Page last updated: 2024-08-24

adenosine and Epilepsy

adenosine has been researched along with Epilepsy in 115 studies

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	12 (10.43)	18.7374
1990's	24 (20.87)	18.2507
2000's	33 (28.70)	29.6817
2010's	30 (26.09)	24.3611
2020's	16 (13.91)	2.80

Authors

Authors	Studies
Guo, M; Li, T	1
Chen, L; Chen, Y; Jiao, K; Law, WJ; McMahon, L; Pati, S; Pizarro, D; Saggu, S; Wang, Q	1
Faingold, CL; Feng, HJ	1
Bertoncello, KT; Bonan, CD	1
Alves, M; Boison, D; Purnell, BS	1
Cui, Y; Li, X; Lin, Y; Ma, W; Qiu, W; Wang, Q; Wang, Y; Wei, F; Xiong, H; Xu, R; Zhu, J	1
Boison, D; Daniels, SD	1
Boison, D; Rho, JM	1
Li, T; Wang, X	1
Chen, F; Liu, H; Luo, L; Ma, H; Qu, X; Xu, H; Yang, L; Zhang, R; Zhu, H	1
Costa Cruz, PH; Kawahara, Y	1
Becker, PH; Benoist, JF; Davit-Spraul, A; Demir, Z; Gaignard, P; Gonzales, E; Habes, D; Imbard, A; Jacquemin, E; Mozer Glassberg, Y; Mussini, C; Rozenfeld Bar Lev, M; Sevin, C; Slama, A; Thérond, P	1
Okada, S; Sakurai, M; Yang, Y	1
Alves, M; Beamer, E; Conte, G; Dale, N; de Diego-Garcia, L; Delanty, N; El-Naggar, H; Engel, T; Henshall, DC; Khalil, M; Lacey, A; Rosenow, F; Tian, F	1
Binder, DK; Steinhäuser, C	1
Beamer, E; Boison, D; Engel, T; Kuchukulla, M	1
Gou, Y; Luo, L; Shan, P; Zhang, J; Zhu, S	1
Huang, H; Li, D; Luo, Z; Peng, Y; Qiu, X; Wang, J; Xu, P; Xu, Z; Zhang, J	1
da Silva, RS; Machado Torresini, F; Menezes, FP; Nery, LR	1
Adamec, J; Grove, R; Madhavan, D; Roundtree, HM; Samson, KK; Simeone, KA; Simeone, TA; Smith, DD; Warren, TJ	1
Frenguelli, BG; Hall, J	1
Boison, D; Reemmer, J; Weltha, L	1
Hendricks, WD; Schnell, E; Westbrook, GL	1
Kowalski, A; Kuśmirowska, K; Rebas, E	1
Boison, D; Farrell, JM; Kaplan, DL; Lusardi, TA; Lytle, NK; Pritchard, EM; Sandau, US; Williams-Karnesky, RL	1
Bae, N; Booher, ME; Cox, T; Gabriel, GJ; He, C; Iacoban, P; Olsen, MJ; Rowles, J; Tribbey, L; Wang, GZ; Zheng, G; Zhou, L	1
Kotowski, J; Świąder, MJ; Łuszczki, JJ	1
Boison, D	10
Faingold, CL; Kommajosyula, SP; Randall, ME	1
Boison, D; Faingold, CL; Richerson, GB; Ryvlin, P	1
Abunassar, J; Chong, AY; Hibbert, B; Le May, MR; Malhotra, N; Pourdjabbar, A; So, DY; Whitten, TA	1
Cieślak, M; Komoszyński, M; Wojtczak, A	1
Boison, D; Kaplan, DL; Lan, JQ; Li, T; Pritchard, EM; Wilz, A	1
Matar, KM	1
Bonan, CD; Morsch, VM; Schetinger, MR; Wyse, AT	1
Arcella, A; Cantore, G; Di Gennaro, G; Esposito, V; Eusebi, F; Fredholm, BB; Fucile, S; Limatola, C; Manfredi, M; Martinello, K; Mascia, A; Miledi, R; Piccari, V; Quarato, PP; Roseti, C; Simonato, M	1
Alptekin, M; Erkutlu, I; Kurtul, N; Pençe, S; Tan, U	1
Boison, D; Kaplan, DL; Li, T; Lusardi, TA; Pritchard, EM; Szybala, C; Wilz, A	1
Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM	1
Boison, D; Li, T; Shen, HY	1
Boison, D; Stewart, KA	1
McCown, TJ	1
Fathollahi, Y; Mirnajafizadeh, J; Salmani, ME; Semnanian, S	1
