papaverine has been researched along with Epilepsy in 12 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
Excerpt | Relevance | Reference |
---|---|---|
"Papaverine is a vasodilator agent that is an opium alkaloid." | 1.48 | Proconvulsant Effect of Papaverine on Penicillin-Induced Epileptiform Activity in Rats. ( Cokluk, C; Him, A; Kocacan, SE; Kuruoglu, E; Marangoz, AH; Marangoz, C, 2018) |
"The grave course of epilepsy is associated with a decrease of the LCBF on the side of the focus." | 1.28 | [Changes in cerebral blood circulation and their correction in the interparoxysmal period of epilepsy]. ( Shestakov, VV; Shutov, AA, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (83.33) | 18.7374 |
1990's | 1 (8.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (8.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Marangoz, AH | 1 |
Kocacan, SE | 1 |
Him, A | 1 |
Kuruoglu, E | 1 |
Cokluk, C | 1 |
Marangoz, C | 1 |
SEREISKII, MIa | 1 |
USPENSKAIA, MA | 1 |
WIRTH, L | 1 |
MEYER, JS | 1 |
ISHIKAWA, S | 1 |
LEE, TK | 1 |
MERCIER, J | 1 |
RUSSEK, HL | 1 |
ZOHMAN, BL | 1 |
Shutov, AA | 2 |
Pleshkova, NM | 1 |
Shestakov, VV | 2 |
Pozdniakov, VS | 1 |
Vailly, B | 1 |
Rougeron, G | 1 |
Weill, A | 1 |
Bollack, C | 1 |
Hadjiev, D | 1 |
1 review available for papaverine and Epilepsy
Article | Year |
---|---|
Impedance methods for investigation of cerebral circulation.
Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carbon Dioxide; Carotid Artery Diseases; Cerebral | 1972 |
11 other studies available for papaverine and Epilepsy
Article | Year |
---|---|
Proconvulsant Effect of Papaverine on Penicillin-Induced Epileptiform Activity in Rats.
Topics: Animals; Convulsants; Epilepsy; Female; Papaverine; Penicillins; Rats; Rats, Wistar; Seizures; Vasod | 2018 |
[New method of therapy of epilepsy].
Topics: Barbiturates; Bromides; Epilepsy; Humans; Hypnotics and Sedatives; Papaverine | 1955 |
[Result of the treatment of epilepsy in children with Sereiskii's mixture].
Topics: Barbiturates; Bromides; Child; Epilepsy; Humans; Hypnotics and Sedatives; Papaverine | 1955 |
Papaverine hydrochloride in status epilepticus.
Topics: Epilepsy; Humans; Papaverine; Status Epilepticus | 1956 |
ELECTROMAGNETIC MEASUREMENT OF INTERNAL JUGULAR VENOUS FLOW IN THE MONKEY; EFFECT OF EPILEPSY AND OTHER PROCEDURES.
Topics: Anesthesia; Animals; Apnea; Bemegride; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulat | 1964 |
[Effect on audiogenic seizure of white rat of some natural or synthetic alkaloids derived from opium: morphine, dihydro-oxycodeinone, papaverine].
Topics: Alkaloids; Animals; Epilepsy; Epilepsy, Reflex; Morphine; Opium; Papaverine; Rats; Seizures | 1950 |
Papaverine in epilepsy.
Topics: Epilepsy; Humans; Papaverine | 1949 |
[Disorders of cerebral hemodynamics and their correction in epilepsy].
Topics: Brain Ischemia; Caffeine; Cerebrovascular Circulation; Epilepsy; Humans; Papaverine; Phenobarbital | 1979 |
[An analysis of 22 years' experience with the medicinal treatment of epilepsy].
Topics: Adult; Anticonvulsants; Bromides; Caffeine; Codeine; Drug Therapy, Combination; Epilepsy; Female; Hi | 1975 |
[Changes in cerebral blood circulation and their correction in the interparoxysmal period of epilepsy].
Topics: Adolescent; Adult; Brain Ischemia; Caffeine; Cerebrovascular Circulation; Drug Therapy, Combination; | 1990 |
[Epilepsy and hypertensive crisis after intracavernous injection of metaraminol in the treatment of priapism secondary to a papaverine test].
Topics: Epilepsy; Humans; Hypertension; Male; Metaraminol; Middle Aged; Papaverine; Priapism | 1989 |