Page last updated: 2024-10-26

dipyridamole and Epilepsy

dipyridamole has been researched along with Epilepsy in 3 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"Epilepsy is characterized by the manifestation of spontaneous and recurrent seizures."1.91The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish. ( Bertoncello, KT; Bonan, CD, 2023)
" Analysis of dose-response curves yielded the following IC50 values: adenosine, 1."1.27Adenosine inhibits epileptiform activity arising in hippocampal area CA3. ( Ault, B; Wang, CM, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Bertoncello, KT1
Bonan, CD1
Nosengo, N1
Ault, B1
Wang, CM1

Other Studies

3 other studies available for dipyridamole and Epilepsy

ArticleYear
The Effect of Adenosine Signaling on Memory Impairment Induced by Pentylenetetrazole in Zebrafish.
    Neurochemical research, 2023, Volume: 48, Issue:6

    Topics: Adenosine; Animals; Dipyridamole; Epilepsy; Pentylenetetrazole; Quality of Life; Seizures; Valproic

2023
Can you teach old drugs new tricks?
    Nature, 2016, 06-16, Volume: 534, Issue:7607

    Topics: Animals; Azoles; Bipolar Disorder; Carbazoles; Clinical Trials, Phase II as Topic; Dipyridamole; Dru

2016
Adenosine inhibits epileptiform activity arising in hippocampal area CA3.
    British journal of pharmacology, 1986, Volume: 87, Issue:4

    Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Enzyme Induction; Epilepsy; Evoked Potentials

1986