de neurologia, 2013, Apr-16, Volume: 56, Issue:8

    Topics: Adult; Animals; Anorexia; Anticonvulsants; Antioxidants; Carbonic Anhydrase Inhibitors; Child; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Europe; Fatigue; Headache; Humans; Ion Channels; Isoxazoles; Multicenter Studies as Topic; Neurotransmitter Agents; Randomized Controlled Trials as Topic; United States; Zonisamide

2013
The adverse event profile of zonisamide: a meta-analysis.
    Acta neurologica Scandinavica, 2013, Volume: 128, Issue:5

    Topics: Anticonvulsants; Clinical Trials as Topic; Databases, Factual; Epilepsy; Humans; Isoxazoles; Zonisamide

2013
Zonisamide in the management of epilepsy in the elderly.
    Clinical interventions in aging, 2015, Volume: 10

    Topics: Aged; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Zonisamide

2015
[New possibilities of monotherapy of symptomatic and cryptogenic partial epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Isoxazoles; Zonisamide

2015
Therapeutic role of zonisamide in neuropsychiatric disorders.
    Mini reviews in medicinal chemistry, 2008, Volume: 8, Issue:10

    Topics: Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Psychotic Disorders; Retrospective Studies; Zonisamide

2008
[Role of monotherapy with new antiepileptic drugs in the treatment of childhood epilepsy].
    Medicina, 2009, Volume: 69, Issue:1 Pt 1

    Topics: Anticonvulsants; Carbamazepine; Child; Drug Administration Schedule; Epilepsy; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Piracetam; Topiramate; Triazines; Zonisamide

2009
New pharmacotherapies for pediatric seizures.
    Pediatric annals, 2004, Volume: 33, Issue:6

    Topics: Adolescent; Amines; Animals; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Pediatrics; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

2004
Zonisamide in the treatment of epilepsy.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:1

    Topics: Adult; Animals; Anticonvulsants; Clinical Trials as Topic; Compassionate Use Trials; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Epilepsy; Europe; Humans; Isoxazoles; Randomized Controlled Trials as Topic; Syndrome; Treatment Outcome; Zonisamide

2010
[Role of zonisamid in treating epilepsy, Parkinson disorders and other neurological diseases].
    Ideggyogyaszati szemle, 2009, Nov-30, Volume: 62, Issue:11-12

    Topics: Anticonvulsants; Bipolar Disorder; Calcium Channels, T-Type; Cholinergic Agents; Dopamine Agents; Dyskinesias; Epilepsy; Excitatory Amino Acid Agents; Feeding and Eating Disorders; GABA Agents; Humans; Isoxazoles; Migraine Disorders; Nerve Tissue Proteins; Nervous System Diseases; Neuroprotective Agents; Obesity; Parkinson Disease; Randomized Controlled Trials as Topic; Sodium Channels; Treatment Outcome; Voltage-Gated Sodium Channel beta-2 Subunit; Zonisamide

2009
Drug safety evaluation of zonisamide for the treatment of epilepsy.
    Expert opinion on drug safety, 2011, Volume: 10, Issue:4

    Topics: Animals; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Humans; Isoxazoles; Kidney Calculi; Mental Disorders; Randomized Controlled Trials as Topic; Zonisamide

2011
Zonisamide in the treatment of epilepsy.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:16

    Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Calcium Channels, T-Type; Epilepsy; Humans; Isoxazoles; Sodium Channel Blockers; Zonisamide

2011
[New drugs in the treatment of adult patients with refractery epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:10 Pt 2

    Topics: Adult; Anticonvulsants; Dibenzazepines; Epilepsy; Humans; Isoxazoles; Zonisamide

2011
Zonisamide: its pharmacology, efficacy and safety in clinical trials.
    Acta neurologica Scandinavica. Supplementum, 2012, Issue:194

    Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Dose-Response Relationship, Drug; Epilepsy; Humans; Isoxazoles; Treatment Outcome; Zonisamide

2012
[Medication-related oculogyric crises: a description of four cases and a review of the literature].
    Revista de neurologia, 2013, Feb-01, Volume: 56, Issue:3

    Topics: Adolescent; Anticonvulsants; Antipsychotic Agents; Aripiprazole; Child; Child Behavior Disorders; Child, Preschool; Dopamine; Dopamine Antagonists; Down Syndrome; Dyskinesia, Drug-Induced; Dystonic Disorders; Electroencephalography; Epilepsy; Female; Fragile X Syndrome; Humans; Intellectual Disability; Isoxazoles; Male; Methotrimeprazine; Ocular Motility Disorders; Paliperidone Palmitate; Piperazines; Pyrimidines; Quinolones; Risperidone; Substance Withdrawal Syndrome; Translocation, Genetic; Valproic Acid

2013
Antiepileptic drug therapy for adults: when to initiate and how to choose.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:12

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Recurrence; Risk Factors; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2002
New antiepileptic drug therapies.
    Neurologic clinics, 2002, Volume: 20, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2002
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
    Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5 Suppl 1

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2003
[Clinical guidelines for treatment of epilepsy in children].
    No to hattatsu = Brain and development, 2004, Volume: 36, Issue:2

    Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cosyntropin; Electroencephalography; Epilepsy; Frontal Lobe; Humans; Isoxazoles; Life Style; Magnetic Resonance Imaging; Phenytoin; Practice Guidelines as Topic; Temporal Lobe; Valproic Acid; Zonisamide

2004
Pharmacologic treatment of the catastrophic epilepsies.
    Epilepsia, 2004, Volume: 45 Suppl 5

    Topics: Anticonvulsants; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Fructose; Humans; Infant; Isoxazoles; Lamotrigine; Spasms, Infantile; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

2004
Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy.
    European journal of pharmacology, 2004, Oct-01, Volume: 500, Issue:1-3

    Topics: Animals; Anticonvulsants; Carrier Proteins; Epilepsy; GABA Plasma Membrane Transport Proteins; Humans; Isoxazoles; Membrane Transport Modulators

2004
Review of zonisamide development in Japan.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Japan; Product Surveillance, Postmarketing; Zonisamide

2004
Zonisamide overview of the United States experience.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Anticonvulsants; Epilepsy; Humans; Isoxazoles; Retrospective Studies; United States; Zonisamide

2004
Zonisamide: newer antiepileptic agent with multiple mechanisms of action.
    Expert review of neurotherapeutics, 2004, Volume: 4, Issue:6

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Epilepsy; Follow-Up Studies; History, 20th Century; History, 21st Century; Humans; Isoxazoles; Neuroprotective Agents; Zonisamide

2004
Antiepileptic drugs and neuroprotection: current status and future roles.
    Epilepsy & behavior : E&B, 2005, Volume: 7 Suppl 3

