Page last updated: 2024-10-28

hydroxychloroquine and Fever

hydroxychloroquine has been researched along with Fever in 34 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"The authors describe the first case of drug rash with eosinophilia and systemic symptoms syndrome caused by hydroxychloroquine treatment in a male patient affected by seronegative arthritis."7.74Hydroxychloroquine-induced DRESS syndrome. ( Arcaro, G; Bambara, LM; Biasi, D; Caramaschi, P; Marchetta, A; Volpe, A, 2008)
" This patient was diagnosed with drug rash with eosinophilia and systemic symptoms syndrome 4 weeks after starting sulfasalazine and 5 weeks after starting hydroxychloroquine for rheumatoid arthritis."4.12Drug rash with eosinophilia and systemic symptoms syndrome masquerading as a lymphoproliferative disorder in a young adult on immunosuppressive therapy for rheumatoid arthritis: a case report. ( Hyser, E, 2022)
"The authors describe the first case of drug rash with eosinophilia and systemic symptoms syndrome caused by hydroxychloroquine treatment in a male patient affected by seronegative arthritis."3.74Hydroxychloroquine-induced DRESS syndrome. ( Arcaro, G; Bambara, LM; Biasi, D; Caramaschi, P; Marchetta, A; Volpe, A, 2008)
"Since the emergence of coronavirus disease 2019 (COVID-19), neurological symptoms, syndromes, and complications associated with this multi-organ viral infection have been reported and the various aspects of neurological involvement are increasingly uncovered."2.72Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature. ( Aghavali, S; Babadi, M; Daraie, P; Emamikhah, M; Jalili, M; Mehrabani, M; Mohaghegh, F; Pouranian, M; Rohani, M; Zaribafian, M, 2021)
"Initial hospitalization and treatment for fever of unknown origin did not yield improvement."1.91The co-occurrence of Kikuchi-Fujimoto disease and systemic lupus erythematosus: a case report. ( Binafar, H; Kaveh, R; Mirkamali, H; Pourzand, P; Rukerd, MRZ; Shoaie, S; Yousefi, M, 2023)
"Fever is recorded in the majority of children (77."1.72Kikuchi Disease in Children: Case Report and Review of the Literature. ( Abdu, A; Bijker, EM; Pajkrt, D, 2022)
"Hiccups are involuntary diaphragmatic muscle contractions with early glottis closure terminating inspiration."1.62Persistent hiccup: A rare presentation of COVID-19. ( Bakheet, N; El-Shazly, M; Fouad, R; Hussin, W; Kassem, AM, 2021)
"Moreover, PTSD in patients with COVID-19 is not associated with the increased risk of CFS."1.62Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19. ( Aalipour, MA; Darazam, IA; Ghorbani, F; Pakdaman, H; Ramezani, M; Sagharichi, M; Simani, L, 2021)
"The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy."1.56Coronavirus disease 2019 in pregnancy: early lessons. ( Baptiste, C; Breslin, N; D'Alton, M; Fuchs, K; Goffman, D; Gyamfi-Bannerman, C; Miller, R, 2020)
"Key words: Coronavirus disease 2019 (COVID-19), Meningoencephalitis, Pneumonia."1.56A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19). ( Khan, MA, 2020)
"Rowell's syndrome is a rare disorder characterised by an association of lupus erythematosus with erythema multiforme (EM)-like skin lesions."1.56Rowell's syndrome: a rare but distinct entity in rheumatology. ( Chandra, A; Karmakar, P; Ray, AK; Saha, SK, 2020)
"She also had developed anasarca two years prior to presentation."1.39Systemic lupus erythematosus and granulomatous lymphadenopathy. ( Dhakal, AK; Shah, SC; Shakya, A; Shakya, H; Shiva, RK; Shrestha, D, 2013)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.94)18.2507
2000's1 (2.94)29.6817
2010's5 (14.71)24.3611
2020's27 (79.41)2.80

