Page last updated: 2024-10-25

diazepam and Fever

diazepam has been researched along with Fever in 81 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"We have observed two cases of chlorpromazine-induced neuroleptic malignant syndrome (NMS); both were transiently responsive to intravenous diazepam challenge, but not to blind placebo or amyobarbitol."9.05Chlorpromazine-induced neuroleptic malignant syndrome and its response to diazepam. ( Lew, TY; Tollefson, G, 1983)
"This study was undertaken to evaluate the efficacy, safety, and economic impact of diazepam suppositories with as-needed acetaminophen in comparison with as-needed acetaminophen alone for prevention of seizure recurrence during the same fever episode in suspected pediatric simple febrile seizures (SFS)."8.12Efficacy, safety, and economic impact of diazepam suppositories with as-needed acetaminophen for prevention of seizure recurrence during the same fever episode in children with suspected simple febrile seizures. ( Fujita, S; Hataya, H; Kishibe, S; Miyama, S; Morikawa, EK; Morikawa, Y; Narita, K; Sammori, H; Suzuki, S; Takehira, K; Tanaka, M; Tsukamoto, J; Wang, Q; Yano, M, 2022)
" In this study, we investigated the basic mechanism of aminophylline [theophylline-2-ethylenediamine]-induced convulsions and the effects of Brewer's yeast-induced pyrexia in mice."7.75Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K, 2009)
" We studied the effects of a calcium antagonist diltiazem, as well as diazepam and phenytoin on hyperthermia induced seizures in unrestrained 15 day-old rats."7.68Effects of diltiazem on hyperthermia induced seizures in the rat pup. ( Carrillo, E; Laorden, ML; Miralles, FS; Puig, MM, 1990)
" Adverse events (AEs) and usability assessments were recorded after the first dose, then every 3 months."6.94Safety and tolerability associated with chronic intermittent use of diazepam buccal film in adult, adolescent, and pediatric patients with epilepsy. ( Buan, C; Gelfand, MA; Heller, AH; Seinfeld, S; Slatko, G, 2020)
"Pre-treatment with diazepam, 10 and 20mg/kg, and chlormethiazole, 50 and 100mg/kg, attenuated the development of hyperthermia."5.32Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2003)
"Cocaine-related rhabdomyolysis has a high mortality."5.29Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome? ( Daras, M; Kakkouras, L; Koppel, BS; Tuchman, AJ, 1995)
" Diazepam, administered only during episodes of fever, may be a safe, effective agent to prevent the recurrence of febrile seizures."5.07A controlled trial of diazepam administered during febrile illnesses to prevent recurrence of febrile seizures. ( Colton, T; Gardella, NB; Gilbert, PL; Kaye, EM; Labazzo, J; Rosman, NP; Van Bennekom, C; Winter, MR, 1993)
"We have observed two cases of chlorpromazine-induced neuroleptic malignant syndrome (NMS); both were transiently responsive to intravenous diazepam challenge, but not to blind placebo or amyobarbitol."5.05Chlorpromazine-induced neuroleptic malignant syndrome and its response to diazepam. ( Lew, TY; Tollefson, G, 1983)
"This study was undertaken to evaluate the efficacy, safety, and economic impact of diazepam suppositories with as-needed acetaminophen in comparison with as-needed acetaminophen alone for prevention of seizure recurrence during the same fever episode in suspected pediatric simple febrile seizures (SFS)."4.12Efficacy, safety, and economic impact of diazepam suppositories with as-needed acetaminophen for prevention of seizure recurrence during the same fever episode in children with suspected simple febrile seizures. ( Fujita, S; Hataya, H; Kishibe, S; Miyama, S; Morikawa, EK; Morikawa, Y; Narita, K; Sammori, H; Suzuki, S; Takehira, K; Tanaka, M; Tsukamoto, J; Wang, Q; Yano, M, 2022)
" Administration of diazepam, insertion of an airway and pyrexia perfectly predicted transport to hospital, tachycardia had a modest association, but other variables were only weak predictors of transport to hospital."3.88Pre-hospital ambulance care of patients following a suspected seizure: A cross sectional study. ( Asghar, ZB; Dickson, JM; Siriwardena, AN, 2018)