    Topics: Animals; Anticonvulsants; Brain; Epilepsy; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Neuroprotective Agents; Piracetam; Seizures; Topiramate; Triazines; Zonisamide

2005
Zonisamide in the management of epilepsy--Japanese experience.
    Epilepsy research, 2006, Volume: 68 Suppl 2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Japan; Zonisamide

2006
Zonisamide: review of its use in epilepsy therapy.
    Drugs of today (Barcelona, Spain : 1998), 2005, Volume: 41, Issue:9

    Topics: Animals; Anticonvulsants; Biological Availability; Child; Child, Preschool; Drug Interactions; Epilepsy; Half-Life; Humans; Infant; Isoxazoles; Migraine Disorders; Pain; Parkinson Disease; Randomized Controlled Trials as Topic; Tissue Distribution; Zonisamide

2005
Practical prescribing and long-term efficacy and safety of zonisamide.
    Epilepsy research, 2006, Volume: 68 Suppl 2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Zonisamide

2006
Zonisamide for the treatment of epilepsy.
    Expert review of neurotherapeutics, 2006, Volume: 6, Issue:9

    Topics: Anticonvulsants; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Practice Patterns, Physicians'; Treatment Outcome; Zonisamide

2006
Novel anticonvulsant drugs.
    Pharmacology & therapeutics, 2007, Volume: 113, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2007
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
    Clinical pharmacokinetics, 2006, Volume: 45, Issue:11

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2006
[Newer antiepileptic drugs].
    No to shinkei = Brain and nerve, 2007, Volume: 59, Issue:2

    Topics: Amines; Animals; Anti-Anxiety Agents; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drug Interactions; Epilepsy; Felbamate; Fructose; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Neuroprotective Agents; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Sodium Channel Blockers; Topiramate; Triazines; Zonisamide

2007
Pharmacokinetics and drug interactions with zonisamide.
    Epilepsia, 2007, Volume: 48, Issue:3

    Topics: Anticonvulsants; Contraceptives, Oral; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Isoxazoles; Treatment Outcome; Zonisamide

2007
The new antiepileptic drugs.
    Archives of disease in childhood. Education and practice edition, 2007, Volume: 92, Issue:6

    Topics: Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsies, Partial; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Topiramate; Triazines; Vigabatrin; Zonisamide

2007
Zonisamide: review of pharmacology, clinical efficacy, tolerability, and safety.
    Expert opinion on drug metabolism & toxicology, 2008, Volume: 4, Issue:4

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Brain Diseases; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Mental Disorders; Treatment Outcome; Zonisamide

2008
Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy.
    Drugs, 1993, Volume: 45, Issue:5

    Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Zonisamide

1993
[New antiepileptic medications].
    Acta medica portuguesa, 1995, Volume: 8, Issue:1

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Triazines; Vigabatrin; Zonisamide

1995
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
    Drug safety, 1994, Volume: 11, Issue:1

    Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

1994
Antiepileptic drugs in development: prospects for the near future.
    Epilepsia, 1994, Volume: 35 Suppl 4

    Topics: Acetates; Adult; Amines; Aminocaproates; Animals; Anticonvulsants; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Drug Design; Drugs, Investigational; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Vigabatrin; Zonisamide

1994
Investigational antiepileptic drugs for the treatment of childhood seizure disorders: a review of efficacy and safety.
    Epilepsia, 1994, Volume: 35 Suppl 2

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child; Clinical Trials as Topic; Clobazam; Drug Design; Drug Evaluation, Preclinical; Drugs, Investigational; Epilepsy; Felbamate; Humans; Isoxazoles; Lamotrigine; Phenylcarbamates; Propylene Glycols; Triazines; Zonisamide

1994
[Research and development of zonisamide, a new type of antiepileptic drug].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1996, Volume: 116, Issue:7

    Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Dogs; Drug Design; Electroencephalography; Epilepsy; Humans; Isoxazoles; Mice; Rabbits; Rats; Structure-Activity Relationship; Zonisamide

1996
New antiepileptic drugs: a systematic review of their efficacy and tolerability.
    BMJ (Clinical research ed.), 1996, Nov-09, Volume: 313, Issue:7066

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

1996
Clinical administration of new antiepileptic drugs: an overview of safety and efficacy.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Odds Ratio; Placebos; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

1996
[Treatment of the epilepsy: new drugs].
    Revista de neurologia, 1996, Volume: 24, Issue:135

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Topiramate; Triazines; Vigabatrin; Zonisamide

1996
The new antiepileptic drugs: a systematic review of their efficacy and tolerability.
    Epilepsia, 1997, Volume: 38, Issue:8

    Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide

1997
Zonisamide.
    Epilepsia, 1999, Volume: 40 Suppl 5

    Topics: Adult; Animals; Anticonvulsants; Clinical Trials as Topic; Disease Models, Animal; Drug Administration Schedule; Epilepsies, Myoclonic; Epilepsy; Humans; Isoxazoles; Treatment Outcome; Zonisamide

1999
The clinical pharmacokinetics of the new antiepileptic drugs.
    Epilepsia, 1999, Volume: 40 Suppl 9

    Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide

1999
New antiepileptic drugs.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2000
An assessment of zonisamide as an anti-epileptic drug.
    Expert opinion on pharmacotherapy, 2000, Volume: 1, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy; Female; Humans; Isoxazoles; Middle Aged; Pregnancy; Zonisamide

2000
Soretolide (Laboratoires Biocodex).
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:6

    Topics: Animals; Anticonvulsants; Contraindications; Epilepsy; Humans; Isoxazoles; Structure-Activity Relationship

2001
Newer therapies in the drug treatment of epilepsy.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Drug Interactions; Epilepsy; Humans; Isoxazoles; Levetiracetam; Oxcarbazepine; Piracetam; Zonisamide

2002
Three new drugs for epilepsy: levetiracetam, oxcarbazepine, and zonisamide.
    Journal of child neurology, 2002, Volume: 17 Suppl 1

    Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Levetiracetam; Oxcarbazepine; Piracetam; Treatment Outcome; Zonisamide

2002
Using the new antiepilepsy drugs in children.
    Journal of child neurology, 2002, Volume: 17 Suppl 1

    Topics: Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Humans; Isoxazoles; Levetiracetam; Oxcarbazepine; Piracetam; Treatment Outcome; Zonisamide

2002
Zonisamide in pediatric epilepsy: review of the Japanese experience.
    Journal of child neurology, 2002, Volume: 17, Issue:2

    Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Japan; Treatment Outcome; Zonisamide

