thyroxine has been researched along with Epilepsy in 60 studies
Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to evaluate thyroid function in 78 girls taking carbamazepine (CBZ), oxcarbazepine (OXC), or valproate (VPA) monotherapy for epilepsy and after withdrawal of the treatment." | 9.11 | Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after withdrawal of medication. ( Isojärvi, JI; Knip, M; Mikkonen, K; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Vainionpää, LK, 2004) |
| " Therefore, we conducted a prospective longitudinal study to evaluate the effects of LEV and carbamazepine (CBZ) treatment on lipid profile and thyroid hormone levels in patients newly diagnosed with epilepsy." | 7.91 | Lipid and thyroid hormone levels in children with epilepsy treated with levetiracetam or carbamazepine: A prospective observational study. ( Iijima, K; Ishida, Y; Maruyama, A; Nagase, H; Nakagawa, T; Nishimura, N; Nishiyama, M; Nozu, K; Takami, Y; Tanaka, T; Tokumoto, S; Tomioka, K; Toyoshima, D; Yamaguchi, H, 2019) |
| " He had been administered phenytoin and gabapentin for the treatment of symptomatic traumatic epilepsy 8 years before." | 7.88 | Hypothyroidism induced by phenytoin and gabapentin: A Case Report. ( Ishii, K; Miyake, Z; Tamaoka, A, 2018) |
| "The aim of this study was to evaluate the incidence of thyroid dysfunction during valproic acid (VPA) therapy in children and adolescents with epilepsy." | 7.78 | Subclinical hypothyroidism during valproic acid therapy in children and adolescents with epilepsy. ( Chae, JH; Chung, HR; Hwang, H; Hwang, YS; Kim, H; Kim, KJ; Kim, SH; Lim, BC, 2012) |
| "OBJECTIVES - While carbamazepine (CBZ) decreases thyroid hormone concentrations it rarely causes hypothyroidism." | 7.74 | Carbamazepine and risk of hypothyroidism: a prospective study. ( Horacek, J; Simko, J, 2007) |
| " This study aimed to evaluate thyroid function in men taking carbamazepine (CBZ), oxcarbazepine (OCBZ), or valproate (VPA) for epilepsy." | 7.71 | Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy. ( Isojärvi, JI; Kotila, M; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Turkka, J, 2001) |
| "We determined serum levels of triiodothyronine (T3), thyroxine (T4), free thyroxine (FT4), thyroxine-binding globulin (TBG), and thyroid-stimulating hormone (TSH) in 148 healthy children and 141 children with epilepsy who had been receiving CBZ (61 patients), VPA (51 patients), or PB (29 patients) for 12-161 months." | 7.70 | Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism. ( Castro-Gago, M; Del Río-Garma, M; Del Río-Garma, MC; Eirís-Puñal, J; Lojo-Rocamonde, S; Novo-Rodríguez, I, 1999) |
| "To assess the most efficient means of monitoring thyroid status in an epilepsy clinic, total thyroxine (T4), free thyroxine stimulating hormone (TSH) were measured in 71 adult patients treated long-term with either phenytoin (DPH), carbamazepine (CBZ) or sodium valproate (VAL)." | 7.67 | The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic. ( Borsey, DQ; Browning, MC; Connacher, AA; Davidson, DL; Jung, RT, 1987) |
