doxepin has been researched along with Epilepsy in 2 studies
Doxepin: A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
doxepin : A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an antidepressant drug.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| " He was prescribed doxepin for insomnia and four antiepileptics for seizures." | 8.31 | Chronic Doxepin Toxicity Masquerading as Epilepsy in a 10-Year-Old Boy. ( Burns, MM; Watson, CJ; Whitledge, JD, 2023) |
| " He was prescribed doxepin for insomnia and four antiepileptics for seizures." | 4.31 | Chronic Doxepin Toxicity Masquerading as Epilepsy in a 10-Year-Old Boy. ( Burns, MM; Watson, CJ; Whitledge, JD, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Whitledge, JD | 1 |
| Watson, CJ | 1 |
| Burns, MM | 1 |
| Ojemann, LM | 1 |
| Friel, PN | 1 |
| Trejo, WJ | 1 |
| Dudley, DL | 1 |
2 other studies available for doxepin and Epilepsy
| Article | Year |
|---|---|
Chronic Doxepin Toxicity Masquerading as Epilepsy in a 10-Year-Old Boy.
Topics: Ataxia; Child; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Doxepin; Epilepsy; Humans; Male; S | 2023 |
Effect of doxepin on seizure frequency in depressed epileptic patients.
Topics: Adolescent; Adult; Depression; Doxepin; Epilepsy; Female; Humans; Male; Middle Aged | 1983 |