sumatriptan has been researched along with Epilepsy in 7 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serotonin and fluoxetine, but not sumatriptan, alleviated PTZ-induced seizures by prolonging onset times of myoclonic-jerk and generalized tonic-clonic seizures." | 8.12 | Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats. ( Kilinc, E; Kılınc, YB; Torun, IE, 2022) |
| "Topiramate is a new antiepileptic drug (AED) that has been approved worldwide (in more than 80 countries) for the treatment of various kinds of epilepsy." | 4.82 | Pharmacokinetic interactions of topiramate. ( Bialer, M; Curtin, C; Doose, DR; Murthy, B; Schwabe, S; Twyman, RE; Wang, SS, 2004) |
| "Serotonin and fluoxetine, but not sumatriptan, alleviated PTZ-induced seizures by prolonging onset times of myoclonic-jerk and generalized tonic-clonic seizures." | 4.12 | Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats. ( Kilinc, E; Kılınc, YB; Torun, IE, 2022) |
| " The proportions of outcomes with birth defects are as follows: in the Acyclovir (antiviral medication) Pregnancy Registry (1984-1998) (19/581), 3." | 3.70 | Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment. ( Andrews, EB; Ephross, SA; Heffner, CR; Reiff-Eldridge, R; Tennis, PS; White, AD, 2000) |
| "Headache is one of the most common symptoms of COVID." | 2.82 | Post-COVID Headache: A Literature Review. ( Chhabra, N; Grill, MF; Singh, RBH, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Torun, IE | 1 |
| Kılınc, YB | 1 |
| Kilinc, E | 1 |
| Chhabra, N | 1 |
| Grill, MF | 1 |
| Singh, RBH | 1 |
| Bialer, M | 1 |
| Doose, DR | 1 |
| Murthy, B | 1 |
| Curtin, C | 1 |
| Wang, SS | 1 |
| Twyman, RE | 1 |
| Schwabe, S | 1 |
| Jacob, J | 1 |
| Goadsby, PJ | 1 |
| Duncan, JS | 1 |
| Ogunyemi, A | 1 |
| Adams, D | 1 |
| Putnam, GP | 1 |
| O'Quinn, S | 1 |
| Bolden-Watson, CP | 1 |
| Davis, RL | 1 |
| Gutterman, DL | 1 |
| Fox, AW | 1 |
| Reiff-Eldridge, R | 1 |
| Heffner, CR | 1 |
| Ephross, SA | 1 |
| Tennis, PS | 1 |
| White, AD | 1 |
| Andrews, EB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Sumatriptan and Naratriptan Pregnancy Registry[NCT01059604] | 868 participants (Actual) | Observational [Patient Registry] | 2001-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for sumatriptan and Epilepsy
| Article | Year |
|---|---|
Post-COVID Headache: A Literature Review.
Topics: COVID-19; Epilepsy; Female; Headache; Humans; Migraine Disorders; Sumatriptan | 2022 |
Pharmacokinetic interactions of topiramate.
Topics: Anticonvulsants; Area Under Curve; Contraceptives, Oral; Drug Interactions; Epilepsy; Fructose; Half | 2004 |
5 other studies available for sumatriptan and Epilepsy
| Article | Year |
|---|---|
Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats.
Topics: Animals; Anticonvulsants; Epilepsy; Fluoxetine; Humans; Interleukin-6; Male; Neuroinflammatory Disea | 2022 |
Use of sumatriptan in post-ictal migraine headache.
Topics: Adult; Epilepsy; Female; Humans; Male; Middle Aged; Migraine Disorders; Sumatriptan | 1996 |
Migraine-like symptoms triggered by occipital lobe seizures: response to sumatriptan.
Topics: Adult; Electroencephalography; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Male; Migraine | 1998 |
Migraine polypharmacy and the tolerability of sumatriptan: a large-scale, prospective study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-As | 1999 |
Monitoring pregnancy outcomes after prenatal drug exposure through prospective pregnancy registries: a pharmaceutical company commitment.
Topics: Abnormalities, Drug-Induced; Acyclovir; Anticonvulsants; Antiviral Agents; Drug Industry; Epilepsy; | 2000 |