" In this study, we investigated the basic mechanism of aminophylline [theophylline-2-ethylenediamine]-induced convulsions and the effects of Brewer's yeast-induced pyrexia in mice."3.75Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice. ( Araki, H; Kawasaki, H; Ochi, R; Suemaru, K, 2009)
" We studied the effects of a calcium antagonist diltiazem, as well as diazepam and phenytoin on hyperthermia induced seizures in unrestrained 15 day-old rats."3.68Effects of diltiazem on hyperthermia induced seizures in the rat pup. ( Carrillo, E; Laorden, ML; Miralles, FS; Puig, MM, 1990)
" Adverse events (AEs) and usability assessments were recorded after the first dose, then every 3 months."2.94Safety and tolerability associated with chronic intermittent use of diazepam buccal film in adult, adolescent, and pediatric patients with epilepsy. ( Buan, C; Gelfand, MA; Heller, AH; Seinfeld, S; Slatko, G, 2020)
"We studied 203 children with febrile seizures from December 2004 through March 2006."2.74Efficacy of a diazepam suppository at preventing febrile seizure recurrence during a single febrile illness. ( Hirabayashi, Y; Kando, N; Kawabe, S; Kondo, T; Magota, M; Natsume, J; Negoro, T; Okumura, A; Watanabe, K; Yamaguchi, H, 2009)
"The risk of recurrences was significantly lower in children receiving continuous phenobarbital therapy than placebo (odds ratio 0."2.40A meta-analytic review of the preventive treatment of recurrences of febrile seizures. ( Rantala, H; Tarkka, R; Uhari, M, 1997)
"Febrile seizures are common in children."2.37The child with febrile seizures. ( Wright, SW, 1987)
"Febrile seizures are a common problem."2.37Febrile seizures: emergency department diagnosis and treatment. ( Ater, SB; Bettis, DB, 1985)
"None presented afebrile seizures."1.72Non-convulsive febrile status epilepticus mimicking a postictal state after a febrile seizure: an ictal electroclinical and evolutive study. ( Bernardina, BD; Cantalupo, G; Darra, F; Fiorini, E; Fontana, E; Lo Barco, T; Meneghello, L; Proietti, J, 2022)
"Diazepam (2mg/kg) was used as positive control."1.46Anxiolytic properties of N-acetylcysteine in mice. ( Benvenutti, R; Elisabetsky, E; Gama, CS; Giongo, F; Herrmann, AP; Noetzold, G; Piato, AL; Santos, P, 2017)
"Carbamazepine was significantly more efficacious than diazepam suppositories in the aFc group (odds ratio = 49."1.46Clinical Epidemiology and Treatment of Febrile and Afebrile Convulsions With Mild Gastroenteritis: A Multicenter Study. ( Higuchi, Y; Horibe, K; Ichimi, R; Iguchi, K; Kamimaki, I; Koga, H; Komiyama, O; Kubo, T; Mitsuhashi, T; Miyagawa, S; Nakamura, N; Saito, A; Shukuya, A; Takayanagi, T; Tanaka, S; Uchida, Y; Watanabe, K; Yamamoto, S; Yamashita, H; Yokota, I, 2017)
"Pre-treatment with diazepam, 10 and 20mg/kg, and chlormethiazole, 50 and 100mg/kg, attenuated the development of hyperthermia."1.32Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2003)
"Naloxone alone was ineffective."1.30Naloxone blocks anxiolytic-like effects of benzodiazepines in Swiss but not in Balb/c mice. ( Agmo, A; Belzung, C, 1997)
"Cocaine-related rhabdomyolysis has a high mortality."1.29Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome? ( Daras, M; Kakkouras, L; Koppel, BS; Tuchman, AJ, 1995)
" Acetaminophen and diazepam seemed to be well absorbed from the rectal suppositories, the maximal plasma concentration of diazepam after a rectal dose of 0."1.26Antipyretic effect and plasma concentrations of rectal acetaminophen and diazepam in children. ( Kangas, L; Keinänen-Kiukaanniemi, S; Luoma, P; Saukkonen, AL; Similä, S, 1979)
"Simple febrile convulsions occur in otherwise normal children, aged six months to five years, with extracranial infection."1.26Simple febrile convulsions. ( Mendelsohn, J; Rosen, P; Tomlanovich, MC, 1976)
"The adverse effects in a series of 50 lumbar myelographies with Amipaque were compared with those in a corresponding series, examined with Dimer-X."1.26Adverse effects of lumbar myelography with amipaque and dimer-X. ( Irstam, L; Selldén, U, 1976)
"The characteristics, circumstances, and treatment of 450 pyrexial reactions occurring in 468 patient-months over a period of two and a half years, using a warm single-pass Kiil system, were studied."1.25Pyrexial reactions during haemodialysis. ( Robinson, PJ; Rosen, SM, 1971)

