mianserin has been researched along with Epilepsy in 9 studies
Mianserin: A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
mianserin : A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effects of the noradrenergic and specific serotonergic antidepressant mirtazapine on motor cortex excitability in epilepsy patients with depression and in healthy controls, using transcranial magnetic stimulation (TMS)." | 7.73 | Mirtazapine increases cortical excitability in healthy controls and epilepsy patients with major depression. ( Gerschlager, W; Langosch, JM; Münchau, A; Orth, M; Rothwell, JC; Trimble, MR, 2005) |
| "To examine the effects of the noradrenergic and specific serotonergic antidepressant mirtazapine on motor cortex excitability in epilepsy patients with depression and in healthy controls, using transcranial magnetic stimulation (TMS)." | 3.73 | Mirtazapine increases cortical excitability in healthy controls and epilepsy patients with major depression. ( Gerschlager, W; Langosch, JM; Münchau, A; Orth, M; Rothwell, JC; Trimble, MR, 2005) |
| "On the average, seizures were observed at 40 mg/kg and were seen after desmethylimipramine (50 mg/kg), mianserin (30 mg/kg), amitriptyline (20 mg/kg), imipramine (40 mg/kg), maprotiline (40 mg/kg), and zimelidine (50 mg/kg)." | 1.27 | Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. ( Bradford, D; Krijzer, F; Snelder, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Juckel, G | 2 |
| Schüle, C | 1 |
| Pogarell, O | 2 |
| Rupp, D | 1 |
| Laakmann, G | 1 |
| Hegerl, U | 2 |
| Münchau, A | 1 |
| Langosch, JM | 1 |
| Gerschlager, W | 1 |
| Rothwell, JC | 1 |
| Orth, M | 1 |
| Trimble, MR | 1 |
| Sterr, A | 1 |
| Padberg, F | 1 |
| Amann, B | 1 |
| Mergl, R | 1 |
| Mulert, C | 1 |
| Krijzer, F | 1 |
| Snelder, M | 1 |
| Bradford, D | 1 |
| Sedgwick, EM | 1 |
| Edwards, JG | 1 |
| Evans, L | 1 |
| Lander, CM | 1 |
| Mikhail, WI | 1 |
| Koponen, H | 2 |
| Honkonen, S | 2 |
| Partanen, J | 2 |
| Riekkinen, PJ | 2 |
1 trial available for mianserin and Epilepsy
| Article | Year |
|---|---|
Mianserin, maprotiline and the electroencephalogram.
Topics: Adult; Anthracenes; Dibenzazepines; Electroencephalography; Epilepsy; Female; Humans; Male; Maprotil | 1983 |
8 other studies available for mianserin and Epilepsy
| Article | Year |
|---|---|
Epileptiform EEG patterns induced by mirtazapine in both psychiatric patients and healthy volunteers.
Topics: Adult; Antidepressive Agents; Electroencephalography; Epilepsy; Female; Humans; Mental Disorders; Mi | 2003 |
Mirtazapine increases cortical excitability in healthy controls and epilepsy patients with major depression.
Topics: Adult; Antidepressive Agents, Tricyclic; Arousal; Depressive Disorder, Major; Electric Stimulation; | 2005 |
Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline.
Topics: Adult; Amitriptyline; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Electroence | 2006 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Re | 1984 |
Mianserin and epilepsy.
Topics: Adult; Depressive Disorder; Dibenzazepines; Epilepsy; Humans; Male; Mianserin; Phenytoin; Seizures | 1980 |
Epileptogenic effect of mianserin.
Topics: Adult; Convulsants; Dibenzazepines; Epilepsy; Female; Humans; Mianserin | 1979 |
[Symptoms of Creutzfeldt-Jakob disease during mianserin therapy].
Topics: Aged; Creutzfeldt-Jakob Syndrome; Depression; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Male | 1991 |
Epileptic attack, delirium, and periodic complexes in the EEG during mianserin treatment.
Topics: Aged; Creutzfeldt-Jakob Syndrome; Delirium; Depressive Disorder; Diagnosis, Differential; Electroenc | 1991 |