oxotremorine has been researched along with Epilepsy in 4 studies
Oxotremorine: A non-hydrolyzed muscarinic agonist used as a research tool.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sigmoid dose-response curves were plotted, and the IC50s were calculated." | 1.30 | Comparison of the effects of M1 and M2 muscarinic receptor activation in the absence of GABAergic inhibition in immature rat hippocampal CA3 area. ( Beaucher, J; Harnois, C; Psarropoulou, C, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Whalley, BJ | 2 |
| Postlethwaite, M | 2 |
| Constanti, A | 3 |
| Psarropoulou, C | 1 |
| Beaucher, J | 1 |
| Harnois, C | 1 |
| Libri, V | 1 |
| Bowery, NG | 1 |
4 other studies available for oxotremorine and Epilepsy
| Article | Year |
|---|---|
Further characterization of muscarinic agonist-induced epileptiform bursting activity in immature rat piriform cortex, in vitro.
Topics: Animals; Brain; Cell Membrane; Epilepsy; Female; In Vitro Techniques; Male; Muscarinic Agonists; Neu | 2005 |
Developmental changes in presynaptic muscarinic modulation of excitatory and inhibitory neurotransmission in rat piriform cortex in vitro: relevance to epileptiform bursting susceptibility.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Causality; Epilepsy; Excitatory Postsynaptic Po | 2006 |
Comparison of the effects of M1 and M2 muscarinic receptor activation in the absence of GABAergic inhibition in immature rat hippocampal CA3 area.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bicuculline; Carbacho | 1998 |
Blockade of GABA(B) receptors facilitates muscarinic agonist-induced epileptiform activity in immature rat piriform cortex in vitro.
Topics: Animals; Benzylamines; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Electric Sti | 1998 |