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-199039 (48.15)18.7374
1990's13 (16.05)18.2507
2000's13 (16.05)29.6817
2010's13 (16.05)24.3611
2020's3 (3.70)2.80

Authors

AuthorsStudies
Tripathi, P1
Tripathi, AC1
Chawla, V1
Saraf, SK1
Proietti, J1
Fiorini, E1
Meneghello, L1
Cantalupo, G1
Fontana, E1
Lo Barco, T1
Bernardina, BD1
Darra, F1
Tanaka, M1
Wang, Q1
Morikawa, Y1
Tsukamoto, J1
Sammori, H1
Takehira, K1
Yano, M1
Miyama, S1
Fujita, S1
Narita, K1
Kishibe, S1
Morikawa, EK1
Suzuki, S1
Hataya, H1
Seinfeld, S1
Gelfand, MA1
Heller, AH1
Buan, C1
Slatko, G1
Carter, C1
Viveash, S1
Dickson, JM1
Asghar, ZB1
Siriwardena, AN1
Benelli, E1
Massaro, M1
Norbedo, S1
Carbone, M1
Barbi, E1
Ventura, A1
Bamford, A1
Crowe, BH1
Hacohen, Y1
Lin, JP1
Clarke, A1
Tudor-Williams, G1
Sancho-Shimizu, V1
Vincent, A1
Lim, M1
Pullaperuma, SP1
Zhang, P1
Austin, E1
Thompson, M1
Lin, S1
Santos, P1
Herrmann, AP1
Benvenutti, R1
Noetzold, G1
Giongo, F1
Gama, CS1
Piato, AL1
Elisabetsky, E1
Miyamoto, T1
Funakami, Y1
Kawashita, E1
Nomura, A1
Sugimoto, N1
Saeki, H1
Tsubota, M1
Ichida, S1
Kawabata, A1
Higuchi, Y1
Kubo, T1
Mitsuhashi, T1
Nakamura, N1
Yokota, I1
Komiyama, O1
Kamimaki, I1
Yamamoto, S1
Uchida, Y1
Watanabe, K2
Yamashita, H1
Tanaka, S1
Iguchi, K1
Ichimi, R1
Miyagawa, S1
Takayanagi, T1
Koga, H1
Shukuya, A1
Saito, A1
Horibe, K1
Bespalov, AY1
van Gaalen, MM1
Sukhotina, IA1
Wicke, K1
Mezler, M1
Schoemaker, H1
Gross, G1
Hirabayashi, Y2
Okumura, A2
Kondo, T1
Magota, M1
Kawabe, S1
Kando, N1
Yamaguchi, H1
Natsume, J2
Negoro, T1
Vinkers, CH2
Groenink, L8
van Bogaert, MJ2
Westphal, KG2
Kalkman, CJ1
van Oorschot, R4
Oosting, RS4
Olivier, B10
Korte, SM2
Ngo Bum, E1
Taiwe, GS1
Moto, FC1
Ngoupaye, GT1
Nkantchoua, GC1
Pelanken, MM1
Rakotonirina, SV1
Rakotonirina, A1
Ochi, R1
Suemaru, K1
Kawasaki, H1
Araki, H1
Sert, A1
Yazar, A1
Odabas, D1
Wierońska, JM1
Stachowicz, K1
Pałucha-Poniewiera, A1
Acher, F1
Brański, P1
Pilc, A1
Nisijima, K1
Shioda, K1
Yoshino, T1
Takano, K1
Kato, S1
Chen, SW1
Min, L1
Li, WJ1
Kong, WX1
Li, JF1
Zhang, YJ1
van der Gugten, J5
Van Bogaert, M1
Oosting, R1
Toth, M1
Procopis, PG1
Lew, TY1
Tollefson, G1
Ogunmekan, AO1
Daras, M1
Kakkouras, L1
Tuchman, AJ1
Koppel, BS1
Rosman, NP1
Colton, T1
Labazzo, J1
Gilbert, PL1
Gardella, NB1
Kaye, EM1
Van Bennekom, C1
Winter, MR1
Compaan, J1
Zethof, T1
van der Heyden, J1
Zethof, TJ3
van der Heyden, JA2
Ali, SF1
Newport, GD1
Slikker, W1
Belzung, C1
Agmo, A1
Rantala, H1
Tarkka, R1
Uhari, M1
Pattij, T3
Hijzen, TH1
Maes, RA2
Hen, R1
Tabarki, B1
Yacoub, M1
Selmi, H1
Oubich, F1
Barsaoui, S1
Essoussi, AS1
Bouwknecht, JA1
Leahy, C1
Keinänen-Kiukaanniemi, S1
Similä, S1
Luoma, P1
Kangas, L1
Saukkonen, AL1
Sedgwick, CJ1
King, J1
Barnett, PS1
Kew, MC1
Lawson, J1
Wallace, SJ1
Khalid, MS1
Schulz, H1
Snow, AE1
Horita, A1
Johnsen, SD1
Silbermann, RM1
Boer, F1
Posner, JB1
Buttitta, P1
Pasta, G1
Macaione, D1
Tomlanovich, MC1
Rosen, P1
Mendelsohn, J1
Irstam, L1
Selldén, U1
Luna Lagares, S1
Lopez Alcaide, I1
Cano Franco, J1
Andres Martin, A1
Kashiwagi, H1
Lecci, A1
Borsini, F1
Mancinelli, A1
D'Aranno, V1
Stasi, MA1
Volterra, G1
Meli, A1
Laorden, ML1
Carrillo, E1
Miralles, FS1
Puig, MM1
Banet, M1
Wright, SW1
van Miert, AS1
van Duin, CT1
Anika, SM1
Brown, DC1
Savage, JM1
Bettis, DB1
Ater, SB1
Ouellette, EM1
Friedlander, WJ1
Smith, MJ1
Kendall, BE1
Tomlinson, S1
Lichtman, AS1
Brenner, P1
Mishell, DR1
Cavazzuti, GB1
Murray, JD1
Fleming, P1
Weber, J1
Hsuen, J1
Bannatyne, R1
Anglin, C1
Hohenauer, L1
Hoch, FL1
Hogan, FP1
Langevin, P1
Wilson, J1
Langslet, A1
Brett, EM1
Gruhl, D1
Thorn, I1
Vittadini, G1
Canubi, A1
Robinson, PJ1
Rosen, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy of A Single Dose Clonazepam Compared With the Intermittent Diazepam to Prevent Recurrent Febrile Seizures in Queen Sirikit National Institute of Child Health[NCT04364321]74 participants (Anticipated)Interventional2020-05-13Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for diazepam and Fever