| "Blood levels of phenytoin, total thyroxine, and free thyroxine were determined in 10 epileptic women during and following pregnancy." | 7.66 | Epilepsy and pregnancy. Serum thyroxine levels during phenytoin therapy. ( Ramsay, RE; Spellacy, WN; Strauss, RG; Wilder, BJ; Willmore, LJ, 1979) |
| " The aim of this study was to evaluate thyroid function in 78 girls taking carbamazepine (CBZ), oxcarbazepine (OXC), or valproate (VPA) monotherapy for epilepsy and after withdrawal of the treatment." | 5.11 | Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after withdrawal of medication. ( Isojärvi, JI; Knip, M; Mikkonen, K; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Vainionpää, LK, 2004) |
| "We studied serum calcium, phosphorus, alkaline phosphatase (ALP), thyroid hormones (total thyroxine [TT4], free thyroxine [FT4], thyroid-stimulating hormone [TSH]), parathyroid hormone (PH), and osteocalcine levels in children with epilepsy who had been receiving long-term carbamazepine (CBZ) therapy to determine whether there was any effect of CBZ therapy on these hormones." | 5.10 | Evaluation of thyroid and parathyroid functions in children receiving long-term carbamazepine therapy. ( Atas, B; Caksen, H; Cesur, Y; Dulger, H; Odabas, D; Tuncer, O, 2003) |
| " Therefore, we conducted a prospective longitudinal study to evaluate the effects of LEV and carbamazepine (CBZ) treatment on lipid profile and thyroid hormone levels in patients newly diagnosed with epilepsy." | 3.91 | Lipid and thyroid hormone levels in children with epilepsy treated with levetiracetam or carbamazepine: A prospective observational study. ( Iijima, K; Ishida, Y; Maruyama, A; Nagase, H; Nakagawa, T; Nishimura, N; Nishiyama, M; Nozu, K; Takami, Y; Tanaka, T; Tokumoto, S; Tomioka, K; Toyoshima, D; Yamaguchi, H, 2019) |
| " He had been administered phenytoin and gabapentin for the treatment of symptomatic traumatic epilepsy 8 years before." | 3.88 | Hypothyroidism induced by phenytoin and gabapentin: A Case Report. ( Ishii, K; Miyake, Z; Tamaoka, A, 2018) |
| "Female patients with epilepsy and an older age, AED polytherapy, and carbamazepine treatment had a higher risk of low fT4." | 3.85 | Effects of antiepileptic drugs on thyroid hormone function in epilepsy patients. ( Chuang, MJ; Chuang, YC; Fu, TY; Lu, YT; Shih, FY; Tsai, MH; Tsai, WC, 2017) |
| "The aim of this study was to evaluate the incidence of thyroid dysfunction during valproic acid (VPA) therapy in children and adolescents with epilepsy." | 3.78 | Subclinical hypothyroidism during valproic acid therapy in children and adolescents with epilepsy. ( Chae, JH; Chung, HR; Hwang, H; Hwang, YS; Kim, H; Kim, KJ; Kim, SH; Lim, BC, 2012) |
| "OBJECTIVES - While carbamazepine (CBZ) decreases thyroid hormone concentrations it rarely causes hypothyroidism." | 3.74 | Carbamazepine and risk of hypothyroidism: a prospective study. ( Horacek, J; Simko, J, 2007) |
| " This study aimed to evaluate thyroid function in men taking carbamazepine (CBZ), oxcarbazepine (OCBZ), or valproate (VPA) for epilepsy." | 3.71 | Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy. ( Isojärvi, JI; Kotila, M; Myllylä, VV; Pakarinen, AJ; Rättyä, J; Turkka, J, 2001) |
