Page last updated: 2024-10-31

apnea and Epilepsy

apnea has been researched along with Epilepsy in 88 studies

Apnea: A transient absence of spontaneous respiration.

Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

Research Excerpts

ExcerptRelevanceReference
"Methylxanthine therapy is commonly used for apnea of prematurity but in the absence of adequate data on its efficacy and safety."9.12Long-term effects of caffeine therapy for apnea of prematurity. ( Barrington, KJ; Davis, P; Doyle, LW; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W, 2007)
"Episodic apnea leading to asphyxia is a relatively common disorder of young children."8.77Sleep apnea in infancy and childhood. ( Thach, BT, 1985)
" The aim of this study was to evaluate the incidence of ictal apnea (IA) and related hypoxemia during seizures."8.12Ictal apnea: A prospective monocentric study in patients with epilepsy. ( Ballerini, A; Cioclu, MC; Giovannini, G; Giunta, L; Meletti, S; Micalizzi, E; Talami, F; Turchi, G; Vaudano, AE, 2022)
"The primary cause of seizure-induced death for all mice was apnea, as (1) apnea began during a seizure and continued for tens of minutes until terminal asystole, and (2) death was prevented by mechanical ventilation."8.02Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ( Blizzard, EA; Goodkin, HP; Meisler, MH; Panchal, PS; Patel, MK; Richerson, GB; Saraf, P; Teran, FA; Wagley, PK; Wagnon, JL; Wengert, ER; Wenker, IC, 2021)
"This case series aimed to characterize the clinical features, management, and outcomes of apnea in infants with trisomy 18."7.96Management of apnea in infants with trisomy 18. ( Fujiyoshi, J; Ichimiya, Y; Inoue, H; Ochiai, M; Ohga, S; Sakai, Y; Sanefuji, M; Sawano, T; Taira, R; Torio, M, 2020)
" However, the mechanisms underlying seizure-induced central apnea in pediatric epilepsy are unknown."7.96A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy. ( Ciliberto, MA; Dlouhy, BJ; Harmata, GI; Howard, MA; Kovach, CK; Rhone, AE; Richerson, GB; Steinschneider, M; Sullivan, AW; Tranel, D; Wemmie, JA, 2020)
"To determine the relationship between serum serotonin (5-HT) levels, ictal central apnea (ICA), and postconvulsive central apnea (PCCA) in epileptic seizures."7.91Postictal serotonin levels are associated with peri-ictal apnea. ( Bateman, LM; Devinsky, O; Diehl, B; Faingold, CL; Friedman, D; Hampson, JP; Harper, RM; Lacuey, N; Lhatoo, SD; Murugesan, A; Nei, M; Rani, MRS; Richerson, G; Sainju, RK; Schuele, S; Vilella, L, 2019)
"We report an 11-month-old boy with acetazolamide-responsive epileptic apnea and inherited glycosylphosphatidylinositol (GPI)-anchor deficiency who presented with decreased serum alkaline phosphatase associated with compound PIGT mutations."7.88Epileptic apnea in a patient with inherited glycosylphosphatidylinositol anchor deficiency and PIGT mutations. ( Adachi, Y; Ishiyama, A; Kinoshita, T; Kohashi, K; Matsumoto, N; Miya, K; Murakami, Y; Ohba, C; Saitsu, H; Sasaki, M; Sato, N; Sugai, K; Tanaka, T; Yuasa, S, 2018)
"We report the case of a child prospectively followed in our institution for a severe, neonatal onset epilepsy presenting with severe attacks of apnea that were not initially recognized as seizure since they were not associated with any abnormal movement and since interictal EEG was normal."7.85Heterogeneity of FHF1 related phenotype: Novel case with early onset severe attacks of apnea, partial mitochondrial respiratory chain complex II deficiency, neonatal onset seizures without neurodegeneration. ( Abidi, A; Cacciagli, P; Chabrol, B; Mignon-Ravix, C; Milh, M; Villard, L; Villeneuve, N, 2017)
"Many children with trisomy 18 have apneas from the neonatal period."7.81Apneas observed in trisomy 18 neonates should be differentiated from epileptic apneas. ( Asada, H; Fukasawa, T; Hattori, T; Kato, Y; Kubota, T; Matsusawa, K; Negoro, T; Tanaka, M, 2015)
"A 16-day-old infant developed several mild episodes of apnea that culminated in a severe cyanotic episode requiring resuscitation."7.75Severe apnea in an infant exposed to lamotrigine in breast milk. ( Aronsen, L; Nordmo, E; Småbrekke, L; Vorren, S; Wasland, K, 2009)
"Apnea as an isolated manifestation of seizures is well described in neonates but is only occasionally observed in infants."7.74Apnea caused by mesial temporal lobe mass lesions in infants: report of 3 cases. ( Avellino, AM; Ellenbogen, RG; Kuratani, J; Miyagawa, T; Ojemann, JG; Saneto, RP; Sotero, M, 2007)
"Two months-old girl with psychomotor retardation had aminophylline-resistant apnea attacks and was investigated by video-EEG recording."7.72[A case of infantile epileptic apnea with congenital brain anomaly]. ( Hamano, K; Iwasaki, N; Matsui, A; Ohto, T; Takahashi, M; Tanaka, R, 2003)
" In three cases where no cause was found the EA was not repeated, although apnea monitorization was necessary for several months because of the anxiety of the family."7.69[Clinical significance of episodes of apnea in babies]. ( Arcas, J; Barrio, MI; Leal, J; López-Martín, V; Martínez-Bermejo, A; Pascual-Castroviejo, I; Roche, C, 1997)
"The authors report the observation of an infant who begins at the age of 7 months to present episodes of epileptic apnea with cyanosis, lost of consciousness, hypotony and sometimes ocular revulsion and distal myoclonia."7.67[Episodes of apnea in an infant: unusual forms of epileptic seizures]. ( Campistol, J; Estivill, E; Fernandez-Alvarez, E; Roger, J; Sanmarti, FX, 1985)
"A 33 year old male, suffering from Kleine-Levine syndrome associated with periods of apnea during the hypersomnic attacks, is reported."7.66Kleine-Levin syndrome with periodic apnea during hypersomnic stages--E.E.G. study. ( Carasso, R; Flechter, S; Rabey, JM; Streifler, M; Tupilsky, M; Vardi, J, 1978)
"Methylxanthine therapy is commonly used for apnea of prematurity but in the absence of adequate data on its efficacy and safety."5.12Long-term effects of caffeine therapy for apnea of prematurity. ( Barrington, KJ; Davis, P; Doyle, LW; Ohlsson, A; Roberts, RS; Schmidt, B; Solimano, A; Tin, W, 2007)
" Cardiac arrhythmias and central apnea have been proposed as mechanisms of sudden death in SUDEP."4.87Sudden unexpected death in epilepsy in childhood. ( Milroy, CM, 2011)
