cyclothiazide has been researched along with Epilepsy in 5 studies
cyclothiazide: inhibits the desensitization of AMPA-type receptors; structure
cyclothiazide : 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 2 (40.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Sun, Y | 2 |
Wu, Z | 1 |
Kong, S | 3 |
Jiang, D | 1 |
Pitre, A | 1 |
Wang, Y | 3 |
Chen, G | 3 |
Qi, JS | 1 |
Fan, J | 1 |
Jiang, M | 1 |
Qian, B | 1 |
Liu, J | 1 |
Fan, M | 1 |
Seifert, G | 1 |
Hüttmann, K | 1 |
Schramm, J | 1 |
Steinhäuser, C | 1 |
Addae, JI | 1 |
Ali, N | 1 |
Youssef, FF | 1 |
Stone, TW | 1 |
5 other studies available for cyclothiazide and Epilepsy
Article | Year |
---|---|
Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABAA receptors.
Topics: Animals; Benzothiadiazines; Cells, Cultured; Epilepsy; Female; gamma-Aminobutyric Acid; HEK293 Cells | 2013 |
BDNF-TrkB signaling pathway mediates the induction of epileptiform activity induced by a convulsant drug cyclothiazide.
Topics: Action Potentials; Analysis of Variance; Animals; Antibodies; Antihypertensive Agents; Benzothiadiaz | 2009 |
Cyclothiazide induces seizure behavior in freely moving rats.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Benzothiadiazines; Brain; Convulsants; Disease M | 2010 |
Enhanced relative expression of glutamate receptor 1 flip AMPA receptor subunits in hippocampal astrocytes of epilepsy patients with Ammon's horn sclerosis.
Topics: Alternative Splicing; Astrocytes; Benzothiadiazines; Cell Separation; Epilepsy; Hippocampus; Humans; | 2004 |
AMPA receptor activation reduces epileptiform activity in the rat neocortex.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anim | 2007 |