bupivacaine has been researched along with Epilepsy in 3 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serial arterial plasma levobupivacaine concentrations following scalp blockade were measured to 2 h in 10 patients booked for awake craniotomy for epilepsy or tumour surgery." | 3.73 | Plasma levobupivacaine concentrations following scalp block in patients undergoing awake craniotomy. ( Cormack, JR; Costello, TG; Harris, K; LaFerlita, B; Mather, LE; Murphy, MA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sites, BD | 1 |
| Blike, G | 1 |
| Cravero, J | 1 |
| Andeweg, S | 1 |
| Beach, M | 1 |
| Costello, TG | 1 |
| Cormack, JR | 1 |
| Mather, LE | 1 |
| LaFerlita, B | 1 |
| Murphy, MA | 1 |
| Harris, K | 1 |
| Stoneham, MD | 1 |
| Bree, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Scalp Block With Bupivacaine Versus Levobupivacaine on Haemodynamic Response to Head Pinning and Efficacy on Postoperative Analgesia[NCT02497040] | Phase 4 | 90 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02497040)
Timeframe: 220+-70 minutes
| Intervention | mmHg (Mean) |
|---|---|
| Bupivacaine,Levobupivacaine | 110 |
| Levobupivacaine | 105 |
| Bupivacaine | 100 |
3 other studies available for bupivacaine and Epilepsy
| Article | Year |
|---|---|
Single-dose caudal anaesthesia for two infants undergoing diagnostic brain magnetic resonance imaging: high risk and nonhigh risk.
Topics: Anesthesia, Caudal; Anesthetics, Local; Apnea; Brain; Bupivacaine; Craniofacial Abnormalities; Epile | 2003 |
Plasma levobupivacaine concentrations following scalp block in patients undergoing awake craniotomy.
Topics: Adult; Anesthetics, Local; Brain Neoplasms; Bupivacaine; Craniotomy; Epilepsy; Female; Humans; Levob | 2005 |
Epileptic seizure during awake carotid endarterectomy.
Topics: Aged; Anesthetics, Local; Bupivacaine; Carotid Artery, Internal; Carotid Stenosis; Cervical Plexus; | 1999 |