| "We determined serum levels of triiodothyronine (T3), thyroxine (T4), free thyroxine (FT4), thyroxine-binding globulin (TBG), and thyroid-stimulating hormone (TSH) in 148 healthy children and 141 children with epilepsy who had been receiving CBZ (61 patients), VPA (51 patients), or PB (29 patients) for 12-161 months." | 3.70 | Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism. ( Castro-Gago, M; Del Río-Garma, M; Del Río-Garma, MC; Eirís-Puñal, J; Lojo-Rocamonde, S; Novo-Rodríguez, I, 1999) |
| "We determined changes in serum concentrations of thyroid hormones during carbamazepine (CBZ) therapy during a 5-year prospective follow-up study of 20 patients with newly diagnosed epilepsy." | 3.69 | Thyroid and myocardial function after replacement of carbamazepine by oxcarbazepine. ( Airaksinen, KE; Isojärvi, JI; Mustonen, JN; Myllylä, VV; Pakarinen, AJ; Pelkonen, O; Rautio, A, 1995) |
| " There were no alterations in body weight or plasma levels of triiodotHyronine (T3) and thyroxine (T4)." | 3.69 | Long-term antiepileptic effects of chronic intake of CNK-602A, a thyrotropin-releasing hormone analogue, on spontaneously epileptic rats. ( Fujita, Y; Ishihara, K; Kimura, K; Momiyama, T; Sasa, M; Serikawa, T; Todo, N, 1996) |
| "Serum thyroid hormone and thyrotropin levels were assayed and the myocardial function was evaluated by measuring systolic time intervals both in 30 patients with epilepsy on long-term carbamazepine monotherapy and in 19 healthy volunteers." | 3.68 | Carbamazepine, serum thyroid hormones and myocardial function in epileptic patients. ( Airaksinen, KE; Isojärvi, JI; Myllylä, VV; Pakarinen, AJ; Repo, M; Salmela, P, 1993) |
| "To evaluate the effect of anticonvulsants on serum levels of free thyroxine (FT4) and thyroxine-binding globulin (TBG), 32 patients with epilepsy receiving long-term anticonvulsant treatment (mean duration 81." | 3.67 | Lowering effect of diphenylhydantoin on serum free thyroxine and thyroxine binding globulin (TBG). ( Hiraiwa, M; Miyasaka, M; Mori, K; Shimoda, S; Suzuki, H; Suzuki, Y; Yamazaki, N, 1984) |
| "The effects of carbamazepine monotherapy on thyroid function were evaluated in patients with epilepsy." | 3.67 | Thyroid function in epileptic patients treated with carbamazepine. ( Isojärvi, JI; Myllylä, VV; Pakarinen, AJ, 1989) |
| "To assess the most efficient means of monitoring thyroid status in an epilepsy clinic, total thyroxine (T4), free thyroxine stimulating hormone (TSH) were measured in 71 adult patients treated long-term with either phenytoin (DPH), carbamazepine (CBZ) or sodium valproate (VAL)." | 3.67 | The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic. ( Borsey, DQ; Browning, MC; Connacher, AA; Davidson, DL; Jung, RT, 1987) |
| "Blood levels of phenytoin, total thyroxine, and free thyroxine were determined in 10 epileptic women during and following pregnancy." | 3.66 | Epilepsy and pregnancy. Serum thyroxine levels during phenytoin therapy. ( Ramsay, RE; Spellacy, WN; Strauss, RG; Wilder, BJ; Willmore, LJ, 1979) |
