adenosine has been researched along with Epilepsy in 115 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (10.43) | 18.7374 |
1990's | 24 (20.87) | 18.2507 |
2000's | 33 (28.70) | 29.6817 |
2010's | 30 (26.09) | 24.3611 |
2020's | 16 (13.91) | 2.80 |
Authors | Studies |
---|---|
Guo, M; Li, T | 1 |
Chen, L; Chen, Y; Jiao, K; Law, WJ; McMahon, L; Pati, S; Pizarro, D; Saggu, S; Wang, Q | 1 |
Faingold, CL; Feng, HJ | 1 |
Bertoncello, KT; Bonan, CD | 1 |
Alves, M; Boison, D; Purnell, BS | 1 |
Cui, Y; Li, X; Lin, Y; Ma, W; Qiu, W; Wang, Q; Wang, Y; Wei, F; Xiong, H; Xu, R; Zhu, J | 1 |
Boison, D; Daniels, SD | 1 |
Boison, D; Rho, JM | 1 |
Li, T; Wang, X | 1 |
Chen, F; Liu, H; Luo, L; Ma, H; Qu, X; Xu, H; Yang, L; Zhang, R; Zhu, H | 1 |
Costa Cruz, PH; Kawahara, Y | 1 |
Becker, PH; Benoist, JF; Davit-Spraul, A; Demir, Z; Gaignard, P; Gonzales, E; Habes, D; Imbard, A; Jacquemin, E; Mozer Glassberg, Y; Mussini, C; Rozenfeld Bar Lev, M; Sevin, C; Slama, A; Thérond, P | 1 |
Okada, S; Sakurai, M; Yang, Y | 1 |
Alves, M; Beamer, E; Conte, G; Dale, N; de Diego-Garcia, L; Delanty, N; El-Naggar, H; Engel, T; Henshall, DC; Khalil, M; Lacey, A; Rosenow, F; Tian, F | 1 |
Binder, DK; Steinhäuser, C | 1 |
Beamer, E; Boison, D; Engel, T; Kuchukulla, M | 1 |
Gou, Y; Luo, L; Shan, P; Zhang, J; Zhu, S | 1 |
Huang, H; Li, D; Luo, Z; Peng, Y; Qiu, X; Wang, J; Xu, P; Xu, Z; Zhang, J | 1 |
da Silva, RS; Machado Torresini, F; Menezes, FP; Nery, LR | 1 |
Adamec, J; Grove, R; Madhavan, D; Roundtree, HM; Samson, KK; Simeone, KA; Simeone, TA; Smith, DD; Warren, TJ | 1 |
Frenguelli, BG; Hall, J | 1 |
Boison, D; Reemmer, J; Weltha, L | 1 |
Hendricks, WD; Schnell, E; Westbrook, GL | 1 |
Kowalski, A; Kuśmirowska, K; Rebas, E | 1 |
Boison, D; Farrell, JM; Kaplan, DL; Lusardi, TA; Lytle, NK; Pritchard, EM; Sandau, US; Williams-Karnesky, RL | 1 |
Bae, N; Booher, ME; Cox, T; Gabriel, GJ; He, C; Iacoban, P; Olsen, MJ; Rowles, J; Tribbey, L; Wang, GZ; Zheng, G; Zhou, L | 1 |
Kotowski, J; Świąder, MJ; Łuszczki, JJ | 1 |
Boison, D | 10 |
Faingold, CL; Kommajosyula, SP; Randall, ME | 1 |
Boison, D; Faingold, CL; Richerson, GB; Ryvlin, P | 1 |
Abunassar, J; Chong, AY; Hibbert, B; Le May, MR; Malhotra, N; Pourdjabbar, A; So, DY; Whitten, TA | 1 |
Cieślak, M; Komoszyński, M; Wojtczak, A | 1 |
Boison, D; Kaplan, DL; Lan, JQ; Li, T; Pritchard, EM; Wilz, A | 1 |
Matar, KM | 1 |
Bonan, CD; Morsch, VM; Schetinger, MR; Wyse, AT | 1 |
Arcella, A; Cantore, G; Di Gennaro, G; Esposito, V; Eusebi, F; Fredholm, BB; Fucile, S; Limatola, C; Manfredi, M; Martinello, K; Mascia, A; Miledi, R; Piccari, V; Quarato, PP; Roseti, C; Simonato, M | 1 |
Alptekin, M; Erkutlu, I; Kurtul, N; Pençe, S; Tan, U | 1 |
Boison, D; Kaplan, DL; Li, T; Lusardi, TA; Pritchard, EM; Szybala, C; Wilz, A | 1 |
Costentin, J; El Yacoubi, M; Ledent, C; Parmentier, M; Vaugeois, JM | 1 |
Boison, D; Li, T; Shen, HY | 1 |
Boison, D; Stewart, KA | 1 |
McCown, TJ | 1 |
Fathollahi, Y; Mirnajafizadeh, J; Salmani, ME; Semnanian, S | 1 |
Boison, D; Boon, P; Raedt, R; Theofilas, P; Van Dycke, A; Verstraete, A; Vonck, K; Wadman, W | 1 |
Burnstock, G; Fredholm, BB; Verkhratsky, A | 1 |
Boon, P; Raedt, R; Van Dycke, A; Vonck, K | 1 |
Ankarali, S; Ayyildiz, M; Marangoz, AH; Marangoz, C; Yildirim, M | 1 |
Kostopoulos, G; Moschovos, C; Papatheodoropoulos, C | 1 |
Olsen, M; Powers, R; Rowles, J; Wong, M | 1 |