Boison, D; Boon, P; Raedt, R; Theofilas, P; Van Dycke, A; Verstraete, A; Vonck, K; Wadman, W	1
Burnstock, G; Fredholm, BB; Verkhratsky, A	1
Boon, P; Raedt, R; Van Dycke, A; Vonck, K	1
Ankarali, S; Ayyildiz, M; Marangoz, AH; Marangoz, C; Yildirim, M	1
Kostopoulos, G; Moschovos, C; Papatheodoropoulos, C	1
Olsen, M; Powers, R; Rowles, J; Wong, M	1
Li, TF; Luan, GM	1
Binder, DK; Fiacco, TA; Hsu, MS; Hubbard, JA	1
Aebischer, P; Boison, D; Déglon, N; Huber, A; Möhler, H; Padrun, V	1
Almasi, M; Fathollahi, Y; Firoozabadi, P; Mohammad, S; Omrani, A; Semnanian, S	1
Amaral, O; Battastini, AM; Bonan, CD; Bruno, AN; Coitinho, A; Oses, JP; Sarkis, JJ	1
Bernays, R; Blau, N; Boison, D; Imhof, HG; Rudolph, U; Wieser, HG; Yonekawa, Y	1
Namiki, A; Ohmori, H; Sato, Y	1
Dobelis, P; Dulla, CG; Frenguelli, BG; Masino, SA; Pearson, T; Staley, KJ	1
Boison, D; Fedele, DE; Kaplan, DL; Meinel, L; Merkle, HP; Schumacher, C; Uebersax, L	1
Asimakopoulos, B; Efthimiadou, A; Nikolettos, NK; Pagonopoulou, O	1
Marangoz, C; Yildirim, M	1
Ahmadi, B; Akhondzadeh, S; Motamedi, M; Razeghi, S; Togha, M	1
Boison, D; Brüstle, O; Koch, P; Lan, JQ; Li, T; Lusardi, T; Segschneider, M; Simon, RP; Steinbeck, JA; Wilz, A	1
Lewin, E	1
Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE	1
Foster, AC; Miller, LP; Wiesner, JB	1
Beani, L; Bianchi, C; Borea, PA; Muzzolini, A; Simonato, M; Varani, K	1
Bingmann, D; Moraidis, I	1
Hosseinzadeh, H; Stone, TW	1
Hattori, Y; Hayashi, Y; Hori, Y; Islam, N; Moriwaki, A	1
Hattori, Y; Hayashi, Y; Hori, Y; Moriwaki, A	1
Berman, RF; Janusz, CA	1
Fochtmann, L; Francis, A	1
Brodie, MJ; Ross, FM; Stone, TW	1
Brown, JK; O'Regan, ME	1
Bosschaart, AN; Duran, M; Hageman, G; Tien Poll-The, B; van den Bergh, FA	1
Chesi, AJ; Stone, TW	1
Dale, TJ; Dupere, JR; Starkey, SJ; Xie, X	1
Giraldez, L; Girardi, E	1
Borowicz, KK; Czuczwar, SJ; Kleinrok, Z	1
Stringer, JL; Xiong, ZQ	1
Blondeau, N; Heurteaux, C; Lazdunski, M; Plamondon, H; Richelme, C	1
Haas, HL; Selbach, O	1
Ates, N; Ilbay, G; Karson, A; Sahin, D	1
Georgiev, V; Kambourova, T; Tchekalarova, J	1
He, RR; Wang, H; Wang, ZA	1
Hattori, Y; Hayashi, Y; Hori, Y; Lu, YF; Moriwaki, A	1
Birnstiel, S; Gerber, U; Greene, RW	1
Schubert, P	1
Gale, K; Miller, LP; Murray, TF; Zhong, P	1
During, MJ; Spencer, DD	1
Greene, RW; Haas, HL	1
Dragunow, M	2
Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B	1
Angelatou, F; Kostopoulos, G; Pagonopoulou, O	1
Bartrup, JT; Connick, JH; Stone, TW	1
Hattori, Y	1
Avoli, M; Drapeau, C; Kostopoulos, G; Olivier, A; Villemeure, JG	1
Chin, JH	1
Ault, B; Wang, CM	1
Caporali, MG; Niglio, T; Popoli, P; Scotti de Carolis, A	1
O'Brien, DR	1
Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A	1
Dóra, E; Kovách, AG	1
Chesielski, L; Kempf, E; Lehmann, A; Maitre, M; Mandel, P	1
Hankiewicz, J; Lesniak, M	1