2002
Zonisamide.
    Epilepsy research. Supplement, 1991, Volume: 3

    Topics: Animals; Anticonvulsants; Brain; Drugs, Investigational; Electroencephalography; Epilepsy; Evoked Potentials; Humans; Isoxazoles; Zonisamide

1991
GABA uptake inhibitors: relevance to antiepileptic drug research.
    Epilepsy research, 1987, Volume: 1, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Epilepsy; gamma-Aminobutyric Acid; Isoxazoles; Molecular Conformation; Neurotransmitter Uptake Inhibitors; Oxazoles

1987
Neuropharmacology of zonisamide, a new antiepileptic drug.
    General pharmacology, 1987, Volume: 18, Issue:3

    Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Carbonic Anhydrase Inhibitors; Drug Interactions; Epilepsy; Isoxazoles; Kinetics; Oxazoles; Zonisamide

1987

Trials

25 trial(s) available for isoxazoles and Epilepsy

ArticleYear
Zonisamide in children and young adults with refractory epilepsy: an open label, multicenter Italian study.
    Epilepsy research, 2009, Volume: 83, Issue:2-3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Tolerance; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Isoxazoles; Italy; Magnetic Resonance Imaging; Male; Neurologic Examination; Statistics, Nonparametric; Young Adult; Zonisamide

2009
Efficacy and tolerability of adjunctive therapy with zonisamide in childhood intractable epilepsy.
    Brain & development, 2010, Volume: 32, Issue:3

    Topics: Adolescent; Anticonvulsants; Chemotherapy, Adjuvant; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Isoxazoles; Male; Retrospective Studies; Severity of Illness Index; Spasms, Infantile; Treatment Outcome; Zonisamide

2010
Comparative trial of low- and high-dose zonisamide as monotherapy for childhood epilepsy.
    Seizure, 2011, Volume: 20, Issue:7

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Humans; Isoxazoles; Male; Treatment Outcome; Zonisamide

2011
Zonisamide monotherapy for idiopathic epilepsy in dogs.
    New Zealand veterinary journal, 2012, Volume: 60, Issue:6

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Isoxazoles; Zonisamide

2012
Zonisamide monotherapy in a multi-group clinic.
    Seizure, 2004, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Anticonvulsants; Drug Administration Schedule; Epilepsy; Female; Humans; Isoxazoles; Male; Patient Care Team; Zonisamide

2004
Safety of 25- and 50-mg capsules in the initiation of zonisamide therapy in patients with epilepsy: an uncontrolled, open-label study.
    Current medical research and opinion, 2004, Volume: 20, Issue:6

    Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Isoxazoles; Male; United States; Zonisamide

2004
Lack of a clinically significant effect of zonisamide on phenytoin steady-state pharmacokinetics in patients with epilepsy.
    Journal of clinical pharmacology, 2004, Volume: 44, Issue:11

    Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Drug Interactions; Epilepsy; Female; Humans; Isoxazoles; Male; Metabolic Clearance Rate; Middle Aged; Phenytoin; Zonisamide

2004
Zonisamide monotherapy with once-daily dosing in children with cryptogenic localization-related epilepsies: clinical effects and pharmacokinetic studies.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Isoxazoles; Male; Treatment Outcome; Zonisamide

2004
Clinical efficacy of zonisamide in childhood epilepsy after long-term treatment: a postmarketing, multi-institutional survey.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Disability Evaluation; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Isoxazoles; Male; Product Surveillance, Postmarketing; Severity of Illness Index; Time; Treatment Outcome; Zonisamide

2004
Effects of zonisamide monotherapy in children with epilepsy.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Electroencephalography; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Severity of Illness Index; Treatment Outcome; Tuberous Sclerosis; Zonisamide

2004
Efficacy of zonisamide: our experience.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Product Surveillance, Postmarketing; Prospective Studies; Retrospective Studies; Treatment Outcome; Zonisamide

2004
Zonisamide clinical trials: European experience.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Adult; Anticonvulsants; Demography; Double-Blind Method; Epilepsy; Europe; Female; Humans; Isoxazoles; Male; Middle Aged; Treatment Outcome; Zonisamide

2004
Carbamazepine pharmacokinetics are not affected by zonisamide: in vitro mechanistic study and in vivo clinical study in epileptic patients.
    Epilepsy research, 2004, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Area Under Curve; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Epilepsy; Female; Humans; In Vitro Techniques; Isoenzymes; Isoxazoles; Kinetics; Male; Microsomes, Liver; Middle Aged; Tissue Distribution; Zonisamide

2004
Lack of clinically significant pharmacokinetic interactions between zonisamide and lamotrigine at steady state in patients with epilepsy.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:2

    Topics: Adult; Area Under Curve; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Lamotrigine; Liver; Male; Time Factors; Triazines; Zonisamide

2005
Prospective study of zonisamide therapy for refractory idiopathic epilepsy in dogs.
    The Journal of small animal practice, 2007, Volume: 48, Issue:3

    Topics: Administration, Oral; Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Isoxazoles; Prospective Studies; Treatment Outcome; Zonisamide

2007
Zonisamide and renal calculi in patients with epilepsy: how big an issue?
    Current medical research and opinion, 2007, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Child; Double-Blind Method; Epilepsy; Female; Fructose; Humans; Isoxazoles; Kidney Calculi; Male; Middle Aged; Placebos; Product Surveillance, Postmarketing; Topiramate; Ultrasonography; Zonisamide

2007
[Anticonvulsant treatment with zonisamide added to topiramate. A preliminary treatment analysis in 19 patients].
    Der Nervenarzt, 2007, Volume: 78, Issue:12

    Topics: Adult; Aged; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Isoxazoles; Male; Middle Aged; Pilot Projects; Topiramate; Treatment Outcome; Zonisamide

2007
Long-term cognitive and mood effects of zonisamide monotherapy in epilepsy patients.
    Epilepsy & behavior : E&B, 2008, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Affect; Anticonvulsants; Cognition; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Female; Humans; Isoxazoles; Longitudinal Studies; Male; Neuropsychological Tests; Prospective Studies; Zonisamide

2008
Open-label, long-term safety study of zonisamide administered to children and adolescents with epilepsy.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Drug Tolerance; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Female; Humans; Isoxazoles; Male; Pancreatitis; Seizures; Severity of Illness Index; Sweating; Time Factors; Treatment Outcome; Vertigo; Zonisamide

2009
THIP: a single-blind controlled trial in patients with epilepsy.
    Acta neurologica Scandinavica, 1983, Volume: 67, Issue:2

    Topics: Adult; Anticonvulsants; Drug Evaluation; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Oxazoles

1983
Developmental and therapeutic pharmacology of antiepileptic drugs.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Infant; Isoxazoles; Male; Phenytoin; Prospective Studies; Valproic Acid; Zonisamide