Li, TF; Luan, GM | 1 |
Binder, DK; Fiacco, TA; Hsu, MS; Hubbard, JA | 1 |
Aebischer, P; Boison, D; Déglon, N; Huber, A; Möhler, H; Padrun, V | 1 |
Almasi, M; Fathollahi, Y; Firoozabadi, P; Mohammad, S; Omrani, A; Semnanian, S | 1 |
Amaral, O; Battastini, AM; Bonan, CD; Bruno, AN; Coitinho, A; Oses, JP; Sarkis, JJ | 1 |
Bernays, R; Blau, N; Boison, D; Imhof, HG; Rudolph, U; Wieser, HG; Yonekawa, Y | 1 |
Namiki, A; Ohmori, H; Sato, Y | 1 |
Dobelis, P; Dulla, CG; Frenguelli, BG; Masino, SA; Pearson, T; Staley, KJ | 1 |
Boison, D; Fedele, DE; Kaplan, DL; Meinel, L; Merkle, HP; Schumacher, C; Uebersax, L | 1 |
Asimakopoulos, B; Efthimiadou, A; Nikolettos, NK; Pagonopoulou, O | 1 |
Marangoz, C; Yildirim, M | 1 |
Ahmadi, B; Akhondzadeh, S; Motamedi, M; Razeghi, S; Togha, M | 1 |
Boison, D; Brüstle, O; Koch, P; Lan, JQ; Li, T; Lusardi, T; Segschneider, M; Simon, RP; Steinbeck, JA; Wilz, A | 1 |
Lewin, E | 1 |
Porta, R; Schatz, RA; Sellinger, OZ; Wilens, TE | 1 |
Foster, AC; Miller, LP; Wiesner, JB | 1 |
Beani, L; Bianchi, C; Borea, PA; Muzzolini, A; Simonato, M; Varani, K | 1 |
Bingmann, D; Moraidis, I | 1 |
Hosseinzadeh, H; Stone, TW | 1 |
Hattori, Y; Hayashi, Y; Hori, Y; Islam, N; Moriwaki, A | 1 |
Hattori, Y; Hayashi, Y; Hori, Y; Moriwaki, A | 1 |
Berman, RF; Janusz, CA | 1 |
Fochtmann, L; Francis, A | 1 |
Brodie, MJ; Ross, FM; Stone, TW | 1 |
Brown, JK; O'Regan, ME | 1 |
Bosschaart, AN; Duran, M; Hageman, G; Tien Poll-The, B; van den Bergh, FA | 1 |
Chesi, AJ; Stone, TW | 1 |
Dale, TJ; Dupere, JR; Starkey, SJ; Xie, X | 1 |
Giraldez, L; Girardi, E | 1 |
Borowicz, KK; Czuczwar, SJ; Kleinrok, Z | 1 |
Stringer, JL; Xiong, ZQ | 1 |
Blondeau, N; Heurteaux, C; Lazdunski, M; Plamondon, H; Richelme, C | 1 |
Haas, HL; Selbach, O | 1 |
Ates, N; Ilbay, G; Karson, A; Sahin, D | 1 |
Georgiev, V; Kambourova, T; Tchekalarova, J | 1 |
He, RR; Wang, H; Wang, ZA | 1 |
Hattori, Y; Hayashi, Y; Hori, Y; Lu, YF; Moriwaki, A | 1 |
Birnstiel, S; Gerber, U; Greene, RW | 1 |
Schubert, P | 1 |
Gale, K; Miller, LP; Murray, TF; Zhong, P | 1 |
During, MJ; Spencer, DD | 1 |
Greene, RW; Haas, HL | 1 |
Dragunow, M | 2 |
Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B | 1 |
Angelatou, F; Kostopoulos, G; Pagonopoulou, O | 1 |
Bartrup, JT; Connick, JH; Stone, TW | 1 |
Hattori, Y | 1 |
Avoli, M; Drapeau, C; Kostopoulos, G; Olivier, A; Villemeure, JG | 1 |
Chin, JH | 1 |
Ault, B; Wang, CM | 1 |
Caporali, MG; Niglio, T; Popoli, P; Scotti de Carolis, A | 1 |
O'Brien, DR | 1 |
Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A | 1 |
Dóra, E; Kovách, AG | 1 |
Chesielski, L; Kempf, E; Lehmann, A; Maitre, M; Mandel, P | 1 |
Hankiewicz, J; Lesniak, M | 1 |
38 review(s) available for adenosine and Epilepsy
Article | Year |
---|---|
Adenosine Dysfunction in Epilepsy and Associated Comorbidities.
Topics: Adenosine; Adenosine Kinase; Anticonvulsants; Epilepsy; Humans; Seizures | 2022 |
A unified hypothesis of SUDEP: Seizure-induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and other restorative respiratory response mechanisms mediated by the action of serotonin on the periaqu
Topics: Adenosine; Animals; Death, Sudden; Epilepsy; Humans; Periaqueductal Gray; Respiratory Insufficiency; Return of Spontaneous Circulation; Seizures; Serotonin; Sudden Unexpected Death in Epilepsy | 2023 |
Astrocyte-neuron circuits in epilepsy.
