sotalol has been researched along with Epilepsy in 3 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Excerpt | Relevance | Reference |
---|---|---|
"Sotalol as a drug blocking β-receptors and potassium KCNH2 channels may interact with different substances that affect seizures." | 3.85 | Sotalol enhances the anticonvulsant action of valproate and diphenylhydantoin in the mouse maximal electroshock model. ( Banach, M; Borowicz-Reutt, KK; Popławska, M, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (66.67) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Banach, M | 1 |
Popławska, M | 1 |
Borowicz-Reutt, KK | 1 |
Sieber, C | 1 |
Weiss, P | 1 |
Follath, F | 1 |
Brown, DC | 1 |
Godman, MJ | 1 |
3 other studies available for sotalol and Epilepsy
Article | Year |
---|---|
Sotalol enhances the anticonvulsant action of valproate and diphenylhydantoin in the mouse maximal electroshock model.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Avoidance Learning; Brain; Disease Models, Animal; | 2017 |
[Hemiparesis and torsade de pointes under low-dose sotalol therapy].
Topics: Aged; Aged, 80 and over; Cardiac Complexes, Premature; Electrocardiography; Epilepsy; Female; Hemipl | 1990 |
Life threatening 'epilepsy'.
Topics: Child, Preschool; Diagnosis, Differential; Epilepsy; Female; Humans; Sotalol; Tachycardia; Unconscio | 1991 |