Authors

AuthorsStudies
Abdu, A1
Pajkrt, D1
Bijker, EM1
Hyser, E1
Yousefi, M1
Rukerd, MRZ1
Binafar, H1
Shoaie, S1
Mirkamali, H1
Pourzand, P1
Kaveh, R1
Gutta, S1
Das, S1
Kodiatte, TA1
Vimala, LR1
Spezzani, V1
Piunno, A1
Iselin, HU1
Fernández-Ruiz, M1
Andrés, A1
Loinaz, C1
Delgado, JF1
López-Medrano, F1
San Juan, R1
González, E1
Polanco, N1
Folgueira, MD1
Lalueza, A1
Lumbreras, C1
Aguado, JM1
Wander, P1
Epstein, M1
Bernstein, D1
Aminian, A1
Kermansaravi, M1
Azizi, S1
Alibeigi, P1
Safamanesh, S1
Mousavimaleki, A1
Rezaei, MT1
Faridi, M1
Mokhber, S1
Pazouki, A1
Safari, S1
Juusela, A1
Nazir, M1
Gimovsky, M1
Bozzalla Cassione, E1
Zanframundo, G1
Biglia, A1
Codullo, V1
Montecucco, C1
Cavagna, L1
Medetalibeyoğlu, A1
Şenkal, N1
Çapar, G1
Köse, M1
Tükek, T1
Breslin, N1
Baptiste, C1
Miller, R1
Fuchs, K1
Goffman, D1
Gyamfi-Bannerman, C1
D'Alton, M1
Mattioli, M1
Fustini, E1
Gennarini, S1
Firouzabadi, FD1
Firouzabadi, MD1
Ghalehbaghi, B1
Jahandideh, H1
Roomiani, M1
Goudarzi, S1
Khan, MA2
Khan, S1
Ahmad, Z1
Khan, F1
Asif, H1
Zia-Ur-Rahman, A1
Gurkan, O1
Yilmaz, A1
Cengel, F1
Altunok, ES1
Ekin, EE1
Choi, NH1
Silver, ES1
Fremed, M1
Liberman, L1
Miao, H1
Li, H1
Yao, Y1
Wu, M1
Lu, C1
Wang, J1
Tian, M1
Li, Y1
Luo, P1
Gu, J1
Yuan, B1
Wang, S1
Zhao, X1
Gan, W1
Zhao, D1
Chandra, A1
Saha, SK1
Ray, AK1
Karmakar, P1
Zurita, MF1
Iglesias Arreaga, A1
Luzuriaga Chavez, AA1
Zurita, L1
Bakheet, N1
Fouad, R1
Kassem, AM1
Hussin, W1
El-Shazly, M1
Matangila, JR1
Nyembu, RK1
Telo, GM1
Ngoy, CD1
Sakobo, TM1
Massolo, JM1
Muyembe, BM1
Mvwala, RK1
Ilunga, CK1
Limbole, EB1
Ntalaja, JM1
Kongo, RM1
Mondal, R1
Ganguly, U1
Deb, S1
Shome, G1
Pramanik, S1
Bandyopadhyay, D1
Lahiri, D1
Ortiz Molina, E1
Hernandez Pailos, R1
Pola Guillen, M1
Pascual Pedreno, A1
Rodriguez Rodriguez, E1
Hernandez Martinez, A1
Emamikhah, M1
Babadi, M1
Mehrabani, M1
Jalili, M1
Pouranian, M1
Daraie, P1
Mohaghegh, F1
Aghavali, S1
Zaribafian, M1
Rohani, M1
Simani, L1
Ramezani, M1
Darazam, IA1
Sagharichi, M1
Aalipour, MA1
Ghorbani, F1
Pakdaman, H1
Chang, MC1
Kim, TU1
Park, D1
Lazovic, B1
Zlatkovic-Svenda, M1
Jasarovic, D1
Stevanovic, D1
Montejo, M1
Goikoetxea, J1
Mularoni, A1
Blanco, MJ1
Gaafar, A1
Boado, MV1
Marín, M1
Aramendi, JI1
Shrestha, D1
Dhakal, AK1
Shiva, RK1
Shakya, A1
Shah, SC1
Shakya, H1
Chen, PH1
Huang, YF1
Tang, CW1
Wann, SR1
Chang, HT1
Volpe, A1
Marchetta, A1
Caramaschi, P1
Biasi, D1
Bambara, LM1
Arcaro, G1
McGalliard, J1
Bell, AL1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Immunogenicity of the SARS-CoV2 Vaccine in Solid Organ Transplantation (Lung and / or Liver) Adult Recipients[NCT05116748]200 participants (Anticipated)Observational2021-10-01Active, not recruiting
Incidence of COVID-19 Test Conversion in Post-surgical Patients[NCT04392323]111 participants (Actual)Interventional2020-05-13Completed
Efficacy and Security of the Magnesium and Vitamin D Combination as Adjuvant Treatment of Post-COVID Syndrome. A Randomised Double-blind Clinical Trial[NCT05630339]150 participants (Actual)Interventional2022-01-30Completed
Neuropsychological Sequelae as a Risk Factor for Long COVID-19 Fatigue[NCT05323318]200 participants (Anticipated)Observational2022-04-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hydroxychloroquine and Fever