"Episodic apnea leading to asphyxia is a relatively common disorder of young children."4.77Sleep apnea in infancy and childhood. ( Thach, BT, 1985)
" Some significant consequences of altered autonomic function include convulsive apnea, abnormal sexual function, and potentially fatal effects on the cardiovascular system."4.77Autonomic nervous system and epilepsy. ( Wannamaker, BB, 1985)
" We investigated volume changes and the microstructure of the amygdala in people with epilepsy at varied risk for SUDEP since that structure can play a key role in triggering apnea and mediating blood pressure."4.31Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk. ( Allen, LA; Diehl, B; Duncan, JS; Harper, RM; Kassinopoulos, M; Kumar, R; Legouhy, A; Lemieux, L; Lhatoo, SD; Ogren, JA; Oliveira, JFA; Scott, C; Thom, M; Vos, SB; Winston, GP; Zhang, H, 2023)
" In addition, these mice developed baseline respiratory dysfunction prior to SUDEP, during which ictal apnea occurred long before terminal cardiac asystole."4.31Sudden Unexpected Death in Epilepsy and Respiratory Defects in a Mouse Model of DEPDC5-Related Epilepsy. ( Banerjee, R; Borna, NN; Cao, R; Hu, S; Kao, HY; Leventhal, DK; Li, P; Mir, MY; Parent, JM; Wang, S; Wang, Y; Yang, T; Yao, Y; Ziobro, J; Zylinski, M, 2023)
" The aim of this study was to evaluate the incidence of ictal apnea (IA) and related hypoxemia during seizures."4.12Ictal apnea: A prospective monocentric study in patients with epilepsy. ( Ballerini, A; Cioclu, MC; Giovannini, G; Giunta, L; Meletti, S; Micalizzi, E; Talami, F; Turchi, G; Vaudano, AE, 2022)
" In addition, pyridostigmine also resulted in resolution of apneas and improved respiratory status which suggests its potential therapeutic role in patients with PURA syndrome."4.12Hypotonic infant with PURA syndrome-related channelopathy successfully treated with pyridostigmine. ( Brooks, S; Crenshaw, M; DiBartolomeo, M; Geller, T; Iyadurai, S; Wyrebek, R, 2022)
"The primary cause of seizure-induced death for all mice was apnea, as (1) apnea began during a seizure and continued for tens of minutes until terminal asystole, and (2) death was prevented by mechanical ventilation."4.02Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ( Blizzard, EA; Goodkin, HP; Meisler, MH; Panchal, PS; Patel, MK; Richerson, GB; Saraf, P; Teran, FA; Wagley, PK; Wagnon, JL; Wengert, ER; Wenker, IC, 2021)
" Early-onset problems include excessive hiccups, hypotonia, hypersomnolence, hypothermia, feeding difficulties, recurrent apneas, epileptic seizures, and abnormal nonepileptic movements."4.02Expanding the PURA syndrome phenotype: A child with the recurrent PURA p.(Phe233del) pathogenic variant showing similarities with cutis laxa. ( Ciaccio, C; Cinquina, V; Colombi, M; Masson, R; Ritelli, M; Venturini, M, 2021)
"This case series aimed to characterize the clinical features, management, and outcomes of apnea in infants with trisomy 18."3.96Management of apnea in infants with trisomy 18. ( Fujiyoshi, J; Ichimiya, Y; Inoue, H; Ochiai, M; Ohga, S; Sakai, Y; Sanefuji, M; Sawano, T; Taira, R; Torio, M, 2020)
" When DORA administration increased heart rate, it also decreased heart rate variability, breathing frequency, and/or hypopnea-apnea."3.96Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin. ( Abel, PW; Aggarwal, A; Hallgren, J; Iyer, SH; Simeone, KA; Simeone, TA; Warren, TJ, 2020)
" However, the mechanisms underlying seizure-induced central apnea in pediatric epilepsy are unknown."3.96A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy. ( Ciliberto, MA; Dlouhy, BJ; Harmata, GI; Howard, MA; Kovach, CK; Rhone, AE; Richerson, GB; Steinschneider, M; Sullivan, AW; Tranel, D; Wemmie, JA, 2020)
"To determine the relationship between serum serotonin (5-HT) levels, ictal central apnea (ICA), and postconvulsive central apnea (PCCA) in epileptic seizures."3.91Postictal serotonin levels are associated with peri-ictal apnea. ( Bateman, LM; Devinsky, O; Diehl, B; Faingold, CL; Friedman, D; Hampson, JP; Harper, RM; Lacuey, N; Lhatoo, SD; Murugesan, A; Nei, M; Rani, MRS; Richerson, G; Sainju, RK; Schuele, S; Vilella, L, 2019)
"Increased breathing rate, apnea, and respiratory failure are associated with sudden unexpected death in epilepsy (SUDEP)."3.88Respiratory dysfunction progresses with age in Kcna1-null mice, a model of sudden unexpected death in epilepsy. ( Abel, PW; Aggarwal, A; Bockman, CS; Deodhar, M; Hallgren, J; Iyer, SH; Kansal, V; Matthews, SA; Netzel, L; Oldenburg, PJ; Simeone, KA; Simeone, TA, 2018)
"We report an 11-month-old boy with acetazolamide-responsive epileptic apnea and inherited glycosylphosphatidylinositol (GPI)-anchor deficiency who presented with decreased serum alkaline phosphatase associated with compound PIGT mutations."3.88Epileptic apnea in a patient with inherited glycosylphosphatidylinositol anchor deficiency and PIGT mutations. ( Adachi, Y; Ishiyama, A; Kinoshita, T; Kohashi, K; Matsumoto, N; Miya, K; Murakami, Y; Ohba, C; Saitsu, H; Sasaki, M; Sato, N; Sugai, K; Tanaka, T; Yuasa, S, 2018)
"We report the case of a child prospectively followed in our institution for a severe, neonatal onset epilepsy presenting with severe attacks of apnea that were not initially recognized as seizure since they were not associated with any abnormal movement and since interictal EEG was normal."3.85Heterogeneity of FHF1 related phenotype: Novel case with early onset severe attacks of apnea, partial mitochondrial respiratory chain complex II deficiency, neonatal onset seizures without neurodegeneration. ( Abidi, A; Cacciagli, P; Chabrol, B; Mignon-Ravix, C; Milh, M; Villard, L; Villeneuve, N, 2017)
" We found that central apnea and O2 desaturation occurred when seizures spread to the amygdala."3.81Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation. ( Buzza, C; Dlouhy, BJ; Gehlbach, BK; Granner, MA; Howard, MA; Kawasaki, H; Kreple, CJ; Oya, H; Richerson, GB; Welsh, MJ; Wemmie, JA, 2015)
"Many children with trisomy 18 have apneas from the neonatal period."3.81Apneas observed in trisomy 18 neonates should be differentiated from epileptic apneas. ( Asada, H; Fukasawa, T; Hattori, T; Kato, Y; Kubota, T; Matsusawa, K; Negoro, T; Tanaka, M, 2015)
