sulforaphane has been researched along with Epilepsy in 5 studies
sulforaphane: from Cardaria draba L.
sulforaphane : An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulforaphane (SFN) is a thiol compound found in wide abundance in cruciferous plants that has numerous reported therapeutic efficacies." | 1.46 | Sulforaphane protects against sodium valproate-induced acute liver injury. ( Atef, H; El-Khouly, OA; Nazmy, EA; Said, E, 2017) |
| "Sulforaphane was anticonvulsant in two acute mouse models of epilepsy and protected mice against pilocarpine-induced status epilepticus (SE)." | 1.42 | Sulforaphane is anticonvulsant and improves mitochondrial function. ( Borges, K; Carrasco-Pozo, C; Tan, KN, 2015) |
| "Sulforaphane (SF) was used to activate Nrf2-ARE signal pathway." | 1.40 | Activation of Nrf2-ARE signal pathway protects the brain from damage induced by epileptic seizure. ( Fang, H; Wang, H; Wang, W; Wu, Y; Xie, T; Zang, H; Zhang, G, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pauletti, A | 2 |
| Terrone, G | 2 |
| Shekh-Ahmad, T | 2 |
| Salamone, A | 2 |
| Ravizza, T | 2 |
| Rizzi, M | 2 |
| Pastore, A | 2 |
| Pascente, R | 2 |
| Liang, LP | 2 |
| Villa, BR | 2 |
| Balosso, S | 2 |
| Abramov, AY | 2 |
| van Vliet, EA | 2 |
| Del Giudice, E | 2 |
| Aronica, E | 2 |
| Antoine, DJ | 1 |
| Patel, M | 2 |
| Walker, MC | 2 |
| Vezzani, A | 2 |
| Wang, W | 2 |
| Wu, Y | 1 |
| Zhang, G | 1 |
| Fang, H | 1 |
| Wang, H | 1 |
| Zang, H | 1 |
| Xie, T | 1 |
| Carrasco-Pozo, C | 1 |
| Tan, KN | 1 |
| Borges, K | 1 |
| Nazmy, EA | 1 |
| El-Khouly, OA | 1 |
| Atef, H | 1 |
| Said, E | 1 |
5 other studies available for sulforaphane and Epilepsy
| Article | Year |
|---|---|
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Disease Models, Animal; Drug | 2017 |
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Case-Control Studies; Cell Count; Cognitive Dysfunc | 2019 |
Activation of Nrf2-ARE signal pathway protects the brain from damage induced by epileptic seizure.
Topics: Amygdala; Animals; Antioxidant Response Elements; Electric Stimulation; Epilepsy; Hippocampus; Isoth | 2014 |
Sulforaphane is anticonvulsant and improves mitochondrial function.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electron Transport Complex I; Electro | 2015 |
Sulforaphane protects against sodium valproate-induced acute liver injury.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Anticonvulsants; A | 2017 |