deferoxamine has been researched along with Epilepsy in 5 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Excerpt | Relevance | Reference |
---|---|---|
" This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model." | 7.85 | Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats. ( Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X, 2017) |
" This study is to examine the potential epilepsy control effect of deferoxamine (DFO), an iron chelator, on a ferric chloride-induced epilepsy rat model." | 3.85 | Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats. ( Cai, S; Chen, L; Jiang, S; Shi, Y; Wu, Z; Zhu, R; Zou, X, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Di Lorenzo, F | 1 |
Di Lorenzo, B | 1 |
Zou, X | 1 |
Jiang, S | 1 |
Wu, Z | 1 |
Shi, Y | 1 |
Cai, S | 1 |
Zhu, R | 1 |
Chen, L | 1 |
Suzer, T | 1 |
Coskun, E | 1 |
Demir, S | 1 |
Tahta, K | 1 |
Laur, OIu | 1 |
Gusakov, IV | 1 |
Ivanenko, AI | 1 |
Andreoli, SP | 1 |
Chesney, RW | 1 |
Salusky, IB | 1 |
Sedman, AB | 1 |
5 other studies available for deferoxamine and Epilepsy
Article | Year |
---|---|
Iron and aluminum in Alzheimer's disease.
Topics: Aged; Aluminum; Alzheimer Disease; Antioxidants; Ascorbic Acid; Chelation Therapy; Deferoxamine; Epi | 2013 |
Effectiveness of deferoxamine on ferric chloride-induced epilepsy in rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Brain; Chlorides; Deferoxamine; Disease Models, Animal; | 2017 |
Lipid peroxidation and glutathione levels after cortical injection of ferric chloride in rats: effect of trimetazidine and deferoxamine.
Topics: Analysis of Variance; Animals; Brain; Chelating Agents; Deferoxamine; Epilepsy; Ferrous Compounds; G | 2000 |
[Effects of desferrioxamine (desferal) on the formation of epileptic focus in rats after subdural injection of blood].
Topics: Animals; Blood; Deferoxamine; Dura Mater; Electroencephalography; Epilepsy; Hematoma, Subdural; Inje | 1992 |
What treatment would you advise for a 1-year-old child with chronic renal failure who has been on aluminum hydroxide as a phosphate binder for 6 months and then develops epilepsy and is found to have a grossly raised plasma aluminum concentration?
Topics: Aluminum; Aluminum Hydroxide; Deferoxamine; Epilepsy; Humans; Infant; Kidney Failure, Chronic | 1990 |