"A 16-day-old infant developed several mild episodes of apnea that culminated in a severe cyanotic episode requiring resuscitation."3.75Severe apnea in an infant exposed to lamotrigine in breast milk. ( Aronsen, L; Nordmo, E; Småbrekke, L; Vorren, S; Wasland, K, 2009)
" We conclude that an abrupt increase in parasympathetic activity on the order of 5 times the background of parasympathetic tone can produce transient bradyarrhythmias, and increases on the order of 20 times can produce cardiac standstill, sometimes accompanied by apnea."3.75Vagus nerve stimulation-induced bradyarrhythmias in rats. ( Hotta, H; Kamran, H; Koizumi, K; Lazar, J; Orman, R; Shiba, K; Stewart, M, 2009)
"Apnea as an isolated manifestation of seizures is well described in neonates but is only occasionally observed in infants."3.74Apnea caused by mesial temporal lobe mass lesions in infants: report of 3 cases. ( Avellino, AM; Ellenbogen, RG; Kuratani, J; Miyagawa, T; Ojemann, JG; Saneto, RP; Sotero, M, 2007)
" Relatively simple interventions may be sufficient to interrupt potentially lethal events such as periictal suffocation or apnea."3.73Demystifying sudden unexplained death in epilepsy--are we close? ( So, EL, 2006)
"The hyperventilation maneuver caused a decrease in spontaneous ventilation in pilocarpine-treated and control rats."3.72Respiratory pattern in a rat model of epilepsy. ( Campos, RR; Mello, LE; Tolentino-Silva, FR, 2003)
"Two months-old girl with psychomotor retardation had aminophylline-resistant apnea attacks and was investigated by video-EEG recording."3.72[A case of infantile epileptic apnea with congenital brain anomaly]. ( Hamano, K; Iwasaki, N; Matsui, A; Ohto, T; Takahashi, M; Tanaka, R, 2003)
" In this animal model, the main difference between surviving animals and those that die during the seizure is apnea, with a precipitous fall in the partial pressure of oxygen (pO(2)) and a parallel elevation in the partial pressure of carbon dioxide (pCO(2)) recorded in nonsurvivors."3.69Epileptic sudden death: animal models. ( Simon, RP, 1997)
"ES in infants can manifest as ALTE and be accompanied by potentially life-threatening episodes of severe hypoxemia and apnea, despite a normal EEG between events."3.69Epileptic seizure-induced hypoxemia in infants with apparent life-threatening events. ( Boyd, SG; Hewertson, J; Neville, BG; Poets, CF; Samuels, MP; Southall, DP, 1994)
" In three cases where no cause was found the EA was not repeated, although apnea monitorization was necessary for several months because of the anxiety of the family."3.69[Clinical significance of episodes of apnea in babies]. ( Arcas, J; Barrio, MI; Leal, J; López-Martín, V; Martínez-Bermejo, A; Pascual-Castroviejo, I; Roche, C, 1997)
" Group 1 consisted of apparently healthy infants with near-miss SIDS episodes; Group 2 consisted of siblings of SIDS victims; and Group 3 consisted of neurologically suspect infants with apnea."3.67Cerebral cortical function in infants at risk for sudden infant death syndrome. ( Clancy, RR; Spitzer, AR, 1985)
"The authors report the observation of an infant who begins at the age of 7 months to present episodes of epileptic apnea with cyanosis, lost of consciousness, hypotony and sometimes ocular revulsion and distal myoclonia."3.67[Episodes of apnea in an infant: unusual forms of epileptic seizures]. ( Campistol, J; Estivill, E; Fernandez-Alvarez, E; Roger, J; Sanmarti, FX, 1985)
"A 33 year old male, suffering from Kleine-Levine syndrome associated with periods of apnea during the hypersomnic attacks, is reported."3.66Kleine-Levin syndrome with periodic apnea during hypersomnic stages--E.E.G. study. ( Carasso, R; Flechter, S; Rabey, JM; Streifler, M; Tupilsky, M; Vardi, J, 1978)
"However, just as many seizure types do not involve shaking, the differential diagnosis of intermittent shaking is wide and includes vasovagal syncope, cardiac disorders, concussive convulsions, psychogenic non-epileptic seizures, 'shaking transient ischaemic attacks', parasomnias, breath-holding attacks in children, hypoglycaemia and movement disorders."2.48All that shakes is not epilepsy. ( Hart, YM, 2012)
"SUDEP usually occurs when the seizures are not witnessed and often at night."2.47Sudden unexpected death in epilepsy. ( Shorvon, S; Tomson, T, 2011)
"Diagnosis of epileptic seizures is largely dependent on the clinical history."2.43Fits, faints and funny turns in children. ( Mackay, M, 2005)
"Once the clinical seizures were controlled, she was discharged to the sleep laboratory."1.72Obstructive and central sleep apnoea in a patient with medically intractable epilepsy. ( Balabanov, AJ; Lastra, AC; Schwartz, K, 2022)
"The possibility of occipital lobe epilepsy should be considered in school-age children presenting with acute visual hallucination followed by respiratory arrest."1.48Respiratory arrest at the onset of idiopathic childhood occipital epilepsy of Gastaut. ( Funata, K; Shike, T; Takahashi, T; Takenouchi, T; Yamashita, Y, 2018)
"Twenty-six (30."1.36Long-term prognosis for children with breath-holding spells. ( Knudsen, FU; Mathiasen, R; Olsen, AL; Rasmussen, NH, 2010)
"Apnoea as anisolated manidestation of seizures is well described in neonates but is only occasionally observed in infants."1.34[Apnoeic attacks as an isolated manifestation of epileptic seizures in infants]. ( Naĭdenov, A, 2007)
" The goal of treatment should therefore be seizure freedom, using the lowest effective number and dosage of AEDs."1.33Sudden unexpected death in epilepsy. Risk factors, possible mechanisms and prevention: a reappraisal. ( Bell, GS; Sander, JW, 2006)
"Syncopes were predominantly reflex asystolic (RAS), prolonged expiratory apnoea (cyanotic breath-holding spells), or of mixed or uncertain origin; there was one each of ear piercing and hair grooming vasovagal syncope and one of compulsive Valsalva."1.33Anoxic-epileptic seizures: observational study of epileptic seizures induced by syncopes. ( Horrocks, IA; Nechay, A; Stephenson, JB; Zuberi, SM, 2005)
"A boy, injured by lightning, had cardiopulmonary arrest."1.26Lightning injury: management of a case with ten-day survival. ( Anzinger, RE; Kravitz, H; Naidu, SH; Valaitis, J; Wasserman, MJ, 1977)