1993
Efficacy and safety of zonisamide: results of a multicenter study.
    Epilepsy research, 1993, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Zonisamide

1993
Long-term effects of zonisamide in the treatment of epilepsy in children with intellectual disability.
    Journal of intellectual disability research : JIDR, 1998, Volume: 42 Suppl 1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Intellectual Disability; Isoxazoles; Male; Time Factors; Zonisamide

1998
Predictive value of acetylcholine stimulation testing for oligohidrosis caused by zonisamide.
    Pediatric neurology, 2000, Volume: 23, Issue:1

    Topics: Acetylcholine; Anticonvulsants; Child; Child, Preschool; Cholinergic Agents; Epilepsy; False Positive Reactions; Female; Fever; Humans; Hypohidrosis; Isoxazoles; Male; Predictive Value of Tests; Prognosis; Sensitivity and Specificity; Sweating; Treatment Outcome; Zonisamide

2000
Developmental and therapeutic pharmacology of antiepileptic drugs.
    Epilepsia, 2000, Volume: 41 Suppl 9

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Administration Schedule; Drug Industry; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Half-Life; Humans; Infant; Intestinal Absorption; Isoxazoles; Lamotrigine; Prospective Studies; Treatment Outcome; Triazines; Valproic Acid; Zonisamide

2000

Other Studies

104 other study(ies) available for isoxazoles and Epilepsy

ArticleYear
Chromatographic determination of zonisamide, topiramate and sulpiride in plasma by a fluorescent 'turn-on' chemosensor.
    Bioanalysis, 2017, Volume: 9, Issue:14

    Topics: Adult; Anticonvulsants; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Epilepsy; Female; Fructose; Humans; Hydrogen-Ion Concentration; Isoxazoles; Limit of Detection; Linear Models; Male; Spectrometry, Fluorescence; Sulpiride; Time Factors; Topiramate; Water; Zonisamide

2017
Suspected zonisamide-related anticonvulsant hypersensitivity syndrome in a cat.
    Journal of the American Veterinary Medical Association, 2017, Dec-15, Volume: 251, Issue:12

    Topics: Animals; Anticonvulsants; Cat Diseases; Cats; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Isoxazoles; Male; Seizures; Zonisamide

2017
A mechanistic approach to explore the neuroprotective potential of zonisamide in seizures.
    Inflammopharmacology, 2018, Volume: 26, Issue:4

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Free Radicals; Inflammation; Isoxazoles; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Seizures; Zonisamide

2018
[Progress in synaptic mechanism in epileptogenesis].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Jan-28, Volume: 43, Issue:1

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Isoxazoles; N-Ethylmaleimide-Sensitive Proteins; Nerve Tissue Proteins; Qa-SNARE Proteins; Recurrence; Synapses; Synaptic Vesicles; Zonisamide

2018
Risk factors for hyperammonemia in pediatric patients with epilepsy.
    Epilepsia, 2013, Volume: 54, Issue:6

    Topics: Acetazolamide; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Hyperammonemia; Infant; Isoxazoles; Male; Phenobarbital; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Topiramate; Valproic Acid; Zonisamide

2013
Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABAA receptors.
    Molecular brain, 2013, May-01, Volume: 6

    Topics: Animals; Benzothiadiazines; Cells, Cultured; Epilepsy; Female; gamma-Aminobutyric Acid; HEK293 Cells; Hippocampus; Humans; Inhibitory Postsynaptic Potentials; Ion Channel Gating; Isoxazoles; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Synapses; Synaptic Transmission

2013
Safety and tolerability of zonisamide in elderly patients with epilepsy.
    Acta neurologica Scandinavica, 2013, Volume: 128, Issue:6

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Databases, Bibliographic; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Isoxazoles; Male; Treatment Outcome; Zonisamide

2013
Management and monitoring of patients treated with zonisamide: the OZONE study.
    Epileptic disorders : international epilepsy journal with videotape, 2013, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Data Collection; Data Interpretation, Statistical; Drug Resistance; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Longitudinal Studies; Male; Middle Aged; Monitoring, Physiologic; Quality of Life; Seizures; Treatment Outcome; Young Adult; Zonisamide

2013
Two nursing mothers treated with zonisamide: Should breast-feeding be avoided?
    The journal of obstetrics and gynaecology research, 2014, Volume: 40, Issue:1

    Topics: Adult; Anticonvulsants; Biological Availability; Breast Feeding; Child Development; Epilepsy; Female; Fetal Blood; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Isoxazoles; Lactation; Male; Milk, Human; Zonisamide

2014
Psychiatric adverse effects of zonisamide in patients with epilepsy and mental disorder comorbidities.
    Epilepsy & behavior : E&B, 2013, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Electroencephalography; Epilepsy; Female; Humans; Isoxazoles; Longitudinal Studies; Magnetic Resonance Imaging; Male; Mental Disorders; Middle Aged; Psychotic Disorders; Zonisamide

2013
Impact of pregnancy on zonisamide pharmacokinetics in rabbits.
    BioMed research international, 2013, Volume: 2013

    Topics: Administration, Oral; Animals; Anticonvulsants; Epilepsy; Female; Humans; Isoxazoles; Pregnancy; Rabbits; Tandem Mass Spectrometry; Zonisamide

2013
Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Apr-23, Volume: 34, Issue:17

    Topics: Amygdala; Animals; Epilepsy; Excitatory Amino Acid Agonists; GluK2 Kainate Receptor; Hippocampus; Isoxazoles; Mice; Mice, Knockout; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Seizures

2014
Safety and tolerability of zonisamide in paediatric patients with epilepsy.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2014, Volume: 18, Issue:6

    Topics: Anticonvulsants; Child; Child, Preschool; Controlled Clinical Trials as Topic; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Isoxazoles; Male; Pediatrics; Treatment Outcome; Zonisamide

2014
Zonisamide: pharmacokinetics, efficacy, and adverse events in children with epilepsy.
    Neuropediatrics, 2014, Volume: 45, Issue:6

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Male; Metabolic Clearance Rate; Retrospective Studies; Sex Factors; Treatment Outcome; Zonisamide

2014
Retention rate of zonisamide in intractable epilepsy.
    Acta neurologica Scandinavica, 2015, Volume: 131, Issue:5

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Denmark; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Male; Middle Aged; Norway; Patient Dropouts; Piracetam; Quality of Life; Sweden; Treatment Outcome; Triazines; Young Adult; Zonisamide

2015
Erythema multiforme associated with zonisamide in a dog.
    Veterinary dermatology, 2015, Volume: 26, Issue:5

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Erythema Multiforme; Isoxazoles; Male; Skin; Zonisamide