| "Epilepsy is a chronic neurological disorder that is treated with multiple medications that can have significant side effects." | 1.72 | Thyroid functions as a parameter in monitoring of antiepileptic drugs. ( Acikgoz, M; Aciman Demirel, E; Atasoy, HT; Celebi, U; Comert, E; Piri Cinar, B, 2022) |
| "Carbamazepine-treated patients showed mean serum thyroid hormone levels significantly lower than baseline evaluation and the control group." | 1.42 | Evaluation of thyroid hormones in children receiving carbamazepine or valproate: a prospective study. ( Arapoglu, M; Dalgıç, N; Kafadar, İ; Kılıç, BA; Yalçın, K, 2015) |
| "Phenytoin levels were measured and found to be grossly elevated at 170 mmol/L." | 1.35 | Phenytoin toxicity and thyroid dysfunction. ( Betteridge, T; Fink, J, 2009) |
| " No correlation was found between duration or dosage of treatment and BMI-SDS, height-SDS, or androgen level." | 1.34 | Endocrine effects of valproate in adolescent girls with epilepsy. ( de Vries, L; Goldberg-Stern, H; Karasik, A; Kiviti, S; Landau, Z; Phillip, M, 2007) |
| "Bromide treatment was not associated with any significant change in these serum thyroid hormone concentrations." | 1.30 | Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants. ( Kantrowitz, LB; Melián, C; Nichols, R; Peterson, ME; Trepanier, LA, 1999) |
| "Phenobarbital is know to be a stimulator of the drug metabolizing enzyme system in the liver." | 1.26 | [The effect of primidone treatment of thyroid hormones in epileptic children and adolescents (author's transl)]. ( Fichsel, H; Knöpfle, G, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (45.00) | 18.7374 |
| 1990's | 10 (16.67) | 18.2507 |
| 2000's | 12 (20.00) | 29.6817 |
| 2010's | 9 (15.00) | 24.3611 |
| 2020's | 2 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Comert, E | 1 |
| Celebi, U | 1 |
| Piri Cinar, B | 1 |
| Acikgoz, M | 1 |
| Aciman Demirel, E | 1 |
| Atasoy, HT | 1 |
| Han, JY | 1 |
| Lee, IG | 1 |
| Shin, S | 1 |
| Park, J | 1 |
| Shih, FY | 1 |
| Chuang, YC | 1 |
| Chuang, MJ | 1 |
| Lu, YT | 1 |
| Tsai, WC | 1 |
| Fu, TY | 1 |
| Tsai, MH | 1 |
| Miyake, Z | 1 |
| Ishii, K | 1 |
| Tamaoka, A | 1 |
| Nishiyama, M | 1 |
| Takami, Y | 1 |
| Ishida, Y | 1 |
| Tomioka, K | 1 |
| Tanaka, T | 1 |
| Nagase, H | 1 |
| Nakagawa, T | 1 |
| Tokumoto, S | 1 |
| Yamaguchi, H | 1 |
| Toyoshima, D | 1 |
| Maruyama, A | 1 |
| Nozu, K | 1 |
| Nishimura, N | 1 |
| Iijima, K | 1 |
| Yılmaz, U | 1 |
| Yılmaz, TS | 1 |
| Akıncı, G | 1 |
| Korkmaz, HA | 1 |
| Tekgül, H | 1 |
| Kafadar, İ | 1 |
| Kılıç, BA | 1 |
| Arapoglu, M | 1 |
| Yalçın, K | 1 |
| Dalgıç, N | 1 |
| Zhang, YX | 1 |
| Shen, CH | 1 |
| Lai, QL | 1 |
| Fang, GL | 1 |
| Ming, WJ | 1 |
| Lu, RY | 1 |
| Ding, MP | 1 |
| Verrotti, A | 1 |
| Laus, M | 1 |
| Scardapane, A | 1 |
| Franzoni, E | 1 |
| Chiarelli, F | 1 |
| Betteridge, T | 1 |
| Fink, J | 1 |
| Aygün, F | 1 |
| Ekici, B | 1 |
| Aydinli, N | 1 |
| Aydin, BK | 1 |
| Baş, F | 1 |
| Tatli, B | 1 |
| Sahu, JK | 1 |
| Gulati, S | 1 |
| Kabra, M | 1 |
| Arya, R | 1 |
| Sharma, R | 1 |
| Gupta, N | 1 |
| Kaleekal, T | 1 |
| Reeta, Kh | 1 |