Research

Studies (88)

TimeframeStudies, this research(%)All Research%
pre-199025 (28.41)18.7374
1990's7 (7.95)18.2507
2000's27 (30.68)29.6817
2010's16 (18.18)24.3611
2020's13 (14.77)2.80

Authors

AuthorsStudies
Wyrebek, R1
DiBartolomeo, M1
Brooks, S1
Geller, T1
Crenshaw, M1
Iyadurai, S1
Micalizzi, E1
Vaudano, AE1
Ballerini, A1
Talami, F1
Giovannini, G1
Turchi, G1
Cioclu, MC1
Giunta, L1
Meletti, S1
Wenker, IC2
Boscia, AR1
Lewis, C1
Tariq, A1
Miralles, R1
Hanflink, JC1
Saraf, P2
Patel, MK2
Schwartz, K1
Lastra, AC1
Balabanov, AJ1
Legouhy, A1
Allen, LA1
Vos, SB1
Oliveira, JFA1
Kassinopoulos, M1
Winston, GP1
Duncan, JS1
Ogren, JA1
Scott, C1
Kumar, R1
Lhatoo, SD2
Thom, M1
Lemieux, L1
Harper, RM2
Zhang, H1
Diehl, B2
Kao, HY1
Yao, Y1
Yang, T1
Ziobro, J1
Zylinski, M1
Mir, MY1
Hu, S1
Cao, R1
Borna, NN1
Banerjee, R1
Parent, JM1
Wang, S1
Leventhal, DK1
Li, P1
Wang, Y1
Murugesan, A1
Rani, MRS1
Vilella, L1
Lacuey, N1
Hampson, JP1
Faingold, CL2
Friedman, D1
Devinsky, O1
Sainju, RK1
Schuele, S1
Nei, M1
Bateman, LM1
Richerson, G1
Taira, R1
Inoue, H1
Sawano, T1
Fujiyoshi, J1
Ichimiya, Y1
Torio, M1
Sanefuji, M1
Ochiai, M1
Sakai, Y1
Ohga, S1
Iyer, SH2
Aggarwal, A2
Warren, TJ1
Hallgren, J2
Abel, PW2
Simeone, TA2
Simeone, KA2
Rhone, AE1
Kovach, CK1
Harmata, GI1
Sullivan, AW1
Tranel, D1
Ciliberto, MA1
Howard, MA2
Richerson, GB4
Steinschneider, M1
Wemmie, JA2
Dlouhy, BJ2
Zawadzka, M1
Matheisel, A1
Konieczna, S1
Mazurkiewicz-Bełdzińska, M1
Kim, HJ1
Yang, D1
Kang, HC1
Cinquina, V1
Ciaccio, C1
Venturini, M1
Masson, R1
Ritelli, M1
Colombi, M1
Teran, FA1
Wengert, ER1
Wagley, PK1
Panchal, PS1
Blizzard, EA1
Wagnon, JL1
Goodkin, HP1
Meisler, MH1
Villeneuve, N1
Abidi, A1
Cacciagli, P1
Mignon-Ravix, C1
Chabrol, B1
Villard, L1
Milh, M1
Kohashi, K1
Ishiyama, A1
Yuasa, S1
Tanaka, T1
Miya, K1
Adachi, Y1
Sato, N1
Saitsu, H1
Ohba, C1
Matsumoto, N1
Murakami, Y1
Kinoshita, T1
Sugai, K1
Sasaki, M1
Funata, K1
Shike, T1
Takenouchi, T1
Yamashita, Y1
Takahashi, T1
Bockman, CS1
Kansal, V1
Netzel, L1
Matthews, SA1
Deodhar, M1
Oldenburg, PJ1
Loddenkemper, T1
Holze, N1
Baalen, AV1
Stephani, U1
Helbig, I1
Muhle, H1
Younes, TB1
Benrhouma, H1
Klaa, H1
Rouissi, A1
Chaabouni, M1
Kraoua, I1
Youssef-Turki, IB1
Fukasawa, T1
Kubota, T1
Tanaka, M1
Asada, H1
Matsusawa, K1
Hattori, T1
Kato, Y1
Negoro, T2
Gehlbach, BK1
Kreple, CJ1
Kawasaki, H1
Oya, H1
Buzza, C1
Granner, MA1
Welsh, MJ1
Boison, D1
Ryvlin, P1
Khurana, D1
Valencia, I1
Kruthiventi, S1
Gracely, E1
Melvin, J1
Legido, A1
Kothare, S1
Bonkowsky, JL1
Guenther, E1
Filloux, FM1
Srivastava, R1
DiMario, FJ2
Couzin, J1
Tezer, FI1
Rémi, J1
Noachtar, S1
Hotta, H1
Lazar, J1
Orman, R1
Koizumi, K1
Shiba, K1
Kamran, H1
Stewart, M1
Nordmo, E1
Aronsen, L1
Wasland, K1
Småbrekke, L1
Vorren, S1
Simon, RP1
Sharma, VK1
Teoh, HL1
Chan, BP1
Olsen, AL1
Mathiasen, R1
Rasmussen, NH1
Knudsen, FU1
Milroy, CM1
Shorvon, S1
Tomson, T1
Hart, YM1
Sites, BD1
Blike, G1
Cravero, J1
Andeweg, S1
Beach, M1
Campos, RR1
Tolentino-Silva, FR1
Mello, LE1
MEYER, JS2
ISHIKAWA, S1
LEE, TK1
Ohto, T1
Iwasaki, N1
Takahashi, M1
Tanaka, R1
Hamano, K1
Matsui, A1
Balling, K1
Uldall, P1
O'Regan, ME1
Brown, JK1
Verrotti, A1
Salladini, C1
Trotta, D1
di Corcia, G1
Chiarelli, F1
Horrocks, IA1
Nechay, A1
Stephenson, JB1
Zuberi, SM1
Mackay, M1
Goyal, M1
Avery, JA1
Kharatishvili, I1
Nissinen, JP1
McIntosh, TK1
Pitkänen, A1
Bell, GS1
Sander, JW3
So, EL1
Naĭdenov, A1
Miyagawa, T1
Sotero, M1
Avellino, AM1
Kuratani, J1
Saneto, RP1
Ellenbogen, RG1
Ojemann, JG1
Schmidt, B1
Roberts, RS1
Davis, P1
Doyle, LW1
Barrington, KJ1
Ohlsson, A1
Solimano, A1
Tin, W1
Aurlien, D1
Taubøll, E1
Gjerstad, L1
Giroud, M1
Gouyon, JB1
Sandre, D1
Nivelon, JL1
Alison, M1
Sykes, P1
Watanabe, K1
Hara, K1
Hakamada, S1
Sugiura, M1
Matsumoto, A1
Maehara, M1
Walls, TJ1
Newman, PK1
Cumming, WJ1
Hewertson, J1
Poets, CF1
Samuels, MP1
Boyd, SG1
Neville, BG2
Southall, DP1
Nashef, L2
Walker, F1
Allen, P1
Shorvon, SD1
Fish, DR1
Martínez-Bermejo, A1
Roche, C1
López-Martín, V1
Arcas, J1
Leal, J1
Barrio, MI1
Pascual-Castroviejo, I1
van Putten, MJ1
Bosman-Vermeeren, JM1
Brouwer, OF2
Tamura, F1
Shishikura, J1
Mukai, Y1
Kaneko, Y1
Langan, Y1
Ramelli, GP1
Donati, F1
Bianchetti, M1
Vassella, F1
Mattie-Luksic, M1
Javornisky, G1
Clark, M1
Carr, L1
Reilly, S1
Lamberg, L1
Vardi, J1
Flechter, S1
Tupilsky, M1
Rabey, JM1
Carasso, R1
Streifler, M1
Kravitz, H1
Wasserman, MJ1
Valaitis, J1
Anzinger, RE1
Naidu, SH1
Bajer, A1
Nedbal, J1
Danĕk, V1
Sanmarti, FX1
Estivill, E1
Campistol, J1
Roger, J1
Fernandez-Alvarez, E1
Peters, AC1
Wannamaker, BB1
Thach, BT1
Clancy, RR1
Spitzer, AR1
Wässer, S1
Bergmann, L1
Andréu, S1
Gotoh, F1
Favale, E1
Feuerstein, J2
Manz, JM1
Kurtz, D2
Isch-Treussard, C2
Tempe, JD2
Prichard, JS1
Gsell, S1
Ossenkopp, G1
Weigeldt, HD1
Fitzhardinge, PM1
Ramsay, M1
Snyder, CH1
Pelc, S1
Mutani, R1
Fariello, R1
Accatino, G1
Brocchi, G1
Mantz, JM1
Lansky, L1
Benatti, C1
Foschi, F1
Cavazzuti, GB1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Controlled Trial of Inhalation of Low Concentration of CO2 in Preterm Infants Not Responding to Caffeine for the Treatment of Apnea of Prematurity[NCT01911182]Phase 2/Phase 37 participants (Actual)Interventional2011-10-31Terminated (stopped due to Low recruitment rate)
Efficacy and Safety of Methylxanthines in Very Low Birthweight Infants[NCT00182312]Phase 32,000 participants (Anticipated)Interventional1999-10-31Completed
Long-Term Effects On Sleep Of Methylxanthine Therapy For Apnea Of Prematurity[NCT01020357]Phase 3201 participants (Actual)Interventional2009-11-30Completed
[NCT01066728]Phase 2/Phase 387 participants (Actual)Interventional2001-08-31Completed
A Randomized, Placebo-controlled Trial of Early Caffeine in Preterm Neonates[NCT03086473]Phase 424 participants (Actual)Interventional2017-02-01Active, not recruiting
Pharmacokinetics (PK) and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia[NCT05295784]Phase 118 participants (Anticipated)Interventional2024-06-30Not yet recruiting
Preliminary Testing of a Novel Device to Detect Epileptic Seizures[NCT02286271]117 participants (Actual)Observational2015-01-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for apnea and Epilepsy

