Page last updated: 2024-10-21

phaclofen and Epilepsy

phaclofen has been researched along with Epilepsy in 3 studies

phaclofen: peripheral & central baclofen & GABA antagonist; structure given in first source

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Segal, MM1
Furshpan, EJ1
Karlsson, G1
Olpe, HR1
Chamberlin, NL1
Dingledine, R1

Other Studies

3 other studies available for phaclofen and Epilepsy

ArticleYear
Epileptiform activity in microcultures containing small numbers of hippocampal neurons.
    Journal of neurophysiology, 1990, Volume: 64, Issue:5

    Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Cells, Cultured; Epilepsy; Evoked Potentials; Hipp

1990
Inhibitory processes in normal and epileptic-like rat hippocampal slices: the role of GABAB receptors.
    European journal of pharmacology, 1989, Apr-25, Volume: 163, Issue:2-3

    Topics: Animals; Baclofen; Bicuculline; Epilepsy; Hippocampus; In Vitro Techniques; Male; Penicillins; Rats;

1989
Control of epileptiform burst rate by CA3 hippocampal cell afterhyperpolarizations in vitro.
    Brain research, 1989, Jul-17, Volume: 492, Issue:1-2

    Topics: Action Potentials; Animals; Baclofen; Epilepsy; Hippocampus; In Vitro Techniques; Membrane Potential

1989
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