ArticleYear
A meta-analytic review of the preventive treatment of recurrences of febrile seizures.
    The Journal of pediatrics, 1997, Volume: 131, Issue:6

    Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Huma

1997
The child with febrile seizures.
    American family physician, 1987, Volume: 36, Issue:5

    Topics: Child, Preschool; Diagnosis, Differential; Diazepam; Fever; Humans; Infant; Phenobarbital; Prognosis

1987
Febrile seizures: emergency department diagnosis and treatment.
    The Journal of emergency medicine, 1985, Volume: 2, Issue:5

    Topics: Blood Cell Count; Blood Glucose; Child, Preschool; Counseling; Diagnosis, Differential; Diazepam; Dr

1985
The child who convulses with fever.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:2

    Topics: Age Factors; Analgesics; Brain Injuries; Central Nervous System Diseases; Child; Child Behavior; Chi

1974
Epilepsy.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Adolescent; Animals; Barbiturates; Brain Neoplasms; Cell Membrane Permeability; Central Nervous Syst

1968
The continuing problem of purulent meningitis in infants and children.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:4

    Topics: Bacterial Vaccines; Bicarbonates; Brain Edema; Diagnosis, Differential; Diazepam; Digoxin; Fever; Ga

1974

Trials

4 trials available for diazepam and Fever

ArticleYear
Safety and tolerability associated with chronic intermittent use of diazepam buccal film in adult, adolescent, and pediatric patients with epilepsy.
    Epilepsia, 2020, Volume: 61, Issue:11

    Topics: Administration, Buccal; Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Diazepam;

2020
Efficacy of a diazepam suppository at preventing febrile seizure recurrence during a single febrile illness.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Age Factors; Anticonvulsants; Child, Preschool; Diagnosis, Differential; Diagnostic Errors; Diazepam

2009
Chlorpromazine-induced neuroleptic malignant syndrome and its response to diazepam.
    Biological psychiatry, 1983, Volume: 18, Issue:12

    Topics: Brain; Chlorpromazine; Diazepam; Dopamine; Dyskinesia, Drug-Induced; Dystonia; Female; Fever; gamma-

1983
A controlled trial of diazepam administered during febrile illnesses to prevent recurrence of febrile seizures.
    The New England journal of medicine, 1993, Jul-08, Volume: 329, Issue:2

    Topics: Administration, Oral; Child, Preschool; Diazepam; Double-Blind Method; Drug Administration Schedule;

