Page last updated: 2024-10-21

ibotenic acid and Epilepsy

ibotenic acid has been researched along with Epilepsy in 13 studies

Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's7 (53.85)18.2507
2000's3 (23.08)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takano, T1
Rangon, CM1
Fortes, S1
Lelièvre, V1
Leroux, P1
Plaisant, F1
Joubert, C1
Lanfumey, L1
Cohen-Salmon, C1
Gressens, P1
Yoneda, Y1
Ferland, RJ1
Applegate, CD1
Hagemann, G1
Redecker, C1
Witte, OW1
Eid, T1
Du, F1
Schwarcz, R1
Gale, K1
Zhong, P1
Miller, LP1
Murray, TF1
Sidorov, BM1
B'ianki, R1
Francheskoni, V1
Berton, F1
Hosford, DA1
Crain, BJ1
Cao, Z1
Bonhaus, DW1
Friedman, AH1
Okazaki, MM1
Nadler, JV1
McNamara, JO1
Innocenti, GM1
Berbel, P1
Pedder, SC1
Wilcox, RI1
Tuchek, JM1
Johnson, DD1
Crawford, RD1
Turski, L1
Meldrum, BS1
Cavalheiro, EA1
Calderazzo-Filho, LS1
Bortolotto, ZA1
Ikonomidou-Turski, C1
Turski, WA1
Jellestad, FK1
Grahnstedt, S1

Reviews

1 review available for ibotenic acid and Epilepsy

ArticleYear
[Receptive mechanisms of excitatory amino acid signals].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1993, Volume: 113, Issue:7

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ischemia; Ep

1993

Other Studies

12 other studies available for ibotenic acid and Epilepsy

ArticleYear
Altered distribution of inhibitory interneurons in polymicrogyria.
    Epilepsy research, 2012, Volume: 102, Issue:1-2

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Corpus Callosum; Cricetinae; Disease Models, Animal; Epi

2012
Chronic mild stress during gestation worsens neonatal brain lesions in mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jul-11, Volume: 27, Issue:28

    Topics: Animals; Animals, Newborn; Brain; Brain Diseases; Chronic Disease; Corticosterone; Epilepsy; Female;

2007
The role of the ventromedial nucleus of the hypothalamus in epileptogenesis.
    Neuroreport, 1998, Nov-16, Volume: 9, Issue:16

    Topics: Animals; Behavior, Animal; Brain Stem; Convulsants; Denervation; Epilepsy; Excitatory Amino Acid Ago

1998
Intact functional inhibition in the surround of experimentally induced focal cortical dysplasias in rats.
    Journal of neurophysiology, 2000, Volume: 84, Issue:1

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Electrophysiology; Epilepsy; Exc

2000
Ibotenate injections into the pre- and parasubiculum provide partial protection against kainate-induced epileptic damage in layer III of rat entorhinal cortex.
    Epilepsia, 2001, Volume: 42, Issue:7

    Topics: Animals; Convulsants; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Epilepsy, Temporal Lobe;

2001
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
    Epilepsy research. Supplement, 1992, Volume: 8

    Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Am

1992
[Epileptiform activity in the rat hippocampal slices isolated after local lesion of the septum by ibotenic acid].
    Neirofiziologiia = Neurophysiology, 1991, Volume: 23, Issue:5

    Topics: Action Potentials; Animals; Epilepsy; Evoked Potentials; Hippocampus; Ibotenic Acid; In Vitro Techni

1991
Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:2

    Topics: Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Binding Sites; Cell Sur

1991
Analysis of an experimental cortical network: I). Architectonics of visual areas 17 and 18 after neonatal injections of ibotenic acid; similarities with human microgyria.
    Journal of neural transplantation & plasticity, 1991, Volume: 2, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Atropine; Brain; Cats; Epilepsy; Female; Humans; Ibotenic Acid; Mi

1991
Quisqualate receptors in epileptic fowl: the absence of coupling between quisqualate and N-methyl-D-aspartate receptors.
    European journal of pharmacology, 1990, Jan-03, Volume: 175, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Brain; Chickens;

1990
Paradoxical anticonvulsant activity of the excitatory amino acid N-methyl-D-aspartate in the rat caudate-putamen.
    Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:6

    Topics: Animals; Anticonvulsants; Aspartic Acid; Caudate Nucleus; Epilepsy; Ibotenic Acid; Male; N-Methylasp

1987
Electroencephalographic activity after kainic and ibotenic acid injections in the amygdaloid complex of rats.
    Brain research, 1985, Aug-12, Volume: 340, Issue:2

    Topics: Amygdala; Animals; Behavior, Animal; Electroencephalography; Epilepsy; Ibotenic Acid; Injections, In

1985