2015
Zonisamide: Review of Recent Clinical Evidence for Treatment of Epilepsy.
    CNS neuroscience & therapeutics, 2015, Volume: 21, Issue:9

    Topics: Anticonvulsants; Drug Interactions; Epilepsy; Humans; Isoxazoles; Randomized Controlled Trials as Topic; Zonisamide

2015
Safety and tolerability of an oral zonisamide loading dose.
    Seizure, 2015, Volume: 32

    Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Drug Administration Schedule; Epilepsy; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Middle Aged; Retrospective Studies; Young Adult; Zonisamide

2015
Zonisamide-induced Acute-on-Chronic Liver Failure: First Report.
    Journal of clinical gastroenterology, 2016, Volume: 50, Issue:3

    Topics: Acute-On-Chronic Liver Failure; Adult; Alcoholism; Anticonvulsants; Epilepsy; Female; Humans; Isoxazoles; Zonisamide

2016
Retention, dosing, tolerability and patient reported seizure outcome of Zonisamide as only add-on treatment under real-life conditions in adult patients with partial onset seizures: Results of the observational study ZOOM.
    Seizure, 2016, Volume: 34

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Seizures; Treatment Outcome; Young Adult; Zonisamide

2016
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
    Brain & development, 2016, Volume: 38, Issue:8

    Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide

2016
Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition.
    Epilepsy research, 2008, Volume: 82, Issue:1

    Topics: Animals; Anticonvulsants; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Epilepsy; Hippocampus; Humans; Isoxazoles; Mammals; Protein Isoforms; Structure-Activity Relationship; Substrate Specificity; Zonisamide

2008
The impact of zonisamide on weight. A clinical study in 103 patients with epilepsy.
    Acta neurologica Scandinavica, 2009, Volume: 119, Issue:4

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Body Mass Index; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Middle Aged; Retrospective Studies; Time Factors; Young Adult; Zonisamide

2009
[New antiepileptic drugs].
    La Revue de medecine interne, 2009, Volume: 30, Issue:4

    Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Pregabalin; Triazines; Zonisamide

2009
Reversible erectile dysfunction in a patient with brain tumor-related epilepsy in therapy with zonisamide in add-on.
    The journal of sexual medicine, 2011, Volume: 8, Issue:12

    Topics: Adult; Anticonvulsants; Astrocytoma; Brain Neoplasms; Epilepsy; Erectile Dysfunction; Humans; Isoxazoles; Male; Seizures; Zonisamide

2011
Zonisamide: in Parkinson's disease.
    CNS drugs, 2009, Volume: 23, Issue:8

    Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Epilepsy; Humans; Isoxazoles; Parkinson Disease; Zonisamide

2009
Efficacy and tolerability of zonisamide as add-on in brain tumor-related epilepsy: preliminary report.
    Acta neurologica Scandinavica, 2009, Volume: 120, Issue:3

    Topics: Adult; Anticonvulsants; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Neurologic Examination; Zonisamide

2009
Effectiveness and tolerability of zonisamide in children with epilepsy: a retrospective review.
    Seizure, 2010, Volume: 19, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Evaluation; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Retrospective Studies; Treatment Outcome; Young Adult; Zonisamide

2010
Simultaneous HPLC-UV analysis of rufinamide, zonisamide, lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in deproteinized plasma of patients with epilepsy.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Feb-01, Volume: 878, Issue:3-4

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Felbamate; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Triazines; Triazoles; Ultraviolet Rays; Zonisamide

2010
Zonisamide-related erectile dysfunction.
    The journal of sexual medicine, 2011, Volume: 8, Issue:4

    Topics: Anticonvulsants; Brain Neoplasms; Epilepsy; Humans; Impotence, Vasculogenic; Isoxazoles; Male; Nitric Oxide Synthase; Zonisamide

2011
Acute kidney injury caused by zonisamide-induced hypersensitivity syndrome.
    Internal medicine (Tokyo, Japan), 2010, Volume: 49, Issue:5

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Anticonvulsants; Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Isoxazoles; Male; Patch Tests; Treatment Outcome; Zonisamide

2010
A prospective audit of adjunctive zonisamide in an everyday clinical setting.
    Epilepsy & behavior : E&B, 2010, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Chemotherapy, Adjuvant; Electroencephalography; Epilepsy; Female; Humans; Isoxazoles; Male; Medical Audit; Middle Aged; Prospective Studies; Treatment Outcome; Young Adult; Zonisamide

2010
Urolithiasis on the ketogenic diet with concurrent topiramate or zonisamide therapy.
    Epilepsy research, 2010, Volume: 90, Issue:1-2

    Topics: Anticonvulsants; Child; Child, Preschool; Combined Modality Therapy; Diet, Ketogenic; Epilepsy; Female; Fructose; Humans; Infant; Isoxazoles; Male; Retrospective Studies; Risk Factors; Topiramate; Urolithiasis; Zonisamide

2010
Zonisamide discontinuation due to psychiatric and cognitive adverse events: a case-control study.
    Neurology, 2010, Aug-10, Volume: 75, Issue:6

    Topics: Adult; Anticonvulsants; Case-Control Studies; Cognition Disorders; Epilepsy; Female; Humans; Isoxazoles; Male; Mental Disorders; Middle Aged; Retrospective Studies; Risk Factors; Young Adult; Zonisamide

2010
[Different expression of GluR5 and GluR6 in rat astrocyte induced with coriaria lactone and ATPA].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:4

    Topics: Animals; Animals, Newborn; Astrocytes; Epilepsy; GluK2 Kainate Receptor; Isoxazoles; Lactones; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; RNA, Messenger

2010
The 4-aminopyridine in vitro epilepsy model analyzed with a perforated multi-electrode array.
    Neuropharmacology, 2011, Volume: 60, Issue:7-8

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; CA3 Region, Hippocampal; Disease Models, Animal; Electrodes; Epilepsy; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Mice; Mice, Inbred C57BL; Microarray Analysis; Motion Pictures; Piperazines; Potassium Channel Blockers; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Software; Somatosensory Cortex

2011
Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors.
    Pharmacogenetics and genomics, 2011, Volume: 21, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Adult; Aged; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Epilepsy; Female; Fructose; Genome-Wide Association Study; Humans; Isoxazoles; Male; Middle Aged; Polymorphism, Single Nucleotide; Prevalence; Severity of Illness Index; Topiramate; Young Adult; Zonisamide

2011
The long-term retention of zonisamide in a large cohort of people with epilepsy at a tertiary referral centre.
    Epilepsy research, 2011, Volume: 96, Issue:1-2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Cohort Studies; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Referral and Consultation; Retrospective Studies; Time Factors; Treatment Outcome; Young Adult; Zonisamide