1993

Other Studies

71 other studies available for diazepam and Fever

ArticleYear
Syntheses, characterization and evaluation of novel 2,6-diarylpiperidin-4-ones as potential analgesic-antipyretic agents.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Acetic Acid; Analgesics; Animals; Antipyretics; Body Temperature; Dose-Response Relationship, Drug;

2014
Non-convulsive febrile status epilepticus mimicking a postictal state after a febrile seizure: an ictal electroclinical and evolutive study.
    Epileptic disorders : international epilepsy journal with videotape, 2022, Apr-01, Volume: 24, Issue:2

    Topics: Child; Cyanosis; Diazepam; Electroencephalography; Fever; Humans; Infant; Seizures, Febrile; Status

2022
Efficacy, safety, and economic impact of diazepam suppositories with as-needed acetaminophen for prevention of seizure recurrence during the same fever episode in children with suspected simple febrile seizures.
    Epilepsia, 2022, Volume: 63, Issue:7

    Topics: Acetaminophen; Child; Diazepam; Fever; Humans; Infant; Prospective Studies; Recurrence; Seizures, Fe

2022
Nursing a critically ill tetanus patient in an intensive care unit in Zambia.
    British journal of nursing (Mark Allen Publishing), 2017, May-11, Volume: 26, Issue:9

    Topics: Analgesics, Opioid; Anti-Infective Agents; Anticonvulsants; Back Pain; Critical Care Nursing; Critic

2017
Pre-hospital ambulance care of patients following a suspected seizure: A cross sectional study.
    Seizure, 2018, Volume: 57

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Airway Management; Ambulances; Anticonvulsants; Cross-Se

2018
An unusual cause of torticollis.
    The Journal of pediatrics, 2013, Volume: 163, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Atlanto-Axial Joint; Child, Preschool; Diazepam; Female; Fe

2013
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
    Journal of the Pediatric Infectious Diseases Society, 2015, Volume: 4, Issue:2

    Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonid

2015
Challenges in a large mixed drug overdose patient.
    BMJ case reports, 2016, Jun-22, Volume: 2016

    Topics: Adult; Anticonvulsants; Body Temperature Regulation; Critical Care; Delirium; Diazepam; Drug Overdos

2016
Anxiolytic properties of N-acetylcysteine in mice.
    Behavioural brain research, 2017, 01-15, Volume: 317

    Topics: Acetylcysteine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Body Temperature; Dark

2017
Repeated Cold Stress Enhances the Acute Restraint Stress-Induced Hyperthermia in Mice.
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:1

    Topics: Adipose Tissue, Brown; Adrenergic beta-3 Receptor Antagonists; Animals; Anti-Anxiety Agents; Cold Te

2017
Clinical Epidemiology and Treatment of Febrile and Afebrile Convulsions With Mild Gastroenteritis: A Multicenter Study.
    Pediatric neurology, 2017, Volume: 67

    Topics: Anticonvulsants; Carbamazepine; Diazepam; Female; Fever; Gastroenteritis; Humans; Infant; Linear Mod

2017
Behavioral characterization of the mGlu group II/III receptor antagonist, LY-341495, in animal models of anxiety and depression.
    European journal of pharmacology, 2008, Sep-11, Volume: 592, Issue:1-3

    Topics: Amino Acids; Amphetamine; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; An

2008
Stress-induced hyperthermia and infection-induced fever: two of a kind?
    Physiology & behavior, 2009, Aug-04, Volume: 98, Issue:1-2

    Topics: Animals; Aspirin; Diazepam; Dose-Response Relationship, Drug; Electrodes, Implanted; Fever; GABA Ago

2009
Anticonvulsant, anxiolytic, and sedative properties of the roots of Nauclea latifolia Smith in mice.
    Epilepsy & behavior : E&B, 2009, Volume: 15, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Cameroon; Convulsants; Diazepam; Dose-Respon

2009
Effect of Brewer's yeast-induced pyrexia on aminophylline-elicited convulsions in mice.
    Acta medica Okayama, 2009, Volume: 63, Issue:5

    Topics: Aminophylline; Animals; Anticonvulsants; Apnea; Bronchodilator Agents; Child; Convulsants; Diazepam;

2009
5-HT1A receptor blockade reverses GABA(A) receptor alpha3 subunit-mediated anxiolytic effects on stress-induced hyperthermia.
    Psychopharmacology, 2010, Volume: 211, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Body Temperature; Diazepam; Dose-Response Relationship, Drug; Fever; G

2010
Efficacy of a diazepam at preventing febrile seizure recurrence after febrile illness.
    Brain & development, 2010, Volume: 32, Issue:10

    Topics: Anticonvulsants; Child; Diazepam; Fever; Humans; Secondary Prevention; Seizures, Febrile; Suppositor