ArticleYear
Early Life Epilepsy and Episodic Apnea Revealing an ATP1A3 Mutation: Report of a Pediatric Case and Literature Review.
    Neuropediatrics, 2018, Volume: 49, Issue:5

    Topics: Apnea; Epilepsy; Humans; Infant; Male; Sodium-Potassium-Exchanging ATPase

2018
From unwitnessed fatality to witnessed rescue: Pharmacologic intervention in sudden unexpected death in epilepsy.
    Epilepsia, 2016, Volume: 57 Suppl 1

    Topics: Adenosine; Apnea; Brain Stem; Death, Sudden; Epilepsy; Humans; Hypoventilation; Narcotic Antagonists

2016
Sudden unexpected death in epilepsy in childhood.
    Forensic science, medicine, and pathology, 2011, Volume: 7, Issue:4

    Topics: Apnea; Arrhythmias, Cardiac; Brain; Cause of Death; Child; Death, Sudden; Diagnosis, Differential; D

2011
Sudden unexpected death in epilepsy.
    Lancet (London, England), 2011, Dec-10, Volume: 378, Issue:9808

    Topics: Age Distribution; Anticonvulsants; Apnea; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Causalit

2011
All that shakes is not epilepsy.
    The journal of the Royal College of Physicians of Edinburgh, 2012, Volume: 42, Issue:2

    Topics: Apnea; Diagnosis, Differential; Epilepsy; Epilepsy, Post-Traumatic; Heart Diseases; Humans; Hypoglyc

2012
Fits, faints and funny turns in children.
    Australian family physician, 2005, Volume: 34, Issue:12

    Topics: Adolescent; Apnea; Child; Child, Preschool; Diagnosis, Differential; Epilepsy; Family Practice; Huma

2005
Paroxysmal disorders and the autonomic nervous system in pediatrics.
    American journal of electroneurodiagnostic technology, 2005, Volume: 45, Issue:4

    Topics: Apnea; Autonomic Nervous System; Autonomic Nervous System Diseases; Child; Electroencephalography; E

2005
[Central apnea in newborns].
    Nederlands tijdschrift voor geneeskunde, 1999, Feb-27, Volume: 143, Issue:9

    Topics: Acetazolamide; Anticonvulsants; Apnea; Arnold-Chiari Malformation; Diagnosis, Differential; DiGeorge

1999
Autonomic nervous system and epilepsy.
    Epilepsia, 1985, Volume: 26 Suppl 1

    Topics: Adult; Animals; Apnea; Autonomic Nervous System; Cardiovascular System; Cats; Cerebral Cortex; Child

1985
Sleep apnea in infancy and childhood.
    The Medical clinics of North America, 1985, Volume: 69, Issue:6

    Topics: Apnea; Child; Child, Preschool; Eating; Epilepsy; Gastroesophageal Reflux; Heart Rate; Humans; Hypov

1985
Convulsive disorders in children: some notes on the diagnosis and treatment.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:4

    Topics: Apnea; Child; Child, Preschool; Epilepsy; Fever; Heart Arrest; Humans; Migraine Disorders; Seizures;

1974

Trials

1 trial available for apnea and Epilepsy

ArticleYear
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007
Long-term effects of caffeine therapy for apnea of prematurity.
    The New England journal of medicine, 2007, Nov-08, Volume: 357, Issue:19

    Topics: Apnea; Body Size; Caffeine; Central Nervous System Stimulants; Cerebral Palsy; Citrates; Development

2007

Other Studies

76 other studies available for apnea and Epilepsy

ArticleYear
Hypotonic infant with PURA syndrome-related channelopathy successfully treated with pyridostigmine.
    Neuromuscular disorders : NMD, 2022, Volume: 32, Issue:2

    Topics: Acetylcholinesterase; Apnea; Channelopathies; DNA-Binding Proteins; Epilepsy; Humans; Infant; Intell

2022
Ictal apnea: A prospective monocentric study in patients with epilepsy.
    European journal of neurology, 2022, Volume: 29, Issue:12

    Topics: Apnea; Electroencephalography; Epilepsy; Epilepsy, Generalized; Humans; Hypoxia; Prospective Studies

2022
Forebrain epileptiform activity is not required for seizure-induced apnea in a mouse model of
    Frontiers in neural circuits, 2022, Volume: 16