Reviews

38 review(s) available for adenosine and Epilepsy

Article	Year
Adenosine Dysfunction in Epilepsy and Associated Comorbidities. Current drug targets, 2022, Volume: 23, Issue:4 Topics: Adenosine; Adenosine Kinase; Anticonvulsants; Epilepsy; Humans; Seizures	2022
A unified hypothesis of SUDEP: Seizure-induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the periaqu Epilepsia, 2023, Volume: 64, Issue:4 Topics: Adenosine; Animals; Death, Sudden; Epilepsy; Humans; Periaqueductal Gray; Respiratory Insufficiency; Return of Spontaneous Circulation; Seizures; Serotonin; Sudden Unexpected Death in Epilepsy	2023
Astrocyte-neuron circuits in epilepsy. Neurobiology of disease, 2023, Volume: 179 Topics: Adenosine; Astrocytes; Epilepsy; Glutamic Acid; Humans; Neurons	2023
Bipolar mania and epilepsy pathophysiology and treatment may converge in purine metabolism: A new perspective on available evidence. Neuropharmacology, 2023, Dec-15, Volume: 241 Topics: Adenosine; Adenosine Triphosphate; Antimanic Agents; Bipolar Disorder; Epilepsy; Humans; Hydrocortisone; Mania; Purines; Uric Acid; Valproic Acid	2023
Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies. Neuropharmacology, 2020, 05-01, Volume: 167 Topics: Adenosine; Animals; Anticonvulsants; Diet, Ketogenic; DNA Methylation; Epigenesis, Genetic; Epilepsy; Histones; Humans	2020
Role of Adenosine Kinase Inhibitor in Adenosine Augmentation Therapy for Epilepsy: A Potential Novel Drug for Epilepsy. Current drug targets, 2020, Volume: 21, Issue:3 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Brain; Epilepsy; Humans; Mice; Protein Kinase Inhibitors	2020
RNA Editing in Neurological and Neurodegenerative Disorders. Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2181 Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Epilepsy; Humans; Inosine; Nervous System Diseases; Neurodegenerative Diseases; Phenotype; RNA Editing	2021
Adenosine-to-inosine RNA editing in neurological development and disease. RNA biology, 2021, Volume: 18, Issue:7 Topics: Adenosine; Amyotrophic Lateral Sclerosis; Astrocytoma; Bipolar Disorder; Central Nervous System Neoplasms; Epilepsy; Humans; Inosine; Kv1.1 Potassium Channel; MicroRNAs; Receptor, Serotonin, 5-HT2C; Receptors, AMPA; RNA Editing; Schizophrenia; Spasms, Infantile	2021
ATP and adenosine-Two players in the control of seizures and epilepsy development. Progress in neurobiology, 2021, Volume: 204 Topics: Adenosine; Adenosine Triphosphate; Epilepsy; Humans; Purines; Seizures	2021
The role of adenosine in epilepsy. Brain research bulletin, 2019, Volume: 151 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; DNA Methylation; Epigenesis, Genetic; Epilepsy; Humans; Receptor, Adenosine A1; Seizures	2019
[Angiotensins as neuromodulators]. Postepy biochemii, 2012, Volume: 58, Issue:4 Topics: Adenosine; Angiotensins; Animals; Brain; Epilepsy; gamma-Aminobutyric Acid; Humans; Neurons; Neurotransmitter Agents; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System	2012
Modulation of adenosinergic system and its application for the treatment of epilepsy. Pharmacological reports : PR, 2014, Volume: 66, Issue:3 Topics: Adenosine; Animals; Anticonvulsants; Epilepsy; Humans; Purinergic P1 Receptor Agonists	2014
Adenosinergic signaling in epilepsy. Neuropharmacology, 2016, Volume: 104 Topics: 5'-Nucleotidase; Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Epilepsy; Genetic Therapy; Homeostasis; Humans; Nucleoside Transport Proteins; Receptors, Purinergic P1; Signal Transduction	2016
From unwitnessed fatality to witnessed rescue: Pharmacologic intervention in sudden unexpected death in epilepsy. Epilepsia, 2016, Volume: 57 Suppl 1 Topics: Adenosine; Apnea; Brain Stem; Death, Sudden; Epilepsy; Humans; Hypoventilation; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Selective Serotonin Reuptake Inhibitors; Serotonin	2016
Role of the purinergic signaling in epilepsy. Pharmacological reports : PR, 2017, Volume: 69, Issue:1 Topics: Adenosine; Adenosine Kinase; Animals; Epilepsy; Humans; Purinergic P2X Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic; Receptors, Purinergic P2X7; Signal Transduction	2017
NTPDase and 5'-nucleotidase activities in physiological and disease conditions: new perspectives for human health. BioFactors (Oxford, England), 2007, Volume: 31, Issue:2 Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Atherosclerosis; Blood Coagulation; Blood Platelets; Cell Communication; Demyelinating Diseases; Epilepsy; Humans; Metabolism, Inborn Errors; Myocardial Infarction; Neoplasms; Platelet Activation; Platelet Aggregation; Seizures; Signal Transduction; Tamoxifen; Thrombosis	2007
Engineered adenosine-releasing cells for epilepsy therapy: human mesenchymal stem cells and human embryonic stem cells. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2009, Volume: 6, Issue:2 Topics: Adenosine; Animals; Embryonic Stem Cells; Epilepsy; Genetic Therapy; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells	2009
Adenosine augmentation therapies (AATs) for epilepsy: prospect of cell and gene therapies. Epilepsy research, 2009, Volume: 85, Issue:2-3 Topics: Adenosine; Animals; Anticonvulsants; Cell- and Tissue-Based Therapy; Drug Delivery Systems; Epilepsy; Genetic Therapy; Humans; Mice; Stem Cell Transplantation	2009
Therapeutic epilepsy research: from pharmacological rationale to focal adenosine augmentation. Biochemical pharmacology, 2009, Dec-15, Volume: 78, Issue:12 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; Drug Delivery Systems; Drug Implants; Epilepsy; Genetic Therapy; Humans; Mice; Neuroglia; Rats; Stem Cells	2009
