Compounds > chloroquine diorotate
Page last updated: 2024-11-06

chloroquine diorotate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID83835
MeSH IDM0040743

Synonyms (16)

Synonym
16301-30-7
kidola
1,4-pentanediamine, n4-(7-chloro-4-quinolinyl)-n1,n1-diethyl-, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylate)
kidora
quinoline, 7-chloro-4-((4-(diethylamino)-1-methylbutyl)amino)-, orotate (1:2)
einecs 240-389-6
1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid, compoundwith n4-(7-chloro-4-quinolyl)-n1,n1-diethylpentane-1,4-diamine (2 :1)
chloroquine diorotate
1ro28ba0do ,
unii-1ro28ba0do
chloroquine diorotate [who-dd]
4-n-(7-chloroquinolin-4-yl)-1-n,1-n-diethylpentane-1,4-diamine;2,4-dioxo-1h-pyrimidine-6-carboxylic acid
DTXSID00936779
2,6-dihydroxypyrimidine-4-carboxylic acid--n~4~-(7-chloroquinolin-4-yl)-n~1~,n~1~-diethylpentane-1,4-diamine (2/1)
Q27252807
1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid,compound with n4-(7-chloro-4-quinolyl)-n1,n1-diethylpentane-1,4-diamine(2:1)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
orotic acid
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.. orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.		2.6330pyrimidinemonocarboxylic acidEscherichia coli metabolite;
metabolite;
mouse metabolite
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.		3.0350aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
ConditionIndicatedRelationship StrengthStudiesTrials
Edema-Proteinuria-Hypertension Gestosis
[description not available]		01.9310
Pre-Eclampsia
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.		01.9310
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		06.9310
Proteinuria
The presence of proteins in the urine, an indicator of KIDNEY DISEASES.		07.3420
Toxemia
A condition produced by the presence of toxins or other harmful substances in the BLOOD.		06.9310
Aura
[description not available]		01.9310
Epilepsy
A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)		01.9310
Dermatoses
[description not available]		02.3420
Skin Diseases
Diseases involving the DERMIS or EPIDERMIS.		02.3420
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues.		01.9310