2011
Possible drug-induced hepatopathy in a dog receiving zonisamide monotherapy for treatment of cryptogenic epilepsy.
    The Journal of veterinary medical science, 2011, Volume: 73, Issue:11

    Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Epilepsy; Female; Isoxazoles; Zonisamide

2011
Low serum leptin level is associated with zonisamide-induced weight loss in overweight female epilepsy patients.
    Epilepsy & behavior : E&B, 2012, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Humans; Isoxazoles; Leptin; Linear Models; Middle Aged; Obesity; Prospective Studies; Weight Loss; Young Adult; Zonisamide

2012
[Clinical application of newer anti-epileptic drugs].
    Rinsho shinkeigaku = Clinical neurology, 2012, Volume: 52, Issue:11

    Topics: Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Piracetam; Pregnancy; Pregnancy Complications; Topiramate; Triazines; Zonisamide

2012
[Urolithiasis induced by combined ACTH and zonisamide treatment in a patient with startle induced epilepsy].
    No to hattatsu = Brain and development, 2002, Volume: 34, Issue:5

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Kidney Calculi; Kidney Pelvis; Male; Reflex, Startle; Zonisamide

2002
[Clinical features and treatment of refractory epilepsy in children].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:12

    Topics: Adolescent; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Clobazam; Clonazepam; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Male; Retrospective Studies; Treatment Outcome; Valproic Acid; Zonisamide

2001
Zonisamide-induced restless legs syndrome.
    Neurology, 2003, Jan-14, Volume: 60, Issue:1

    Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Fatigue; Female; Humans; Isoxazoles; Restless Legs Syndrome; Treatment Outcome; Zonisamide

2003
[A five-year-old girl with epilepsy showing forced normalization due to zonisamide].
    No to hattatsu = Brain and development, 2003, Volume: 35, Issue:3

    Topics: Anticonvulsants; Child Behavior Disorders; Child, Preschool; Communication Disorders; Electroencephalography; Epilepsy; Female; Fluvoxamine; Humans; Isoxazoles; Psychoses, Substance-Induced; Zonisamide

2003
Effect of zonisamide on molecular regulation of glutamate and GABA transporter proteins during epileptogenesis in rats with hippocampal seizures.
    Brain research. Molecular brain research, 2003, Aug-19, Volume: 116, Issue:1-2

    Topics: Amino Acid Transport System X-AG; Amygdala; Animals; Anticonvulsants; Blotting, Western; Carrier Proteins; Chlorides; Chronic Disease; Disease Models, Animal; Epilepsy; Ferric Compounds; Frontal Lobe; GABA Plasma Membrane Transport Proteins; Hippocampus; Isoxazoles; Male; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Rats; Rats, Wistar; Zonisamide

2003
Effect of antiepileptic drug monotherapy on crystalluria in children and young adults.
    Journal of neurology, 2003, Volume: 250, Issue:10

    Topics: Adolescent; Anticonvulsants; Child; Epilepsy; Female; Humans; Isoxazoles; Male; Retrospective Studies; Risk Factors; Sex Factors; Thiazines; Urinalysis; Urinary Calculi; Zonisamide

2003
Influence of coadministered antiepileptic drugs on serum zonisamide concentrations in epileptic patients: quantitative analysis based on suitable transforming factor.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Aging; Anticonvulsants; Biological Availability; Body Surface Area; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Male; Patient Selection; Phenytoin; Powders; Regression Analysis; Sex; Tablets; Zonisamide

2003
Anticonvulsant and antiepileptogenic effects of GABAA receptor ligands in pentylenetetrazole-kindled mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:1

    Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Dehydroepiandrosterone Sulfate; Diazepam; Dose-Response Relationship, Drug; Epilepsy; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Isoxazoles; Kindling, Neurologic; Ligands; Mice; Pentylenetetrazole; Pregnanediones; Receptors, GABA-A

2004
Zonisamide-induced depression and mania in patients with epilepsy.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1

    Topics: Adult; Bipolar Disorder; Depression; Epilepsy; Humans; Isoxazoles; Male; Polypharmacy; Treatment Outcome; Zonisamide

2004
Utilization of zonisamide in patients with chronic pain or epilepsy refractory to other treatments: a retrospective, open label, uncontrolled study in a VA hospital.
    Current medical research and opinion, 2004, Volume: 20, Issue:5

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Chronic Disease; Epilepsy; Humans; Isoxazoles; Male; Middle Aged; Pain; Retrospective Studies; Treatment Outcome; Zonisamide

2004
Overview of Japanese experience-controlled and uncontrolled trials.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Adolescent; Age Distribution; Anticonvulsants; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Isoxazoles; Japan; Male; Retrospective Studies; Treatment Outcome; Zonisamide

2004
Safety of zonisamide therapy: prospective follow-up survey.
    Seizure, 2004, Volume: 13 Suppl 1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Incidence; Infant; Isoxazoles; Male; Mental Disorders; Middle Aged; Product Surveillance, Postmarketing; Zonisamide

2004
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Combinations; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid; Zonisamide

2004
Zonisamide monotherapy for epilepsy in children and young adults.
    Pediatric neurology, 2005, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Infant; Isoxazoles; Retrospective Studies; Treatment Outcome; United States; Zonisamide

2005
Clinical experience with zonisamide monotherapy and adjunctive therapy in children with epilepsy at a tertiary care referral center.
    Journal of child neurology, 2005, Volume: 20, Issue:3

    Topics: Adolescent; Anticonvulsants; Chemotherapy, Adjuvant; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electric Stimulation Therapy; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Retrospective Studies; Treatment Outcome; Zonisamide

2005
Lack of pharmacokinetic interactions between steady-state zonisamide and valproic acid in patients with epilepsy.
    Clinical pharmacokinetics, 2005, Volume: 44, Issue:5

    Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Valproic Acid; Zonisamide

2005
[Effective and 15 years experience. New add-on option in epilepsy therapy]].
    MMW Fortschritte der Medizin, 2005, Jun-09, Volume: 147, Issue:23

    Topics: Anticonvulsants; Body Weight; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Approval; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Humans; Isoxazoles; Patient Acceptance of Health Care; Zonisamide

2005
[Control of side effects. Add on therapy demonstrates good tolerance].
    MMW Fortschritte der Medizin, 2005, Jun-09, Volume: 147, Issue:23

    Topics: Anticonvulsants; Body Weight; Controlled Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Patient Acceptance of Health Care; Treatment Outcome; Zonisamide

2005
Long-term efficacy and safety of monotherapy and adjunctive therapy with zonisamide.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Zonisamide