The future of epilepsy treatment: focus on adeno-associated virus vector gene therapy. Drug news & perspectives, 2010, Volume: 23, Issue:5 Topics: Adenosine; Animals; Dependovirus; Epilepsy; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Neuropeptides	2010
Inhibitory RNA in epilepsy: research tools and therapeutic perspectives. Epilepsia, 2010, Volume: 51, Issue:9 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Brain; Epilepsy; Gene Expression Regulation; Genetic Therapy; Humans; Mice; MicroRNAs; RNA Interference	2010
Adenosine and ATP receptors in the brain. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:8 Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Dogs; Epilepsy; Female; Gene Expression; Humans; Ischemia; Mice; Neuralgia; Neuroglia; Neurons; Neurotransmitter Agents; Parkinson Disease; Rabbits; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2; Synaptic Transmission	2011
Modulators of nucleoside metabolism in the therapy of brain diseases. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:8 Topics: Adenosine; Adenosine Kinase; Analgesics; Animals; Anticonvulsants; Brain; Brain Diseases; Epilepsy; Gene Expression; Humans; Metabolic Networks and Pathways; Mice; Mice, Knockout; Neuroprotective Agents; Pain; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Schizophrenia; Signal Transduction; Sleep Wake Disorders	2011
Local delivery strategies in epilepsy: a focus on adenosine. Seizure, 2011, Volume: 20, Issue:5 Topics: Adenosine; Animals; Blood-Brain Barrier; Brain; Drug Delivery Systems; Epilepsy; Genetic Therapy; Humans	2011
Adenosine dysfunction in epilepsy. Glia, 2012, Volume: 60, Issue:8 Topics: Adenosine; Adenosine Kinase; Animals; Disease Models, Animal; Epilepsy; Humans; Metabolic Diseases; Phosphorylation	2012
[Adenosine and the anti-epileptic actions of ketogenic diets]. Zhonghua er ke za zhi = Chinese journal of pediatrics, 2012, Volume: 50, Issue:12 Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Brain; Diet, Carbohydrate-Restricted; Diet, Ketogenic; Energy Metabolism; Epilepsy; Humans	2012
Glial cell changes in epilepsy: overview of the clinical problem and therapeutic opportunities. Neurochemistry international, 2013, Volume: 63, Issue:7 Topics: Adenosine; Aquaporins; Calcium; Cell Transplantation; Epilepsy; Glucose; Humans; Neuroglia; Potassium Channels; Receptors, Glutamate	2013
Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2005, Volume: 11, Issue:1 Topics: Adenosine; Brain; Cell Transplantation; Epilepsy; Homeostasis; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Models, Neurological; Neural Inhibition; Nucleoside Transport Proteins; Purinergic P1 Receptor Agonists	2005
Modulatory role of adenosine and its receptors in epilepsy: possible therapeutic approaches. Neuroscience research, 2006, Volume: 56, Issue:1 Topics: Adenosine; Animals; Anticonvulsants; Epilepsy; Humans; Protein Isoforms; Receptors, Purinergic P1	2006
Adenosine kinase, epilepsy and stroke: mechanisms and therapies. Trends in pharmacological sciences, 2006, Volume: 27, Issue:12 Topics: Adenosine; Adenosine Kinase; Animals; Brain; Drug Delivery Systems; Enzyme Inhibitors; Epilepsy; Humans; Stroke	2006
Adenosine-based cell therapy approaches for pharmacoresistant epilepsies. Neuro-degenerative diseases, 2007, Volume: 4, Issue:1 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Cell- and Tissue-Based Therapy; Drug Tolerance; Epilepsy; Humans	2007
Adenosine as a neuromodulator in neurological diseases. Current opinion in pharmacology, 2008, Volume: 8, Issue:1 Topics: Adenosine; Adenosine Kinase; Alzheimer Disease; Animals; Brain Diseases; Brain Ischemia; Epilepsy; Humans; Huntington Disease; Pain; Parkinson Disease; Schizophrenia; Synaptic Transmission	2008
Adenine derivatives in epilepsy. Progress in clinical and biological research, 1980, Volume: 39 Topics: Adenine Nucleotides; Adenosine; Animals; Anticonvulsants; Cyclic AMP; Epilepsy; Hypoxanthines; Inosine; Mice; Ouabain; Rats; Veratridine	1980
Regulation of endogenous adenosine levels in the CNS: potential for therapy in stroke, epilepsy and pain. Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Adenosine; Animals; Central Nervous System; Central Nervous System Diseases; Cerebrovascular Disorders; Epilepsy; Homeostasis; Humans; Pain; Receptors, Purinergic P1	1994
Functions of neuronal adenosine receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 362, Issue:4-5 Topics: Adenosine; Animals; Calcium Channels; Epilepsy; Humans; Neurons; Neurotransmitter Agents; Potassium Channels; Receptors, Purinergic P1; Sleep	2000
The electrophysiology of adenosine in the mammalian central nervous system. Progress in neurobiology, 1991, Volume: 36, Issue:4 Topics: Adenosine; Animals; Calcium; Calcium Channels; Central Nervous System; Electrophysiology; Epilepsy; Evoked Potentials; Humans; Hypoxia; Ion Channel Gating; Mammals; Neurotransmitter Agents; Potassium; Potassium Channels; Second Messenger Systems; Synapses	1991
Adenosine receptors in brain: neuromodulation and role in epilepsy. Annals of neurology, 1989, Volume: 26, Issue:6 Topics: Adenosine; Anticonvulsants; Epilepsy; Humans; Receptors, Purinergic	1989
Purinergic mechanisms in epilepsy. Progress in neurobiology, 1988, Volume: 31, Issue:2 Topics: Adenosine; Animals; Epilepsy; Humans	1988