Topics: Adenosine; Astrocytes; Epilepsy; Glutamic Acid; Humans; Neurons | 2023 |
Bipolar mania and epilepsy pathophysiology and treatment may converge in purine metabolism: A new perspective on available evidence.
Topics: Adenosine; Adenosine Triphosphate; Antimanic Agents; Bipolar Disorder; Epilepsy; Humans; Hydrocortisone; Mania; Purines; Uric Acid; Valproic Acid | 2023 |
Epigenetics and epilepsy prevention: The therapeutic potential of adenosine and metabolic therapies.
Topics: Adenosine; Animals; Anticonvulsants; Diet, Ketogenic; DNA Methylation; Epigenesis, Genetic; Epilepsy; Histones; Humans | 2020 |
Role of Adenosine Kinase Inhibitor in Adenosine Augmentation Therapy for Epilepsy: A Potential Novel Drug for Epilepsy.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Brain; Epilepsy; Humans; Mice; Protein Kinase Inhibitors | 2020 |
RNA Editing in Neurological and Neurodegenerative Disorders.
Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Epilepsy; Humans; Inosine; Nervous System Diseases; Neurodegenerative Diseases; Phenotype; RNA Editing | 2021 |
Adenosine-to-inosine RNA editing in neurological development and disease.
Topics: Adenosine; Amyotrophic Lateral Sclerosis; Astrocytoma; Bipolar Disorder; Central Nervous System Neoplasms; Epilepsy; Humans; Inosine; Kv1.1 Potassium Channel; MicroRNAs; Receptor, Serotonin, 5-HT2C; Receptors, AMPA; RNA Editing; Schizophrenia; Spasms, Infantile | 2021 |
ATP and adenosine-Two players in the control of seizures and epilepsy development.
Topics: Adenosine; Adenosine Triphosphate; Epilepsy; Humans; Purines; Seizures | 2021 |
The role of adenosine in epilepsy.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; DNA Methylation; Epigenesis, Genetic; Epilepsy; Humans; Receptor, Adenosine A1; Seizures | 2019 |
[Angiotensins as neuromodulators].
Topics: Adenosine; Angiotensins; Animals; Brain; Epilepsy; gamma-Aminobutyric Acid; Humans; Neurons; Neurotransmitter Agents; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2012 |
Modulation of adenosinergic system and its application for the treatment of epilepsy.
Topics: Adenosine; Animals; Anticonvulsants; Epilepsy; Humans; Purinergic P1 Receptor Agonists | 2014 |
Adenosinergic signaling in epilepsy.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Epilepsy; Genetic Therapy; Homeostasis; Humans; Nucleoside Transport Proteins; Receptors, Purinergic P1; Signal Transduction | 2016 |
From unwitnessed fatality to witnessed rescue: Pharmacologic intervention in sudden unexpected death in epilepsy.
Topics: Adenosine; Apnea; Brain Stem; Death, Sudden; Epilepsy; Humans; Hypoventilation; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Selective Serotonin Reuptake Inhibitors; Serotonin | 2016 |
Role of the purinergic signaling in epilepsy.
Topics: Adenosine; Adenosine Kinase; Animals; Epilepsy; Humans; Purinergic P2X Receptor Antagonists; Receptor, Adenosine A2A; Receptors, Purinergic; Receptors, Purinergic P2X7; Signal Transduction | 2017 |
NTPDase and 5'-nucleotidase activities in physiological and disease conditions: new perspectives for human health.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Antigens, CD; Apyrase; Atherosclerosis; Blood Coagulation; Blood Platelets; Cell Communication; Demyelinating Diseases; Epilepsy; Humans; Metabolism, Inborn Errors; Myocardial Infarction; Neoplasms; Platelet Activation; Platelet Aggregation; Seizures; Signal Transduction; Tamoxifen; Thrombosis | 2007 |
Engineered adenosine-releasing cells for epilepsy therapy: human mesenchymal stem cells and human embryonic stem cells.
Topics: Adenosine; Animals; Embryonic Stem Cells; Epilepsy; Genetic Therapy; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells | 2009 |
Adenosine augmentation therapies (AATs) for epilepsy: prospect of cell and gene therapies.
Topics: Adenosine; Animals; Anticonvulsants; Cell- and Tissue-Based Therapy; Drug Delivery Systems; Epilepsy; Genetic Therapy; Humans; Mice; Stem Cell Transplantation | 2009 |
Therapeutic epilepsy research: from pharmacological rationale to focal adenosine augmentation.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; Drug Delivery Systems; Drug Implants; Epilepsy; Genetic Therapy; Humans; Mice; Neuroglia; Rats; Stem Cells | 2009 |
The future of epilepsy treatment: focus on adeno-associated virus vector gene therapy.
Topics: Adenosine; Animals; Dependovirus; Epilepsy; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Neuropeptides | 2010 |
Inhibitory RNA in epilepsy: research tools and therapeutic perspectives.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Brain; Epilepsy; Gene Expression Regulation; Genetic Therapy; Humans; Mice; MicroRNAs; RNA Interference | 2010 |
Adenosine and ATP receptors in the brain.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Dogs; Epilepsy; Female; Gene Expression; Humans; Ischemia; Mice; Neuralgia; Neuroglia; Neurons; Neurotransmitter Agents; Parkinson Disease; Rabbits; Rats; Receptors, Purinergic P1; Receptors, Purinergic P2; Synaptic Transmission | 2011 |
Modulators of nucleoside metabolism in the therapy of brain diseases.
