dehydroepiandrosterone has been researched along with Epilepsy in 12 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Epilepsy: A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Epilepsy is a neurological disorder characterized by the occurrence of spontaneous and recurrent seizures." | 5.62 | Response of Voltage-Gated Sodium and Calcium Channels Subtypes on Dehydroepiandrosterone Treatment in Iron-Induced Epilepsy. ( Kumar, P; Kumar, V; Mishra, M; Prakash, C; Sharma, D, 2021) |
| "Dehydroepiandrosterone (DHEA), a neuroactive androgen steroid, has antiepileptic action in iron-induced experimental epilepsy (which models post-traumatic clinical epilepsy)." | 3.79 | Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters. ( Mishra, M; Mukherjee, S; Sharma, D; Singh, R, 2013) |
| " Anthropometric measurements, staging of pubertal maturation, and clinical manifestations of hyperandrogenism were assessed, as well as measurement of serum levels of testosterone, dehydroepiandrosterone sulfate (DHEAS), sex hormone-binding globulin (SHBG), and free androgen index (FAI)." | 3.72 | Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy. ( Abd El-Basset, FZ; El Barbary, NS; El-Khayat, HA; Hakky, SM; Mohamed, MS; Nassef, NM; Tohamy, SM; Tomoum, HY; Zaky, AA, 2004) |
| "Epilepsy is a neurological disorder characterized by the occurrence of spontaneous and recurrent seizures." | 1.62 | Response of Voltage-Gated Sodium and Calcium Channels Subtypes on Dehydroepiandrosterone Treatment in Iron-Induced Epilepsy. ( Kumar, P; Kumar, V; Mishra, M; Prakash, C; Sharma, D, 2021) |
| "Treatment with carbamazepine decreased plasma OE1S levels from a mean value of 810." | 1.30 | Differential effect of carbamazepine and valproate monotherapy on plasma levels of oestrone sulphate and dehydroepiandrosterone sulphate in male epileptic patients. ( Berntsen, H; Engelsen, BA; Geisler, J; Geisler, S; Lønning, PE, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Prakash, C | 2 |
| Mishra, M | 4 |
| Kumar, P | 2 |
| Kumar, V | 2 |
| Sharma, D | 4 |
| Singh, R | 2 |
| Mukherjee, S | 1 |
| HEUSER, G | 1 |
| LING, GM | 1 |
| BUCHWALD, NA | 1 |
| El-Khayat, HA | 1 |
| Abd El-Basset, FZ | 1 |
| Tomoum, HY | 1 |
| Tohamy, SM | 1 |
| Zaky, AA | 1 |
| Mohamed, MS | 1 |
| Hakky, SM | 1 |
| El Barbary, NS | 1 |
| Nassef, NM | 1 |
| Tuveri, A | 1 |
| Paoletti, AM | 1 |
| Orrù, M | 1 |
| Melis, GB | 1 |
| Marotto, MF | 1 |
| Zedda, P | 1 |
| Marrosu, F | 1 |
| Sogliano, C | 1 |
| Marra, C | 1 |
| Biggio, G | 1 |
| Concas, A | 1 |
| Isojärvi, JI | 1 |
| Laatikainen, TJ | 1 |
| Knip, M | 1 |
| Pakarinen, AJ | 1 |
| Juntunen, KT | 1 |
| Myllylä, VV | 1 |
| Geisler, J | 1 |
| Engelsen, BA | 1 |
| Berntsen, H | 1 |
| Geisler, S | 1 |
| Lønning, PE | 1 |
| Duncan, S | 1 |
| Blacklaw, J | 1 |
| Beastall, GH | 1 |
| Brodie, MJ | 2 |
| Stephen, LJ | 1 |
| Kwan, P | 1 |
| Shapiro, D | 1 |
| Dominiczak, M | 1 |
| Christiansen, P | 1 |
| Deigaard, J | 1 |
| Lund, M | 1 |
1 trial available for dehydroepiandrosterone and Epilepsy
| Article | Year |
|---|---|
Antiepileptic drug therapy and sexual function in men with epilepsy.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Androgen-Binding Protein; Androstenedione; Anticonvul | 1999 |
11 other studies available for dehydroepiandrosterone and Epilepsy
| Article | Year |
|---|---|
Dehydroepiandrosterone alleviates oxidative stress and apoptosis in iron-induced epilepsy via activation of Nrf2/ARE signal pathway.
Topics: Animals; Antioxidants; Apoptosis; Dehydroepiandrosterone; Epilepsy; Heme Oxygenase-1; Hippocampus; I | 2019 |
Response of Voltage-Gated Sodium and Calcium Channels Subtypes on Dehydroepiandrosterone Treatment in Iron-Induced Epilepsy.
Topics: Animals; Calcium Channels; Dehydroepiandrosterone; Epilepsy; Glial Fibrillary Acidic Protein; Hippoc | 2021 |
Dehydroepiandrosterone's antiepileptic action in FeCl3-induced epileptogenesis involves upregulation of glutamate transporters.
Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Chlorides; Dehydroepiandrosterone; Elect | 2013 |
Antiepileptic action of exogenous dehydroepiandrosterone in iron-induced epilepsy in rat brain.
Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Dehydroepiandrosterone; Disease Models, Anima | 2010 |
SEDATION OR SEIZURES AS DOSE-DEPENDENT EFFECTS OF STEROIDS.
Topics: 17-Hydroxycorticosteroids; Animals; Behavior, Animal; Central Nervous System; Dehydroepiandrosterone | 1965 |
Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Dehydroepiandrosterone; Epilepsy; Female; Growth; | 2004 |
Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy.
Topics: Adult; Anticonvulsants; Body Mass Index; Dehydroepiandrosterone; Desoxycorticosterone; Electroenceph | 2008 |
Obesity and endocrine disorders in women taking valproate for epilepsy.
Topics: Adult; Body Weight; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Endocrine | 1996 |
Differential effect of carbamazepine and valproate monotherapy on plasma levels of oestrone sulphate and dehydroepiandrosterone sulphate in male epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Su | 1997 |
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Comorbidity; Dehydroepiandrosterone; Epileps | 2001 |
[Potency, fertility and sex hormones in young male epileptics].
Topics: 17-Ketosteroids; Adult; Androsterone; Anticonvulsants; Dehydroepiandrosterone; Epilepsy; Erectile Dy | 1975 |