2006
Simultaneous determination of zonisamide, carbamazepine and carbamazepine-10,11-epoxide in infant serum by high-performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2006, Jun-16, Volume: 41, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Infant; Isoxazoles; Zonisamide

2006
Interactions between zonisamide and conventional antiepileptic drugs in the mouse maximal electroshock test model.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:4

    Topics: Animals; Anticonvulsants; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Electroshock; Epilepsy; Fluorescent Antibody Technique; Isoxazoles; Male; Mice; Zonisamide

2007
A long-term follow-up of zonisamide monotherapy.
    Epilepsia, 2006, Volume: 47, Issue:11

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Epilepsy; Female; Follow-Up Studies; Humans; Isoxazoles; Longitudinal Studies; Male; Medical Records; Statistics, Nonparametric; Treatment Outcome; Zonisamide

2006
A case of Moebius syndrome presenting with congenital bilateral vocal cord paralysis.
    European journal of pediatrics, 2007, Volume: 166, Issue:8

    Topics: Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Isoxazoles; Mobius Syndrome; Pregnancy; Pregnancy Complications; Vocal Cord Paralysis; Zonisamide

2007
[Valproate sodium and zonisamide associated interstitial pneumonitis in an infant].
    No to hattatsu = Brain and development, 2007, Volume: 39, Issue:1

    Topics: Anticonvulsants; Epilepsy; Female; Humans; Infant; Isoxazoles; Lung Diseases, Interstitial; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Spasms, Infantile; Valproic Acid; Zonisamide

2007
Erratum to "Safety of zonisamide therapy: prospective follow-up survey.".
    Seizure, 2007, Volume: 16, Issue:1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Incidence; Infant; Isoxazoles; Male; Mental Disorders; Middle Aged; Product Surveillance, Postmarketing; Zonisamide

2007
Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:1

    Topics: Adult; Algorithms; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Monitoring; Epilepsy; Female; Gene Frequency; Genetics, Population; Heterozygote; Homozygote; Humans; Immunoassay; Isoxazoles; Japan; Male; Metabolic Clearance Rate; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Polymorphism, Genetic; Regression Analysis; Valproic Acid; Zonisamide

2007
Psychosis following initiation of zonisamide.
    The American journal of psychiatry, 2007, Volume: 164, Issue:4

    Topics: Anticonvulsants; Epilepsy; Female; Humans; Isoxazoles; Middle Aged; Psychoses, Substance-Induced; Zonisamide

2007
Zonisamide as treatment for seizures.
    The Nurse practitioner, 2007, Volume: 32, Issue:4

    Topics: Adolescent; Anticonvulsants; Child; Epilepsy; Humans; Isoxazoles; Seizures; Zonisamide

2007
Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons.
    Epilepsy research, 2007, Volume: 76, Issue:1

    Topics: Action Potentials; Analysis of Variance; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoxazoles; Neural Inhibition; Neurons; Serotonin; Theophylline; Zonisamide

2007
Neuroleptic malignant syndrome-like state in an epileptic patient with organic brain comorbidity treated with zonisamide and carbamazepine.
    Epilepsia, 2007, Volume: 48, Issue:10

    Topics: Adult; Anticonvulsants; Brain Diseases; Carbamazepine; Comorbidity; Epilepsy; Humans; Isoxazoles; Male; Neuroleptic Malignant Syndrome; Zonisamide

2007
Clinical efficacy of zonisamide in Lennox-Gastaut syndrome: Korean multicentric experience.
    Brain & development, 2008, Volume: 30, Issue:4

    Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Isoxazoles; Korea; Male; Retrospective Studies; Treatment Outcome; Zonisamide

2008
Antiepileptic activity of zonisamide on hippocampal CA3 neurons does not depend on carbonic anhydrase inhibition.
    Epilepsy research, 2008, Volume: 79, Issue:2-3

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Electrophysiology; Epilepsy; Female; Guinea Pigs; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Isoxazoles; Membrane Potentials; Microelectrodes; Neurons; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Theophylline; Zonisamide

2008
Nonlinear pharmacokinetics of CI-912 in adult epileptic patients.
    Therapeutic drug monitoring, 1984, Volume: 6, Issue:3

    Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Isoxazoles; Kinetics; Male; Middle Aged; Oxazoles; Pilot Projects; Zonisamide

1984
Therapeutic concentration of antiepileptic drugs and the severity of epileptogenesis.
    Electroencephalography and clinical neurophysiology. Supplement, 1982, Volume: 36

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Isoxazoles; Phenytoin; Valproic Acid; Zonisamide

1982
3-Sulfamoylmethyl-1,2-benzisoxazole, a new type of anticonvulsant drug. Electroencephalographic profile.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:4

    Topics: Animals; Anticonvulsants; Arousal; Cats; Electroencephalography; Epilepsy; Female; Freezing; Hippocampus; Isoxazoles; Male; Oxazoles; Thalamus; Time Factors; Tungsten; Zonisamide

1980
Population analysis of the dose-dependent pharmacokinetics of zonisamide in epileptic patients.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Cohort Studies; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Humans; Isoxazoles; Male; Software; Zonisamide

1994
Concentrations of zonisamide in serum, free fraction, mixed saliva and cerebrospinal fluid in epileptic children treated with monotherapy.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Protein Binding; Saliva; Zonisamide

1993
Mechanisms of T-type calcium channel blockade by zonisamide.
    Seizure, 1996, Volume: 5, Issue:2

    Topics: Anticonvulsants; Calcium Channel Blockers; Cell Culture Techniques; Epilepsy; Humans; Isoxazoles; Neuroblastoma; Zonisamide

1996
The necessity of adjusting the dosage of zonisamide when coadministered with other anti-epileptic drugs.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Valproic Acid; Zonisamide

1996
Preliminary report on teratogenic effects of zonisamide in the offspring of treated women with epilepsy.
    Epilepsia, 1996, Volume: 37, Issue:12

    Topics: Abnormalities, Drug-Induced; Adult; Anencephaly; Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Isoxazoles; Polypharmacy; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Risk Factors; Zonisamide

1996
Mechanism for reduction of serum folate by antiepileptic drugs during prolonged therapy.
    Journal of the neurological sciences, 1997, Volume: 145, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Demography; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Isoxazoles; Male; Phenobarbital; Time Factors; Valproic Acid; Zonisamide

1997
IgA and IgG2 deficiency associated with zonisamide therapy: a case report.
    Epilepsia, 1997, Volume: 38, Issue:5

    Topics: Anticonvulsants; Epilepsy; Humans; IgA Deficiency; IgG Deficiency; Immunoglobulin A; Immunoglobulin G; Infant; Isoxazoles; Male; Zonisamide