Trials

2 trial(s) available for adenosine and Epilepsy

Article	Year
Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial. Archives of medical research, 2007, Volume: 38, Issue:3 Topics: Adenosine; Adolescent; Adult; Allopurinol; Anticonvulsants; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Female; Humans; Male; Middle Aged; Placebos	2007
Is ACTH a key to understanding anticonvulsant action? Developmental medicine and child neurology, 1998, Volume: 40, Issue:2 Topics: Adenosine; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Binding Sites; Child; Child, Preschool; Cohort Studies; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Infant; Male; Receptors, GABA-A; Severity of Illness Index	1998

Article

Year

Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial.

Archives of medical research, 2007, Volume: 38, Issue:3

Topics: Adenosine; Adolescent; Adult; Allopurinol; Anticonvulsants; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Female; Humans; Male; Middle Aged; Placebos

2007

Is ACTH a key to understanding anticonvulsant action?

Developmental medicine and child neurology, 1998, Volume: 40, Issue:2

Topics: Adenosine; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Binding Sites; Child; Child, Preschool; Cohort Studies; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Infant; Male; Receptors, GABA-A; Severity of Illness Index

1998

Other Studies

75 other study(ies) available for adenosine and Epilepsy

Article	Year
A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer's model. JCI insight, 2022, 06-08, Volume: 7, Issue:11 Topics: Adenosine; Alzheimer Disease; Animals; Anticonvulsants; Epilepsy; Humans; Mice; Microfilament Proteins; Nerve Tissue Proteins; Receptor, Adenosine A1; RGS Proteins	2022
The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish. Neurochemical research, 2023, Volume: 48, Issue:6 Topics: Adenosine; Animals; Dipyridamole; Epilepsy; Pentylenetetrazole; Quality of Life; Seizures; Valproic Acid; Zebrafish	2023
Reactive A1 Astrocyte-Targeted Nucleic Acid Nanoantiepileptic Drug Downregulating Adenosine Kinase to Rescue Endogenous Antiepileptic Pathway. ACS applied materials & interfaces, 2023, Jun-28, Volume: 15, Issue:25 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Epilepsy; Mice; Nucleic Acids	2023
LncRNA CASC2 inhibits astrocytic activation and adenosine metabolism by regulating PTEN in pentylenetetrazol-induced epilepsy model. Journal of chemical neuroanatomy, 2020, Volume: 105 Topics: Adenosine; Animals; Astrocytes; Epilepsy; Hippocampus; Male; Pentylenetetrazole; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding	2020
Adenosine kinase deficiency: Three new cases and diagnostic value of hypermethioninemia. Molecular genetics and metabolism, 2021, Volume: 132, Issue:1 Topics: Adenosine; Adenosine Kinase; Amino Acid Metabolism, Inborn Errors; Child; Developmental Disabilities; Epilepsy; Female; Genetic Predisposition to Disease; Glycine N-Methyltransferase; Humans; Infant; Infant, Newborn; Liver Diseases; Male; Retrospective Studies	2021
Elevated blood purine levels as a biomarker of seizures and epilepsy. Epilepsia, 2021, Volume: 62, Issue:3 Topics: Adenosine; Adult; Animals; Biomarkers; Case-Control Studies; Epilepsy; Humans; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Point-of-Care Testing; Purines; Seizures; Severity of Illness Index; Status Epilepticus; Xanthine; Young Adult	2021
Astrocytes and Epilepsy. Neurochemical research, 2021, Volume: 46, Issue:10 Topics: Adenosine; Amino Acid Transport System X-AG; Animals; Aquaporin 4; Astrocytes; Epilepsy; Gap Junctions; Humans; Potassium Channels, Inwardly Rectifying	2021
[The 2-chloride adenosine alleviates the damage of brain tissues in pentylenetetrazole-kindled epileptic mice by regulating P-glycoprotein expression]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2017, Volume: 33, Issue:4 Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Epilepsy; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole	2017
Nitrobenzylthioinosine mimics adenosine to attenuate the epileptiform discharge of hippocampal neurons from epileptic rats. Oncotarget, 2017, May-30, Volume: 8, Issue:22 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Epilepsy; Gene Expression; Hippocampus; Male; Patch-Clamp Techniques; Protein Transport; Pyramidal Cells; Rats; Receptor, Adenosine A1; Thioinosine	2017
Transient Disruption of Adenosine Signaling During Embryogenesis Triggers a Pro-epileptic Phenotype in Adult Zebrafish. Molecular neurobiology, 2018, Volume: 55, Issue:8 Topics: Adenosine; Animals; Disease Susceptibility; Embryo, Nonmammalian; Embryonic Development; Epilepsy; Female; Fertilization; Larva; Male; Morpholinos; Motor Activity; Phenotype; Signal Transduction; Zebrafish	2018
Adenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders. Neurobiology of disease, 2018, Volume: 114 Topics: Adenosine; Animals; Comorbidity; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Organ Culture Techniques; Sleep Wake Disorders	2018
The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures. Journal of neurochemistry, 2018, Volume: 147, Issue:2 Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Creatine; Electrophysiological Phenomena; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Ribose; Seizures; Synaptic Transmission	2018
Early detonation by sprouted mossy fibers enables aberrant dentate network activity. Proceedings of the National Academy of Sciences of the United States of America, 2019, 05-28, Volume: 116, Issue:22 Topics: Adenosine; Animals; CA3 Region, Hippocampal; Dentate Gyrus; Disease Models, Animal; Epilepsy; Male; Mice; Mice, Transgenic; Mossy Fibers, Hippocampal; Optogenetics; Synapses	2019
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. The Journal of clinical investigation, 2013, Volume: 123, Issue:8 Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Azacitidine; Base Sequence; Brain; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Implants; Epigenesis, Genetic; Epilepsy; Male; Mice; Mossy Fibers, Hippocampal; Rats; Rats, Sprague-Dawley; Sequence Analysis, DNA	2013
Synthesis of a FTO inhibitor with anticonvulsant activity. ACS chemical neuroscience, 2014, Aug-20, Volume: 5, Issue:8 Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Anticonvulsants; Blotting, Western; Catalytic Domain; Disease Models, Animal; Epilepsy; HeLa Cells; Humans; Mice; MicroRNAs; Mixed Function Oxygenases; Models, Chemical; Molecular Structure; Oxo-Acid-Lyases; Proteins	2014
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats. Epilepsy research, 2016, Volume: 119 Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Genetic Predisposition to Disease; Incidence; Male; Oxygen; Rats; Respiration; Respiration Disorders; Seizures; Sex Characteristics; Tubercidin	2016
