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deferoxamine and Epilepsy

deferoxamine has been researched along with Epilepsy in 5 studies

Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
" This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model."7.85Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats. ( Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X, 2017)
" This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model."3.85Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats. ( Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Lorenzo, F1
Di Lorenzo, B1
Zou, X1
Jiang, S1
Wu, Z1
Shi, Y1
Cai, S1
Zhu, R1
Chen, L1
Suzer, T1
Coskun, E1
Demir, S1
Tahta, K1
Laur, OIu1
Gusakov, IV1
Ivanenko, AI1
Andreoli, SP1
Chesney, RW1
Salusky, IB1
Sedman, AB1

Other Studies

5 other studies available for deferoxamine and Epilepsy

ArticleYear
Iron and aluminum in Alzheimer's disease.
    Neuro endocrinology letters, 2013, Volume: 34, Issue:6

    Topics: Aged; Aluminum; Alzheimer Disease; Antioxidants; Ascorbic Acid; Chelation Therapy; Deferoxamine; Epi

2013
Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats.
    Brain research, 2017, 03-01, Volume: 1658

    Topics: Animals; Anticonvulsants; Blotting, Western; Brain; Chlorides; Deferoxamine; Disease Models, Animal;

2017
Lipid peroxidation and glutathione levels after cortical injection of ferric chloride in rats: effect of trimetazidine and deferoxamine.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 2000, Volume: 199, Issue:4

    Topics: Analysis of Variance; Animals; Brain; Chelating Agents; Deferoxamine; Epilepsy; Ferrous Compounds; G

2000
[Effects of desferrioxamine (desferal) on the formation of epileptic focus in rats after subdural injection of blood].
    Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 113, Issue:4

    Topics: Animals; Blood; Deferoxamine; Dura Mater; Electroencephalography; Epilepsy; Hematoma, Subdural; Inje

1992
What treatment would you advise for a 1-year-old child with chronic renal failure who has been on aluminum hydroxide as a phosphate binder for 6 months and then develops epilepsy and is found to have a grossly raised plasma aluminum concentration?
    Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:4

    Topics: Aluminum; Aluminum Hydroxide; Deferoxamine; Epilepsy; Humans; Infant; Kidney Failure, Chronic

1990