Topics: Adenosine; Adenosine Kinase; Analgesics; Animals; Anticonvulsants; Brain; Brain Diseases; Epilepsy; Gene Expression; Humans; Metabolic Networks and Pathways; Mice; Mice, Knockout; Neuroprotective Agents; Pain; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A1; Receptor, Adenosine A2A; Schizophrenia; Signal Transduction; Sleep Wake Disorders | 2011 |
Local delivery strategies in epilepsy: a focus on adenosine.
Topics: Adenosine; Animals; Blood-Brain Barrier; Brain; Drug Delivery Systems; Epilepsy; Genetic Therapy; Humans | 2011 |
Adenosine dysfunction in epilepsy.
Topics: Adenosine; Adenosine Kinase; Animals; Disease Models, Animal; Epilepsy; Humans; Metabolic Diseases; Phosphorylation | 2012 |
[Adenosine and the anti-epileptic actions of ketogenic diets].
Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Brain; Diet, Carbohydrate-Restricted; Diet, Ketogenic; Energy Metabolism; Epilepsy; Humans | 2012 |
Glial cell changes in epilepsy: overview of the clinical problem and therapeutic opportunities.
Topics: Adenosine; Aquaporins; Calcium; Cell Transplantation; Epilepsy; Glucose; Humans; Neuroglia; Potassium Channels; Receptors, Glutamate | 2013 |
Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies.
Topics: Adenosine; Brain; Cell Transplantation; Epilepsy; Homeostasis; Humans; Membrane Transport Modulators; Membrane Transport Proteins; Models, Neurological; Neural Inhibition; Nucleoside Transport Proteins; Purinergic P1 Receptor Agonists | 2005 |
Modulatory role of adenosine and its receptors in epilepsy: possible therapeutic approaches.
Topics: Adenosine; Animals; Anticonvulsants; Epilepsy; Humans; Protein Isoforms; Receptors, Purinergic P1 | 2006 |
Adenosine kinase, epilepsy and stroke: mechanisms and therapies.
Topics: Adenosine; Adenosine Kinase; Animals; Brain; Drug Delivery Systems; Enzyme Inhibitors; Epilepsy; Humans; Stroke | 2006 |
Adenosine-based cell therapy approaches for pharmacoresistant epilepsies.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Cell- and Tissue-Based Therapy; Drug Tolerance; Epilepsy; Humans | 2007 |
Adenosine as a neuromodulator in neurological diseases.
Topics: Adenosine; Adenosine Kinase; Alzheimer Disease; Animals; Brain Diseases; Brain Ischemia; Epilepsy; Humans; Huntington Disease; Pain; Parkinson Disease; Schizophrenia; Synaptic Transmission | 2008 |
Adenine derivatives in epilepsy.
Topics: Adenine Nucleotides; Adenosine; Animals; Anticonvulsants; Cyclic AMP; Epilepsy; Hypoxanthines; Inosine; Mice; Ouabain; Rats; Veratridine | 1980 |
Regulation of endogenous adenosine levels in the CNS: potential for therapy in stroke, epilepsy and pain.
Topics: Adenosine; Animals; Central Nervous System; Central Nervous System Diseases; Cerebrovascular Disorders; Epilepsy; Homeostasis; Humans; Pain; Receptors, Purinergic P1 | 1994 |
Functions of neuronal adenosine receptors.
Topics: Adenosine; Animals; Calcium Channels; Epilepsy; Humans; Neurons; Neurotransmitter Agents; Potassium Channels; Receptors, Purinergic P1; Sleep | 2000 |
The electrophysiology of adenosine in the mammalian central nervous system.
Topics: Adenosine; Animals; Calcium; Calcium Channels; Central Nervous System; Electrophysiology; Epilepsy; Evoked Potentials; Humans; Hypoxia; Ion Channel Gating; Mammals; Neurotransmitter Agents; Potassium; Potassium Channels; Second Messenger Systems; Synapses | 1991 |
Adenosine receptors in brain: neuromodulation and role in epilepsy.
Topics: Adenosine; Anticonvulsants; Epilepsy; Humans; Receptors, Purinergic | 1989 |
Purinergic mechanisms in epilepsy.
Topics: Adenosine; Animals; Epilepsy; Humans | 1988 |
2 trial(s) available for adenosine and Epilepsy
Article | Year |
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Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial.
Topics: Adenosine; Adolescent; Adult; Allopurinol; Anticonvulsants; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Epilepsy; Female; Humans; Male; Middle Aged; Placebos | 2007 |
Is ACTH a key to understanding anticonvulsant action?
Topics: Adenosine; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Binding Sites; Child; Child, Preschool; Cohort Studies; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Humans; Infant; Male; Receptors, GABA-A; Severity of Illness Index | 1998 |
75 other study(ies) available for adenosine and Epilepsy
Article | Year |
---|---|
A peptide blocking the ADORA1-neurabin interaction is anticonvulsant and inhibits epilepsy in an Alzheimer's model.
Topics: Adenosine; Alzheimer Disease; Animals; Anticonvulsants; Epilepsy; Humans; Mice; Microfilament Proteins; Nerve Tissue Proteins; Receptor, Adenosine A1; RGS Proteins | 2022 |
The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish.
