Page last updated: 2024-10-31

neostigmine and Epilepsy

neostigmine has been researched along with Epilepsy in 6 studies

Neostigmine: A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike PHYSOSTIGMINE, does not cross the blood-brain barrier.
neostigmine : A quaternary ammonium ion comprising an anilinium ion core having three methyl substituents on the aniline nitrogen, and a 3-[(dimethylcarbamoyl)oxy] substituent at position 3. It is a parasympathomimetic which acts as a reversible acetylcholinesterase inhibitor.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"Neostigmine effects were blocked by atropine (1 microM), confirming their muscarinic nature."1.36Anticholinesterase-induced epileptiform activity in immature rat piriform cortex slices, in vitro. ( Aitchison, E; Constanti, A; Weston, SE; Whalley, BJ, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aitchison, E1
Weston, SE1
Constanti, A1
Whalley, BJ1
HOFFER, A1
NOBILE, M2
PELLEGRINO, G2
Riehl, JL1
Lee, DK1
Andrews, JM1
Brown, WJ1
Norman, J1
Mazars, Y1
Mazars, G1
Piot, C1

Other Studies

6 other studies available for neostigmine and Epilepsy

ArticleYear
Anticholinesterase-induced epileptiform activity in immature rat piriform cortex slices, in vitro.
    Neuroscience letters, 2010, Apr-12, Volume: 473, Issue:3

    Topics: Acetylcholine; Acetylcholinesterase; Action Potentials; Animals; Cholinesterase Inhibitors; Epilepsy

2010
Induction of sleep by autonomic drugs.
    The Journal of nervous and mental disease, 1954, Volume: 119, Issue:5

    Topics: Acetylcholine; Atropine; Autonomic Agents; Epilepsy; Humans; Neostigmine; Schizophrenia; Schizophren

1954
[Effects of prostigmine on disposition toward Brown-Sequard epilepsy].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:6

    Topics: Epilepsy; Humans; Neostigmine

1956
[Effects of prostigmine on disposition toward Brown-Sequard epilepsy].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:6

    Topics: Epilepsy; Humans; Neostigmine

1956
[Effects of prostigmine on disposition toward Brown-Sequard epilepsy].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:6

    Topics: Epilepsy; Humans; Neostigmine

1956
[Effects of prostigmine on disposition toward Brown-Sequard epilepsy].
    Bollettino della Societa italiana di biologia sperimentale, 1956, Volume: 32, Issue:6

    Topics: Epilepsy; Humans; Neostigmine

1956
Electrophysiological and neuropharmacological studies in a patient with Unverricht-Lafora's disease.
    Neurology, 1967, Volume: 17, Issue:5

    Topics: Amphetamine; Atropine; Child; Chlordiazepoxide; Cytoplasmic Granules; Diphenhydramine; Electroenceph

1967
Resistance to vecuronium.
    Anaesthesia, 1993, Volume: 48, Issue:12

    Topics: Adult; Carbamazepine; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Neostigmine

1993
[Favorable action of prostigmine in certain cases of centrencephalic epilepsy].
    Revue neurologique, 1966, Volume: 114, Issue:3

    Topics: Adolescent; Child; Epilepsy; Female; Humans; Neostigmine

1966