A pharmacodynamic analysis for the co-administration of inducers of CYP3A with ticagrelor: A cautionary tale in managing patients with acute coronary syndromes. International journal of cardiology, 2016, Jul-01, Volume: 214 Topics: Acute Coronary Syndrome; Adenosine; Aged; Aged, 80 and over; Anticonvulsants; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Administration Schedule; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Registries; Ticagrelor; Treatment Outcome	2016
Silk polymer-based adenosine release: therapeutic potential for epilepsy. Biomaterials, 2008, Volume: 29, Issue:26 Topics: Adenosine; Animals; Biocompatible Materials; Drug Carriers; Drug Delivery Systems; Epilepsy; Fibroins; Hippocampus; Humans; Kindling, Neurologic; Male; Materials Testing; Microspheres; Polymers; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Silk	2008
Quantification of levetiracetam in human plasma by liquid chromatography-tandem mass spectrometry: application to therapeutic drug monitoring. Journal of pharmaceutical and biomedical analysis, 2008, Nov-04, Volume: 48, Issue:3 Topics: Adenosine; Anticonvulsants; Calibration; Chromatography, Liquid; Drug Monitoring; Drug Stability; Drug Storage; Epilepsy; Freezing; Humans; Levetiracetam; Metabolic Clearance Rate; Piracetam; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Time Factors	2008
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors. Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-30, Volume: 105, Issue:39 Topics: Adenosine; Adenosine Deaminase; Adult; Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurons; Oocytes; Purinergic P1 Receptor Antagonists; Pyramidal Tracts; Pyrimidines; Quinazolines; Rats; Receptors, GABA-A; Triazoles; Xanthines; Xenopus	2008
Effects of progesterone on total brain tissue adenosine deaminase activity in experimental epilepsy. The International journal of neuroscience, 2009, Volume: 119, Issue:2 Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Convulsants; Disease Models, Animal; Epilepsy; Female; Male; Mice; Pentylenetetrazole; Polyunsaturated Alkamides; Progesterone; Propionates; Receptor, Adenosine A1; Receptors, GABA-A	2009
Antiepileptic effects of silk-polymer based adenosine release in kindled rats. Experimental neurology, 2009, Volume: 219, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anticonvulsants; Disease Models, Animal; Drug Delivery Systems; Drug Implants; Electric Stimulation; Epilepsy; Hippocampus; Kindling, Neurologic; Male; Polymers; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Silk; Treatment Outcome	2009
Adenosine A2A receptor deficient mice are partially resistant to limbic seizures. Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 380, Issue:3 Topics: Adenosine; Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Male; Mice; Mice, Knockout; Pentylenetetrazole; Pilocarpine; Receptor, Adenosine A2A; Seizures	2009
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance. Epilepsia, 2010, Volume: 51, Issue:3 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin	2010
Epileptogenic insult alters endogenous adenosine control on long-term changes in synaptic strength by theta pattern stimulation in hippocampus area CA1. Synapse (New York, N.Y.), 2011, Volume: 65, Issue:3 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Convulsants; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; Kindling, Neurologic; Male; Neuronal Plasticity; Organ Culture Techniques; Pentylenetetrazole; Rats; Seizures; Theta Rhythm	2011
Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery. Seizure, 2010, Volume: 19, Issue:7 Topics: Adenosine; Adenosine Kinase; Animals; Astrocytes; Blotting, Western; Cell Differentiation; Chromatography, Liquid; Epilepsy; Female; Fetal Stem Cells; Immunohistochemistry; Injections, Intraventricular; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Stem Cell Transplantation	2010
The interactions of nitric oxide and adenosine on penicillin-induced epileptiform activity in rats. Acta neurobiologiae experimentalis, 2011, Volume: 71, Issue:2 Topics: Action Potentials; Adenosine; Animals; Brain Waves; Disease Models, Animal; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Theophylline	2011
Endogenous adenosine induces NMDA receptor-independent persistent epileptiform discharges in dorsal and ventral hippocampus via activation of A2 receptors. Epilepsy research, 2012, Volume: 100, Issue:1-2 Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; Male; Rats; Rats, Wistar; Receptors, Adenosine A2; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials	2012
FTO, RNA epigenetics and epilepsy. Epigenetics, 2012, Volume: 7, Issue:10 Topics: 3' Untranslated Regions; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Central Nervous System; Epigenesis, Genetic; Epilepsy; Gene Expression Regulation; Humans; Methylation; MicroRNAs; Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcriptome	2012
Seizure suppression by adenosine-releasing cells is independent of seizure frequency. Epilepsia, 2002, Volume: 43, Issue:8 Topics: Adenosine; Animals; Capsules; Cell Survival; Cell Transplantation; Cerebral Ventricles; Cricetinae; Electroencephalography; Epilepsy; Kidney; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains	2002
Contribution of ionotropic glutamate receptors and voltage-dependent calcium channels to the potentiation phenomenon induced by transient pentylenetetrazol in the CA1 region of rat hippocampal slices. Brain research, 2003, Jan-03, Volume: 959, Issue:1 Topics: Adenosine; Animals; Calcium Channel Blockers; Calcium Channels; Epilepsy; Evoked Potentials; GABA Antagonists; Hippocampus; Long-Term Potentiation; Male; Neurotransmitter Agents; Organ Culture Techniques; Pentylenetetrazole; Rats; Receptors, AMPA; Receptors, Glutamate	2003
Changes in nucleotide hydrolysis in rat blood serum induced by pentylenetetrazol-kindling. Brain research. Molecular brain research, 2003, Jun-10, Volume: 114, Issue:2 Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Animals; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Epilepsy; Female; Hydrolysis; Kindling, Neurologic; Nucleotidases; Pentylenetetrazole; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission	2003
Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures. Epilepsy research, 2003, Volume: 55, Issue:3 Topics: Adenosine; Adolescent; Adult; Anticonvulsants; Aspartic Acid; Brain; Child; Cysts; Electroencephalography; Epilepsy; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Time Factors	2003