2010
Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems.
    Neuropharmacology, 2010, Volume: 59, Issue:7-8

    Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Antidepressive Agents; Diazepam; Fever; Flumazenil; GA

2010
Reply comments to 'Efficacy of a diazepam at preventing febrile seizure recurrence after febrile illness'.
    Brain & development, 2011, Volume: 33, Issue:1

    Topics: Anticonvulsants; Clinical Trials as Topic; Diazepam; Fever; Secondary Prevention; Seizures, Febrile;

2011
Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome.
    Neurochemistry international, 2003, Volume: 43, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Brain; Chlormethiazole; Clorgyline; Diazepam; Diseas

2003
The effects of angelica essential oil in three murine tests of anxiety.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:2

    Topics: Angelica sinensis; Animals; Anti-Anxiety Agents; Anxiety; Darkness; Diazepam; Disease Models, Animal

2004
Mouse strain differences in autonomic responses to stress.
    Genes, brain, and behavior, 2006, Volume: 5, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Autonomic Nervous System; Autonomic Nervous System

2006
Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: modulation by serotonergic and GABAA-ergic drugs.
    European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3

    Topics: Animals; Body Temperature; Body Temperature Regulation; Buspirone; Diazepam; Fever; Flumazenil; Fluo

2006
Febrile convulsions.
    Australian family physician, 1983, Volume: 12, Issue:9

    Topics: Anticonvulsants; Child, Preschool; Diazepam; Female; Fever; Humans; Infant; Male; Phenobarbital; Rec

1983
Some practical hints and management of convulsions occurring in infancy and children.
    Tropical doctor, 1981, Volume: 11, Issue:1

    Topics: Anticonvulsants; Child, Preschool; Diazepam; Epilepsy; Fever; Humans; Infant; Infant, Newborn; Seizu

1981
Febrile seizures: long-term management of children with fever-associated seizures. Summary of an NIH consensus statement.
    British medical journal, 1980, Jul-26, Volume: 281, Issue:6235

    Topics: Child, Preschool; Diazepam; Epilepsy; Fever; Humans; Infant; Phenobarbital; Risk; Seizures; Seizures

1980
Rhabdomyolysis and hyperthermia after cocaine abuse: a variant of the neuroleptic malignant syndrome?
    Acta neurologica Scandinavica, 1995, Volume: 92, Issue:2

    Topics: Adult; Antipsychotic Agents; Brain; Cell Death; Cocaine; Diagnosis, Differential; Diazepam; Female;

1995
Stress-induced hyperthermia in mice. Pharmacological and endocrinological aspects.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 771

    Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Corticosterone; Diazepam; Fever; Hypnotics and

1995
Neuroendocrine effects of diazepam and flesinoxan in the stress-induced hyperthermia test in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 54, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Body Temperature; Corticosterone; Diazepam; Fev

1996
Methamphetamine-induced dopaminergic toxicity in mice. Role of environmental temperature and pharmacological agents.
    Annals of the New York Academy of Sciences, 1996, Oct-31, Volume: 801

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Diazepam; Dizocilpine Maleate; Dopamine; F

1996
Naloxone blocks anxiolytic-like effects of benzodiazepines in Swiss but not in Balb/c mice.
    Psychopharmacology, 1997, Volume: 132, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Exploratory Behavior; Fever; Male; Mice; M

1997
Stress-induced hyperthermia in singly housed mice.
    Physiology & behavior, 1997, Volume: 62, Issue:3

    Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Body Temperature; Diazepam; Fever; Male; Mice; Models,

1997
Stress-induced hyperthermia in the 5-HT(1A) receptor knockout mouse is normal.
    Biological psychiatry, 2001, Apr-01, Volume: 49, Issue:7

    Topics: Animals; Corticosterone; Diazepam; Fever; GABA Modulators; Male; Mice; Mice, Knockout; Multivariate

2001
Infantile status epilepticus in Tunisia. Clinical, etiological and prognostic aspects.
    Seizure, 2001, Volume: 10, Issue:5

    Topics: Anticonvulsants; Central Nervous System Infections; Chi-Square Distribution; Child, Preschool; Clona

2001
GABAA-benzodiazepine receptor complex ligands and stress-induced hyperthermia in singly housed mice.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:1-2

    Topics: Animals; Body Temperature; Diazepam; Dose-Response Relationship, Drug; Fever; GABA-A Receptor Agonis

2002
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.
    European journal of pharmacology, 2002, Jun-28, Volume: 447, Issue:1