Topics: Adenosine; Animals; Dipyridamole; Epilepsy; Pentylenetetrazole; Quality of Life; Seizures; Valproic Acid; Zebrafish | 2023 |
Reactive A1 Astrocyte-Targeted Nucleic Acid Nanoantiepileptic Drug Downregulating Adenosine Kinase to Rescue Endogenous Antiepileptic Pathway.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Epilepsy; Mice; Nucleic Acids | 2023 |
LncRNA CASC2 inhibits astrocytic activation and adenosine metabolism by regulating PTEN in pentylenetetrazol-induced epilepsy model.
Topics: Adenosine; Animals; Astrocytes; Epilepsy; Hippocampus; Male; Pentylenetetrazole; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; RNA, Long Noncoding | 2020 |
Adenosine kinase deficiency: Three new cases and diagnostic value of hypermethioninemia.
Topics: Adenosine; Adenosine Kinase; Amino Acid Metabolism, Inborn Errors; Child; Developmental Disabilities; Epilepsy; Female; Genetic Predisposition to Disease; Glycine N-Methyltransferase; Humans; Infant; Infant, Newborn; Liver Diseases; Male; Retrospective Studies | 2021 |
Elevated blood purine levels as a biomarker of seizures and epilepsy.
Topics: Adenosine; Adult; Animals; Biomarkers; Case-Control Studies; Epilepsy; Humans; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Middle Aged; Point-of-Care Testing; Purines; Seizures; Severity of Illness Index; Status Epilepticus; Xanthine; Young Adult | 2021 |
Astrocytes and Epilepsy.
Topics: Adenosine; Amino Acid Transport System X-AG; Animals; Aquaporin 4; Astrocytes; Epilepsy; Gap Junctions; Humans; Potassium Channels, Inwardly Rectifying | 2021 |
[The 2-chloride adenosine alleviates the damage of brain tissues in pentylenetetrazole-kindled epileptic mice by regulating P-glycoprotein expression].
Topics: Adenosine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Epilepsy; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Pentylenetetrazole | 2017 |
Nitrobenzylthioinosine mimics adenosine to attenuate the epileptiform discharge of hippocampal neurons from epileptic rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Epilepsy; Gene Expression; Hippocampus; Male; Patch-Clamp Techniques; Protein Transport; Pyramidal Cells; Rats; Receptor, Adenosine A1; Thioinosine | 2017 |
Transient Disruption of Adenosine Signaling During Embryogenesis Triggers a Pro-epileptic Phenotype in Adult Zebrafish.
Topics: Adenosine; Animals; Disease Susceptibility; Embryo, Nonmammalian; Embryonic Development; Epilepsy; Female; Fertilization; Larva; Male; Morpholinos; Motor Activity; Phenotype; Signal Transduction; Zebrafish | 2018 |
Adenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders.
Topics: Adenosine; Animals; Comorbidity; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Organ Culture Techniques; Sleep Wake Disorders | 2018 |
The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Creatine; Electrophysiological Phenomena; Epilepsy; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Ribose; Seizures; Synaptic Transmission | 2018 |
Early detonation by sprouted mossy fibers enables aberrant dentate network activity.
Topics: Adenosine; Animals; CA3 Region, Hippocampal; Dentate Gyrus; Disease Models, Animal; Epilepsy; Male; Mice; Mice, Transgenic; Mossy Fibers, Hippocampal; Optogenetics; Synapses | 2019 |
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis.
Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Azacitidine; Base Sequence; Brain; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Implants; Epigenesis, Genetic; Epilepsy; Male; Mice; Mossy Fibers, Hippocampal; Rats; Rats, Sprague-Dawley; Sequence Analysis, DNA | 2013 |
Synthesis of a FTO inhibitor with anticonvulsant activity.
Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Anticonvulsants; Blotting, Western; Catalytic Domain; Disease Models, Animal; Epilepsy; HeLa Cells; Humans; Mice; MicroRNAs; Mixed Function Oxygenases; Models, Chemical; Molecular Structure; Oxo-Acid-Lyases; Proteins | 2014 |
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats.
Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Genetic Predisposition to Disease; Incidence; Male; Oxygen; Rats; Respiration; Respiration Disorders; Seizures; Sex Characteristics; Tubercidin | 2016 |
A pharmacodynamic analysis for the co-administration of inducers of CYP3A with ticagrelor: A cautionary tale in managing patients with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Adenosine; Aged; Aged, 80 and over; Anticonvulsants; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Administration Schedule; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Registries; Ticagrelor; Treatment Outcome | 2016 |
Silk polymer-based adenosine release: therapeutic potential for epilepsy.
Topics: Adenosine; Animals; Biocompatible Materials; Drug Carriers; Drug Delivery Systems; Epilepsy; Fibroins; Hippocampus; Humans; Kindling, Neurologic; Male; Materials Testing; Microspheres; Polymers; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Silk | 2008 |
Quantification of levetiracetam in human plasma by liquid chromatography-tandem mass spectrometry: application to therapeutic drug monitoring.
Topics: Adenosine; Anticonvulsants; Calibration; Chromatography, Liquid; Drug Monitoring; Drug Stability; Drug Storage; Epilepsy; Freezing; Humans; Levetiracetam; Metabolic Clearance Rate; Piracetam; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Time Factors | 2008 |
Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.
Topics: Adenosine; Adenosine Deaminase; Adult; Animals; Anticonvulsants; Cerebral Cortex; Epilepsy; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Neurons; Oocytes; Purinergic P1 Receptor Antagonists; Pyramidal Tracts; Pyrimidines; Quinazolines; Rats; Receptors, GABA-A; Triazoles; Xanthines; Xenopus | 2008 |
Effects of progesterone on total brain tissue adenosine deaminase activity in experimental epilepsy.
