amifampridine has been researched along with Epilepsy in 2 studies
Amifampridine: 4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wirtz, PW | 1 |
| Titulaer, MJ | 1 |
| Gerven, JM | 1 |
| Verschuuren, JJ | 1 |
| Albowitz, B | 1 |
| Kuhnt, U | 1 |
| Ehrenreich, L | 1 |
1 review available for amifampridine and Epilepsy
| Article | Year |
|---|---|
3,4-diaminopyridine for the treatment of Lambert-Eaton myasthenic syndrome.
Topics: 4-Aminopyridine; Action Potentials; Amifampridine; Calcium Channels; Cholinergic Agents; Clinical Pr | 2010 |
1 other study available for amifampridine and Epilepsy
| Article | Year |
|---|---|
Optical recording of epileptiform voltage changes in the neocortical slice.
Topics: 4-Aminopyridine; Amifampridine; Animals; Bicuculline; Cerebral Cortex; Convulsants; Electrophysiolog | 1990 |