tannins and Epilepsy

tannins has been researched along with Epilepsy* in 2 studies

Other Studies

2 other study(ies) available for tannins and Epilepsy

Article	Year
Ethnopharmacology of Q'eqchi' Maya antiepileptic and anxiolytic plants: effects on the GABAergic system. Journal of ethnopharmacology, 2009, Sep-07, Volume: 125, Issue:2 The Q'eqchi' Maya possess a large selection of plants to treat neurological disorders, including epilepsy and susto (fright), a culture-bound illness related to anxiety disorders.. To investigate the activity of antiepileptic and anxiolytic plants in the GABAergic system, and determine if there is a pharmacological basis for plant selection.. Ethanol extracts of 34 plants were tested in vitro for their ability to inhibit GABA-transaminase (GABA-T) or bind to the GABA(A)-benzodiazepine (BZD) receptor, two principal drug targets in epilepsy and anxiety. Pharmacological activity was correlated with relative frequency of use, based on informant consensus.. Ten plants showed greater than 50% GABA-T inhibition at 1mg/ml, while 23 showed greater than 50% binding to the GABA(A)-BZD receptor at 250 microg/ml. Piperaceae, Adiantaceae and Acanthaceae families were highly represented and active in both assays. There was a significant positive correlation between GABA-T inhibition and relative frequency of use for epilepsy, and an even stronger correlation between GABA(A) binding and relative frequency of use for susto (fright).. Clearly, Q'eqchi' traditional knowledge of antiepileptic and anxiolytic plants is associated with the use of pharmacologically active plants. Based on the evidence, it is suggested that the mechanism of action for some traditionally used plants may be mediated through the GABAergic system. Topics: 4-Aminobutyrate Transaminase; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Belize; Epilepsy; Ethnopharmacology; Humans; Indians, Central American; Magnoliopsida; Medicine, Traditional; Phytotherapy; Plant Extracts; Plants, Medicinal; Receptors, GABA-A; Tannins	2009
[Detection of serum anti-milk antibody by radioimmunoelectrophoresis and radioimmunodiffusion]. Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1969, Jul-01, Volume: 73, Issue:7 Topics: Adolescent; Age Factors; Agglutination Tests; Animals; Antibodies; Child; Child, Preschool; Epilepsy; Female; gamma-Globulins; Gastrointestinal Diseases; Humans; Immunodiffusion; Immunoelectrophoresis; Infant; Infant, Newborn; Iodine Isotopes; Male; Milk; Respiratory Tract Diseases; Serum Albumin, Bovine; Skin Diseases; Tannins	1969

Article

Year

Ethnopharmacology of Q'eqchi' Maya antiepileptic and anxiolytic plants: effects on the GABAergic system.

Journal of ethnopharmacology, 2009, Sep-07, Volume: 125, Issue:2

The Q'eqchi' Maya possess a large selection of plants to treat neurological disorders, including epilepsy and susto (fright), a culture-bound illness related to anxiety disorders.. To investigate the activity of antiepileptic and anxiolytic plants in the GABAergic system, and determine if there is a pharmacological basis for plant selection.. Ethanol extracts of 34 plants were tested in vitro for their ability to inhibit GABA-transaminase (GABA-T) or bind to the GABA(A)-benzodiazepine (BZD) receptor, two principal drug targets in epilepsy and anxiety. Pharmacological activity was correlated with relative frequency of use, based on informant consensus.. Ten plants showed greater than 50% GABA-T inhibition at 1mg/ml, while 23 showed greater than 50% binding to the GABA(A)-BZD receptor at 250 microg/ml. Piperaceae, Adiantaceae and Acanthaceae families were highly represented and active in both assays. There was a significant positive correlation between GABA-T inhibition and relative frequency of use for epilepsy, and an even stronger correlation between GABA(A) binding and relative frequency of use for susto (fright).. Clearly, Q'eqchi' traditional knowledge of antiepileptic and anxiolytic plants is associated with the use of pharmacologically active plants. Based on the evidence, it is suggested that the mechanism of action for some traditionally used plants may be mediated through the GABAergic system.

Topics: 4-Aminobutyrate Transaminase; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Belize; Epilepsy; Ethnopharmacology; Humans; Indians, Central American; Magnoliopsida; Medicine, Traditional; Phytotherapy; Plant Extracts; Plants, Medicinal; Receptors, GABA-A; Tannins

2009

[Detection of serum anti-milk antibody by radioimmunoelectrophoresis and radioimmunodiffusion].

Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1969, Jul-01, Volume: 73, Issue:7

Topics: Adolescent; Age Factors; Agglutination Tests; Animals; Antibodies; Child; Child, Preschool; Epilepsy; Female; gamma-Globulins; Gastrointestinal Diseases; Humans; Immunodiffusion; Immunoelectrophoresis; Infant; Infant, Newborn; Iodine Isotopes; Male; Milk; Respiratory Tract Diseases; Serum Albumin, Bovine; Skin Diseases; Tannins

1969