pentylenetetrazole has been researched along with Fever in 17 studies
Pentylenetetrazole: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
pentetrazol : An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis.
Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the basic mechanism of aminophylline [theophylline-2-ethylenediamine]-induced convulsions and the effects of Brewer's yeast-induced pyrexia in mice." | 7.75 | Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K, 2009) |
| "It has been described that febrile seizures during infancy increase risk of subsequent non-febrile seizures during the adulthood." | 5.35 | Hyperthermic seizures and hyperthermia in immature rats modify the subsequent pentylenetetrazole-induced seizures. ( Gonzalez-Ramirez, M; Orozco-Suarez, SA; Rocha, L; Salgado-Ceballos, H, 2009) |
| " In this study, we investigated the basic mechanism of aminophylline [theophylline-2-ethylenediamine]-induced convulsions and the effects of Brewer's yeast-induced pyrexia in mice." | 3.75 | Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K, 2009) |
| "Inflammation is considered to be involved in epileptogenesis." | 1.91 | Inflammation as a target for the treatment of fever-associated epilepsy in zebrafish larvae. ( Liang, W; Shen, D; Shen, Y; Sui, J; Wang, J; Wu, Y; Yun, F; Zhang, Q; Zhou, J, 2023) |
| "Latency and probability of PTZ-induced seizures were shorter and higher respectively, in hyperthermia-treated animals compared to controls." | 1.40 | Cognitive performance and convulsion risk after experimentally-induced febrile-seizures in rat. ( Abdeen, Z; Al Shawaaf, F; Al-Ansari, S; Alsaffar, Y; Hassan, Z; Kamal, A; Mandeel, M; Rajab, E, 2014) |
| "It has been described that febrile seizures during infancy increase risk of subsequent non-febrile seizures during the adulthood." | 1.35 | Hyperthermic seizures and hyperthermia in immature rats modify the subsequent pentylenetetrazole-induced seizures. ( Gonzalez-Ramirez, M; Orozco-Suarez, SA; Rocha, L; Salgado-Ceballos, H, 2009) |
| "Evans-blue was used as a BBB tracer." | 1.34 | Gender difference in the influence of antioxidants on the blood-brain barrier permeability during pentylenetetrazol-induced seizures in hyperthermic rat pups. ( Akgul, S; Oztas, B; Seker, FB, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, W | 1 |
| Wang, J | 1 |
| Sui, J | 1 |
| Yun, F | 1 |
| Shen, Y | 1 |
| Zhou, J | 1 |
| Wu, Y | 1 |
| Shen, D | 1 |
| Zhang, Q | 1 |
| Menezes, FP | 1 |
| Da Silva, RS | 1 |
| Rajab, E | 1 |
| Abdeen, Z | 1 |
| Hassan, Z | 1 |
| Alsaffar, Y | 1 |
| Mandeel, M | 1 |
| Al Shawaaf, F | 1 |
| Al-Ansari, S | 1 |
| Kamal, A | 1 |
| Dai, YJ | 1 |
| Xu, ZH | 1 |
| Feng, B | 1 |
| Xu, CL | 1 |
| Zhao, HW | 1 |
| Wu, DC | 1 |
| Hu, WW | 1 |
| Chen, Z | 1 |
| Gonzalez-Ramirez, M | 1 |
| Salgado-Ceballos, H | 1 |
| Orozco-Suarez, SA | 1 |
| Rocha, L | 1 |
| Ngo Bum, E | 1 |
| Taiwe, GS | 1 |
| Moto, FC | 1 |
| Ngoupaye, GT | 1 |
| Nkantchoua, GC | 1 |
| Pelanken, MM | 1 |
| Rakotonirina, SV | 1 |
| Rakotonirina, A | 1 |
| Ochi, R | 1 |
| Suemaru, K | 1 |
| Kawasaki, H | 1 |
| Araki, H | 1 |
| Hikichi, H | 1 |
| Murai, T | 1 |
| Okuda, S | 1 |
| Maehara, S | 1 |
| Satow, A | 1 |
| Ise, S | 1 |
| Nishino, M | 1 |
| Suzuki, G | 1 |
| Takehana, H | 1 |
| Hata, M | 1 |
| Ohta, H | 1 |
| FUNCKE, AB | 1 |
| MULDER, D | 1 |
| DEJONGE, MC | 1 |
| TERSTEEGE, HM | 1 |
| HARMS, AF | 1 |
| NAUTA, WT | 1 |
| DONNER, R | 1 |
| RUEMKE, CL | 1 |
| Heida, JG | 1 |
| Boissé, L | 1 |
| Pittman, QJ | 1 |
| Oztas, B | 1 |
| Akgul, S | 1 |
| Seker, FB | 1 |
| van Gassen, KL | 1 |
| Hessel, EV | 1 |
| Ramakers, GM | 1 |
| Notenboom, RG | 1 |
| Wolterink-Donselaar, IG | 1 |
| Brakkee, JH | 1 |
| Godschalk, TC | 1 |
| Qiao, X | 1 |
| Spruijt, BM | 1 |
| van Nieuwenhuizen, O | 1 |
| de Graan, PN | 1 |
| Malinka, W | 1 |
| Tatarczyńska, E | 1 |
| Pattij, T | 1 |
| Groenink, L | 1 |
| Oosting, RS | 1 |
| van der Gugten, J | 1 |
| Maes, RA | 1 |
| Olivier, B | 1 |
| Tubaro, E | 1 |
| Banci, F | 1 |
| Suchowsky, GK | 1 |
| Pegrassi, L | 1 |
| Fermum, R | 1 |
17 other studies available for pentylenetetrazole and Fever
| Article | Year |
|---|---|
Inflammation as a target for the treatment of fever-associated epilepsy in zebrafish larvae.