| Gupta, YK | 1 |
| Kim, SH | 2 |
| Chung, HR | 1 |
| Kim, H | 1 |
| Lim, BC | 1 |
| Chae, JH | 1 |
| Kim, KJ | 1 |
| Hwang, YS | 1 |
| Hwang, H | 1 |
| Arvio, M | 1 |
| Sipilä, I | 1 |
| Caksen, H | 1 |
| Dulger, H | 1 |
| Cesur, Y | 1 |
| Atas, B | 1 |
| Tuncer, O | 1 |
| Odabas, D | 1 |
| PAUSOUANT-FONTAINE, T | 1 |
| FLANDRE, C | 1 |
| MAUCHE, J | 1 |
| Vainionpää, LK | 1 |
| Mikkonen, K | 1 |
| Rättyä, J | 2 |
| Knip, M | 1 |
| Pakarinen, AJ | 5 |
| Myllylä, VV | 5 |
| Isojärvi, JI | 5 |
| Simko, J | 2 |
| Horácek, J | 2 |
| Waberzinek, G | 1 |
| de Vries, L | 1 |
| Karasik, A | 1 |
| Landau, Z | 1 |
| Phillip, M | 1 |
| Kiviti, S | 1 |
| Goldberg-Stern, H | 1 |
| Attilakos, A | 1 |
| Garoufi, A | 1 |
| Voudris, K | 1 |
| Mastroyianni, S | 1 |
| Fotinou, A | 1 |
| Papadimitriou, DT | 1 |
| Gavalakis, N | 1 |
| Prassouli, A | 1 |
| Katsarou, E | 1 |
| Suzuki, H | 1 |
| Yamazaki, N | 1 |
| Suzuki, Y | 1 |
| Hiraiwa, M | 1 |
| Shimoda, S | 1 |
| Mori, K | 1 |
| Miyasaka, M | 1 |
| Kaneko, S | 3 |
| Hirano, T | 1 |
| Fukushima, Y | 3 |
| Sato, T | 3 |
| Nomura, Y | 3 |
| Shinagawa, S | 3 |
| Ogawa, Y | 2 |
| Jabbari, B | 1 |
| Huott, AD | 1 |
| Strandjord, RE | 1 |
| Aanderud, S | 1 |
| Myking, OL | 1 |
| Johannessen, SI | 2 |
| Narita, S | 2 |
| Takebe, K | 1 |
| Arai, K | 1 |
| Ueda, S | 1 |
| Otani, K | 1 |
| Kurahashi, K | 1 |
| Tiihonen, M | 1 |
| Liewendahl, K | 1 |
| Waltimo, O | 1 |
| Ojala, M | 1 |
| Välimäki, M | 1 |
| Airaksinen, KE | 2 |
| Mustonen, JN | 1 |
| Rautio, A | 1 |
| Pelkonen, O | 1 |
| Zhu, SQ | 1 |
| Liu, XM | 1 |
| Ruan, XZ | 1 |
| Cai, Z | 1 |
| Repo, M | 1 |
| Salmela, P | 1 |
| Momiyama, T | 1 |
| Ishihara, K | 1 |
| Kimura, K | 1 |
| Todo, N | 1 |
| Fujita, Y | 1 |
| Serikawa, T | 1 |
| Sasa, M | 1 |
| Kantrowitz, LB | 1 |
| Peterson, ME | 1 |
| Trepanier, LA | 1 |
| Melián, C | 1 |
| Nichols, R | 1 |
| Gaskill, CL | 2 |
| Burton, SA | 2 |
| Gelens, HC | 2 |
| Ihle, SL | 2 |
| Miller, JB | 2 |
| Shaw, DH | 2 |
| Brimacombe, MB | 2 |
| Cribb, AE | 2 |
| Eirís-Puñal, J | 1 |
| Del Río-Garma, M | 1 |
| Del Río-Garma, MC | 1 |
| Lojo-Rocamonde, S | 1 |
| Novo-Rodríguez, I | 1 |
| Castro-Gago, M | 1 |
| Vrancken, AF | 1 |
| Braun, KP | 1 |
| de Valk, HW | 1 |
| Rinkel, GJ | 1 |
| Turkka, J | 1 |
| Kotila, M | 1 |
| Fichsel, H | 6 |
| Knöpfle, G | 6 |
| Rootwelt, K | 1 |
| Ganes, T | 1 |
| Strauss, RG | 1 |
| Ramsay, RE | 1 |
| Willmore, LJ | 1 |
| Spellacy, WN | 1 |
| Wilder, BJ | 1 |
| Saija, A | 1 |
| Princi, P | 1 |
| De Pasquale, R | 1 |
| Costa, G | 1 |
| De Sarro, GB | 1 |
| Jones, TH | 1 |
| Larkin, JG | 1 |
| Macphee, GJ | 1 |
| Beastall, GH | 2 |
| Brodie, MJ | 1 |
| Connacher, AA | 1 |
| Borsey, DQ | 1 |
| Browning, MC | 1 |
| Davidson, DL | 1 |
| Jung, RT | 1 |
| Kaciński, M | 1 |
| Sztefko, K | 1 |
| Szafran, Z | 1 |
| Stopyrowa, J | 1 |
| Kirichenko, VD | 1 |
| Cowan, RA | 1 |
| Gray, JM | 1 |
| Fogelman, I | 1 |
| Cathro, DM | 1 |
| Hardman, RP | 1 |
| Ilyés, I | 1 |
| Tornai, A | 1 |
| Kirilina, S | 1 |
| György, I | 1 |
| Kushnir, M | 1 |
| Weinstein, R | 1 |
| Landau, B | 1 |
| Shavit, G | 1 |
| Bechar, M | 1 |
| Gadoth, N | 1 |