1997
Heat stroke-like episode in a child caused by zonisamide.
    Brain & development, 1997, Volume: 19, Issue:5

    Topics: Anticonvulsants; Biopsy; Child, Preschool; Epilepsy; Fever; Heat Stroke; Humans; Hypohidrosis; Isoxazoles; Male; Skin; Zonisamide

1997
Psychotic episodes during zonisamide treatment.
    Seizure, 2000, Volume: 9, Issue:1

    Topics: Adult; Age Factors; Anticonvulsants; Case-Control Studies; Child; Epilepsy; Female; Humans; Isoxazoles; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychoses, Substance-Induced; Remission Induction; Retrospective Studies; Treatment Outcome; Zonisamide

2000
Two new drugs for epilepsy.
    The Medical letter on drugs and therapeutics, 2000, Apr-17, Volume: 42, Issue:1076

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Drug Interactions; Epilepsy; Humans; Intestinal Absorption; Isoxazoles; Levetiracetam; Nootropic Agents; Oxcarbazepine; Piracetam; Sodium Channel Blockers; Zonisamide

2000
Zonisamide reduces the increase in 8-hydroxy-2'-deoxyguanosine levels formed during iron-induced epileptogenesis in the brains of rats.
    Epilepsia, 2000, Volume: 41, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticonvulsants; Brain Chemistry; Cerebral Cortex; Chlorides; Deoxyguanosine; DNA Damage; Epilepsy; Ferric Compounds; Isoxazoles; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Zonisamide

2000
Zonisamide (Zonegran) for epilepsy.
    The Medical letter on drugs and therapeutics, 2000, Oct-02, Volume: 42, Issue:1089

    Topics: Adult; Anticonvulsants; Ataxia; Biological Availability; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Half-Life; Humans; Isoxazoles; Zonisamide

2000
Effects of combined administration of zonisamide and valproic acid or phenytoin to nitric oxide production, monoamines and zonisamide concentrations in the brain of seizure-susceptible EL mice.
    Brain research bulletin, 2000, Sep-15, Volume: 53, Issue:2

    Topics: Animals; Anticonvulsants; Biogenic Monoamines; Brain; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Isoxazoles; Mice; Mice, Mutant Strains; Nitric Oxide; Phenytoin; Valproic Acid; Zonisamide

2000
Alterations of nitric oxide and monoamines in the brain of the EL mouse treated with phenobarbital and zonisamide.
    Psychiatry and clinical neurosciences, 2001, Volume: 55, Issue:4

    Topics: Animals; Anticonvulsants; Biogenic Monoamines; Brain; Disease Models, Animal; Drug Therapy, Combination; Epilepsy; Isoxazoles; Mice; Mice, Neurologic Mutants; Nitric Oxide; Phenobarbital; Receptors, N-Methyl-D-Aspartate; Zonisamide

2001
Influences of caffeine to nitric oxide production and zonisamide concentration in the brain of seizure-susceptible EL mice.
    Psychiatry and clinical neurosciences, 2001, Volume: 55, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Caffeine; Central Nervous System Stimulants; Drug Interactions; Epilepsy; Isoxazoles; Mice; Mice, Neurologic Mutants; Nitric Oxide; Zonisamide

2001
[A case of epilepsy after therapy with interferon-alpha-treated chronic hepatitis C].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2002, Volume: 99, Issue:2

    Topics: Anticonvulsants; Electroencephalography; Epilepsy; Hepatitis C, Chronic; Humans; Interferon-alpha; Isoxazoles; Male; Middle Aged; Zonisamide

2002
Pharmacokinetics of zonisamide in perinatal period.
    Brain & development, 2002, Volume: 24, Issue:2

    Topics: Adult; Anticonvulsants; Chromatography, High Pressure Liquid; Epilepsy; Female; Fetal Blood; Humans; Infant, Newborn; Isoxazoles; Milk, Human; Pregnancy; Pregnancy Complications; Zonisamide

2002
Clobazam shows a different antiepileptic action profile from clonazepam and zonisamide in Ihara epileptic rats.
    Epilepsy research, 2002, Volume: 49, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Circadian Rhythm; Clobazam; Clonazepam; Epilepsy; Epilepsy, Tonic-Clonic; Isoxazoles; Male; Rats; Rats, Mutant Strains; Zonisamide

2002
Methodological requirements for clinical trials in refractory epilepsies--our experience with zonisamide.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clinical Trials as Topic; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Humans; Infant; Isoxazoles; Research Design; Zonisamide

1992
Factors influencing serum concentration of zonisamide in epileptic patients.
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Zonisamide

1992
Monotherapy for childhood epilepsies with zonisamide.
    The Japanese journal of psychiatry and neurology, 1991, Volume: 45, Issue:2

    Topics: Administration, Oral; Adolescent; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Neurologic Examination; Zonisamide

1991
Effect of zonisamide on serum immunoglobulins.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Isoxazoles; Male; Middle Aged; Zonisamide

1990
Effect of a novel anticonvulsant, zonisamide (AD-810, CI-912), in an experimental model of photosensitive epilepsy.
    Epilepsy research, 1990, Volume: 7, Issue:2

    Topics: Animals; Anticonvulsants; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Epilepsy; Female; Isoxazoles; Male; Photic Stimulation; Zonisamide

1990
Anticonvulsant effects of zonisamide and phenytoin on seizure activity of the feline visual cortex.
    Brain & development, 1990, Volume: 12, Issue:2

    Topics: Animals; Anticonvulsants; Cats; Dose-Response Relationship, Drug; Epilepsy; Female; Isoxazoles; Kindling, Neurologic; Male; Oxazoles; Phenytoin; Visual Cortex; Zonisamide

1990
Suppressive effects of intranigral injection of muscimol in three models of generalized non-convulsive epilepsy induced by chemical agents.
    Brain research, 1989, Sep-25, Volume: 498, Issue:1

    Topics: 4-Butyrolactone; Animals; Convulsants; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra

1989
Development of tolerance to the anticonvulsant effect of GABAmimetic drugs in genetically epilepsy-prone gerbils.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4

    Topics: Acetates; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Diazepam; Drug Tolerance; Epilepsy; Female; gamma-Aminobutyric Acid; Gerbillinae; Isoxazoles; Male; Oxazoles; Valproic Acid

1986
The antiepileptic effect of zonisamide on patients with refractory seizures and its side effect.
    The Japanese journal of psychiatry and neurology, 1988, Volume: 42, Issue:3

    Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Evoked Potentials; Female; Humans; Isoxazoles; Male; Oxazoles; Zonisamide

1988
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Carbamazepine; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Humans; Isoxazoles; Kinetics; Male; Oxazoles; Phenytoin; Zonisamide

1986