Page last updated: 2024-11-03

primaquine and Fever

primaquine has been researched along with Fever in 15 studies

Primaquine: An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
primaquine : An N-substituted diamine that is pentane-1,4-diamine substituted by a 6-methoxyquinolin-8-yl group at the N(4) position. It is a drug used in the treatment of malaria and Pneumocystis pneumonia.

Fever: An abnormal elevation of body temperature, usually as a result of a pathologic process.

Research Excerpts

ExcerptRelevanceReference
"A safe and reproducible Plasmodium vivax infectious challenge method is required to evaluate the efficacy of malaria vaccine candidates."2.76Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers. ( Arévalo-Herrera, M; Echavarría, JF; Epstein, JE; Herrera, S; Jordán-Villegas, A; Palacios, R; Ramírez, O; Richie, TL; Rocha, L; Solarte, Y; Vélez, JD, 2011)
" These data inform discussions on safe and effective primaquine dosing and future malaria elimination strategies for Haiti."1.40Glucose-6-phosphate dehydrogenase deficiency A- variant in febrile patients in Haiti. ( Carter, TE; Maloy, H; Mulligan, CJ; Okech, BA; Romain, JR; St Victor, Y; von Fricken, M, 2014)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, N1
Ahlawat, RS1
Singh, H1
Sharma, C1
Anuradha, S1
Gunawardena, S1
Daniels, RF1
Yahathugoda, TC1
Weerasooriya, MV1
Durfee, K1
Volkman, SK1
Wirth, DF1
Karunaweera, ND1
Redditt, V1
Bogoch, I1
Rashid, M1
Mansanguan, C1
Phumratanaprapin, W1
Carter, TE1
Maloy, H1
von Fricken, M1
St Victor, Y1
Romain, JR1
Okech, BA1
Mulligan, CJ1
Redig, AJ1
Vaidya, A1
Price, C1
Katz, JT1
Maguire, JH1
Philip, KE1
Baddeley, R1
Jenkins, M1
Bovill, B1
Vásquez, AM1
Sanín, F1
Alvarez, LG1
Tobón, A1
Ríos, A1
Blair, S1
Herrera, S1
Solarte, Y1
Jordán-Villegas, A1
Echavarría, JF1
Rocha, L1
Palacios, R1
Ramírez, O1
Vélez, JD1
Epstein, JE1
Richie, TL1
Arévalo-Herrera, M1
Zaki, SA1
Shanbag, P1
Redmond, P1
O'Shea, B1
Crowe, M1
Fernando, SD1
Wickremasinghe, AR1
Dubberke, ER1
Weil, GJ1
McGlone, R1
Mulik, R1
Seeler, RA1
Miller, RA1
Lin, CH1
Lin, SK1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Susceptibility of Naive and Pre-immune Volunteers to Infectious Challenge With Viable Plasmodium Vivax Sporozoites.[NCT01585077]Phase 1/Phase 216 participants (Actual)Interventional2012-10-31Completed
Evaluation of the Protective Efficacy of a Vaccine Derived From the Synthetic CS Protein of Plasmodium Vivax[NCT02083068]Phase 232 participants (Actual)Interventional2014-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for primaquine and Fever

ArticleYear
[Therapeutic efficacy of a regimen of artesunate-mefloquine-primaquine treatment for Plasmodium falciparum malaria and treatment effects on gametocytic development].
    Biomedica : revista del Instituto Nacional de Salud, 2009, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Drug Resistance; Drug Th

2009
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.
    The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:2 Suppl

    Topics: Adult; Animals; Antimalarials; Chloroquine; Duffy Blood-Group System; Female; Fever; Humans; Malaria

2011
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.
    The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:2 Suppl

    Topics: Adult; Animals; Antimalarials; Chloroquine; Duffy Blood-Group System; Female; Fever; Humans; Malaria

2011
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.
    The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:2 Suppl

    Topics: Adult; Animals; Antimalarials; Chloroquine; Duffy Blood-Group System; Female; Fever; Humans; Malaria