The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices. Anesthesia and analgesia, 2004, Volume: 99, Issue:4 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aminophylline; Anesthetics, Intravenous; Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theobromine; Xanthines	2004
Adenosine and ATP link PCO2 to cortical excitability via pH. Neuron, 2005, Dec-22, Volume: 48, Issue:6 Topics: Acids; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbon Dioxide; Epilepsy; Excitatory Postsynaptic Potentials; Extracellular Fluid; Hippocampus; Hydrogen-Ion Concentration; Hypercapnia; Hypocapnia; Membrane Potentials; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P2; Synaptic Transmission; Up-Regulation	2005
The support of adenosine release from adenosine kinase deficient ES cells by silk substrates. Biomaterials, 2006, Volume: 27, Issue:26 Topics: Adenosine; Adenosine Kinase; Animals; Biocompatible Materials; Capsules; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen Type I; Delayed-Action Preparations; Embryo, Mammalian; Epilepsy; Fibroins; Glucose; Hydrophobic and Hydrophilic Interactions; Mice; Mutation; Neuroglia; Peptides; Stem Cells	2006
Anticonvulsant effects of focal and intracerebroventricular adenosine on penicillin-induced epileptiform activity in rats. Brain research, 2007, Jan-05, Volume: 1127, Issue:1 Topics: Action Potentials; Adenosine; Animals; Anticonvulsants; Brain; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Penicillins; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline	2007
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants. Brain : a journal of neurology, 2007, Volume: 130, Issue:Pt 5 Topics: Adenosine; Adenosine Kinase; Animals; Brain; Cells, Cultured; Embryonic Stem Cells; Epilepsy; Genetic Engineering; Kindling, Neurologic; Male; Models, Animal; Paracrine Communication; Rats; Rats, Sprague-Dawley	2007
Brain methylation and epileptogenesis: the case of methionine sulfoximine. Annals of neurology, 1984, Volume: 16 Suppl Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine	1984
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy. European journal of pharmacology, 1994, Nov-24, Volume: 265, Issue:3 Topics: Adenosine; Animals; Aspartic Acid; Brain; Epilepsy; In Vitro Techniques; Kindling, Neurologic; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptosomes	1994
Epileptogenic actions of xanthines in relation to their affinities for adenosine A1 receptors in CA3 neurons of hippocampal slices (guinea pig). Brain research, 1994, Mar-21, Volume: 640, Issue:1-2 Topics: Adenosine; Animals; Caffeine; Calcium; Cyclic AMP; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Xanthines	1994
The effect of calcium removal on the suppression by adenosine of epileptiform activity in the hippocampus: demonstration of desensitization. British journal of pharmacology, 1994, Volume: 112, Issue:1 Topics: Adenosine; Animals; Baclofen; Calcium; Calcium-Transporting ATPases; Electric Stimulation; Epilepsy; Evoked Potentials; Hippocampus; Male; Purines; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Terpenes; Thapsigargin	1994
Characterization of adenosine receptor-mediated generation of cyclic AMP in slices of rat cerebral cortex with chronic epileptic activity. Neurochemical research, 1993, Volume: 18, Issue:9 Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Chronic Disease; Cyclic AMP; Electroencephalography; Epilepsy; Ferrous Compounds; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1	1993
Involvement of adenosine-sensitive cyclic AMP-generating systems in cobalt-induced epileptic activity in the rat. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Electroencephalography; Epilepsy; In Vitro Techniques; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Theophylline	1993
The adenosine binding enhancer, PD 81,723, inhibits epileptiform bursting in the hippocampal brain slice. Brain research, 1993, Aug-13, Volume: 619, Issue:1-2 Topics: Adenosine; Animals; Axons; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Pyramidal Tracts; Rats; Thiophenes	1993
Genetic variation in immediate and delayed postictal refractory period in rats. Brain research, 1996, May-20, Volume: 721, Issue:1-2 Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Epilepsy; Genetic Variation; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Species Specificity	1996
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices. British journal of pharmacology, 1998, Volume: 123, Issue:1 Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline	1998
Adenylosuccinase deficiency with neonatal onset severe epileptic seizures and sudden death. Neuropediatrics, 1998, Volume: 29, Issue:1 Topics: Adenosine; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Anticonvulsants; Death, Sudden; Epilepsy; Humans; Infant, Newborn; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Ribonucleotides	1998
Epileptiform activity in supragranular and infragranular blocks of mouse neocortex. Epilepsy research, 1998, Volume: 31, Issue:1 Topics: Adenosine; Animals; Culture Techniques; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Epilepsy; Evoked Potentials; Female; Magnesium Deficiency; Male; Mice; Mice, Inbred BALB C; Models, Biological; Neocortex; Osmolar Concentration; Perfusion; Somatosensory Cortex	1998
The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels. British journal of pharmacology, 1999, Volume: 128, Issue:5 Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anticonvulsants; Brain Chemistry; CHO Cells; Cricetinae; Electrophysiology; Enzyme Inhibitors; Epilepsy; Female; Hippocampus; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Triazoles	1999
Effects of an adenosine analogue administration on the striatal NMDA receptors in an experimental model of epilepsy. Neurochemistry international, 2000, Volume: 36, Issue:3 Topics: 3-Mercaptopropionic Acid; Adenosine; Animals; Cell Membrane; Convulsants; Corpus Striatum; Dizocilpine Maleate; Epilepsy; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tritium; Up-Regulation	2000
N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2000, Volume: 10, Issue:4 Topics: Adenosine; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Kindling, Neurologic; Male; Rats; Rats, Wistar; Theophylline; Valproic Acid	2000
Effects of postsynaptic GABA(B) receptor activation on epileptiform activity in hippocampal slices. Neuropharmacology, 2001, Volume: 40, Issue:1 Topics: Adenosine; Animals; Baclofen; Dentate Gyrus; Electrodes, Implanted; Epilepsy; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA-B Receptor Agonists; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Male; Potassium; Rats; Rats, Sprague-Dawley; Synapses	2001