ArticleYear
Update on recommendations for the diagnosis and treatment of SARS-CoV-2 infection in children.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020, Volume: 39, Issue:12

    Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Asymptomatic Diseases; Betacoronavirus; Biomarke

2020
Meningoencephalitis associated with COVID-19: a systematic review.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Azithromycin; Confusion; Cough; COVID-19; COVID-19 Drug Treatment; Dy

2021
Opsoclonus-myoclonus syndrome, a post-infectious neurologic complication of COVID-19: case series and review of literature.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Anticonvulsants; Ataxia; Azithromycin; Clonazepam; Cough; COVID-19; COVID-19 Drug Treatment;

2021

Other Studies

31 other studies available for hydroxychloroquine and Fever

ArticleYear
Kikuchi Disease in Children: Case Report and Review of the Literature.
    The Pediatric infectious disease journal, 2022, 03-01, Volume: 41, Issue:3

    Topics: Child; Diagnosis, Differential; Female; Fever; Histiocytic Necrotizing Lymphadenitis; Humans; Hydrox

2022
Drug rash with eosinophilia and systemic symptoms syndrome masquerading as a lymphoproliferative disorder in a young adult on immunosuppressive therapy for rheumatoid arthritis: a case report.
    Journal of medical case reports, 2022, Sep-05, Volume: 16, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Rheumatoid; Drug Hypersensitivity Syndrome; Eosinophilia; E

2022
The co-occurrence of Kikuchi-Fujimoto disease and systemic lupus erythematosus: a case report.
    Journal of medical case reports, 2023, Oct-27, Volume: 17, Issue:1

    Topics: Female; Fever; Histiocytic Necrotizing Lymphadenitis; Humans; Hydroxychloroquine; Lupus Erythematosu

2023
Organising pneumonia in Rhupus syndrome.
    BMJ case reports, 2019, Dec-19, Volume: 12, Issue:12

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis; Cough; Diagnosis, Differential; Drug Ther

2019
Benign COVID-19 in an immunocompromised cancer patient -  the case of a married couple.
    Swiss medical weekly, 2020, 04-06, Volume: 150

    Topics: Anti-Bacterial Agents; Antiviral Agents; Betacoronavirus; Breast Neoplasms; Cobicistat; Coronavirus

2020
COVID-19 in solid organ transplant recipients: A single-center case series from Spain.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020, Volume: 20, Issue:7

    Topics: Aged; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; Drug Combinations; Female

2020
COVID-19 Presenting as Acute Hepatitis.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:6

    Topics: Antimalarials; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Fever; Hepatitis, Viral, H

2020
Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak.
    Obesity surgery, 2020, Volume: 30, Issue:9

    Topics: Adult; Anti-Retroviral Agents; Betacoronavirus; Coronavirus Infections; Cough; COVID-19; Dyspnea; Fa

2020
Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Blood Gas Analysi

2020
COVID-19 infection in a northern-Italian cohort of systemic lupus erythematosus assessed by telemedicine.
    Annals of the rheumatic diseases, 2020, Volume: 79, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Azathioprine; Betacoronavirus; Clinical Labora

2020
Characteristics of the initial patients hospitalized for COVID-19: a single-center report
    Turkish journal of medical sciences, 2020, Aug-26, Volume: 50, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhi

2020
Coronavirus disease 2019 in pregnancy: early lessons.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Acute Kidney Injury; Adult; Anesthesia, General; Anti-Bacterial Agents; Antihypertensive Agents; Azi

2020
Heart transplant recipient patient with COVID-19 treated with tocilizumab.
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:6

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Cardiomyopathy, Dilated; C

2020
Have the symptoms of patients with COVID-19 changed over time during hospitalization?
    Medical hypotheses, 2020, Volume: 143

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Coronavirus Infections; Cough; COVID-19; Diar

2020
A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19).
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anti-Bacterial Agents; Anticoagulants; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus;

2020
Diarrhoea: An Atypical Presentation of COVID-19.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Azithromycin; Betacoronavirus; Coronavirus; Coronavirus Infections; Cough; COVID-19; Diarrhea; Femal

2020
COVID-19 Pulmonary Infection with Pneumothorax in a Young Patient.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:6

