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nicardipine and Epilepsy

nicardipine has been researched along with Epilepsy in 6 studies

Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"Dizocilpine inhibits the seizure of the amygdala kindling and improve the antiepileptic activity of phenobarbital, valproate and nicardipine, indicating that these combination may provide a new approach for treating epilepsy."3.72Effect of combination of dizocilpine with general antiepileptic drugs on amygdala kindling models in rats. ( Gao, GM; Yang, ZH; Yue, W; Zhao, YJ; Zhong, WZ, 2004)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhong, WZ2
Zhao, YJ1
Gao, GM1
Yang, ZH1
Yue, W2
Momiyama, T1
Ishihara, K1
Serikawa, T1
Moritake, K1
Sasa, M1
Moltó-Jordà, JM1
Matías-Guiu, J1
Wang, L1
Zhang, F1
Liu, ZT1
Pascual-Castroviejo, I1
Deonna, T1
Roulet, E1

Reviews

1 review available for nicardipine and Epilepsy

ArticleYear
[Nicardipine and its indications in neurology].
    Revista de neurologia, 1997, Volume: 25, Issue:144

    Topics: Brain Ischemia; Calcium Channel Blockers; Dementia; Epilepsy; Humans; Migraine Disorders; Moyamoya D

1997

Other Studies

5 other studies available for nicardipine and Epilepsy

ArticleYear
Effect of combination of dizocilpine with general antiepileptic drugs on amygdala kindling models in rats.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:2

    Topics: Amygdala; Animals; Anticonvulsants; Dizocilpine Maleate; Electric Stimulation; Epilepsy; Female; Kin

2004
Effect of nicardipine on abnormal excitability of CA3 pyramidal cells in hippocampal slices of spontaneously epileptic rats.
    European journal of pharmacology, 1995, Jul-04, Volume: 280, Issue:2

    Topics: Animals; Calcium; Calcium Channel Blockers; Endoplasmic Reticulum, Smooth; Epilepsy; Hippocampus; Me

1995
Inhibition of nicardipine on amygdala kindling in rats.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:4

    Topics: Amygdala; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Electric Stimulation; Epilepsy;

2001
Nicardipine in the treatment of acquired aphasia and epilepsy.
    Developmental medicine and child neurology, 1990, Volume: 32, Issue:10

    Topics: Aphasia; Arteritis; Cerebral Arterial Diseases; Child; Epilepsy; Humans; Nicardipine; Syndrome

1990
Treatment of acquired aphasia and epilepsy.
    Developmental medicine and child neurology, 1991, Volume: 33, Issue:9

    Topics: Aphasia; Arteritis; Child; Electroencephalography; Epilepsy; Evoked Potentials; Humans; Nicardipine

1991