| Christensen, LK | 1 |
| Bayley, TA | 1 |
| Higgins, HP | 1 |
| Row, VV | 1 |
| James, W | 1 |
| Vidal, R | 1 |
2 reviews available for thyroxine and Epilepsy
| Article | Year |
|---|---|
Effects of antiepileptic drug on thyroid hormones in patients with epilepsy: A meta-analysis.
Topics: Anticonvulsants; Databases, Bibliographic; Epilepsy; Female; Humans; Male; Thyroid Function Tests; T | 2016 |
[Epilepsy, disturbances of behavior and consciousness in presence of normal thyroxine levels: still, consider the thyroid gland].
Topics: Autoantibodies; Autoimmune Diseases of the Nervous System; Diagnosis, Differential; Epilepsy; Female | 2000 |
4 trials available for thyroxine and Epilepsy
| Article | Year |
|---|---|
Evaluation of thyroid and parathyroid functions in children receiving long-term carbamazepine therapy.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Child; Epilepsy; Humans; Matched-Pair | 2003 |
Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after withdrawal of medication.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cross-Sectional Studies; Drug Administration Sche | 2004 |
Thyroid status of patients receiving long-term anticonvulsant therapy assessed by peripheral parameters: a placebo-controlled thyroxine therapy trial.
Topics: Adult; Age Distribution; Anticonvulsants; Carbamazepine; Comorbidity; Cross-Over Studies; Double-Bli | 1995 |
[Clinical pharmacology (13): therapy control. Discussion introduction].
Topics: Clinical Trials as Topic; Drug Therapy; Epilepsy; Humans; Phenytoin; Thyroxine | 1970 |
54 other studies available for thyroxine and Epilepsy
| Article | Year |
|---|---|
Thyroid functions as a parameter in monitoring of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Epilepsy; Humans; Retrospective Studies; Thyroid Gland; Thyrotropin; Thyroxi | 2022 |
Seizure duration may increase thyroid-stimulating hormone levels in children experiencing a seizure.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Cortical Excitability; Epilepsy; Female; Follo | 2020 |
Effects of antiepileptic drugs on thyroid hormone function in epilepsy patients.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Drug Therapy, Combinati | 2017 |
Hypothyroidism induced by phenytoin and gabapentin: A Case Report.
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric | 2018 |
Lipid and thyroid hormone levels in children with epilepsy treated with levetiracetam or carbamazepine: A prospective observational study.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol, HDL; Cholesterol, | 2019 |
The effect of antiepileptic drugs on thyroid function in children.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Hypothyroidism; Infa | 2014 |
Evaluation of thyroid hormones in children receiving carbamazepine or valproate: a prospective study.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Prospective Studi | 2015 |
Thyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate.
Topics: Anticonvulsants; Carbamazepine; Child; Drug Administration Schedule; Epilepsy; Female; Humans; Linea | 2009 |
Phenytoin toxicity and thyroid dysfunction.
