2-amino-4-phosphonobutyric acid has been researched along with Epilepsy in 6 studies
2-amino-4-phosphonobutyric acid: glutamate antagonist in locust muscle; structure; do not confuse with L-AP4, which is the propionic acid version
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maciejak, P | 1 |
| Szyndler, J | 1 |
| Turzyńska, D | 1 |
| Sobolewska, A | 1 |
| Taracha, E | 1 |
| Skórzewska, A | 1 |
| Lehner, M | 1 |
| Bidziński, A | 1 |
| Hamed, A | 1 |
| Wisłowska-Stanek, A | 1 |
| Płaźnik, A | 1 |
| Peterson, DW | 1 |
| Collins, JF | 2 |
| Bradford, HF | 3 |
| Coutinho-Netto, J | 1 |
| Abdul-Ghani, AS | 2 |
| Burke, JP | 1 |
| Hablitz, JJ | 1 |
| Attwell, PJ | 1 |
| Singh Kent, N | 1 |
| Croucher, MJ | 1 |
| Jane, DE | 1 |
| Neugebauer, V | 1 |
| Keele, NB | 1 |
| Shinnick-Gallagher, P | 1 |
6 other studies available for 2-amino-4-phosphonobutyric acid and Epilepsy
| Article | Year |
|---|---|
The effects of group III mGluR ligands on pentylenetetrazol-induced kindling of seizures and hippocampal amino acids concentration.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Convulsants; Disease Models, Animal; Dose-Response Re | 2009 |
The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Amygdala; Animals; Anticonvulsants; Epilep | 1983 |
Is glutamate a trigger factor in epileptic hyperactivity?
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Cerebral Cortex; Electroencephalography; Epilep | 1981 |
Metabotropic glutamate receptor activation decreases epileptiform activity in rat neocortex.
Topics: Aminobutyrates; Animals; Bicuculline; Cerebral Cortex; Cycloleucine; Epilepsy; Evoked Potentials; Fe | 1994 |
Anti-epileptogenic and anticonvulsant activity of L-2-amino-4-phosphonobutyrate, a presynaptic glutamate receptor agonist.
Topics: Alanine; Aminobutyrates; Amygdala; Analysis of Variance; Animals; Anticonvulsants; Calcium Radioisot | 1997 |
Loss of long-lasting potentiation mediated by group III mGluRs in amygdala neurons in kindling-induced epileptogenesis.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Amygdala; Animals; Epilepsy; Excitatory Amino Acid Agonis | 1997 |