Topics: Adenosine; Adenosine Deaminase; Animals; Brain; Convulsants; Disease Models, Animal; Epilepsy; Female; Male; Mice; Pentylenetetrazole; Polyunsaturated Alkamides; Progesterone; Propionates; Receptor, Adenosine A1; Receptors, GABA-A | 2009 |
Antiepileptic effects of silk-polymer based adenosine release in kindled rats.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anticonvulsants; Disease Models, Animal; Drug Delivery Systems; Drug Implants; Electric Stimulation; Epilepsy; Hippocampus; Kindling, Neurologic; Male; Polymers; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Silk; Treatment Outcome | 2009 |
Adenosine A2A receptor deficient mice are partially resistant to limbic seizures.
Topics: Adenosine; Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Male; Mice; Mice, Knockout; Pentylenetetrazole; Pilocarpine; Receptor, Adenosine A2A; Seizures | 2009 |
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin | 2010 |
Epileptogenic insult alters endogenous adenosine control on long-term changes in synaptic strength by theta pattern stimulation in hippocampus area CA1.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Convulsants; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; Kindling, Neurologic; Male; Neuronal Plasticity; Organ Culture Techniques; Pentylenetetrazole; Rats; Seizures; Theta Rhythm | 2011 |
Astrocytes derived from fetal neural progenitor cells as a novel source for therapeutic adenosine delivery.
Topics: Adenosine; Adenosine Kinase; Animals; Astrocytes; Blotting, Western; Cell Differentiation; Chromatography, Liquid; Epilepsy; Female; Fetal Stem Cells; Immunohistochemistry; Injections, Intraventricular; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymerase Chain Reaction; Stem Cell Transplantation | 2010 |
The interactions of nitric oxide and adenosine on penicillin-induced epileptiform activity in rats.
Topics: Action Potentials; Adenosine; Animals; Brain Waves; Disease Models, Animal; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Theophylline | 2011 |
Endogenous adenosine induces NMDA receptor-independent persistent epileptiform discharges in dorsal and ventral hippocampus via activation of A2 receptors.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Epilepsy; Excitatory Postsynaptic Potentials; Hippocampus; Male; Rats; Rats, Wistar; Receptors, Adenosine A2; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials | 2012 |
FTO, RNA epigenetics and epilepsy.
Topics: 3' Untranslated Regions; Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Central Nervous System; Epigenesis, Genetic; Epilepsy; Gene Expression Regulation; Humans; Methylation; MicroRNAs; Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcriptome | 2012 |
Seizure suppression by adenosine-releasing cells is independent of seizure frequency.
Topics: Adenosine; Animals; Capsules; Cell Survival; Cell Transplantation; Cerebral Ventricles; Cricetinae; Electroencephalography; Epilepsy; Kidney; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains | 2002 |
Contribution of ionotropic glutamate receptors and voltage-dependent calcium channels to the potentiation phenomenon induced by transient pentylenetetrazol in the CA1 region of rat hippocampal slices.
Topics: Adenosine; Animals; Calcium Channel Blockers; Calcium Channels; Epilepsy; Evoked Potentials; GABA Antagonists; Hippocampus; Long-Term Potentiation; Male; Neurotransmitter Agents; Organ Culture Techniques; Pentylenetetrazole; Rats; Receptors, AMPA; Receptors, Glutamate | 2003 |
Changes in nucleotide hydrolysis in rat blood serum induced by pentylenetetrazol-kindling.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Animals; Apyrase; Biomarkers; Brain; Convulsants; Disease Models, Animal; Epilepsy; Female; Hydrolysis; Kindling, Neurologic; Nucleotidases; Pentylenetetrazole; Presynaptic Terminals; Rats; Rats, Wistar; Synaptic Transmission | 2003 |
Amino acid composition of brain cysts: levels of excitatory amino acids in cyst fluid fail to predict seizures.
Topics: Adenosine; Adolescent; Adult; Anticonvulsants; Aspartic Acid; Brain; Child; Cysts; Electroencephalography; Epilepsy; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Male; Middle Aged; Time Factors | 2003 |
The anticonvulsant action of propofol on epileptiform activity in rat hippocampal slices.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Aminophylline; Anesthetics, Intravenous; Animals; Anticonvulsants; Bicuculline; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theobromine; Xanthines | 2004 |
Adenosine and ATP link PCO2 to cortical excitability via pH.
Topics: Acids; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Carbon Dioxide; Epilepsy; Excitatory Postsynaptic Potentials; Extracellular Fluid; Hippocampus; Hydrogen-Ion Concentration; Hypercapnia; Hypocapnia; Membrane Potentials; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Purinergic P2; Synaptic Transmission; Up-Regulation | 2005 |
The support of adenosine release from adenosine kinase deficient ES cells by silk substrates.
Topics: Adenosine; Adenosine Kinase; Animals; Biocompatible Materials; Capsules; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen Type I; Delayed-Action Preparations; Embryo, Mammalian; Epilepsy; Fibroins; Glucose; Hydrophobic and Hydrophilic Interactions; Mice; Mutation; Neuroglia; Peptides; Stem Cells | 2006 |
Anticonvulsant effects of focal and intracerebroventricular adenosine on penicillin-induced epileptiform activity in rats.