K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection. Neuroscience, 2000, Volume: 100, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Cromakalim; Epilepsy; Hippocampus; HSP70 Heat-Shock Proteins; Male; Necrosis; Neuroprotective Agents; Phenylisopropyladenosine; Potassium Channels; Rats; Rats, Wistar; Signal Transduction; Stress, Physiological	2000
Effects of adenosine administration on spike-wave discharge frequency in genetically epileptic rats. Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:8 Topics: Adenosine; Animals; Disease Models, Animal; Electroencephalography; Epilepsy; Male; Rats	2001
Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptors. Brain research bulletin, 2001, Sep-15, Volume: 56, Issue:2 Topics: Adenosine; Angiotensin II; Angiotensin III; Angiotensins; Animals; Brain; Convulsants; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Kindling, Neurologic; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Seizures; Xanthines	2001
[Adenosine inhibits spontaneous and glutamate induced discharges of hippocampal CA1 neurons]. Sheng li xue bao : [Acta physiologica Sinica], 2000, Volume: 52, Issue:4 Topics: Adenosine; Animals; Electrophysiology; Epilepsy; Female; Glutamic Acid; Glyburide; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley	2000
Increased responses to adenosine and 2-chloroadenosine of cyclic AMP-generating systems in the primary cortical region of cobalt-induced epilepsy in the rat. The Japanese journal of physiology, 1992, Volume: 42, Issue:1 Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Epilepsy; Male; Rats; Rats, Inbred Strains	1992
Adenosine-mediated synaptic inhibition: partial blockade by barium does not prevent anti-epileptiform activity. Synapse (New York, N.Y.), 1992, Volume: 11, Issue:3 Topics: Action Potentials; Adenosine; Animals; Barium; Electrodes; Epilepsy; Evoked Potentials; Female; In Vitro Techniques; Male; Neurons; Potassium Channels; Rats; Synapses; Synaptic Transmission	1992
Depression of burst discharges and of neuronal calcium influx by adenosine. Epilepsy research. Supplement, 1992, Volume: 8 Topics: Adenosine; Animals; Calcium; Calcium Channels; Culture Techniques; Dendrites; Epilepsy; Hippocampus; Neural Inhibition; Neurons; Potassium; Potassium Channels; Protein Kinase C; Rats; Receptors, Purinergic; Synapses; Synaptic Membranes; Synaptic Transmission	1992
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex. Epilepsy research. Supplement, 1992, Volume: 8 Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate	1992
Adenosine: a potential mediator of seizure arrest and postictal refractoriness. Annals of neurology, 1992, Volume: 32, Issue:5 Topics: Adenosine; Adult; Brain Chemistry; Dialysis; Electroencephalography; Epilepsy; Female; Hippocampus; Humans; Male; Potassium	1992
Adenosine and seizure termination. Annals of neurology, 1991, Volume: 29, Issue:5 Topics: Adenosine; Epilepsy; Humans	1991
Influence of CGS 15943 A (a nonxanthine adenosine antagonist) on the protection offered by a variety of antiepileptic drugs against maximal electroshock-induced seizures in mice. Journal of neural transmission. General section, 1991, Volume: 86, Issue:2 Topics: Adenosine; Animals; Anticonvulsants; Disease Susceptibility; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Motor Activity; Quinazolines; Triazoles	1991
Alterations of A1 adenosine receptors in different mouse brain areas after pentylentetrazol-induced seizures, but not in the epileptic mutant mouse 'tottering'. Brain research, 1990, Nov-26, Volume: 534, Issue:1-2 Topics: Adenosine; Animals; Brain; Epilepsy; Kinetics; Mice; Mice, Inbred BALB C; Mice, Neurologic Mutants; Organ Specificity; Pentylenetetrazole; Receptors, Purinergic; Seizures; Species Specificity	1990
NMDA-receptor-independent effects of low magnesium: involvement of adenosine. Brain research, 1990, Feb-05, Volume: 508, Issue:2 Topics: Action Potentials; Adenosine; Animals; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Theophylline	1990
Regional difference in responsiveness of adenosine-sensitive cyclic AMP-generating systems in chronic epileptic cerebral cortex of the rat. Journal of neurochemistry, 1990, Volume: 55, Issue:4 Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Epilepsy; In Vitro Techniques; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline	1990
Endogenous adenosine can reduce epileptiform activity in the human epileptogenic cortex maintained in vitro. Neuroscience letters, 1989, Nov-20, Volume: 106, Issue:1-2 Topics: Adenosine; Cerebral Cortex; Epilepsy; Humans; In Vitro Techniques; Thioinosine	1989
Adenosine inhibits epileptiform activity arising in hippocampal area CA3. British journal of pharmacology, 1986, Volume: 87, Issue:4 Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Enzyme Induction; Epilepsy; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Purinergic; Synaptosomes; Theophylline	1986
Antiepileptic effects of N6-L-phenylisopropyladenosine (L-PIA) on penicillin-induced epileptogenic focus in rabbits. Pharmacological research communications, 1988, Volume: 20, Issue:7 Topics: Adenosine; Animals; Anticonvulsants; Electrodes, Implanted; Electroencephalography; Epilepsy; Male; Penicillins; Phenylisopropyladenosine; Rabbits	1988
The adenosine hypothesis of epilepsy. Medical hypotheses, 1988, Volume: 27, Issue:4 Topics: Adenosine; Animals; Anticonvulsants; Central Nervous System; Epilepsy; Humans; Models, Biological; Receptors, Purinergic	1988
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices. Brain research, 1988, Feb-16, Volume: 441, Issue:1-2 Topics: Adenosine; Animals; Caffeine; Calcium; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Nifedipine; Phenylisopropyladenosine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Verapamil	1988
Regulation of cerebral blood flow (CBF) during hypoxia and epileptic seizures. Advances in experimental medicine and biology, 1985, Volume: 191 Topics: 2-Chloroadenosine; Adenosine; Amobarbital; Animals; Cats; Cerebrovascular Circulation; Cyanides; Epilepsy; Hypoxia; Theophylline	1985
Protective effect of adenosine and nicotinamide against audiogenic seizure. Biochemical pharmacology, 1974, Oct-15, Volume: 23, Issue:20 Topics: Acoustic Stimulation; Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Brain Chemistry; Caffeine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred Strains; NAD; Niacinamide; Norepinephrine; Phosphocreatine; Phosphorus Radioisotopes; Time Factors	1974
Adenosine deaminase in cerebrospinal fluid. Enzymologia, 1972, Dec-31, Volume: 43, Issue:6 Topics: Adenosine; Adolescent; Adult; Aged; Aminohydrolases; Brain; Brain Neoplasms; Central Nervous System Diseases; Cerebellum; Cerebrospinal Fluid Proteins; Cerebrovascular Disorders; Child; Chlorides; Epilepsy; Female; Glioma; Glucose; Humans; Male; Meningioma; Meningitis; Middle Aged	1972