Topics: Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Humans; Hypothyroidism; Middle Aged; Phenytoin | 2009 |
Thyroid hormones in children on antiepileptic therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Foll | 2012 |
Evaluation of subclinical hypothyroidism in ambulatory children with controlled epilepsy on valproate monotherapy.
Topics: Adolescent; Ambulatory Care; Antibodies; Anticonvulsants; Case-Control Studies; Child; Child, Presch | 2012 |
Subclinical hypothyroidism during valproic acid therapy in children and adolescents with epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Hypothyroidism; Severity of | 2012 |
[Psychomotor slowness of a mentally retarded woman].
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexan | 2001 |
[Endocrine factors in the epileptogenic aptitude of the cerebral cortex of albino rats; influence of thyroxin].
Topics: Animals; Aptitude; Cerebral Cortex; Epilepsy; Nervous System Physiological Phenomena; Rats; Thyroxin | 1953 |
Severe hypothyroidism as a complication of anticonvulsant treatment.
Topics: Aged; Anticonvulsants; Epilepsy; Female; Humans; Hypothyroidism; Severity of Illness Index; Thyrotro | 2004 |
Endocrine effects of valproate in adolescent girls with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Body Height; Body Mass Index; Child; Comorbidity; Epilepsy; Fema | 2007 |
Thyroid dysfunction associated with increased low-density lipoprotein cholesterol in epileptic children treated with carbamazepine monotherapy: a causal relationship?
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol, LDL; Epilepsy; Fem | 2007 |
Carbamazepine and risk of hypothyroidism: a prospective study.
Topics: Adult; Anticonvulsants; Carbamazepine; Diabetic Neuropathies; Down-Regulation; Epilepsy; Humans; Hyp | 2007 |
Lowering effect of diphenylhydantoin on serum free thyroxine and thyroxine binding globulin (TBG).
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Phenytoin; | 1984 |
Foetal head growth retardation due to antiepileptic drugs: with reference to GH, TSH, T4, T3 and reverse T3 concentrations.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Growth Retardation; Growth Hormone; Humans; Infant, | 1983 |
Seizures in thyrotoxicosis.
Topics: Adult; Aged; Epilepsies, Partial; Epilepsy; Female; Humans; Hyperthyroidism; Male; Middle Aged; Thyr | 1980 |
Influence of carbamazepine on serum thyroxine and triiodothyronine in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Thyroid | 1981 |
[Fetal head growth retardation due to maternal antiepileptic drug use--with reference to GH, TSH, T4, T3 and R-T3].
Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Growth Retardation; Growth Hormone; Humans; Pregnanc | 1982 |
Effects of antiepileptic drugs on hGH, TSH, and thyroid hormone concentrations during pregnancy.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Blood; Growth Hormone; Humans; Infant, Newborn; Preg | 1982 |
Thyroid and myocardial function after replacement of carbamazepine by oxcarbazepine.
Topics: Adolescent; Adult; Anticonvulsants; Antipyrine; Carbamazepine; Cytochrome P-450 Enzyme System; Echoc | 1995 |
Changes of thyroid hormone levels in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Thyrotropin; Thyro | 1994 |
Carbamazepine, serum thyroid hormones and myocardial function in epileptic patients.
Topics: Adult; Carbamazepine; Epilepsy; Female; Heart; Humans; Male; Systole; Thyroxine; Triiodothyronine | 1993 |
Long-term antiepileptic effects of chronic intake of CNK-602A, a thyrotropin-releasing hormone analogue, on spontaneously epileptic rats.
Topics: Administration, Oral; Animals; Behavior, Animal; Body Weight; Disease Models, Animal; Eating; Epilep | 1996 |
Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants.
Topics: Animals; Anticonvulsants; Bromides; Dog Diseases; Dogs; Drug Therapy, Combination; Epilepsy; Female; | 1999 |
Effects of phenobarbital treatment on serum thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anticonvulsants; Aspartate Aminotransferases; B | 1999 |
Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Hypothyro | 1999 |
Changes in serum thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs receiving phenobarbital for one year.