    Topics: Animals; Apnea; Clozapine; Designer Drugs; Disease Models, Animal; Epilepsy; Ligands; Mice; Mice, Tr

2022
Obstructive and central sleep apnoea in a patient with medically intractable epilepsy.
    BMJ case reports, 2022, Sep-28, Volume: 15, Issue:9

    Topics: Apnea; Death, Sudden; Drug Resistant Epilepsy; Electroencephalography; Epilepsy; Female; Humans; Sei

2022
Volumetric and microstructural abnormalities of the amygdala in focal epilepsy with varied levels of SUDEP risk.
    Epilepsy research, 2023, Volume: 192

    Topics: Amygdala; Apnea; Diffusion Tensor Imaging; Epilepsies, Partial; Epilepsy; Humans; Sudden Unexpected

2023
Sudden Unexpected Death in Epilepsy and Respiratory Defects in a Mouse Model of DEPDC5-Related Epilepsy.
    Annals of neurology, 2023, Volume: 94, Issue:5

    Topics: Animals; Apnea; Death, Sudden; Epilepsies, Partial; Epilepsy; GTPase-Activating Proteins; Mice; Seiz

2023
Postictal serotonin levels are associated with peri-ictal apnea.
    Neurology, 2019, 10-08, Volume: 93, Issue:15

    Topics: Adolescent; Adult; Aged; Apnea; Death, Sudden; Electroencephalography; Epilepsy; Female; Humans; Mal

2019
Management of apnea in infants with trisomy 18.
    Developmental medicine and child neurology, 2020, Volume: 62, Issue:7

    Topics: Apnea; Epilepsy; Female; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Male; Outc

2020
Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin.
    Epilepsia, 2020, Volume: 61, Issue:3

    Topics: Animals; Apnea; Bradycardia; Epilepsy; Heart Rate; Hypothalamic Area, Lateral; Hypoxia; Kv1.1 Potass

2020
A human amygdala site that inhibits respiration and elicits apnea in pediatric epilepsy.
    JCI insight, 2020, 03-26, Volume: 5, Issue:6

    Topics: Adolescent; Amygdala; Apnea; Child; Child, Preschool; Electrocorticography; Epilepsy; Female; Humans

2020
Autonomic seizure with prominent apnea in patient with SCN8A-related epileptic encephalopathy.
    Epilepsy research, 2020, Volume: 167

    Topics: Apnea; Epilepsy; Humans; NAV1.6 Voltage-Gated Sodium Channel; Seizures

2020
Re: Autonomic seizure with prominent apnea in patient with SCN8A-related epileptic encephalopathy.
    Epilepsy research, 2020, Volume: 167

    Topics: Apnea; Epilepsy; Humans; NAV1.6 Voltage-Gated Sodium Channel; Seizures

2020
Expanding the PURA syndrome phenotype: A child with the recurrent PURA p.(Phe233del) pathogenic variant showing similarities with cutis laxa.
    Molecular genetics & genomic medicine, 2021, Volume: 9, Issue:1

    Topics: Apnea; Child, Preschool; Cutis Laxa; Developmental Disabilities; Diagnosis, Differential; DNA-Bindin

2021
Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy.
    Annals of neurology, 2021, Volume: 89, Issue:5

    Topics: Animals; Apnea; Convulsants; Diaphragm; Electroencephalography; Electromyography; Epilepsy; Female;

2021
Heterogeneity of FHF1 related phenotype: Novel case with early onset severe attacks of apnea, partial mitochondrial respiratory chain complex II deficiency, neonatal onset seizures without neurodegeneration.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2017, Volume: 21, Issue:5

    Topics: Apnea; Electroencephalography; Electron Transport Complex II; Epilepsy; Fibroblast Growth Factors; H

2017
Epileptic apnea in a patient with inherited glycosylphosphatidylinositol anchor deficiency and PIGT mutations.
    Brain & development, 2018, Volume: 40, Issue:1

    Topics: Abnormalities, Multiple; Acyltransferases; Apnea; Atrophy; Developmental Disabilities; Epilepsy; Gly

2018
Respiratory arrest at the onset of idiopathic childhood occipital epilepsy of Gastaut.
    Brain & development, 2018, Volume: 40, Issue:1

    Topics: Anticonvulsants; Apnea; Child; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Halluc

2018
Respiratory dysfunction progresses with age in Kcna1-null mice, a model of sudden unexpected death in epilepsy.
    Epilepsia, 2018, Volume: 59, Issue:2

    Topics: Animals; Apnea; Bronchoconstrictor Agents; Death, Sudden; Disease Models, Animal; Disease Progressio

2018
Conscious control of breathing: A key to prevention of sudden unexpected death in epilepsy?
    Annals of neurology, 2018, Volume: 83, Issue:3

    Topics: Amygdala; Apnea; Attention; Death, Sudden; Epilepsy; Humans

2018
Variants in the ATP1A3 Gene Mutations within Severe Apnea Starting in Early Infancy: An Observational Study of Two Cases with a Possible Relation to Epileptic Activity.
    Neuropediatrics, 2018, Volume: 49, Issue:5

    Topics: Age of Onset; Apnea; Child, Preschool; Developmental Disabilities; Epilepsy; Female; Humans; Sodium-

2018
Apneas observed in trisomy 18 neonates should be differentiated from epileptic apneas.
    American journal of medical genetics. Part A, 2015, Volume: 167A, Issue:3

    Topics: Apnea; Child, Preschool; Chromosomes, Human, Pair 18; Diagnosis, Differential; Electroencephalograph

2015
Breathing Inhibited When Seizures Spread to the Amygdala and upon Amygdala Stimulation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jul-15, Volume: 35, Issue:28

    Topics: Amygdala; Analysis of Variance; Apnea; Brain Mapping; Electric Stimulation; Electroencephalography;

2015
Correspondence on "electroencephalography (EEG) with ocular compression in the diagnosis of breath-holding spells or syncope".
    Journal of child neurology, 2008, Volume: 23, Issue:6

    Topics: Apnea; Child; Child, Preschool; Cyanosis; Diagnosis, Differential; Electrocardiography; Electroencep

2008
Death, child abuse, and adverse neurological outcome of infants after an apparent life-threatening event.
    Pediatrics, 2008, Volume: 122, Issue:1

    Topics: Apnea; Child Abuse; Critical Illness; Cyanosis; Developmental Disabilities; Epilepsy; Female; Humans

2008
Apparent life-threatening events: so what happens next?
    Pediatrics, 2008, Volume: 122, Issue:1

    Topics: Apnea; Critical Illness; Cyanosis; Developmental Disabilities; Epilepsy; Gastroesophageal Reflux; Hu

2008
Epilepsy. When death strikes without warning.
    Science (New York, N.Y.), 2008, Jul-04, Volume: 321, Issue:5885

    Topics: Animals; Anticonvulsants; Apnea; Brain; Death, Sudden; Electroencephalography; Epilepsy; Epilepsy, T