Topics: Animals; Disease Models, Animal; Epilepsy; Fever; Humans; Inflammation; Interleukin-1beta; Interleuk | 2023 |
The influence of temperature on adult zebrafish sensitivity to pentylenetetrazole.
Topics: Animals; Anticonvulsants; Body Weight; Convulsants; Dizocilpine Maleate; Female; Fever; Male; Models | 2017 |
Cognitive performance and convulsion risk after experimentally-induced febrile-seizures in rat.
Topics: Analysis of Variance; Animals; Cognition Disorders; Convulsants; Disease Models, Animal; Dose-Respon | 2014 |
Gender difference in acquired seizure susceptibility in adult rats after early complex febrile seizures.
Topics: Animals; Convulsants; Disease Models, Animal; Disease Susceptibility; Electroshock; Female; Fever; M | 2014 |
Hyperthermic seizures and hyperthermia in immature rats modify the subsequent pentylenetetrazole-induced seizures.
Topics: Animals; Animals, Newborn; Convulsants; Disease Models, Animal; Female; Fever; Male; Pentylenetetraz | 2009 |
Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Cameroon; Convulsants; Diazepam; Dose-Respon | 2009 |
Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Apnea; Bronchodilator Agents; Child; Convulsants; Diazepam; | 2009 |
Effects of a novel metabotropic glutamate receptor 7 negative allosteric modulator, 6-(4-methoxyphenyl)-5-methyl-3-pyridin-4-ylisoxazonolo[4,5-c]pyridin-4(5H)-one (MMPIP), on the central nervous system in rodents.
Topics: Allosteric Regulation; Animals; Behavior, Animal; Central Nervous System; Cognition; Electric Counte | 2010 |
INVESTIGATION OF 3-(10,11-DIHYDRO-5H-DIBENZO (A,D) CYCLOHEPTEN-5-YLOXY) TROPANE CITRATE (DIBENZHEPTROPINE CITRATE, BRONTINE). I. PHARMACOLOGICAL PROPERTIES. II. TOXICOLOGICAL PROPERTIES.
Topics: Acetylcholine; Albumins; Animals; Asthma; Atropine; Bronchi; Citric Acid; Cyproheptadine; Diphenhydr | 1964 |
Lipopolysaccharide-induced febrile convulsions in the rat: short-term sequelae.
Topics: Animals; Animals, Newborn; Body Temperature; Brain; Cell Death; Disease Models, Animal; Female; Feve | 2004 |
Gender difference in the influence of antioxidants on the blood-brain barrier permeability during pentylenetetrazol-induced seizures in hyperthermic rat pups.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Convulsants; Female; Fever; Male; Neuroprotective Agents | 2007 |
Characterization of febrile seizures and febrile seizure susceptibility in mouse inbred strains.
Topics: Animals; Behavior, Animal; Convulsants; Electrophysiology; Fever; Genetic Predisposition to Disease; | 2008 |
Synthesis and pharmacological properties of N-(4-substituted-1-piperazinylalkyl)-1-butyl-2,5-dimethylpyrrole-3,4- dicarboxyimide derivatives.
Topics: Animals; Anticonvulsants; Apomorphine; Central Nervous System Agents; Chemical Phenomena; Chemistry, | 1993 |
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Diazepam; Ethanol; Fever; Flumazenil; GABA Antagonists; Hy | 2002 |
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101).
Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageena | 1970 |
The pharmacology of 4H-3-methylcarboxyamide-1,3-benzoxazine-2-one (F.I. 6654), a compound acting on the central nervous system.
Topics: Anesthesia; Animals; Atropine; Barbiturates; Behavior, Animal; Cats; Central Nervous System; Depress | 1969 |
[On the pharmacological action spectrum of some new hydrazine derivatives].
Topics: Animals; Anura; Blood Pressure; Body Temperature; Cats; Drug Synergism; Electroshock; Epilepsy; Feve | 1966 |