Page last updated: 2024-10-17

coumarin and Epilepsy

coumarin has been researched along with Epilepsy in 2 studies

2H-chromen-2-one: coumarin derivative

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"Antiepileptic drugs are the mainstream treatment for epilepsy; however, the drug resistance occurring in 20-30% of patients and side effects of available medications have resulted in a search for natural remedies that can support disease therapy."6.61Coumarins as potential supportive medication for the treatment of epilepsy. ( Andres-Mach, M; Bryda, J; Szewczyk, A; Zagaja, M, 2019)
"Antiepileptic drugs are the mainstream treatment for epilepsy; however, the drug resistance occurring in 20-30% of patients and side effects of available medications have resulted in a search for natural remedies that can support disease therapy."2.61Coumarins as potential supportive medication for the treatment of epilepsy. ( Andres-Mach, M; Bryda, J; Szewczyk, A; Zagaja, M, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bryda, J1
Zagaja, M1
Szewczyk, A1
Andres-Mach, M1
Sotaniemi, EA1
Rautio, A1
Bäckstrom, M1
Arvela, P1
Pelkonen, O1

Reviews

1 review available for coumarin and Epilepsy

ArticleYear
Coumarins as potential supportive medication for the treatment of epilepsy.
    Acta neurobiologiae experimentalis, 2019, Volume: 79, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Coumarins; Disease Models, Animal; Epilepsy; Humans; Seizures

2019

Other Studies

1 other study available for coumarin and Epilepsy

ArticleYear
CYP3A4 and CYP2A6 activities marked by the metabolism of lignocaine and coumarin in patients with liver and kidney diseases and epileptic patients.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Capsules; Coumarins; Cytochrome P-

1995