    Topics: Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; Azithromycin; Betacoronavirus; Coronavirus;

2020
COVID-19 reveals Brugada pattern in an adolescent patient.
    Cardiology in the young, 2020, Volume: 30, Issue:11

    Topics: Antiviral Agents; Brugada Syndrome; C-Reactive Protein; Chest Pain; Consanguinity; Cough; COVID-19;

2020
Rowell's syndrome: a rare but distinct entity in rheumatology.
    BMJ case reports, 2020, Sep-23, Volume: 13, Issue:9

    Topics: Adolescent; Antibodies, Antinuclear; Antipyretics; Arthralgia; Drug Therapy, Combination; Erythema M

2020
SARS-CoV-2 Infection and COVID-19 in 5 Patients in Ecuador After Prior Treatment with Hydroxychloroquine for Systemic Lupus Erythematosus.
    The American journal of case reports, 2020, Sep-26, Volume: 21

    Topics: Adult; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID-19 Testing; Dyspnea;

2020
Persistent hiccup: A rare presentation of COVID-19.
    Respiratory investigation, 2021, Volume: 59, Issue:2

    Topics: Baclofen; Biomarkers; COVID-19; COVID-19 Testing; Fever; Hiccup; Humans; Hydroxychloroquine; Male; M

2021
Clinical characteristics of COVID-19 patients hospitalized at Clinique Ngaliema, a public hospital in Kinshasa, in the Democratic Republic of Congo: A retrospective cohort study.
    PloS one, 2020, Volume: 15, Issue:12

    Topics: Adult; Aged; Blood Coagulation; Chloroquine; Coinfection; Comorbidity; Cough; COVID-19; COVID-19 Dru

2020
COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: a retrospective analysis.
    Ginekologia polska, 2020, Volume: 91, Issue:12

    Topics: Adult; Anosmia; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; C-Reactive Protein; Cesarea

2020
Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Cough; COVID-19; COVID-19 Drug Treatment; Dementia; Drug Combinations

2021
Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Cough; COVID-19; COVID-19 Drug Treatment; Dementia; Drug Combinations

2021
Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Cough; COVID-19; COVID-19 Drug Treatment; Dementia; Drug Combinations

2021
Prevalence and correlates of chronic fatigue syndrome and post-traumatic stress disorder after the outbreak of the COVID-19.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Aged; Antiviral Agents; Cough; COVID-19; COVID-19 Drug Treatment; Dementia; Drug Combinations

2021
National early warning score on admission as risk factor for invasive mechanical ventilation in COVID-19 patients: A STROBE-compliant study.
    Medicine, 2021, May-14, Volume: 100, Issue:19

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Ea

2021
Systemic Lupus Erythematosus Presenting as Acute Lupus Pneumonitis.
    Archivos de bronconeumologia, 2018, Volume: 54, Issue:4

    Topics: Acute Disease; Aged; Chest Pain; Diagnosis, Differential; Dyspnea; Emergencies; Female; Fever; Human

2018
[Tropheryma wipplei endocarditis: a report of 3 cases].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2013, Volume: 26, Issue:2

    Topics: Actinomycetales Infections; Anti-Bacterial Agents; Anticoagulants; Doxycycline; Drug Therapy, Combin

2013
Systemic lupus erythematosus and granulomatous lymphadenopathy.
    BMC pediatrics, 2013, Nov-05, Volume: 13

    Topics: Antibodies, Antinuclear; Child; Connective Tissue Diseases; Diagnosis, Differential; Disease Progres

2013
Kikuchi-Fujimoto disease: an amazing response to hydroxychloroquine.
    European journal of pediatrics, 2010, Volume: 169, Issue:12

    Topics: Biopsy; Child; Diagnosis, Differential; Enzyme Inhibitors; Female; Fever; Histiocytic Necrotizing Ly

2010
Hydroxychloroquine-induced DRESS syndrome.
    Clinical rheumatology, 2008, Volume: 27, Issue:4

    Topics: Antirheumatic Agents; Arthritis; Eosinophilia; Exanthema; Fever; Humans; Hydroxychloroquine; Male; M

2008
Acquired Brown's syndrome in systemic lupus erythematosus: another ocular manifestation.
    Clinical rheumatology, 1990, Volume: 9, Issue:3

    Topics: Adult; Diclofenac; Diplopia; Fever; Humans; Hydroxychloroquine; Ibuprofen; Lupus Erythematosus, Syst

1990