Page last updated: 2024-11-01

ondansetron and Epilepsy

ondansetron has been researched along with Epilepsy in 2 studies

Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"A generalized tonic-clonic seizure occurred in each patient--12, 15, and 22 min after injection."5.35Ondansetron and seizures. ( Acharya, JN; Rai, A; Selhorst, JB; Singh, NN, 2009)
"A generalized tonic-clonic seizure occurred in each patient--12, 15, and 22 min after injection."1.35Ondansetron and seizures. ( Acharya, JN; Rai, A; Selhorst, JB; Singh, NN, 2009)
"The effects of seizures were observed to a much larger extent in malformed than in normal brain tissue."1.33Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development. ( Bassanini, S; Battaglia, G; Caccia, S; Chimenti, S; Gagliardi, B; Guiso, G; Marchi, N; Noé, F; Ravizza, T; Rizzi, M; Vezzani, A, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Singh, NN1
Rai, A1
Selhorst, JB1
Acharya, JN1
Marchi, N1
Guiso, G1
Caccia, S1
Rizzi, M1
Gagliardi, B1
Noé, F1
Ravizza, T1
Bassanini, S1
Chimenti, S1
Battaglia, G1
Vezzani, A1

Other Studies

2 other studies available for ondansetron and Epilepsy

ArticleYear
Ondansetron and seizures.
    Epilepsia, 2009, Volume: 50, Issue:12

    Topics: Adult; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans;

2009
Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development.
    Neurobiology of disease, 2006, Volume: 24, Issue:3

    Topics: Animals; Anticonvulsants; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood

2006