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Diazepam; Ethanol; Fever; Flumazenil; GABA Antagonists; Hy

2002
Antipyretic effect and plasma concentrations of rectal acetaminophen and diazepam in children.
    Epilepsia, 1979, Volume: 20, Issue:6

    Topics: Acetaminophen; Body Temperature; Child; Child, Preschool; Diazepam; Drug Therapy, Combination; Fever

1979
Field anesthesia in stressed animals.
    Modern veterinary practice, 1979, Volume: 60, Issue:7

    Topics: Acepromazine; Acidosis; Anesthesia; Animals; Animals, Zoo; Artiodactyla; Diazepam; Etorphine; Fever;

1979
Drug-induced hyperpyrexia. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Aug-04, Volume: 56, Issue:5

    Topics: Bromazepam; Diazepam; Female; Fever; Heat Exhaustion; Humans; Middle Aged; Monoamine Oxidase Inhibit

1979
Current views on the management of eclampsia.
    Clinics in obstetrics and gynaecology, 1977, Volume: 4, Issue:3

    Topics: Abruptio Placentae; Acid-Base Equilibrium; Acute Kidney Injury; Diazepam; Eclampsia; Female; Fever;

1977
Problems of childhood. Febrile fits.
    British medical journal, 1976, Feb-07, Volume: 1, Issue:6005

    Topics: Age Factors; Child, Preschool; Diazepam; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Infant; Male

1976
The treatment and management of emergency status epilepticus.
    Epilepsia, 1976, Volume: 17, Issue:1

    Topics: Age Factors; Brain Edema; Child; Chlormethiazole; Diazepam; Emergencies; Epilepsy, Absence; Epilepsy

1976
Preliminary studies on the effect of electric foot shock stress on apomorphine induced hyperthermia.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Animals; Apomorphine; Behavior, Animal; Diazepam; Electroshock; Fever; Haloperidol; Male; Rabbits; S

1977
Some important pitfalls in the diagnosis and treatment of bacterial meningitis in children.
    Clinical pediatrics, 1975, Volume: 14, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Infections; Barbiturates; Cerebral Ventriculography; Cerebrospinal

1975
[A life-threatening psychosis].
    Nederlands tijdschrift voor geneeskunde, 1975, May-03, Volume: 119, Issue:18

    Topics: Acute Disease; Delirium; Dexamethasone; Diazepam; Drug Interactions; Drug-Related Side Effects and A

1975
The comatose patient.
    JAMA, 1975, Sep-22, Volume: 233, Issue:12

    Topics: Coma; Dexamethasone; Diazepam; Emergencies; Fever; Glucose; Humans; Hypothermia; Intracranial Pressu

1975
[Febrile convulsions in childhood. Clinico-statistical study].
    La Pediatria, 1975, Jun-30, Volume: 83, Issue:2

    Topics: Age Factors; Analgesics; Anti-Bacterial Agents; Barbiturates; Child; Child, Preschool; Diazepam; Fev

1975
Simple febrile convulsions.
    JACEP, 1976, Volume: 5, Issue:5

    Topics: Cerebrospinal Fluid; Child, Preschool; Diazepam; Emergency Service, Hospital; Fever; Humans; Infant;

1976
Adverse effects of lumbar myelography with amipaque and dimer-X.
    Acta radiologica: diagnosis, 1976, Volume: 17, Issue:2

    Topics: Adult; Aged; Brain; Diazepam; Drug Evaluation; Electroencephalography; Female; Fever; Headache; Huma

1976
[Efficacy of a diazepam solution for rectal administration in the control of febrile convulsions].
    Anales espanoles de pediatria, 1992, Volume: 37, Issue:6

    Topics: Administration, Rectal; Child; Diazepam; Fever; Humans; Seizures; Solutions

1992
[Diagnosis and therapy of emergency patients with fever].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1991, Dec-10, Volume: 80, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cryotherapy; Diazepam; Dopamine; Fever; Humans

1991
Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Body

1990
Effects of diltiazem on hyperthermia induced seizures in the rat pup.
    General pharmacology, 1990, Volume: 21, Issue:3

    Topics: Animals; Behavior, Animal; Body Temperature; Diazepam; Diltiazem; Fever; Phenytoin; Rats; Rats, Inbr

1990
A feverlike response inhibits expression of delayed-type hypersensitivity in rats.
    The American journal of physiology, 1990, Volume: 259, Issue:1 Pt 2

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Animals; Body Temperature; Catecholamines; Diazepam; Fever;

1990
Anorexia during febrile conditions in dwarf goats. The effect of diazepam, flurbiprofen and naloxone.
    The veterinary quarterly, 1986, Volume: 8, Issue:4