2008
Ictal apnea of epileptic origin.
    Neurology, 2009, Mar-03, Volume: 72, Issue:9

    Topics: Adult; Apnea; Diagnosis, Differential; Electroencephalography; Epilepsy; Female; Humans; Middle Aged

2009
Vagus nerve stimulation-induced bradyarrhythmias in rats.
    Autonomic neuroscience : basic & clinical, 2009, Dec-03, Volume: 151, Issue:2

    Topics: Animals; Apnea; Autonomic Nervous System Diseases; Blood Pressure; Bradycardia; Death, Sudden, Cardi

2009
Severe apnea in an infant exposed to lamotrigine in breast milk.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:11

    Topics: Adult; Apnea; Breast Feeding; Epilepsy; Female; Humans; Infant, Newborn; Lamotrigine; Male; Milk, Hu

2009
Epileptic sudden death: animal models.
    Epilepsia, 1997, Volume: 38, Issue:11 Suppl

    Topics: Animals; Apnea; Death, Sudden; Disease Models, Animal; Epilepsy; Humans; Hypertension, Pulmonary; Pu

1997
Cerebral vasomotor reactivity in epilepsy patients.
    Journal of neurology, 2010, Volume: 257, Issue:9

    Topics: Apnea; Cerebral Arteries; Cerebrovascular Circulation; Epilepsy; Humans; Hypercapnia; Inhalation; Va

2010
Long-term prognosis for children with breath-holding spells.
    Danish medical bulletin, 2010, Volume: 57, Issue:11

    Topics: Apnea; Attention; Child; Child Behavior; Child, Preschool; Cyanosis; Educational Status; Epilepsy; F

2010
Single-dose caudal anaesthesia for two infants undergoing diagnostic brain magnetic resonance imaging: high risk and nonhigh risk.
    Paediatric anaesthesia, 2003, Volume: 13, Issue:2

    Topics: Anesthesia, Caudal; Anesthetics, Local; Apnea; Brain; Bupivacaine; Craniofacial Abnormalities; Epile

2003
Respiratory pattern in a rat model of epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:5

    Topics: Animals; Apnea; Blood Pressure; Chemoreceptor Cells; Convulsants; Epilepsy; Heart Rate; Hyperventila

2003
ELECTROMAGNETIC MEASUREMENT OF INTERNAL JUGULAR VENOUS FLOW IN THE MONKEY; EFFECT OF EPILEPSY AND OTHER PROCEDURES.
    Journal of neurosurgery, 1964, Volume: 21

    Topics: Anesthesia; Animals; Apnea; Bemegride; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat

1964
[A case of infantile epileptic apnea with congenital brain anomaly].
    No to hattatsu = Brain and development, 2003, Volume: 35, Issue:6

    Topics: Apnea; Brain; Electroencephalography; Epilepsy; Female; Humans; Infant; Intellectual Disability; Val

2003
[Apnea as a primary manifestation of epilepsy].
    Ugeskrift for laeger, 2004, Oct-25, Volume: 166, Issue:44

    Topics: Apnea; Epilepsy; Humans; Infant; Male

2004
Abnormalities in cardiac and respiratory function observed during seizures in childhood.
    Developmental medicine and child neurology, 2005, Volume: 47, Issue:1

    Topics: Adolescent; Apnea; Blood Pressure; Child; Child, Preschool; Cohort Studies; Electrocardiography; Ele

2005
Ictal cardiorespiratory arrest in Panayiotopoulos syndrome.
    Neurology, 2005, May-24, Volume: 64, Issue:10

    Topics: Apnea; Autonomic Nervous System; Autonomic Nervous System Diseases; Cardiopulmonary Resuscitation; C

2005
Anoxic-epileptic seizures: observational study of epileptic seizures induced by syncopes.
    Archives of disease in childhood, 2005, Volume: 90, Issue:12

    Topics: Age of Onset; Anticonvulsants; Apnea; Child; Child, Preschool; Electrocardiography; Electroencephalo

2005
A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats.
    Neuroscience, 2006, Jun-30, Volume: 140, Issue:2

    Topics: Animals; Apnea; Brain; Brain Concussion; Cell Death; Dentate Gyrus; Disease Models, Animal; Electroe

2006
Sudden unexpected death in epilepsy. Risk factors, possible mechanisms and prevention: a reappraisal.
    Acta neurologica Taiwanica, 2006, Volume: 15, Issue:2

    Topics: Adult; Apnea; Arrhythmias, Cardiac; Death, Sudden; Electroencephalography; Epilepsy; Female; Heart R

2006
Demystifying sudden unexplained death in epilepsy--are we close?
    Epilepsia, 2006, Volume: 47 Suppl 1

    Topics: Age Factors; Animals; Apnea; Asphyxia; Comorbidity; Death, Sudden; Disease Models, Animal; Epilepsy;

2006
[Apnoeic attacks as an isolated manifestation of epileptic seizures in infants].
    Akusherstvo i ginekologiia, 2007, Volume: 46, Issue:1

    Topics: Apnea; Electroencephalography; Epilepsy; Humans; Infant; Neurologic Examination; Seizures

2007
Apnea caused by mesial temporal lobe mass lesions in infants: report of 3 cases.
    Journal of child neurology, 2007, Volume: 22, Issue:9

    Topics: Apnea; Astrocytoma; Brain Neoplasms; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Fema

2007
An insufficient effect of lamotrigine leading to fatal seizures.
    Acta neurologica Scandinavica, 2008, Volume: 117, Issue:4

    Topics: Acidosis; Age Factors; Anticonvulsants; Apnea; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Re

2008
[Epileptic apneas in the neonatal period].
    Archives francaises de pediatrie, 1983, Volume: 40, Issue:9

    Topics: Apnea; Electroencephalography; Epilepsy; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases;

1983
Severe respiratory depression following pentazocine and methohexitone. A case report.
    SAAD digest, 1982, Volume: 5, Issue:4

    Topics: Adult; Anesthesia, Dental; Apnea; Epilepsy; Female; Humans; Methohexital; Pentazocine

1982
Seizures with apnea in children.
    Pediatrics, 1982, Volume: 70, Issue:1

    Topics: Apnea; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; Male

1982
Recurrent apnoeic attacks as a manifestation of epilepsy.
    Postgraduate medical journal, 1981, Volume: 57, Issue:671

    Topics: Adult; Apnea; Epilepsy; Female; Humans; Recurrence

1981
Epileptic seizure-induced hypoxemia in infants with apparent life-threatening events.
    Pediatrics, 1994, Volume: 94, Issue:2 Pt 1

    Topics: Apnea; Blood Gas Monitoring, Transcutaneous; Electrocardiography; Electroencephalography; Epilepsy;

1994
Apnoea and bradycardia during epileptic seizures: relation to sudden death in epilepsy.
    Journal of neurology, neurosurgery, and psychiatry, 1996, Volume: 60, Issue:3