Topics: Action Potentials; Adenosine; Animals; Anticonvulsants; Brain; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Electroencephalography; Epilepsy; Female; Injections, Intraventricular; Penicillins; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2007 |
Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants.
Topics: Adenosine; Adenosine Kinase; Animals; Brain; Cells, Cultured; Embryonic Stem Cells; Epilepsy; Genetic Engineering; Kindling, Neurologic; Male; Models, Animal; Paracrine Communication; Rats; Rats, Sprague-Dawley | 2007 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine.
Topics: Adenosine; Animals; Brain; Epilepsy; Histamine; Homocysteine; Methionine; Methionine Sulfoximine; Methylation; Methylhistamines; Mice; Nerve Tissue Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine | 1984 |
Adenosine A1 receptors in the rat brain in the kindling model of epilepsy.
Topics: Adenosine; Animals; Aspartic Acid; Brain; Epilepsy; In Vitro Techniques; Kindling, Neurologic; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptosomes | 1994 |
Epileptogenic actions of xanthines in relation to their affinities for adenosine A1 receptors in CA3 neurons of hippocampal slices (guinea pig).
Topics: Adenosine; Animals; Caffeine; Calcium; Cyclic AMP; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Xanthines | 1994 |
The effect of calcium removal on the suppression by adenosine of epileptiform activity in the hippocampus: demonstration of desensitization.
Topics: Adenosine; Animals; Baclofen; Calcium; Calcium-Transporting ATPases; Electric Stimulation; Epilepsy; Evoked Potentials; Hippocampus; Male; Purines; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Terpenes; Thapsigargin | 1994 |
Characterization of adenosine receptor-mediated generation of cyclic AMP in slices of rat cerebral cortex with chronic epileptic activity.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Chronic Disease; Cyclic AMP; Electroencephalography; Epilepsy; Ferrous Compounds; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1 | 1993 |
Involvement of adenosine-sensitive cyclic AMP-generating systems in cobalt-induced epileptic activity in the rat.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Electroencephalography; Epilepsy; In Vitro Techniques; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Theophylline | 1993 |
The adenosine binding enhancer, PD 81,723, inhibits epileptiform bursting in the hippocampal brain slice.
Topics: Adenosine; Animals; Axons; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Pyramidal Tracts; Rats; Thiophenes | 1993 |
Genetic variation in immediate and delayed postictal refractory period in rats.
Topics: Adenosine; Animals; Caffeine; Central Nervous System Stimulants; Epilepsy; Genetic Variation; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Species Specificity | 1996 |
Modulation by adenine nucleotides of epileptiform activity in the CA3 region of rat hippocampal slices.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Electric Stimulation; Epilepsy; Hippocampus; In Vitro Techniques; Male; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Rats; Rats, Wistar; Suramin; Theophylline | 1998 |
Adenylosuccinase deficiency with neonatal onset severe epileptic seizures and sudden death.
Topics: Adenosine; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Anticonvulsants; Death, Sudden; Epilepsy; Humans; Infant, Newborn; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Ribonucleotides | 1998 |
Epileptiform activity in supragranular and infragranular blocks of mouse neocortex.
Topics: Adenosine; Animals; Culture Techniques; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Epilepsy; Evoked Potentials; Female; Magnesium Deficiency; Male; Mice; Mice, Inbred BALB C; Models, Biological; Neocortex; Osmolar Concentration; Perfusion; Somatosensory Cortex | 1998 |
The anticonvulsant BW534U87 depresses epileptiform activity in rat hippocampal slices by an adenosine-dependent mechanism and through inhibition of voltage-gated Na+ channels.
Topics: Action Potentials; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Anticonvulsants; Brain Chemistry; CHO Cells; Cricetinae; Electrophysiology; Enzyme Inhibitors; Epilepsy; Female; Hippocampus; In Vitro Techniques; Ion Channel Gating; Magnesium; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Sodium Channels; Triazoles | 1999 |
Effects of an adenosine analogue administration on the striatal NMDA receptors in an experimental model of epilepsy.
Topics: 3-Mercaptopropionic Acid; Adenosine; Animals; Cell Membrane; Convulsants; Corpus Striatum; Dizocilpine Maleate; Epilepsy; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tritium; Up-Regulation | 2000 |
N(6)-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive action of conventional antiepileptic drugs in the kindling model of epilepsy in rats.
Topics: Adenosine; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Kindling, Neurologic; Male; Rats; Rats, Wistar; Theophylline; Valproic Acid | 2000 |
Effects of postsynaptic GABA(B) receptor activation on epileptiform activity in hippocampal slices.
Topics: Adenosine; Animals; Baclofen; Dentate Gyrus; Electrodes, Implanted; Epilepsy; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA-B Receptor Agonists; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Male; Potassium; Rats; Rats, Sprague-Dawley; Synapses | 2001 |
K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection.
Topics: Adenosine; Adenosine Triphosphate; Animals; Apoptosis; Cromakalim; Epilepsy; Hippocampus; HSP70 Heat-Shock Proteins; Male; Necrosis; Neuroprotective Agents; Phenylisopropyladenosine; Potassium Channels; Rats; Rats, Wistar; Signal Transduction; Stress, Physiological | 2000 |
Effects of adenosine administration on spike-wave discharge frequency in genetically epileptic rats.
Topics: Adenosine; Animals; Disease Models, Animal; Electroencephalography; Epilepsy; Male; Rats | 2001 |
Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptors.