    Topics: Animals; Anorexia; Diazepam; Drug Therapy, Combination; Eating; Ehrlichia; Endotoxins; Escherichia c

1986
Therapeutic aspirin overdose in a three-year-old boy.
    The Ulster medical journal, 1987, Volume: 56, Issue:1

    Topics: Aspirin; Child, Preschool; Diazepam; Fever; Humans; Male; Seizures

1987
Adverse general reactions to high doses of methylglucamine-based contrast media.
    The British journal of radiology, 1974, Volume: 47, Issue:561

    Topics: Adipates; Adult; Age Factors; Alkaline Phosphatase; Amino Sugars; Calcium; Chlorpheniramine; Contras

1974
Intrauterine administration of prostaglandin F2alpha as an outpatient procedure for termination of early pregnancy.
    Contraception, 1974, Volume: 9, Issue:4

    Topics: Abortion, Induced; Abortion, Septic; Administration, Topical; Chorionic Gonadotropin; Curettage; Dia

1974
[Considerations and research on febrile convulsions].
    Minerva pediatrica, 1974, Apr-14, Volume: 26, Issue:13

    Topics: Anticonvulsants; Brain Diseases; Child, Preschool; Diagnosis, Differential; Diazepam; Electroencepha

1974
[Fever convulsions].
    Deutsche medizinische Wochenschrift (1946), 1972, Oct-20, Volume: 97, Issue:42

    Topics: Child, Preschool; Diazepam; Electroencephalography; Epilepsy; Female; Fever; Humans; Long-Term Care;

1972
[Effect of treatment with inactivated vaccinia virus (vaccinia antigen) on the course of fever in primary smallpox vaccination in adults].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, praventive Medizin, 1972, Volume: 156, Issue:1

    Topics: Adult; Aminopyrine; Antigens; Diazepam; Fever; Humans; Smallpox; Smallpox Vaccine; Time Factors; Vac

1972
Hyperthermia, muscle rigidity, and uncoupling in skeletal muscle mitochondria in rats treated with halothane and 2,4-dinitrophenol.
    Anesthesiology, 1973, Volume: 38, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Body Temperature; Dactinomycin; Diazepam; Dinitrophenols; Drug Syne

1973
[Convulsions in children].
    La Vie medicale au Canada francais, 1973, Volume: 2, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Birth Injuries; Brain Diseases; Brain Injuries; Child; Child, Pr

1973
The management of febrile convulsions.
    Tropical doctor, 1973, Volume: 3, Issue:2

    Topics: Administration, Oral; Aspirin; Child, Preschool; Diazepam; Fever; Humans; Infant; Injections, Intram

1973
[Fever cramps--medical treatment. Etiology, clinical manifestations, prognosis. Based on a meeting at the Institutt for Farmakoterapi in November 1973].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Mar-10, Volume: 94, Issue:7

    Topics: Age Factors; Body Temperature; Child, Preschool; Diazepam; Female; Fever; Humans; Infant; Male; Musc

1974
Treatment of febrile convulsions.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:5

    Topics: Anticonvulsants; Aspirin; Child; Child, Preschool; Diazepam; Epilepsy, Temporal Lobe; Fever; Humans;

1974
Febrile convulsions in early childhood.
    British medical journal, 1972, Jun-24, Volume: 2, Issue:5816

    Topics: Child; Child, Preschool; Diazepam; Family Practice; Fever; Hospitalization; Humans; Infant; Seizures

1972
[Malignant hyperthermie--a case report].
    Der Anaesthesist, 1972, Volume: 21, Issue:5

    Topics: Anesthesia, General; Child; Diazepam; Female; Fever; Humans; Hypothermia, Induced; Lidocaine

1972
[Diagnosis of fever convulsions].
    Nordisk medicin, 1971, Oct-21, Volume: 86, Issue:42

    Topics: Body Temperature; Child, Preschool; Diazepam; Female; Fever; Humans; Infant; Male; Seizures

1971
[The use of diazepam as a sedative in infancy].
    Minerva medica, 1969, Nov-28, Volume: 60, Issue:95

    Topics: Diazepam; Female; Fever; Humans; Infant; Infant, Newborn; Male; Psychomotor Disorders; Sleep Initiat

1969
Pyrexial reactions during haemodialysis.
    British medical journal, 1971, Mar-06, Volume: 1, Issue:5748

    Topics: Acetaminophen; Albumins; Blood; Codeine; Diazepam; Female; Fever; Humans; Kidneys, Artificial; Male;

1971