2011
Consistent safety and infectivity in sporozoite challenge model of Plasmodium vivax in malaria-naive human volunteers.
    The American journal of tropical medicine and hygiene, 2011, Volume: 84, Issue:2 Suppl

    Topics: Adult; Animals; Antimalarials; Chloroquine; Duffy Blood-Group System; Female; Fever; Humans; Malaria

2011

Other Studies

13 other studies available for primaquine and Fever

ArticleYear
Pneumocystis jirovecii infection of bilateral adrenal glands in an immunocompetent adult: a case report.
    The journal of the Royal College of Physicians of Edinburgh, 2019, Volume: 49, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Glands; Anti-Bacterial Agents; Antimalarials; Clindamycin; Drug Ther

2019
Case report of Plasmodium ovale curtisi malaria in Sri Lanka: relevance for the maintenance of elimination status.
    BMC infectious diseases, 2017, 04-24, Volume: 17, Issue:1

    Topics: Adult; Antimalarials; Chloroquine; Fever; Humans; Liberia; Malaria; Malaria, Vivax; Male; Molecular

2017
A 38-year-old man with fever and a history of malaria.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018, 09-10, Volume: 190, Issue:36

    Topics: Adult; Antimalarials; Chloroquine; Diagnosis, Differential; Fever; Humans; Malaria, Vivax; Male; Pri

2018
Concomitant
    BMJ case reports, 2018, Dec-09, Volume: 11, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Antimalarials; Chloroquine; Coinfection; Female; Fever; Humans; Malari

2018
Glucose-6-phosphate dehydrogenase deficiency A- variant in febrile patients in Haiti.
    The American journal of tropical medicine and hygiene, 2014, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anemia, Hemolytic; Antimalarials; Child; Child,

2014
Interactive medical case. A chilly fever.
    The New England journal of medicine, 2014, Oct-16, Volume: 371, Issue:16

    Topics: Adult; Antimalarials; Chloroquine; Diagnosis, Differential; Fever; Humans; Life Cycle Stages; Malari

2014
Fever in the returning traveller: the importance of sensitivity.
    BMJ case reports, 2015, Oct-13, Volume: 2015

    Topics: Adult; Antimalarials; Cameroon; Chloroquine; Diagnosis, Differential; Fever; Follow-Up Studies; Huma

2015
Plasmodium vivax malaria presenting with skin rash--a case report.
    Journal of vector borne diseases, 2011, Volume: 48, Issue:4

    Topics: Antimalarials; Child; Chloroquine; Exanthema; Female; Fever; Histamine Antagonists; Humans; Malaria,

2011
'Not another UTI ... '.
    Age and ageing, 2012, Volume: 41, Issue:4

    Topics: Aged, 80 and over; Antimalarials; Fever; Humans; Malaria; Male; Plasmodium ovale; Primaquine; Recurr

2012
The clinical and epidemiological features of childhood malaria in a moderately endemic area of Sri Lanka.
    The Southeast Asian journal of tropical medicine and public health, 2002, Volume: 33, Issue:4

    Topics: Administration, Oral; Antimalarials; Arthralgia; Case-Control Studies; Child; Child Welfare; Child,

2002
A woman from Honduras with a painful forearm and fever.
    The American journal of tropical medicine and hygiene, 2008, Volume: 78, Issue:5

    Topics: Adult; Animals; Antimalarials; Female; Fever; Honduras; Humans; Malaria, Vivax; Mefloquine; Pain; Pl

2008
Hypnozoites in Bradford.
    Archives of emergency medicine, 1988, Volume: 5, Issue:4

    Topics: Animals; Child, Preschool; Chloroquine; England; Fever; Humans; Infant, Newborn; Malaria; Male; Plas

1988
Transfusion-induced malaria. Plasmodium vivax in a 5-month-old child.
    American journal of diseases of children (1960), 1973, Volume: 125, Issue:1

    Topics: Chloroquine; Fever; Hemolysis; Hepatomegaly; Humans; Infant; Malaria; Male; Plasmodium vivax; Primaq

1973