Topics: Adenosine; Angiotensin II; Angiotensin III; Angiotensins; Animals; Brain; Convulsants; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Kindling, Neurologic; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Seizures; Xanthines | 2001 |
[Adenosine inhibits spontaneous and glutamate induced discharges of hippocampal CA1 neurons].
Topics: Adenosine; Animals; Electrophysiology; Epilepsy; Female; Glutamic Acid; Glyburide; Hippocampus; In Vitro Techniques; Male; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley | 2000 |
Increased responses to adenosine and 2-chloroadenosine of cyclic AMP-generating systems in the primary cortical region of cobalt-induced epilepsy in the rat.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Epilepsy; Male; Rats; Rats, Inbred Strains | 1992 |
Adenosine-mediated synaptic inhibition: partial blockade by barium does not prevent anti-epileptiform activity.
Topics: Action Potentials; Adenosine; Animals; Barium; Electrodes; Epilepsy; Evoked Potentials; Female; In Vitro Techniques; Male; Neurons; Potassium Channels; Rats; Synapses; Synaptic Transmission | 1992 |
Depression of burst discharges and of neuronal calcium influx by adenosine.
Topics: Adenosine; Animals; Calcium; Calcium Channels; Culture Techniques; Dendrites; Epilepsy; Hippocampus; Neural Inhibition; Neurons; Potassium; Potassium Channels; Protein Kinase C; Rats; Receptors, Purinergic; Synapses; Synaptic Membranes; Synaptic Transmission | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Amygdala; Animals; Bicuculline; Brain Mapping; Carbachol; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Ibotenic Acid; Kainic Acid; Limbic System; Muscimol; Quisqualic Acid; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Adenosine: a potential mediator of seizure arrest and postictal refractoriness.
Topics: Adenosine; Adult; Brain Chemistry; Dialysis; Electroencephalography; Epilepsy; Female; Hippocampus; Humans; Male; Potassium | 1992 |
Adenosine and seizure termination.
Topics: Adenosine; Epilepsy; Humans | 1991 |
Influence of CGS 15943 A (a nonxanthine adenosine antagonist) on the protection offered by a variety of antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Adenosine; Animals; Anticonvulsants; Disease Susceptibility; Drug Interactions; Electroshock; Epilepsy; Male; Mice; Motor Activity; Quinazolines; Triazoles | 1991 |
Alterations of A1 adenosine receptors in different mouse brain areas after pentylentetrazol-induced seizures, but not in the epileptic mutant mouse 'tottering'.
Topics: Adenosine; Animals; Brain; Epilepsy; Kinetics; Mice; Mice, Inbred BALB C; Mice, Neurologic Mutants; Organ Specificity; Pentylenetetrazole; Receptors, Purinergic; Seizures; Species Specificity | 1990 |
NMDA-receptor-independent effects of low magnesium: involvement of adenosine.
Topics: Action Potentials; Adenosine; Animals; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Theophylline | 1990 |
Regional difference in responsiveness of adenosine-sensitive cyclic AMP-generating systems in chronic epileptic cerebral cortex of the rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Epilepsy; In Vitro Techniques; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Endogenous adenosine can reduce epileptiform activity in the human epileptogenic cortex maintained in vitro.
Topics: Adenosine; Cerebral Cortex; Epilepsy; Humans; In Vitro Techniques; Thioinosine | 1989 |
Adenosine inhibits epileptiform activity arising in hippocampal area CA3.
Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Enzyme Induction; Epilepsy; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Purinergic; Synaptosomes; Theophylline | 1986 |
Antiepileptic effects of N6-L-phenylisopropyladenosine (L-PIA) on penicillin-induced epileptogenic focus in rabbits.
Topics: Adenosine; Animals; Anticonvulsants; Electrodes, Implanted; Electroencephalography; Epilepsy; Male; Penicillins; Phenylisopropyladenosine; Rabbits | 1988 |
The adenosine hypothesis of epilepsy.
Topics: Adenosine; Animals; Anticonvulsants; Central Nervous System; Epilepsy; Humans; Models, Biological; Receptors, Purinergic | 1988 |
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices.
Topics: Adenosine; Animals; Caffeine; Calcium; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Nifedipine; Phenylisopropyladenosine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Regulation of cerebral blood flow (CBF) during hypoxia and epileptic seizures.
Topics: 2-Chloroadenosine; Adenosine; Amobarbital; Animals; Cats; Cerebrovascular Circulation; Cyanides; Epilepsy; Hypoxia; Theophylline | 1985 |
Protective effect of adenosine and nicotinamide against audiogenic seizure.
Topics: Acoustic Stimulation; Adenosine; Adenosine Triphosphate; Animals; Blood Pressure; Brain Chemistry; Caffeine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Mice; Mice, Inbred Strains; NAD; Niacinamide; Norepinephrine; Phosphocreatine; Phosphorus Radioisotopes; Time Factors | 1974 |
Adenosine deaminase in cerebrospinal fluid.
Topics: Adenosine; Adolescent; Adult; Aged; Aminohydrolases; Brain; Brain Neoplasms; Central Nervous System Diseases; Cerebellum; Cerebrospinal Fluid Proteins; Cerebrovascular Disorders; Child; Chlorides; Epilepsy; Female; Glioma; Glucose; Humans; Male; Meningioma; Meningitis; Middle Aged | 1972 |