    Topics: Adolescent; Adult; Apnea; Bradycardia; Death, Sudden; Epilepsy; Feasibility Studies; Female; Heart R

1996
[Clinical significance of episodes of apnea in babies].
    Revista de neurologia, 1997, Volume: 25, Issue:140

    Topics: Apnea; Electroencephalography; Epilepsy; Humans; Infant; Infant, Newborn; Sudden Infant Death

1997
Arterial oxygen saturation in severely disabled people: effect of oral feeding in the sitting position.
    Dysphagia, 1999,Fall, Volume: 14, Issue:4

    Topics: Adolescent; Adult; Airway Obstruction; Apnea; Blood Circulation; Cerebral Palsy; Cough; Disabled Per

1999
Sudden unexpected death in epilepsy: a series of witnessed deaths.
    Journal of neurology, neurosurgery, and psychiatry, 2000, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Apnea; Arrhythmias, Cardiac; Chronic Disease; Death, Sudden; Epilepsy; Female; Hu

2000
Apnoeic attacks as an isolated manifestation of epileptic seizures in infants.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 1998, Volume: 2, Issue:4

    Topics: Apnea; Atrophy; Diagnosis, Differential; Electroencephalography; Epilepsy; Female; Frontal Lobe; Hea

1998
Assessment of stress in mothers of children with severe breath-holding spells.
    Pediatrics, 2000, Volume: 106, Issue:1 Pt 1

    Topics: Analysis of Variance; Apnea; Case-Control Studies; Child; Child, Preschool; Epilepsy; Female; Humans

2000
Worster-Drought syndrome, a mild tetraplegic perisylvian cerebral palsy. Review of 47 cases.
    Brain : a journal of neurology, 2000, Volume: 123 ( Pt 10)

    Topics: Adolescent; Apnea; Apraxias; Bulbar Palsy, Progressive; Cerebral Cortex; Child; Child, Preschool; Co

2000
Sleep disorders, often unrecognized, complicate many physical illnesses.
    JAMA, 2000, Nov-01, Volume: 284, Issue:17

    Topics: Adult; Alzheimer Disease; Apnea; Child; Epilepsy; Gastrointestinal Diseases; Humans; Kidney Diseases

2000
Kleine-Levin syndrome with periodic apnea during hypersomnic stages--E.E.G. study.
    Journal of neural transmission, 1978, Volume: 43, Issue:2

    Topics: Adult; Apnea; Carbon Dioxide; Diencephalon; Disorders of Excessive Somnolence; Electroencephalograph

1978
Lightning injury: management of a case with ten-day survival.
    American journal of diseases of children (1960), 1977, Volume: 131, Issue:4

    Topics: Adolescent; Apnea; Arrhythmias, Cardiac; Brain Edema; Electric Injuries; Epilepsy; Gastrointestinal

1977
[The significance of loads with manifestations of the Valsalva manoeuvre and apnoea in epilepsy (author's transl)].
    Casopis lekaru ceskych, 1977, Jun-17, Volume: 116, Issue:24

    Topics: Apnea; Electroencephalography; Epilepsy; Humans; Valsalva Maneuver

1977
[Episodes of apnea in an infant: unusual forms of epileptic seizures].
    Revue d'electroencephalographie et de neurophysiologie clinique, 1985, Volume: 14, Issue:4

    Topics: Adrenocorticotropic Hormone; Apnea; Developmental Disabilities; Diagnosis, Differential; Electroence

1985
[Breath-holding spells].
    Nederlands tijdschrift voor geneeskunde, 1988, Apr-23, Volume: 132, Issue:17

    Topics: Apnea; Child, Preschool; Diagnosis, Differential; Epilepsy; Humans; Parent-Child Relations; Parents;

1988
Cerebral cortical function in infants at risk for sudden infant death syndrome.
    Annals of neurology, 1985, Volume: 18, Issue:1

    Topics: Apnea; Cerebral Cortex; Child, Preschool; Electroencephalography; Epilepsy; Humans; Infant; Infant,

1985
[Clinical anamnestic findings in children with respiratory affect seizures].
    Kinderarztliche Praxis, 1985, Volume: 53, Issue:10

    Topics: Affect; Apnea; Child, Preschool; Crying; Epilepsy; Humans; Infant

1985
Cerebral metabolism during epileptic seizures in man.
    Electroencephalography and clinical neurophysiology, 1966, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Apnea; Bemegride; Blood Flow Velocity; Brain; Cerebrovascular Circulation;

1966
Epilepsy with respiratory changes including prolonged apnea during severe digitalis intoxication.
    Electroencephalography and clinical neurophysiology, 1968, Volume: 25, Issue:1

    Topics: Apnea; Digitalis Glycosides; Electroencephalography; Epilepsy; Humans; Infant; Respiratory Insuffici

1968
[Apnea and heart arrest following distraneurin therapy. Clinical, neurophysiological and neuropathological aspects].
    Der Nervenarzt, 1972, Volume: 43, Issue:12

    Topics: Adult; Apnea; Basal Ganglia; Cerebral Cortex; Chlormethiazole; Drug Synergism; Electroencephalograph

1972
The improving outlook for the small prematurely born infant.
    Developmental medicine and child neurology, 1973, Volume: 15, Issue:4

    Topics: Apnea; Asphyxia Neonatorum; Attention Deficit Disorder with Hyperactivity; Birth Weight; Child; Chil

1973
Conditions that simuate epilepsy in children: some bedside observations and reflections.
    Clinical pediatrics, 1972, Volume: 11, Issue:8

    Topics: Apnea; Child; Child, Preschool; Diagnosis, Differential; Electrocardiography; Epilepsy; Female; Hear

1972
[Sobbing breathholding spasms].
    Revue neurologique, 1970, Volume: 123, Issue:1

    Topics: Age Factors; Apnea; Crying; Electroencephalography; Epilepsy; Humans; Infant

1970
[Anoxic syncope or epileptic crisis? Description of a clinical case].
    Minerva medica, 1971, Jun-23, Volume: 62, Issue:50

    Topics: Aged; Apnea; Bradycardia; Diagnosis, Differential; Electrocardiography; Electroencephalography; Elec

1971
[Epilepsy with respiratory manifestations with prolonged apneas in the course of a massive digitalis poisoning].
    Revue neurologique, 1967, Volume: 117, Issue:3

    Topics: Apnea; Brain; Digitalis Glycosides; Electroencephalography; Epilepsy; Female; Heart Diseases; Humans

1967
Breath-holding spells and syncope.
    Postgraduate medicine, 1969, Volume: 46, Issue:2

    Topics: Apnea; Child, Preschool; Diagnosis, Differential; Epilepsy; Humans; Infant; Respiration; Syncope

1969
[Affective respiratory spasms in the infantile age: neurological and electroencephalographic aspects. I].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1966, Dec-31, Volume: 90, Issue:6

    Topics: Apnea; Brain Diseases; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; Infant; M

1966