Topics: Analysis of Variance; Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Female; Male; Phenobar | 2000 |
Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; gamma-Glutamyltransfe | 2001 |
[Carbamacepine induced changes of thyroid hormones in epileptic children and juveniles (author's transl)].
Topics: Carbamazepine; Child; Cholesterol; Epilepsy; Female; Humans; Long-Term Care; Male; Thyroid Function | 1977 |
Effects of anticonvulsant drugs on thyroid hormones in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Dr | 1978 |
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones | 1978 |
[Changes in the thyroid hormone system with combined anticonvulsion treatment of epileptic children and adolescents (author's transl)].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Drug Therapy, Combination; Enzyme In | 1977 |
[The effect of primidone treatment of thyroid hormones in epileptic children and adolescents (author's transl)].
Topics: Adolescent; Child; Enzyme Induction; Epilepsy; Female; Humans; Iodine; Liver; Male; Phenobarbital; P | 1977 |
Epilepsy and pregnancy. Serum thyroxine levels during phenytoin therapy.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Epilepsy; Female; Fetus; Humans; Infant, Newborn; | 1979 |
[The influence on the thyroid hormone system by long-term anticonvulsive therapy with valproat (author's transl)].
Topics: Acetates; Adolescent; Child; Cholesterol; Epilepsy; Humans; Iodine; Protein Binding; Thyroid Gland; | 1976 |
[Influencing of the thyroid hormone system by long-term treatment with 5-5 diphenylhydantion in children and adolescens (author's transl)].
Topics: Adolescent; Child; Epilepsy; Female; Humans; Hypothalamus; Iodine; Liver; Male; Phenytoin; Protein B | 1976 |
Evaluation of local cerebral glucose utilization and the permeability of the blood-brain barrier in the genetically epilepsy-prone rat.
Topics: Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cerebrovascular Ci | 1992 |
Sodium valproate-induced menstrual disturbance in young women.
Topics: Adolescent; Amenorrhea; Epilepsy; Female; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormon | 1991 |
Thyroid hormone concentrations in epileptic patients.
Topics: Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Humans; Phenytoin; Thyrotropin; Thyroxi | 1989 |
Thyroid function in epileptic patients treated with carbamazepine.
Topics: Adolescent; Adult; Aged; Carbamazepine; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Ag | 1989 |
The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Midd | 1987 |
[Serum levels of triiodothyronine, thyroxine and thyrotropin in children with epilepsy treated with amizepine, luminal and mizodine in a monotherapy system. Preliminary report].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbit | 1988 |
[Basal levels of thyroxine, somatotropin and cortisol in children with epilepsy].
Topics: Adolescent; Child; Child, Preschool; Epilepsy; Female; Growth Hormone; Humans; Hydrocortisone; Male; | 1986 |
Hormone binding globulins and anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Carrier Proteins; Epilepsy; Female; Humans; Male; Middle Aged; Sex Factors; | 1985 |
Sub-normal serum thyroxine levels associated with carbamazepine and valproic acid treatment.
Topics: Carbamazepine; Child; Diabetes Complications; Drug Therapy, Combination; Epilepsy; Humans; Male; Thy | 1985 |
Influence of anticonvulsant drugs on thyroid hormones in epileptic children.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Mephenytoin; Phenytoin; Primidone; Thyro | 1985 |
Hypothyroidism and phenytoin intoxication.
Topics: Aged; Epilepsy; Female; Humans; Hypothyroidism; Phenytoin; Thyrotropin; Thyroxine | 1985 |
A case of anorexia.
Topics: Acetone; Adult; Amenorrhea; Anorexia Nervosa; Autopsy; Blood Pressure; Body Weight; Diet, Reducing; | 1973 |
The metabolic significance of thyroxine-binding globulin. Studies in a family with decreased thyroxine-binding globulin.
Topics: Adolescent; Adult; Aged; Basal Metabolism; Blood Protein Disorders; Child; Epilepsy; Female; Humans; | 1969 |